Dermatological drugs pharmaceuticals used in treating skin diseases

Dermatological-agents

Acitretin

Acitretin is a second generation retinoid. It is a metabolite of etretinate.It is taken orally, and is typically used for psoriasis.Acitretin works by inhibiting the excessive cell growth and keratinisation (process by which skin cells become thickened due to the deposition of a protein within them) seen in psoriasis. It therefore reduces the thickening of the skin, plaque formation and scaling.

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Adapalene

Adapalene is a third-generation topical retinoid.It is primarily used in the treatment of mild-moderate acne and is also used to treat keratosis pilaris as well as other skin conditions,topical treatment of comedo, papular and pustular acne (acne vulgaris) of the face, chest or back.Adapalene in small concentrations is a moderator of cellular differentiation, keratinization, and inflammatory processes. It has both exfoliating and anti-inflammatory effects.

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Minoxidil

Minoxidil is an antihypertensive vasodilator medication which also slows or stops hair loss and promotes hair regrowth.It is an orally effective direct acting peripheral vasodilator that reduces elevated systolic and diastolic blood pressure by decreasing peripheral vascular resistance. Minoxidil is also used topically to treat androgenetic alopecia.It is thought to promote the survival of human dermal papillary cells (DPCs) or hair cells by activating both extracellular signal-regulated kinase (ERK) and Akt and by preventing cell death by increasing the ratio of BCl-2/Bax. Minoxidil may stimulate the growth of human hairs by prolonging anagen through these proliferative and anti-apoptotic effects on DPCs. Minoxidil, when used as a vasodilator, acts by opening adenosine triphosphate-sensitive potassium channels in vascular smooth muscle cells.

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Rifaximin

Rifaximin is a semisynthetic, rifamycin-based non-systemic antibiotic, meaning that the drug will not pass the gastrointestinal wall into the circulation as is common for other types of orally administered antibiotics. It is used to treat diarrhea caused by E. coli.Rifaximin is a product of synthesis of rifamycin, an antibiotic with low gastrointestinal absorption and good antibacterial activity. It acts on the beta-subunit of the deoxyribonucleic acid (DNA)-dependent ribonucleic acid (RNA) polymerase enzyme of microorganisms to inhibit RNA synthesis.

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Etretinate

Etretinate is a medication used to treat severe psoriasis. It is a synthetic aromatic retinoid.It is an aromatic retinoid, and therefore highly lipophilic. It is stored and released from adipose tissue, so its effects can continue long after dosage stops. It is detectable in the plasma for up to three years following therapy.Etretinate is now used to treat T-cell lymphomas.

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Ulobetasol

Ulobetasol is a corticosteroid. It is used to reduce itching, redness, and swelling associated with many skin conditions.

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Clindamycin

Clindamycin is a lincosamide antibiotic. It is usually used to treat infections with anaerobic bacteria but can also be used to treat some protozoal diseases, such as malaria. It is a common topical treatment for acne and can be useful against some methicillin-resistant Staphylococcus aureus infections. The veterinary uses of clindamycin are quite similar to its human indications, and include treatment of osteomyelitis, skin infections, and toxoplasmosis, for which it is the preferred drug in dogs and cats.

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Acacia gum

We are manufacturer supplier of arabic gum in various forms like
 
Kibbled
Mechanical Powder
Spray Dried Powder
 
Our available grades are suitable to be used in industries right from Food and Beverages, Cosmetics and Pharma, Confectionery, Non-Food industries.
 
For more details please contact us.

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Cyclosporine

Cyclosporine is a cyclic undecapeptide from an extract of soil fungi. It is a powerful immunosupressant with a specific action on T-lymphocytes. It is used for the prophylaxis of graft rejection in organ and tissue transplantation.Cyclosporine binds to cyclophillin. The complex then inhibits calcineurin which is normally responsible for activating transcription of interleukin 2. Cyclosporine also inhibits lymphokine production and interleukin release. Cyclosporine emulsion is thought to act as a partial immunomodulator in patients whose tear production is presumed to be suppressed due to ocular inflammation associated with keratoconjunctivitis sicca.

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Isotretinoin

Isotretinoin is a medication used for the treatment of severe acne. It is sometimes used in prevention of certain skin cancers.Isotretinoin noticeably reduces the production of sebum and shrinks the sebaceous glands. It stabilises keratinization and prevents comedones from forming. It also reduces inflammation in moderate-severe inflammatory acne.

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