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Scopoletin is a coumarin found in the root of plants in the genus Scopolia. It can also be found in some whiskies or in dandelion coffee.

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Scoulerine is an alkaloid found in the Opium poppy, Croton flavens, and certain plants in the Erythrina genus. Studies show that scoulerine is an antagonist at the α2-adrenoceptor, α1D-adrenoceptor and 5-HT receptor. It has also been found to be a GABAA receptor agonist.

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