Biography & contributions
Paul Greengard is born on December 11, 1925
Greengard is an American neuroscientist and Nobel laureate
Greengard founded the Pearl Meister Greengard Prize
In 1991 he got NAS Award in the Neurosciences
In 2000 Greengard Nobel Prize for Physiology or Medicine
He worked on dopamine and other neurotransmitters function
Greengard showed that there is protein phosphorylation chemical reaction involved in synaptic transmission which occurs in nervous system
Facts about dopamine
Dopamine is neurotransmitter in the brain that plays vital roles in a variety of different behaviors.
The major behaviors dopamine affects are
- Movement
- Cognition
- Pleasure
- Motivation
Dopamine is an essential component of the basal ganglia motor loop
It acts as the neurotransmitter responsible for controlling the exchange of information from one brain area to another
Dopamine also helps regulate movement and emotional responses, and it enables us not only to see rewards, but to take action to move toward them.
Dopamine deficiency results in Parkinson's disease, and people with low dopamine activity may be more prone to addiction.
Functions of dopamine
Dopamine is also used as medication.
It acts on the sympathetic nervous system.
Dopamine can leads to increased heart rate and blood pressure.
Dopamine cannot cross the blood-brain barrier, so dopamine given as a drug does not directly affect the central nervous system.
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