Joyce Jacobson Kaufman – introducer of conformational topology - WorldOfChemicals

Joyce Jacobson Kaufman – introducer of conformational topology

Article on Joyce Jacobson Kaufman

Biography & contributions

Joyce Jacobson Kaufman is a Jewish American chemist born on June 21, 1923. Kaufman’s contributions towards chemistry are introducing the phenomenon called conformational topology, described new method for coding and retrieving carcinogenic hydrocarbons.

Kaufman was the receiver of many notable awards and notes such as Garvan Medical Award of the American Chemical Society in the year of 1973, Woman of Achievement Award in the year of 1974.

Kaufman is also noted for other contributions like carrying out the first all-valence-electron, three-dimensional quantum-chemical calculations, and for research on the clinical effects of tranquilizers and narcotic drugs.

Facts about tranquilizers

Tranquilizers are a type of drugs that is used to reduce anxiety, fear, tension, agitation, and related states of mental disturbance. Tranquilizers classified into two main classes

  • Major tranquilizers
  • Minor tranquilizers

Major tranquilizers are also known as antipsychotic agents or neuroleptics, because they are used to treat major states of mental disturbance in schizophrenics and other psychotic patients. By contrast, minor tranquilizers also known as antianxiety agents or anxiolytics, are used to treat milder states of anxiety and tension in healthy individuals or people with less serious mental disorders.

The major and minor tranquilizers bear only a superficial resemblance to each other, and the trend has been to drop the use of the word tranquilizer altogether in reference to such drugs, though the term persists in popular usage. Major tranquilizers are highly selective in alleviating the delusions, hallucinations, and disordered thinking of schizophrenics and other psychotic patients.

The principal minor tranquilizers are the benzodiazepines. These drugs have a calming effect and eliminate both the physical and psychological effects of anxiety or fear.

Narcotic drugs

Narcotics occurring naturally in the opium poppy have been used since ancient Greek times, both for relieving pain and for producing euphoria. The main therapeutic use of narcotics is for pain relief, and hence they are often called narcotic analgesics.

Narcotics not only relieve pain but also seem to reduce suffering, worry, fear, and panic associated with severe pain. Narcotics act at these receptors to produce their many effects, whereas narcotic antagonists block these receptors and prevent narcotics from reaching them and exerting their actions.

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