Akira Suzuki – discoverer of Suzuki reaction

Akira Suzuki – discoverer of Suzuki reaction

Akira Suzuki – discoverer of Suzuki reaction

Biography & Contributions

Akira Suzuki is a Japanese chemist and Nobel Prize Laureate born on September 12, 1930. Suzuki had received many prizes and awards like Weissberger-Williams lectureship Award in the year of 1986, Korean Chemical Society Award in the year of 1987, Chemical Society of Japan Award in the year of 1989, DowElanco lectureship Award in the year of 1995, The H. C. Brown Lecture Award in the year of 2000, Japan Academy Prize in the year of 2003 and Nobel Prize for Chemistry in the year of 2010.

Suzuki and Norio Miyaura developed Suzuki-Miyaura reaction or Suzuki coupling reaction.

Suzuki Reaction

Suzuki Reaction is the organic reaction that is classified as a coupling reaction where the coupling partners are a boronic acid with a halide catalyzed by a palladium (0) complex. It is widely used to synthesize poly-olefins, styrenes, and substituted biphenyls.

Suzuki reaction’s mechanism

It involves oxidative addition of palladium to the halide to form the organopalladium species, followed by this reaction with base an intermediate will form. These intermediates will undergoes transmetalation with boron-ate complex and gives organopalladium species. In further step is the formation of reductive elimination of the desired product, this restores the original palladium catalyst 1 which completes the catalytic cycle.


Biphenyl is an aromatic hydrocarbon compound. It is notable as a starting material for the production of polychlorinated biphenyls. Biphenyl is also an intermediate for the production of a host of other organic compounds such as emulsifiers, optical brighteners, crop protection products, and plastics. Biphenyl is insoluble in water, but soluble in typical organic solvents.

Biphenyl is produced industrially as a byproduct of the dealkylation of toluene to produce benzene Biphenyl occurs naturally in coal tar, crude oil, and natural gas and can be isolated from these sources via distillation.

Transmetalation Chemical Reaction

Transmetalation is a type of organometallic reaction that involves the transfer of ligands from one metal to another. This chemical reaction can be represented as

 M1-R + M2-R' → M1-R' + M2-R

Where R and R' can be, but are not limited to, an alkyl, aryl, alkynyl, allyl, halogen, or pseudo-halogen group.

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