chemical-categories

 

Beauty Cosmetic Peptide Snap-8 Acetyl Glutamyl Heptapeptide-3 868844-74-0

 

Snap-8 Basic Info.:

 

Product Name: Snap-8 (Acetyl Glutamyl Heptapeptide-3)

Synonyms: SNAP-8;Acetyl GlutaMyl Heptapeptide-3;Acetyl GlutaMyl Octapeptide-3;Acetyl Octapeptide-3;Acetyl Octapetpide-3;Acetyl Octapeptide-8.

CAS: 868844-74-0

MF: C41H70N16O16S

MW: 1075.16

Product Categories: Cosmetics beauty peptide

Density: 1.56

Usage: anti-wrikle

 

SNAP-8 Application:

 

The synthesis of SNAP-8 involves a final freeze-drying step. Freeze-dried products are commonly obtained as a polymorphous crystalline powder, which means that locally some aggregates and differences in crystal size may appear. This polymorphism is not associated to chemical differences and extensive work performed by the analytical department has ensured the homogeneity of the product. SNAP-8 is presented either as SNAP-8 Powder, an octapeptide in powder form which can be easily dissolved in water, or as SNAP-8 Solution, an aqueous solution containing 0.5 g/L of the powder version. It can be incorporated at the final stage of the manufacturing product, provided the temperature is below 40 degrees Celsius. Taking into consideration the concentration of peptide in SNAP-8 Solution, it is recommended that 3 to 10% of the solution is present in the final formulation in order to obtain significant anti-wrinkle activity.

 

SNAP-8 is a mimic of the N-terminal end of SNAP-25 which competes with SNAP-25 for a position in the SNARE complex, thereby modulating its formation. If the SNARE complex is slightly destabilized, the vesicle can not release neurotransmitters efficiently and therefore muscle contraction is attenuated, preventing the formation of lines and wrinkles

 

The Benefits of SNAP-8:

 

- Reduces the depth of wrinkles on the face caused by the contraction of muscles of facial expression, especially in the forehead and around the eyes.

- A safer, cheaper, and milder alternative to Botulinum Toxin, topically targeting the same wrinkle-formation mechanism in a very different way.

- Has been incorporated in cosmetic formulations such as emulsions, gels, sera, etc., where removal of the deep lines or wrinkles in the forehead or around the eyes area is desired.

 

SNAP-8 Solution:

 

INCI name: Water, Acetyl Glutamyl Heptapeptide-1 

Appearance: Transparent solution

Contents: 0.05 % SNAP-8 Powder 

Preservative: 0.3 % Phenonip

 

SNAP-8 Storage And Shelf Life:

 

SNAP-8 Powder and SNAP-8 Solution must be kept in a cool, dark and clean place to ensure a shelf life of at least twelve months. For long term storage it is recommended to store both forms at 4 ºC which extends shelf life to at least eighteen months. In rare cases, refrigerated storage of SNAP-8 Solution can cause precipitation of the preservative. This does not affect the integrity of the product.

 

 

High Purity Estrogen Raw Female Steroid Powders Ethynyl Estradiol 57-63-6

 

Ethynyl Estradiol Basic Info.:

 

Ethynyl estradiol Basic information

Product Name: Ethynyl estradiol

CAS: 57-63-6

MF: C20H24O2

MW: 296.4

EINECS: 200-342-2

Chemical Properties: Off-White to Light-Yellow Crystalline Powder

Usage: A metabolite of 17A-Ethynylestradiol

Usage: A synthetic steroid with high oral estrogenic potency

Usage estrogen, plus progestogen as oral contraceptive

Standard: USP28

 

Ethynyl Estradiol Description:

 

Ethinylestradiol is a man-made form of the naturally occurring female hormone called oestrogen.

It is prescribed to treat period (menstrual) problems, and also to help ease menopausal symptoms. It is usually prescribed alongside another female hormone called a progestogen.

