Bronopol is a highly active antimicrobial chemical compound. It was invented by The Boots Company PLC, Nottingham, England in the early 1960s and first applications were as a preservative for pharmaceuticals. Bronopol's low mammalian toxicity and exceptional activity against bacteria ensured that it became popular as a preservative in many consumer products such as shampoos and cosmetics. It was subsequently taken up as an effective antimicrobial in many industrial environments such as paper mills, oil exploration and production facilities, as well as cooling water disinfection plants. Today, Bronopol is used in consumer products as an effective preservative agent, as well as a wide variety of industrial applications. The use of Bronopol in personal care products has declined since the late 1980s due to the recognized potential for nitrosamine formation.
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