Traugott Sandmeyer – discoverer of sandmeyer reaction

Traugott Sandmeyer – discoverer of sandmeyer reaction

Traugott Sandmeyer – discoverer of sandmeyer reaction

Biography & Contributions

Traugott Sandmeyer was a Swiss chemist born on September 15, 1854 – died on April 09, 1922. Sandmeyer is best known for his sandmeyer reaction, Sandmeyer isonitrosoacetanilide isatin synthesis, Sandmeyer diphenylurea isatin synthesis.

Sandmeyer was involved in the development of several dyes and invented a new synthesis for indigo. He also worked on the synthesis of isatin.

Sandmeyer Reaction

Sandmeyer reaction is a chemical reaction used to synthesize aryl halides from aryl diazonium salts. The reaction is a method for substitution of an aromatic amino group via preparation of its diazonium salt followed by its displacement with a nucleophile, often catalyzed by copper (I) salts.

Isatin Compound

Isatin is an indole derivative, forms a blue dye if it is mixed with sulfuric acid and crude benzene. Isatin is used as an intermediate in the syntheses of pirquinozol, talnetant, tacrine, and dibucaine.

Indigo Dye

Indigo is an organic compound with a distinctive blue color. It is used as a dye for cotton yarn, which is mainly for the production of denim cloth for blue jeans. Indigo is also used as a food colorant.

Indigo is among the oldest dyes to be used for textile dyeing and printing. Many Asian countries, such as India, China, Japan, and Southeast Asian nations have used indigo as a dye for centuries. Indigo is a dark blue crystalline powder that sublimes at 390-392°C. It is insoluble in water, alcohol, or ether, but soluble in DMSO, chloroform, nitrobenzene, and concentrated sulfuric acid.

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