 

Ethinyl estradiol also sometimes written as ethinylestradiol, ethynyl estradiol, or ethinyl? Stradiol, is a derivative of 17β -estradiol (E2), the major endogenous estrogen in humans. EE is an orally bioactive estrogen used in many formulations of combined oral contraceptive pills. It is one of the most commonly used medications for this purpose.

 

Estinyl was a preparation of EE alone that was used for the management of menopausal symptoms and female hypogonadism.

EE is released into the environment as a xenoestrogen from the urine and feces of people who take it as a medication.

 

Ethynyl Estradiol Application:

 

When estrogen is prescribed for a woman with a uterus, progestin should also be initiated to reduce the risk of endometrial cancer. A woman without a uterus does not need progestin. Use of estrogen, alone or in combination with a progestin, should be with the lowest effective dose and for the shortest duration consistent with treatment goals and risks for the individual woman. Patients should be reevaluated periodically as clinically appropriate (e.g., 3-month to 6-month intervals) to determine if treatment is still necessary. For women who have a uterus, adequate diagnostic measures, such as endometrial sampling, when indicated, should be undertaken to rule out malignancy in cases of undiagnosed persistent or recurring abnormal vaginal bleeding.

Short-term cyclic use for treatment of moderate to severe vasomotor symptoms, vulval and vaginal atrophy associated with the menopause, the lowest dose and regimen that will control symptoms should be chosen and medication should be discontinued as promptly as possible.

Attempts to discontinue or taper medication should be made at 3- to 6-month intervals. The usual dosage range is 1 to 5 mg injected every 3 to 4 weeks.

For treatment of female hypoestrogenism due to hypogonadism 1.5 to 2 mg injected at monthly intervals.

 

 

Muscle Supplements Norandrostenolone Nandrolone For Bodybuilding 434-22-0

 

Nandrolone Basic Info.

 

Product Name: Nandrolone

Other name: Nandrolon; Norandrostenolone; Nortestosterone

CAS No: 434-22-0

Molecular Formula: C18H26O2

Molecular Weight: 274.4

Einecs No: 207-101-0

Purity: 99%

Appearance: White powder.

Usage:can be used as pharmaceutical material

 

Nandrolone Description:

 

Nandrolone base is usually synthesized from the male reproduction hormone testosterone. It can help rebuild body tissue, increase body and bone mass and encourage the formation of red blood cells. It also can make muscle growth, appetite stimulation and increase red blood cell production and bone density. Clinical studies have shown it to be effective in treating anaemia, osteoporosis and some forms of neoplasia including breast cancer, and also acts as a progestin-based contraceptive. Nandrolone is most commonly sold commercially as its decanoate ester (Deca-Durabolin) and less commonly as a phenylpropionate ester (Durabolin).

 

Nandrolone Applications:

 

Nandrolone is an anabolic steroid which are a group of drugs that are usually synthesized from the male reproduction hormone testosterone , and it can helps to rebuild body tissue, increase body and bone mass and encourage the formation of red blood cells.

 

The positive effects of the drug include muscle growth, appetite stimulation and increased red blood cell production and bone density. Clinical studies have shown it to be effective in treating anaemia, osteoporosis and some forms of neoplasia including breast cancer, and also acts as a progestin-based contraceptive.

 

Nandrolone is most commonly sold commercially as its decanoate ester (Deca-Durabolin) and less commonly as a phenylpropionate ester (Durabolin).

 

 

1,4-Androstadienedione Male Sex Enhancement For Cancer Treatment 897-06-3 

 

1,4-Androstadienedione Basic Infor.

 

Product Name: Androsta-1,4-diene-3,17-dione

Synonyms: Delta-1,4-Androstadiene-3,17-Dione;Androstadiendione;Androstadienedione;Androsta-1,4-Diene-3,17-Dione;1-Dehydroandrostenedione;1,4-Androstadien-3,17-Dione;1,4-Androstadiene-3,17-Dione

CAS: 897-06-3

MF: C19H24O2

MW: 284.39

EINECS: 212-977-2

Melting point: 138-139 °C(lit.)

