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Sarms Powder Steroids Pirfenidone 53179-13-8 Anti Fibrosis

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Sarms Powder Steroids Pirfenidone 53179-13-8 Anti Fibrosis 
 
Pirfenidone Basic information
 
Product Name: Pirfenidone
Synonyms: 5-methyl-1-phenyl-2(1h)-pyridon;amr-69;PIRFENIDONE;5-METHYL-1-PHENYL-1H-PYRIDIN-2-ONE;5-METHYL-1-PHENYL-2(1H)-PYRIDINONE;5-METHYL-1-PHENYL-2-(1H)-PYRIDONE;5-Methyl-N-phenyl-2-1H-pyridone;Pirfenidone also see 5-Methyl-1-Phenyl-2(1H)-Pyridinone
CAS: 53179-13-8
MF: C12H11NO
MW: 185.22
EINECS: N/A
Melting point: 96-97°C
Storage temp.: Store at RT
Solubility: DMSO: ≥10 mg/mL, Soluble
Chemical Properties: Off-White Solid
Usage: Pirfenidone has demonstrated activity in multiple fibrotic conditions, including those of the lung, kidney and liver
Product Categories: Aromatics Compounds;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Cytokine signaling;Inhibitors.
 
Pirfenidone Description:
 
Pirfenidone (INN, BAN) is an anti-fibrotic drug for the treatment of idiopathic pulmonary fibrosis (IPF). It works by reducing lung fibrosis through downregulation of the production of growth factors and procollagens I and II.
 
It is a drug developed by several companies worldwide, including InterMune Inc. (now part of Roche), Shionogi Ltd., and GNI Group Ltd. In 2008, it was first approved in Japan for the treatment of IPF after clinical trials, under the trade name of Pirespa by Shionogi & Co. In October 2010, the Indian Company Cipla launched it as Pirfenex. In 2011, it was approved for use in Europe for IPF; it was approved in Canada in 2012 ; and was approved in the United States in October 2014 under the same name. In September 2011, the Chinese State Food and Drug Administration provided GNI Group Ltd with new drug approval of pirfenidone in China, and later manufacture approval in 2013 under the trade name of Etuary.
 
In 2014 it was approved in Mexico under the name KitosCell LP, indicated for pulmonary fibrosis and liver fibrosis.There is also a topical form created for the treatment of abnormal wound healing processes.
 
Pirfenidone Application:
 
In vitro, pirfenidone can inhibit the uterine flesh tumour cells and leiomyoma cells proliferation. Pirfenidone can inhibit the TGF - beta - 1 inducing fibroblast collagen formation. Inhibition of PDGF, FGF and TGF - beta - 1 inducing fibroblast proliferation. In hamster model, pirfenidone, taken by mouth, that can the prevention and treatment of pulmonary fibrosis . Pirfenidone can prevent the sclerosing peritonitis in rats induced by chemical, can also be keloid grafting for the treatment of nude mice. Pirfenidone 0.01 1 mg/ml can suppress the matrix and dose dependent manner serum stimulate uterine fibroids and leiomyoma cell DNA synthesis, the compound has no cytotoxic effect, has no effect on collagen mRNA level also. Pirfenidone in hamster pulmonary fibrosis model can reduce the disease before the collagen I mRNA level enhancement, reduce the level of the lung hydroxyproline and malondialadehyde and lung preserved ammonia acyl hydroxylase activity.
 

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ethyl (1R,4S,6S)-7-oxabicyclo[4.1.0]heptane-4-carboxylate 99%

Shanghai Ansion Pharma Technology Co.,Ltd

www.ansionpharma.com

ann.xu@ansionpharma.com

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4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol 99%

Ansion pharma is a factory providing pharmaceutical intermediate and custom synthesis service. 
 
More products infomation, pls contact us: ann.xu@ansionpharma.com; www.ansionpharma.com

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4-(3-chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol 99%

Ansion pharma is a factory providing pharmaceutical intermediate and custom synthesis service. 
 
More products infomation, pls contact us: ann.xu@ansionpharma.com; www.ansionpharma.com

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4-(4-bromo-3-((methoxymethoxy)methyl)phenoxy)benzonitrile 99%

Ansion pharma is a factory providing pharmaceutical intermediate and custom synthesis service. 
 
