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4-Hydroxynonenal is an α,β-unsaturated hydroxyalkenal which is produced by lipid peroxidation in cells. It is the primary alpha,beta-unsaturated hydroxyalkenal formed in this process. It is found throughout animal tissues, and in higher quantities during oxidative stress due to the increase in the lipid peroxidation chain reaction, due to the increase in stress events. It has been hypothesized by several researchers to play a key role in cell signal transduction, in a variety of pathways from cell cycle events to cellular adhesion.

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4-Hydroxyphenylpyruvic Acid

4-Hydroxyphenylpyruvic acid is an intermediate in the metabolism of phenylalanine.

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