Storage temp.: Refrigerator

Chemical Properties: White Crystalline Powder

Usage: Boldenone related steroid; anabolic androgenic steroid

Product Categories: Pharmaceutical Intermediates;Intermediates & Fine Chemicals;Pharmaceuticals;Steroids

 

1,4-Androstadienedione Description:

 

Androsta-1 is used for simplified hormone drugs, from the testis or urine extracted with the role of a male hormone steroid, norethisterone, testosterone propionate in the middle body, is widely used in small rheumatoid arthritis, diuretic, and a variety of contraceptive to control infectious inflammation.

Androsta-1 is the precursor to bolde-none, and as of January 4, 2010 is a Schedule III Controlled Substance. In 2004 the United States Congress passed the Anabolic Steroid Control Act of 2005 which placed 36 steroids and over the counter pro-hormones into schedule III of the Controlled Substances Act. 

 

1,4-Androstadienedione Application:

 

Simplified hormonal drugs, from the testis or urine extracted with the role of a male hormone steroids, norethisteron.Bol-dione is the precursor to bolde-none, and as of January 4, 2010 is a Schedule III Controlled Substance.In 2004 the United States Congress passed the Anabolic Steroid Control Act of 2005 which placed 36 steroids and over the counter pro-hormones into schedule III of the Controlled Substances Act. In this legislation bolde-none was classified as a controlled substance and bol-dione remained legal.In April 2008 the United States Drug Enforcement Administration published an "Initial Notice of Proposed Rulemaking" concerning the scheduling of three anabolic substances: bol-dione, desoxymethyltestos-terone, and diene-dione. In 2008, at the time of the proposal, these three substances were listed as ingredients in more than 58 dietary supplements which were available for purchase over the counter.

 

 

99% Male Enhancement Drug Raw Material Powder Tadalafil Cialis 171596-29-5

 

Tadalafil Basic Info:

 

Product Name: Tadalafil

Synonyms: Tadalafil;Cialis;IC 351;Cialis IC35

CAS: 171596-29-5

MF: C22H19N3O4

MW: 389.4

EINECS: 200-835-2

Assay: 99.5%min

Appearance: off-white crystalline

Product Categories: Active Pharmaceutical Ingredients;Cnbio;Erectile Dysfunction;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;API's;Steroid and Hormone;Inhibitor;API;Tadalafil;NUCYNTA;Pyridines ,Halogenated Heterocycles 

Usage: an oral drug that is used for treating impotence (the inability to attain or maintain a penile erection) and benign prostatic hyperplasia (BPH)

 

Tadalafil Description:

 

Cialis (Tadalifil), a phosphodiesterase type 5 inhibitor, is used to treat erectile dysfunction (ED) and decreased libido in males. Cialis works by aiding relaxation of blood vessels and increasing blood flow in the penis during sexual arousal, resulting in improved erectile function.

Tadalafil is used for Erectile dysfunction and pulmonary hypertension, the rapid absorption after oral administration, 2 hours to reach maximum observed plasma concentrations of average time after administration of (Cmax). Influence of absorption rate and degree is not affected by food tadalafil, so it can be with or without with clothes and food.

 

Tadalafil is an oral drug for the treatment of ED, used in the treatment of erectile dysfunction and premature ejaculation, erectile function impairment and premature ejaculation has very significant improvements. There are over 1500 documents to prove the caused by different causes impotence premature ejaculation, knew the success rate is above 80%, and show its reliable curative effect, through the use of more than 20 million people worldwide, proved its long-term stability, the safety of 25 to 60 minutes of work function to coincide with a time needed for foreplay, knew the time adjustment in the highest drug concentration time, help both husband and wife a satisfactory sex life.

 

Tadalafil Application:

 

Since people who have taken tadalafil within the past 48 hours cannot take organic nitrates to relieve angina (such as glyceryl trinitrate spray), these patients should seek immediate medical attention if they experience anginal chest pain.In the event of a medical emergency, paramedics and medical personnel should be notified of any recent doses of tadalafil.

