1500 Chemicals in Coffee | Prevent diabetes & Alzheimer disease | Chemistry Articles

1500 chemicals in Coffee!

Chemicals in Coffee - WorldOfChemicals

Did anyone know where coffee plant was originated?

Coffee plant originated in Africa and Madagascar.Coffee has become a universal and almost indispensable beverage in the modern dietary.It is a very reliable friend, the kind of friend who plays an important role in the various activities we perform during the day.

Recent evidence suggests coffee could help prevent type 2 diabetes and Alzheimer disease

Different groups of chemicals present in coffee are

150 Aliphatic compounds
56 Carbonyl compounds
9 Sulfur containing compounds
20 Alicyclic compounds
10 Ketones
60 Aromatic benzenoid compounds
16 Phenols
300 Heterocyclic compounds
74 Furans
10 Hydrofurans
37 Pyrroles
9 Pyridines
2 Quinolines
70 Pyrazines
10 Quinoxalines
3 Indoles
23 Thiophens
3 Thiophenones
28 Thiazoles
28 Oxazole

Though every one enjoying having coffee but any one thought about what is the chemistry of coffee that makes us so desirable?

Simple answer for this is coffee beans aroma

The coffee bean is where the chemistry of coffee begins and the aroma is what gives you the kind of flavor that you taste.

Coffee contains huge numbers of compounds, that includes

  • ~ 800 - 1000 aroma compounds
  • Caffeine
  • Carbohydrates
  • Chlorogenic acids
  • Trigonelline
  • Lipids
  • Melanoidins
  • Volatile compounds

Caffeine [1,3,7-trimethyl-xanthine]

Caffeine a purine alkaloid is a secondary metabolite of the coffee plant.Caffeine is the most widely used psychoactive substance in the preparation of coffee. It makes the people awake for longer time.

Caffeine affects cardiovascular and nervous system.It also increases the metabolism in humans.


Carbohydrates are the major constituents of coffee beans and serve various functions like binding of aroma, stabilization of foam, formation of sedimentation, and increased viscosity of the extract.

Chlorogenic acids

Chlorogenic acids (CGA) are cinnamic acid derivatives with biological effects mostly related to their antioxidant and anti-in?ammatory activities.

Benefits of chlorogenic acids

Reduction of the relative risk of

  • Cardiovascular disease
  • Diabetes type 2
  • Alzheimer’s disease and
  • Antibacterial activities


Trigonelline is an alkaloid found in coffee.It will help to prevent dental caries by preventing the bacteria Streptococcus mutans from adhering to teeth.

Pros and cons of coffee


  • The major content of coffee i.e., caffeine increases intellectual activity when fatigued or bored
  • Caffeine speeds up fat metabolism during exercise
  • Prevents cirrhosis of liver
  • Decreases the risk of Parkinson’s disease
  • Reduces the incidence of kidney stones


  • Coffee causes constriction of the blood vessels
  • Causes digestive system disorders
  • Decreases quality of sleep


[1] © From http://www.rsc.org/images/Coffee%20-%20Chemistry%20in%20Every%20Cup_tcm18-201245.pdf
[2] © From http://humantouchofchemistry.com/the-chemistry-that-brews-in-your-cup-of-coffee.htm
[3] © From http://www.elsevierdirect.com/brochures/conap2/PDFs/Vol3_Chemistry_of_Coffee_lr.pdf
[4] © From http://www.pnf.org/coffeeedited041001.pdf 

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