More products infomation, pls contact us: ann.xu@ansionpharma.com; www.ansionpharma.com

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7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one 99%

Ansion pharma is a factory providing pharmaceutical intermediate and custom synthesis service. 
 
More products infomation, pls contact us: ann.xu@ansionpharma.com; www.ansionpharma.com

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Global Hot Sell Anti Aging Coenzyme Q10 / Ubiquinol 303-98-0

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Global Hot Sell Anti Aging Coenzyme Q10 / Ubiquinol 303-98-0

Coenzyme Q10 Basic Info.:

Product Name: Coenzyme Q10

Synonyms: LABOTEST-BB LT00244787;COQ10;COENZYME Q10;Q-10;Q10 COENZYME;UBIDECARENONE;UBIQUINONE;UBIQUINONE-10 

CAS: 303-98-0 

MF: C59H90O4 

MW: 863.34 

EINECS: 206-147-9 

Chemical Properties Yellow-Orange Crystalline Powder 

Usage antioxidant, cardiovascular agent 

Usage Antibacterial and antioxidant for preventing and treating cancer. 

Usage Antibacterial, antioxidant 

Biological Activity Component of the mitochondrial transporter chain that behaves as a powerful antioxidant. Displays neuroprotective activity.

Ubidecarenone Details Of Coenzyme Q10:

Coenzyme Q10 (CoQ10 or ubiquinone) has a low risk of side effects and it is an essential vitamin-like substance with many health benefits. 

It is proven helpful in treating heart-related problems such as congestive heart failure and to lower high blood pressure. 

Coenzyme Q10 is a quinone, which is a substance that helps provide energy to cells in all oxygen-breathing organisms. Researchers first discovered coenzyme Q10 in 1957, and first named it ubiquinone, 

Because it was a quinone that was found in every cell of the body (the prefix ubi means everywhere). 

Later studies showed that ubiquinone acts as a coenzyme in the body, without which the three enzymes that provide energy to the body cannot function. 

Coenzyme Q10 Benefits: 

1. Anti-Aging As a strong antioxidant Q10 protects cells from chemicals and other harmful factors. 

2. Anti-oxidant Q10 naturally prevents our body and cells from free radicals damage and works as a shield against harmful effects. 

3. Muscles are also in need of this enzyme, due to its energy boosting quality. Experiments proved that people who had a balanced Q10 level were more energetic and vigorous 

4. Heart-related problems It is proven helpful in treating heart-related problems such as congestive heart failure and to lower high blood pressure. 

5. Improves immunity and can dramatically slow tumor growth. 

Coenzyme Q10 Application: 

1. Applied in pharmaceutical field, it can be used for treating cardiovascular disease. 

2. Applied in Cosmetics, it can be sued for skin whitening, removing wrinkling and slowing down ageing. 

 

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High Purity Dutasteride Avodart For Bodybuilding 164656-23-9

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Plant Extract Whitening Cosmetic Arbutin Arbutoside 497-76-7

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Plant Extract Whitening Cosmetic Arbutin Arbutoside 497-76-7
 
Arbutin Basic information
 
Product Name: Arbutin
Synonyms: 4-hydroxyphenyl-beta-d-glucopyranosid; Arbutin; Arbutoside
CAS: 497-76-7
MF: C12H16O7
MW: 272.25
EINECS: 207-850-3
Melting point: 195-198 °C
Alpha: -64 º (c=3)
Refractive index: -65.5 ° (C=4, H2O)
Storage temp.: 2-8°C
Solubility: H2O: 50 mg/mL hot, clear
Water Solubility: 10-15 g/100 mL at 20 ºC
Sensitive: Hygroscopic
Merck: 14,773
BRN : 89673
Stability: Stable. Hygroscopic - store under dry nitrogen.
Chemical Properties: Crystalline powder
Uses: Diuretic and anti-infective drugs of urinary system. Color photographic developing stabilizer. Whitening, anti-freckle, hair care in cosmetics.
Product Categories: Biochemistry;Glucose;Glycosides;Sugars;Natural Plant Extract;Herb extract;chemical reagent;pharmaceutical intermediate;phytochemical;standardized herbal extract;Uva, Ursi, p-Arbutin, Hydroquinone β-D-glucopyranoside;natural product;Inhibitors.
 
