Cardiovascular drugs used in cardiovascular diseases treatment heart attack, stroke, hypertension


Calcium Acetate

Calcium Acetate is a calcium salt of acetic acid. Calcium is a mineral essential for many cellular functions including nerve impulse transmission, muscle contraction, cardiac function, bone formation, and capillary and cell membrane permeability. Calcium acetate is administered orally to prevent or treat calcium deficiency and to treat hyperphosphatemia due to its phosphate-binding properties.


LEXXEL is indicated for the treatment of hypertension. This fixed combination drug is not indicated for the initial therapy of hypertension. It is a fixed-dose combination of the ACE inhibitor enalapril maleate and the highly vascular selective calcium antagonist felodipine.

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Unimax is a fixed-dose combination of the vascular selective calcium antagonist felodipine and the ACE inhibitor ramipril, for hypertension.

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Digoxin, a cardiac glycoside similar to digitoxin, is used to treat congestive heart failure and supraventricular arrhythmias due to reentry mechanisms, and to control ventricular rate in the treatment of chronic atrial fibrillation.

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Logimax is a a fixed-dose, once-daily combination of the vascular selective calcium antagonist, felodipine, and the cardioselective beta-blocker, metoprolol.Logimax is used to treat high blood pressure (hypertension).

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Nif-Ten is a combination containing two medicines: the beta-blocker atenolol and the calcium-channel blocker nifedipine, which are provided in one capsule. Nif-Ten is used to treat high blood pressure (hypertension) and/or angina. It interferes with the action of the nervous system on the heart and reduces the rate and force of heart muscle contraction and lowers blood pressure.

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Amrinone is a pyridine phosphodiesterase 3 inhibitor. It is a drug that may improve the prognosis in patients with congestive heart failure. Amrinone has been shown to increase the contractions initiated in the heart by high gain calcium induced calcium release (CICR). It is used in the treatment of congestive heart failure. It has been studied for use before coronary artery bypass surgery. it increases cardiac contractility, vasodilator, and it acts by inhibiting the breakdown of both cAMP and cGMP by the phosphodiesterase (PDE3) enzyme.

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Atenolol is a selective β1 receptor antagonist,a class of drugs used primarily in cardiovascular diseases.Atenolol is used for a number of conditions including: hypertension, angina, Long cough, acute myocardial infarction, supraventricular tachycardia, ventricular tachycardia, and the symptoms of alcohol withdrawal.It is also used to treat the symptoms of Graves' disease until antithyroid medication can take effect.Atenolol controls high blood pressure and angina but does not cure them.Atenolol is also used sometimes to prevent migraine headaches and to treat alcohol withdrawal, heart failure, and irregular heartbeat.

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Dopamine is a neurotransmitter that serves as a chemical messenger in the nervous system and permits individual nerve fibers (neurons) to communicate with each other. It belongs to the class of compounds known as monoamines, and more specifically to a subclass of chemicals called catecholamines. Dopamine can act either as an inhibitory mechanism or an excitatory mechanism in the nervous system, depending on the location of dopamine neurons, and the receiving characteristics of the next neuron in the chain. Dopamine is biosynthesized in the body (mainly by nervous tissue and the medulla of the adrenal glands) first by the hydroxylation of the amino acid L-tyrosine to L-DOPA via the enzyme tyrosine 3-monooxygenase, also known as tyrosine hydroxylase, and then by the decarboxylation of L-DOPA by aromatic L-amino acid decarboxylase. Dopamine is a brain chemical which produces feelings of satisfaction and pleasure. It is heavily secreted while falling in love and commonly found during the attraction phase of a relationship. It has many functions in the brain, including important roles in behavior and cognition, voluntary movement, motivation, punishment and reward, inhibition of prolactin production (involved in lactation and sexual gratification), sleep, mood, and attention, working memory, and learning. Dopaminergic neurons (i.e., neurons whose primary neurotransmitter is dopamine) are present chiefly in the ventral tegmental area (VTA) of the midbrain, the substantia nigra pars compacta, and the arcuate nucleus of the hypothalamus.

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ISIS-CRP is an antisense drug that targets CRP, a protein produced in the liver. CRP levels increase dramatically during inflammatory disorders, and scientists have linked excessive amounts of CRP to coronary artery disease. Furthermore, a growing body of evidence from clinical trials implicates CRP in cardiovascular disease progression.

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