 

Tadalafil is metabolized predominantly by the hepatic CYP3A4 enzyme system. The presence of other drugs which induce this system can shorten tadalafil half-life and reduce serum levels, and hence efficacy, of the drug.

 

Tadalafil has been used in approximately 15,000 men participating in clinical trials, and over eight million men worldwide (primarily in the post-approval/post-marketing setting). The most common side effects when using tadalafil are headache, stomach discomfort or pain, indigestion, burping, acid reflux, back pain, muscle aches, flushing, and stuffy or runny nose. These side effects reflect the ability of PDE5 inhibition to cause vasodilation (cause blood vessels to widen), and usually go away after a few hours. Back pain and muscle aches can occur 12 to 24 hours after taking the drug, and the symptom usually disappears after 48 hours.

 

 

99.9% Pramoxine Hydrochloride Anesthetic Anodye CAS 637-58-1 Pramoxine HCl

 

Pramoxine HCL Basic Info.:

 

Product Name: Pramoxine Hydrochloride

CAS: 637-58-1

EINECS number: 211-293-1

Molecular formula: C17H28ClNO3

Molecular Weight: 329.8621

Boiling point: 427 °C at 760 mmHg

Flash Point: 123.5 °C

Vapor Pressure: 1.7E-07mmHg at 25 °C

Appearance: White or almost white crystalline powder

 

Pramoxine HCL Description:

 

Pharmacologic study revealed it to be potent and of low acute and subacute toxicity, well tolerated by most mucous membranes and of a low sensitizing index in man. Like other local anesthetics, paramoxine decreases the permeability of neuronal membranes to sodium ions, blocking both initiation and conduction of nerve impulses. Depolarization and repolarization of excitable neural membranes is thus inhibited, leading to numbness.

 

Pramoxine HCL Applications:

 

Topical anesthetics are used to relieve pain and itching caused by conditions such as sunburn or other minor burns, insect bites or stings, poison ivy, poison oak, poison sumac, and minor cuts and scratches. Pramocaine and dibucaine are also common ingredients in over the counter hemorrhoid preparations.

 

 

Anabolic Raw Steroid Powder Trenbolone Base For Muscle Building 10161-33-8

 

Trenbolone Base Basic Info.

 

Product name: Trenbolone

Alias: Trenbolone;RU2341;Trienbolone;b-Trenbolone;

CAS: 10161-33-8

MF: C18H22O2

MW: 270.37

Assay: 99%

Melting point: 170°C

Storage temp.: 2-8°C

Appearance: Light yellow crystal powder

Product Categories: Steroids;Intermediates & Fine Chemicals;Pharmaceuticals;Steroid and Hormone;Finished Steroid and Hormone;trenbolone series

Usage: It can be used for muscle building. Trenbolone is literally the most powerful anabolic steroid conventionally and commercially available. Trenbolone is an extremely powerful, impressive, and versatile anabolic steroid that tends to suffer from a heavy shroud of rumor, misunderstanding, and mysticism.

 

Trenbolone Base Description:

 

Trenbolone is essentially a derivative of Nandrolone with some very significant differences in its chemical properties and strength. Trenbolone and its parent hormone Nandrolone both belong to a class/category of anabolic steroids known as 19-nor compounds, or 19-nors (short for 19-nortestosterone). 19-nor anabolic steroids are labeled as such because they lack the 19th carbon on their structure - this carbon exists on Testosterone and all other anabolic steroids with the exception of 19-nor compounds, such as Nandrolone and Trenbolone.

 

Trenbolone is also much more potent than testosterone at suppressing endogenous androgen production. This makes clear the fact that estrogen is not the only culprit with negative feedback inhibition, as here there is no buildup of this hormone to report here. There is however some activity as a progestin inherent in this compound, as trenbolone is a 19-nortestosterone (nandrolone) derivative (a trait characteristic of these compounds).