Product Description:
 
Alpha-Arbutin is a synthetic compound derived from natural plant sources. It is a water-soluble, white powder that remains stable in a pH range between 3.5 to 6.5. According to Lotion Crafters, a company offering skin care products, a 1 percent solution in clinical tests resulted in faster and better skin lightening after testing against other products for one month. Epidermal melanin biosynthesis, the effects of melanin on the skin, is blocked by Alpha-Arbutin; it reportedly works best when used for a period of two to three months.
 
Application:
 
1. Cosmetic industry:
Alpha Arbutin protect the skin against damage caused by free radicals Alpha Arbutin is a skin whitening agent which is very popular in Japan and Asian countries for skin de-pigmentation, Alpha Arbutin inhibits the formation of melanin pigment by inhibiting Tyrosinase activity. Alpha Arbutin is very safe skin agent for external use which does not have toxicity, stimulation, unpleasant odor or side effect such as Hydroqinone.The encapsulation of Alpha Arbutin constitute a delivery system to potentialize the effect in time.
 
2. Medical industry:
Back in the 18th century, Alpha Arbutin was first used in medical areas as an anti-inflammatory and antibacterial agent. Alpha Arbutin was used particularly for cystitis, urethritis and pyelitis. These uses still until today where natural medicine uses only natural ingredients to treat any disease. Also Alpha Arbutin may be used to repress the virulence of bacterial pathogens and to prevent contaminating bacteria, Alpha Arbutin is also used for treating allergic inflammation of the skin.
 
Function :
 
1.Alpha arbutin will relieve and dispell chloasma, melanin, acne ect;
2. Alpha arbutin has good effects of sterilization and relieving cough;
3. It used to alleviate pain of burn and scald,enhancing immune fuction;
4.It can promote skin elasticity, retaining skin moisture and slowing down aging skin;
5.It has function of restraining the activity of tyrosinase; preventing the formation of melanin.
 

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Raw Medical Material Powder Priligy / Dapoxetine 119356-77-3

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Raw Medical Material Powder Priligy / Dapoxetine 119356-77-3
 
Dapoxetine Basic Info:
 
Product Name: Dapoxetine 
Synonyms: Priligy;Dapoxetine;Dapoxetine hydrochloride;Dapoxetine base;D-Dapoxetine HCL
CAS: 119356-77-3
MF: C21H23NO.ClH
MW: 341.88
EINECS: N/A
Purity: 99%
Appearance: White powder, odorless, slightly sweet, soluble in water and alcohol.
Product Categories: Erectile Dysfunction;API;Dapoxetine hydrochloride
  
Dapoxetine Description:
 
Premature ejaculation (PE) is the most common male sexual dysfunction. Dapoxetine hydrochloride, belonging to a class of drugs known as selective serotonin reuptake inhibitors or, was the first drug originally approved for the on-demand treatment of men with PE. We aimed to compare the intravaginal ejaculatory latency time (IELT), patient-reported global impression of change (PGIC), and adverse effect (AE) incidence associated with the use of dapoxetine (30 mg and 60 mg) versus placebo, and evaluate the differences in administering 60 mg versus 30 mg as on-demand medical oral therapy for the treatment of PE via a literature review and meta-analysis. Relevant randomized controlled trials (RCTs) were identified from PubMed, EMBASE, and Cochrane Central Register of Controlled Trials (Cochrane Library) databases. Ultimately, a total of seven RCTs with 8039 patients were included. Our meta-analysis demonstrated that dapoxetine (in the 30 mg and 60 mg subgroup) resulted in significantly higher IELT, PGIC, and AE incidence relative to the placebo, with higher proportions observed for 60 mg versus 30 mg of dapoxetine administration. The most common AEs were mild and tolerable. We conclude that dapoxetine (particularly the 60 mg dosage) may be considered a safe and effective drug for patients with PE.
 
Dapoxetine Application:
 
Dapoxetine hydrochloride is a drug that is used to treat premature ejaculation in men. It is available by prescription and is taken orally, prior to sexual intercourse. The drug belongs to the class called serotonin reuptake inhibitors (SSRIs), which have mainly been used to treat depression.
 
Sexual dysfunction, including premature ejaculation, is an extremely common condition worldwide. The cause of premature ejaculation has not been fully elucidated, but may include both psychological and physiological factors. Premature ejaculation refers to a short ejaculation time, which can affect the satisfaction of both partners during sexual intercourse.
 

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