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Tanomastat

Tanomastat is a protease inhibitor.

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Tapentadol

Tapentadol is a centrally-acting analgesic with a dual mode of action as an agonist at the μ-opioid receptor and as a norepinephrine reuptake inhibitor. It is a new molecular entity that is structurally similar to tramadol. It has opioid and nonopioid acitivity in a single compound. Tapentadol is FDA approved for the treatment of moderate to severe acute pain. Due to the dual mechanism of action as an opioid agonist and norepinephrine reuptake inhibitor, there is potential for off label use in chronic pain. Its dual mode of action provides analgesia at similar levels of more potent narcotic analgesics such as hydrocodone, oxycodone, and meperidine with a more tolerable side effect profile.

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Taranabant

Taranabant is a cannabinoid receptor type 1 inverse agonist being investigated as a potential treatment for obesity due to its anorectic effects. It was discovered by Merck & Co. In October 2008, Merck has stopped its phase III clinical trials with the drugs due to high level of central side effects, mainly depression and anxiety.

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Tasimelteon

Tasimelteon is a drug approved by the U.S. Food and Drug Administration for the treatment of non-24-hour sleep-wake disorder. Tasimelteon is a selective agonist for the melatonin receptors MT1 and MT2.Tasimelteon (previously known as BMS-214,778) was developed for the treatment of insomnia and other sleep disorders.

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Tasimelteon LAB GRADE 97%

Tasimelteon (trade name Hetlioz) is a drug approved by the FDA solely for the treatment of non-24-hour sleep–wake disorder (often designated as N24HSWD) in totally blind adults. It is a selective agonist for the melatonin receptors MT1 and MT2 in the suprachiasmatic nucleus of the brain, similar to other members of the melatonin receptor agonist class of which ramelteon (2005) and agomelatine (2009) were the first approved.

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Taxifolin

Taxifolin is a flavanonol, a type of flavonoid. It can be found in the açaí palm, in the Siberian larch and in the silymarin extract from the milk thistle seeds. It is also found in small quantities in red onion. It acts as a potential chemopreventive agent by regulating genes via an ARE-dependent mechanism. It has shown to inhibit the ovarian cancer cell growth in a dose-dependent manner. The capacity of taxifolin to stimulate fibril formation and promote stabilization of fibrillar forms of collagen can be used in medicine. Also taxifolin inhibited the cellular melanogenesis as effectively as arbutin, one of the most widely used hypopigmenting agents in cosmetics.

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Tebanicline

Tebanicline is a drug which acts as a partial agonist at neuronal nicotinic acetylcholine receptors, binding to both the α3β4 and the α4β2 subtypes.

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Teclozan

Teclozan is an antiprotozoal agent. It is a dichloroacetamide.

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Tegaserod Maleate

Tegaserod is a 5-HT4 agonist and used for the management of irritable bowel syndrome and constipation.

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Telcagepant

Telcagepant is an investigational drug for the acute treatment and prevention of migraine. In the acute treatment of migraine, it was found to have equal potency to rizatriptan and zolmitriptan in two Phase III clinical trials.

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