 

 

Dapoxetine Hydrochloride Sex Enhancement Powder Dapoxetine HCl 129938-20-1

 

Dapoxetine HCL Basic Info:

 

Product Name: Dapoxetine HCL

Synonyms: Dapoxetine HCL; Dapoxetine Hydrochloride; Rimonabant 75000; LY-21044

Alias: Priligy; Dapoxetine Hydrochloride

CAS No: 129938-20-1

MF: C9H7ClN2O5

MW: 258.62

Purity: 99%

Melting point: 175-179°C

Storage temp.: -20°C Freezer

Appearance: Off-white Cryst, odorless, slightly sweet, soluble in water and alcohol.

Usage:

(1)Dapoxetine hydrochloride is a short-acting novel selective serotonin reuptake inhibitor marketed for the treatment of premature ejaculation in men. Premature ejaculation (PE) is the most common male sexual disorder, estimated to affect up to 30% of men. D

(2)Selective serotonin reuptake inhibitor (SSRI)

Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals;Amines;Aromatics;Inhibitors;Dapoxetine Hydrochloride

 

Dapoxetine HCL Description:

 

Premature ejaculation (PE) is the most common male sexual dysfunction. Dapoxetine hydrochloride, belonging to a class of drugs known as selective serotonin reuptake inhibitors or, was the first drug originally approved for the on-demand treatment of men with PE. We aimed to compare the intravaginal ejaculatory latency time (IELT), patient-reported global impression of change (PGIC), and adverse effect (AE) incidence associated with the use of dapoxetine (30 mg and 60 mg) versus placebo, and evaluate the differences in administering 60 mg versus 30 mg as on-demand medical oral therapy for the treatment of PE via a literature review and meta-analysis. Relevant randomized controlled trials (RCTs) were identified from PubMed, EMBASE, and Cochrane Central Register of Controlled Trials (Cochrane Library) databases. Ultimately, a total of seven RCTs with 8039 patients were included. Our meta-analysis demonstrated that dapoxetine (in the 30 mg and 60 mg subgroup) resulted in significantly higher IELT, PGIC, and AE incidence relative to the placebo, with higher proportions observed for 60 mg versus 30 mg of dapoxetine administration. The most common AEs were mild and tolerable. We conclude that dapoxetine (particularly the 60 mg dosage) may be considered a safe and effective drug for patients with PE.

 

Dapoxetine HCL Application:

 

Dapoxetine hydrochloride is a drug that is used to treat premature ejaculation in men. It is available by prescription and is taken orally, prior to sexual intercourse. The drug belongs to the class called serotonin reuptake inhibitors (SSRIs), which have mainly been used to treat depression.

 

Sexual dysfunction, including premature ejaculation, is an extremely common condition worldwide. The cause of premature ejaculation has not been fully elucidated, but may include both psychological and physiological factors. Premature ejaculation refers to a short ejaculation time, which can affect the satisfaction of both partners during sexual intercourse.

 

 

Peptides Carbetocin Acetate Contracting Uterus Control Bleeding 37025-55-1

 

Carbetocin Acetate Basic Info.:

 

Product Name: Carbetocin Acetate

Synonyms: (Butyryl1,Tyr(Me)2)-1-Carbaoxytocin Trifluoroacetate Salt;Carbetocin;Carbetocin Trifluoroacetate Salt;

CAS: 37025-55-1

MF: C45H69N11O12S

MW: 988.17

EINECS: 253-312-6

Storage temp.: -15°C

Product Categories: Peptide;Vasopressin and Oxytocin receptor;Intermediates & Fine Chemicals;Pharmaceuticals;Other APIs

Usage: An obstetric drug used to control postpartum hemorrhaging.

 

Carbetocin Acetate it is used to control bleeding after giving birth. Like oxytocin, it causes contraction of the uterus.

 

Ansion pharma is a factory providing pharmaceutical intermediate and custom synthesis service. 

 

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