Ophthalmology Drugs used in eye diseases treatment

Ophthalmology-and-Otorhinolaryngology-agents

Acacia gum

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Acetazolamide

Acetazolamide is a carbonic anhydrase inhibitor. It used to treat glaucoma, epileptic seizures, Idiopathic intracranial hypertension (pseudotumor cerebri), altitude sickness, cystinuria, and dural ectasia. Acetazolamide is available as a generic drug and is also a diuretic.

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Azelastine Hydrochloride

Azelastine Hydrochloride is an Histamine H1 Receptor (H1-receptor) antagonist, with antiallergic effects related to histamine antagonism, and further antiallergic and antiinflammatory effects unrelated to H1-receptor binding. It is an activator of NF κB.

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Bepotastine Besilate

Bepotastine Besilate is a selective histamine1-receptor antagonist and mast cell stabilizer with inhibitory effects on eosinophilic activity. It is used to treat itching of the eye caused by a condition known as allergic conjunctivitis. It works by preventing the effects of certain inflammatory substances, which are produced by cells in your eyes and sometimes cause allergic reactions.

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Betamethasone

Betamethasone is a potent glucocorticoid steroid with anti-inflammatory and immunosuppressive properties. Its lack of mineralocorticoid properties makes betamethasone particularly suitable for treating cerebral edema and congenital adrenal hyperplasia. Betamethasone is a corticosteroid used as a topical cream to relieve skin irritation, such as itching and flaking from eczema. It is used as a treatment for local psoriasis, as Betamethasone dipropionate and salicylic acid, or as the combination betamethasone/calcipotriol. Betamethasone sodium phosphate is sometimes prescribed as an intramuscular injection (I.M) for itching from various ailments including allergic reactions to poison ivy and similar plants.

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Betaxolo Hydrochloride

Betaxolo Hydrochloride is a β-adrenergic blocking agent used primarily in the treatment of raised intra-ocular pressure, open-angle glaucoma, ocular hypertension, pseudo-exfoliative glaucoma and closed-angle glaucoma. Betaxolol hydrochloride is used in conditions such as ocular hypertension or open-angle glaucoma where there is increased pressure inside the eye. It works by reducing the amount of fluid that is produced inside the eye. This leads to a reduction in pressure inside the eye. It may be used alone or in combination with other intraocular pressure lowering medications.

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Bicuculline

Bicuculline is a light-sensitive competitive antagonist of GABAA receptors. It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and several Corydalis species.Bicuculline is also a pharmcological agent that, when used, increases the frequency of occurrence of ocular saccades during visual fixation.

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Bimatoprost

Bimatoprost is a prostaglandin analog/prodrug used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. It reduces intraocular pressure (IOP) by increasing the outflow of aqueous fluid from the eyes. Bimatoprost eye drop may contain a preservative known as benzalkonium chloride.

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Brimonidine D-Tartrate

Brimonidine D-Tartrate is a relatively selective α-2 adrenergic agonist for ophthalmic use.It is a prescription eye drop. It is approved to treat high eye pressure in people with open-angle glaucoma or ocular hypertension. It has a peak ocular hypotensive effect occurring at two hours post-dosing. It binds to and activates alpha receptors in the eye, causing two important effects. It decreases the amount of fluid (known as aqueous humor) produced by the eye and increases the rate of drainage.

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Chloramphenicol

Chloramphenicol is a bacteriostatic antimicrobial. It is considered a prototypical broad-spectrum antibiotic, alongside the tetracyclines.It is effective against a wide variety of Gram-positive and Gram-negative bacteria, including most anaerobic organisms. It has a relatively simple structure and was the first broad-spectrum antibiotic to be discovered. It acts by interfering with bacterial protein synthesis and is mainly bacteriostatic.Chloramphenicol is used in treatment of cholera, as it destroys the vibrios and decreases the diarrhea. It is effective against tetracycline-resistant vibrios. It is also used in eye drops or ointment to treat bacterial conjunctivitis.

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