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Ebastine is a H1 antihistamine with low potential for causing drowsiness. It does not penetrate the blood–brain barrier to a significant amount and thus combines an effective block of the H1 receptor in peripheral tissue with a low incidence of central side effects, i.e. seldom causing sedation or drowsiness. Ebastine is a second-generation H1 receptor antagonist that is indicated mainly for allergic rhinitis and chronic idiopathic urticaria.
Setastine is an antihistamine used to treat allergies and rhinitis. It acts as a highly selective H1 receptor antagonist. It has no anticholinergic, antiadrenergic, or antiserotonergic effects.
Rupatadine is a second generation antihistamine and PAF antagonist used to treat allergies. It was discovered and developed by J. Uriach y Cia, S. A.
Clocinizine is an first-generation antihistamine of the phenylpiperazine class.
Mizolastine is a once daily, non-sedating antihistamine. It blocks H1 receptors and is commonly fast-acting. It does not prevent the actual release of histamine from mast cells, just prevents it binding to receptors. Side effects can include dry mouth and throat.
Desloratadine is a drug used to treat allergies. It is an active metabolite of loratadine. It is a tricyclic antihistamine, which has a selective and peripheral H1-antagonist action. It is an antagonist at histamine H1 receptors, and an antagonist at all subtypes of the muscarinic acetylcholine receptor. It has a long-lasting effect and in moderate and low doses, does not cause drowsiness because it does not readily enter the central nervous system.
Phenothiazine is used as a chemical stabilizer or inhibitor to prolong storage and shelf life of products like acryloyl chloride. It is sometimes used as an antihelminthic in livestock.They are used as inodilators in congestive heart failure.
Pyrrobutamine is an antihistamine and anticholinergic.
Levocetirizine is a third-generation non-sedative antihistamine, developed from the second-generation antihistamine cetirizine.It is the L-enantiomer of the cetirizine racemate. Levocetirizine works by blocking histamine receptors. It does not prevent the actual release of histamine from mast cells, but prevents it binding to its receptors.
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