Media

An advance toward an “electronic nose” urine test for TB

2:21 PM, 4th August 2011
An advance toward an “electronic nose” urine test for TB
Tuberculosis, shown in this chest X-ray of an infected patient, may be diagnosed in the future using a fast, inexpensive urine test. (C) iStock.

 

WASHINGTON DC, US: Scientists are reporting an advance toward a fast, inexpensive urine test to detect and monitor the effectiveness of treatment for tuberculosis (TB), which is on a rampage in the developing world. Their study appears in the ACS’ journal Analytical Chemistry.

A team led by Virander Singh Chauhan and Ranjan Kumar Nanda noted that TB strikes an estimated 10 million people and kills 3 million each year, mostly in developing countries. Health care workers diagnose the disease by identifying the TB bacterium in sputum or blood samples. But current tests tend to be time-consuming, sometimes taking days or weeks to give results. The tests also require the use of specially trained personnel or expensive equipment that might not be available in some areas.

The scientists describe an advance toward a test that overcomes these drawbacks. They analyzed so-called volatile organic compounds (VOCs) - substances that evaporate easily in the air - present in the urine of TB patients and compared them with VOCs in the urine of healthy patients. The scientists found that infection with TB produces a distinct pattern of certain VOCs in much the same way that distinct fingerprint patterns can identify individuals. Identification of these patterns sets the stage for developing a portable “electronic nose” that can quickly sniff urine samples to detect TB, the scientists suggest.

The authors acknowledged funding from the Government of India’s Department of Biotechnology and International Centre for Genetic Engineering and Biotechnology, New Delhi.

© 2011 American Chemical Society News

 

0 Comments

Login

Your Comments (Up to 2000 characters)
Please respect our community and the integrity of its participants. WOC reserves the right to moderate and approve your comment.

Related News


Unrecognised volcanic process similar to chocolate manufacturing discovered

SOUTHAMPTON, UK: Scientists from the University of Southampton have discovered a previously unrecognised volcanic process, similar to one that is used ...

Read more
Shaw bags Wolf Creek’s nuclear power plant contract in Burlington

BATON ROUGE, US: The Shaw Group has signed a new contract with Wolf Creek Nuclear Operating Corporation to provide maintenance and other support servi ...

Read more
Dow acquires Lightscape Materials, adds phosphor to LED portfolio

PHILADELPHIA, US: Dow Electronic Materials, a unit of Dow Chemical Company, acquired Lightscape Materials Inc, a spin-off of SRI International. Major ...

Read more
National Academy of Sciences to review EPA’s IRIS assessment process

WASHINGTON DC, US: The Environmental Protection Agency (EPA) announced that the National Academy of Sciences (NAS) will conduct a comprehensive revi ...

Read more
GSK to acquire 100 per cent stake in Cellzome for $99 million

LONDON UK: GlaxoSmithKline (GSK) has entered into an agreement to acquire those shares it does not currently own in Cellzome, a leader in the developm ...

Read more
Acron to acquire 66 per cent stake in Azoty Tarnow

MOSCOW, RUSSIA: Russian fertiliser maker Acron has proposed to buy up to 66 per cent of major Polish chemical firm Azoty Tarnow for 36 Polish zloty ($ ...

Read more
Copyright © 2014. Kimberlite Softwares Pvt. Ltd., India. All rights reserved.
World of Chemicals.