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DDT was the first of the chlorinated insecticides, it was originally prepared in 1873. The use of DDT increased enormously after WW II because of its effectivenessagainst mosquitoes and lice. DDT and it’s main metabolite DDE, have been found to be toxic to animals, cause birth defects and it’s known to be an endocrine disruptor (EDC). The use of DDT has been banned in the US since 1973, although it’s still used in other parts of the world.

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DDT (from its trivial name, dichlorodiphenyltrichloroethane) is one of the most well-known synthetic pesticides. It is a chemical with a long, unique, and controversial history.First synthesized in 1874, DDT's insecticidal properties were not discovered until 1939, and it was used with great success in the second half of World War II to control malaria and typhus among civilians and troops. The Swiss chemist Paul Hermann Müller was awarded the Nobel Prize in Physiology or Medicine in 1948 "for his discovery of the high efficiency of DDT as a contact poison against several arthropods."[2] After the war, DDT was used as an agricultural insecticide, and soon its production and use skyrocketed.

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o-Chlorobenzoylcyclopentane is used as a reagent in the preparation of bicyclic and polycyclic aromatic hydrocarbons.

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