An advance toward “electronic nose” urine test TB


An advance toward an “electronic nose” urine test for TB

2:21 PM, 4th August 2011
An advance toward an “electronic nose” urine test for TB
Tuberculosis, shown in this chest X-ray of an infected patient, may be diagnosed in the future using a fast, inexpensive urine test. (C) iStock.


WASHINGTON DC, US: Scientists are reporting an advance toward a fast, inexpensive urine test to detect and monitor the effectiveness of treatment for tuberculosis (TB), which is on a rampage in the developing world. Their study appears in the ACS’ journal Analytical Chemistry.

A team led by Virander Singh Chauhan and Ranjan Kumar Nanda noted that TB strikes an estimated 10 million people and kills 3 million each year, mostly in developing countries. Health care workers diagnose the disease by identifying the TB bacterium in sputum or blood samples. But current tests tend to be time-consuming, sometimes taking days or weeks to give results. The tests also require the use of specially trained personnel or expensive equipment that might not be available in some areas.

The scientists describe an advance toward a test that overcomes these drawbacks. They analyzed so-called volatile organic compounds (VOCs) - substances that evaporate easily in the air - present in the urine of TB patients and compared them with VOCs in the urine of healthy patients. The scientists found that infection with TB produces a distinct pattern of certain VOCs in much the same way that distinct fingerprint patterns can identify individuals. Identification of these patterns sets the stage for developing a portable “electronic nose” that can quickly sniff urine samples to detect TB, the scientists suggest.

The authors acknowledged funding from the Government of India’s Department of Biotechnology and International Centre for Genetic Engineering and Biotechnology, New Delhi.

© 2011 American Chemical Society News




Your Comments (Up to 2000 characters)
Please respect our community and the integrity of its participants. WOC reserves the right to moderate and approve your comment.

Related News

BASF to explore new investment in Brazil

With a special focus on the growing South American market, BASF plans to invest in Brazil. The feasibility study is being conducted on world-scale p ...

Read more
Technip, BASF sign umbrella contract in chemical, petrochemical fields

PARIS, FRANCE: Technip was awarded by BASF an engineering partner umbrella service contract for chemical and petrochemical projects.   Both ...

Read more
Lanxess posts higher earnings on higher volumes and pricing

  Q1 EBITDA pre € 322 million, up 38 per cent Q1 sales € 2.1 billion, up 29 per cent yr-on-yr Q1 net profit € 166 million, up ...

Read more
Pfenex’s strategic alliance with SAFC for biopharmaceuticals

  The alliance will strengthen technology capabilities in the areas of microbial strain engineering, production of complex protein therapeutics ...

Read more
Elevance acquires Delta BioFuels facility in Natchez

  NATCHEZ, US: Elevance Renewable Sciences Inc has acquired the Delta BioFuels facility in Adams County. The company intends to convert the faci ...

Read more
BASF to take over RWE’s 50 per cent share in Zandvliet power plant

  LUDWIGSHAFEN, GERMANY: BASF and the German energy company RWE agreed that BASF Antwerpen NV will take over RWE’s 50 per cent share in Za ...

Read more
Copyright © 2014. Kimberlite Softwares Pvt. Ltd., India. All rights reserved.
World of Chemicals.