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N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine 99%

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Pharmaceutical Raw Materials Desonide Used To Treat Atopic Dermatitis 638-94-8

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Pharmaceutical Raw Materials Desonide Used To Treat Atopic Dermatitis 638-94-8
 
Desonide Basic info:
 
Product Name: Desonide
Synonyms: Prednacinolone;Desonide;D-2083;Steroderm
CAS NO.: 638-94-8
Molecular Formula: C24H32O6
Molecular Weight: 416.51
EINECS: 211-351-6
Assay: 99.5%
Melting point: 272-274°C
Storage temp.: Refrigerator
Appearance: White powder
Product Categories: Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;Steroids;SPORANOX;Hormone Drugs.
Usage: 
(1)With acetal-based adrenal cortex hormones;
(2)Antifungal;
(3)Anti-inflammatory. Desonide has also been found as an impurity in budesonide (B689490).
How to use desonide topical: Use this medication only on the skin.
 
Desonide Description:
 
Desonide Ointment, 0.05% contains Desonide (Pregna - 1,4 - diene - 3,20 - dione,11,21 - dihydroxy - 16,17 - [(1 - methylethylidene)bis(oxy)] - ,(11β,16α)) a synthetic corticosteroid for topical dermatologic use. The corticosteroids constitute a class of primary synthetic steroids used topically as anti-inflammatory and antipruritic agents.
 
Chemically, Desonide, the active ingredient in Desonide Ointment, 0.05% is C24H32O6. It has the following structural formula:
 
The molecular weight of Desonide is 416.51. It is a white to off-white powder. The solubility of Desonide in distilled water saturated with ether is 184 mg/L.
Each gram of Desonide Ointment, 0.05% contains 0.5 milligram of Desonide microdispersed in a base of white petrolatum.
 
Desonide Application:
 
Desonide belongs to the group of medications known as topical corticosteroids. It is used to Treat various skin conditions, including rashes. It works by reducing inflammation and itching.
 
Endogenous eczema clinical cure rate, the overall curative effect is distinct, and the low Incidence of adverse reactions, is a safe and effective external cortex hormone.
 
Wash your hands. Before applying the medication, clean and dry the affected area. Apply a thin film of the medication to the affected area and gently rub in, usually 2-3 times daily, or as directed by your doctor. If using the gel, apply the gel usually only 2 times daily. Do not bandage, wrap, or cover the area unless you are instructed to do so by your doctor. If used in the diaper area on an infant, do not use tight-fitting diapers or plastic pants.
 
After applying the medication, wash and dry your hands, unless you are using this medication to treat the hands. When applying this medication near the eyes, avoid getting it in the eyes because this may worsen or cause glaucoma, or cause irritation. Also, avoid getting this medication in the nose or mouth. If you get this medication in your eyes, nose, or mouth, rinse immediately with plenty of water.
 

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(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol 99%

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6-Oxo Muscle Building Steroids 4-Androstene-3 to Increase Muscle Mass 2243-06-3

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6-Oxo Muscle Building Steroids 4-Androstene-3 to Increase Muscle Mass 2243-06-3
 
6-OXO Basic Info.
 
Product Name: 6-OXO
Alias: 4-androstene-3, 6, 17- trione; Androst-4-ene-3, 6, 17-trione; 4-Androstenetrione; 4-Androstenetriol
CAS: 2243-06-3
Molecular Weight: 300.39
Molecular Formula: C19H24O3
Melting Point: 223-224° C
Package: Foil bag or tin, or as you require
Properties: White powder
Usage: Steroid drug intermediates. Low Estrogen Levels. 
Payment: T/T, Western Union and Money Gram
Delivery: Within 12hours After Your Payment
Express: EMS, DHL, FedEx, etc(door-to-door) 
 
6-OXO Description:
 
6 OXO refer to the same chemical compound that is a steroidal testosterone booster/anti-aromatase agent. First identified in cow adrenal glands it was further found to be a natural metabolite of androstenedione metabolism in humans and most mammals. This makes 6 OXO a perfectly legal dietary supplement under the current DSHEA law and since it is not androgenic, not at all an anabolic steroid. What 6 OXO does is reduce an enzyme in the body that turns your testosterone into estrogen. By blocking this enzyme two major things happen, first it causes you to keep more of your testosterone and second, the body senses a lack of estrogen and causes the testes to release more testosterone.
 
6 OXO has been well studied in men and the original manufacturer of 6 OXO, Ergopharm Inc actually paid for quite a few studies in both men and rats. The most telling one was done by Incledon, which studied 6 OXO in doses of 300mg in healthy men, then measured the effects. The Incledon study found a boost of testosterone of about 200% with a slight reduction in estradiol, which means it was very effective at boosting testosterone while reducing estrogen. This was the first really well tested testosterone booster on the market.
 
Applications Of 6-OXO:
 
Study delivered a dose of 50 mg of 1-DHEA for 10 months with no serious adverse events reported.
1-DHEA was administered at a dose of 200 mg/day for 24 weeks with slight androgenic effects noted.
 

