Leopold Gmelin – discoverer of Gmelin Test

Leopold Gmelin – discoverer of Gmelin Test

Leopold Gmelin – discoverer of Gmelin Test

Biography & Contributions

Leopold Gmelin was a German chemist born on August 02, 1788 – died on April 13, 1853. Gmelin was remembered for his discovery of Gmelin Test.

Gmelin also worked on red prussiate / Potassium ferricyanide. He was also dealt with physiology, mineralogy and chemistry.

Gmelin's first physiological work was his dissertation on the black pigment of oxen and calves eyes. His most important physiological work was the 1826 released digestion by experiments, which he made together with Friedrich Tiedemann. By these experiments they found hydrochloric acid, and bile, in which Gmelin and Tiedemann among others discovered cholesterol and taurine.

The mineralogical works of Gmelin were analyses of various Hauyne Mineral. His chemical achievements include the discovery of the Croconic acid, he thus had synthesized the first cyclic organic compound

Taurine Chemical Details

Taurine is an organic acid widely distributed in animal tissues. It is a major constituent of bile and can be found in the large intestine, and accounts for up to 0.1% of total human body weight.Taurine has many fundamental biological roles, such as conjugation of bile acids, antioxidation, osmoregulation, membrane stabilization, and modulation of calcium signaling.

It is essential for cardiovascular function, and development and function of skeletal muscle, the retina, and the central nervous system. Taurine is unusual among biological molecules in being a sulfonic acid, while the vast majority of biologically occurring acids contain the more weakly acidic carboxyl group.

Taurine is a derivative of cysteine, an amino acid which contains a thiol group. Taurine is one of the few known naturally occurring sulfonic acids. Taurine is a major constituent of bile and can be found in the large intestine and in the tissues of many animals, including humans.

Taurine is conjugated via its amino terminal group with chenodeoxycholic acid and cholic acid to form the bile salts sodium taurochenodeoxycholate and sodium taurocholate.

Hauyne Mineral

Hauyne is a tectosilicate mineral with sulfate, with the formula Na3Ca (Si3Al3) O12 (SO4). It is a feldspathoid and a member of the sodalite group. Hauyne crystallizes in the isometric system forming rare dodecahedral or pseudo-octahedral crystals.

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