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High Quality Local Anesthetic Prilocaine Hydrochloride Prilocaine HCl 1786-81-8

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High Quality Local Anesthetic Prilocaine Hydrochloride Prilocaine HCl 1786-81-8
 
Prilocaine HCL Basic Info.:
 
Product Name: Prilocaine HCL
CAS: 1786-81-8
English name: Propitocaine hydrochloride
Other name: Prilocaine hydrochloride; 2 - propylamine base - o C amide toluene hydrochloride; Prilocaine hydrochloride; Prilocaine hydrochloride
Molecular formula: C13H21ClN2O
EINECS: 217-244-0
Molecular Weight: 256.7716
 
Prilocaine HCL Description:
 
Propitocaine hydrochloride is a local anesthetic of the amino amide type first prepared by Claes Tegner and Nils Lö Fgren. In its injectable form, it is often used in dentistry. It is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/prilocaine or EMLA), for treatment of conditions like paresthesia. As it has low cardiac toxicity, it is commonly used forintravenous regional anaesthesia.
 
In some patients, a metabolite of prilocaine may cause the unusual side effect of methemoglobinemia, which may be treated with methylene blue.
 
Local anesthetic is a substance that causes loss of sensation only to the area to which it is applied without affecting consciousness. Most local anesthetics structures have amino-ester or an amino-amide group which are linked to hydrophilic (secondary or tertiary amine) and to hydrophobic group (aromatics) on the other side.
 
Local anesthetics, long duration, lower toxicity, chemicals that are also small Suitable for epidural anesthesia, block anesthesia and infiltration anesthesia, etc.
 

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Methyl 4-{5-[bis(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazol-2 -yl}butanoate

Name:Methyl 4-{5-[bis(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazol-2 -yl}butanoate

CAS:109882-31-7

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Women Prohormones Steroids Progestone Progesterone Hormon Altrenogest 850-52-2

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Women Prohormones Steroids Progestone Progesterone Hormon Altrenogest 850-52-2 
 
Altrenogest Basic Info.
 
Product Name: Altrenogest 
CAS No.: 850-52-2  
Formula: C21H26O2  
Molecular Weight: 310.47  
EINECS: 212-703-1  
Density: 1.15 g/cm3  
Boiling Point: 495.6 °C at 760 mmHg  
Flash Point: 210.1 °C    
Storage: store in cool, dry, ventilated place.
PackAge: Foil Bag or According to Your Requirements.
 
Altrenogest Application:
 
Altrenogest is indicated (labeled) to suppress estrus in mares to allow a more predictable occurrence of estrus following withdrawal of the drug. It is used clinically to assist mares to establish normal cycles during the transitional period from anestrus to the normal breeding season often in conjunction with an artificial photoperiod. It is more effective in assisting in pregnancy attainment later in the transition period. One group of authors (Squires et al. 1983) suggest selecting mares with considerable follicular activity (mares with one or more follicles 20 mm or greater in size) for treatment during the transitional phase. Mares that have been in estrus for 10 days or more and have active ovaries are also considered to be excellent candidates for progestin treatment.
 
Altrenogest is effective in normally cycling mares for minimizing the necessity for estrus detection, for the synchronization of estrus and permitting scheduled breeding. Estrus will ensue 2-5 days after treatment is completed and most mares ovulate between 8-15 days after withdrawal. Altrenogest is also effective in suppressing estrus expression in show mares or mares to be raced. Although the drug is labeled as contraindicated during pregnancy, it has been demonstrated to maintain pregnancy in oophorectomized mares and may be of benefit in mares who abort due to sub-therapeutic progestin levels.
 
Altrenogest Adverse Effects/Warnings:
 
Adverse effects of altrenogest appear to be minimal when used at labeled dosages. One study (Shideler et al. 1983) found negligible changes in hematologic and most "standard" laboratory tests after administering altrenogest to 4 groups of horses (3 dosages, 1 control) over 86 days. Occasionally, slight changes in Ca++, K+, alkaline phosphatase and AST were noted in the treatment group, but values were only slightly elevated and only noted sporadically. No pattern or definite changes could be attributed to altrenogest. No outward adverse effects were noted in the treatment group during the trial.
 
The following people should not handle the product:
1).Women who are or suspect that they are pregnant
2).Anyone with thrombophlebitis or thromboembolic disorders or with a history of these events
3).Anyone having cerebrovascular or coronary artery disease
4).Women with known or suspected carcinoma of the breast
5).People with known or suspected estrogen-dependent neoplasia
6).Women with undiagnosed vaginal bleeding
7).People with benign or malignant tumor which developed during the use of oral contraceptives or other estrogen containing products.
 

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(2S,4S)-1-(tert-butoxycarbonyl)-4-(MethoxyMethyl)pyrrolidine-2-carboxylic acid 99%

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2-(2-(4-Fluorophenyl)-2-oxo-1-phenylethyl)-4-methyl-3-oxo-N-phenylpentanamide 99%

Ansion pharma is a factory providing pharmaceutical intermediate and custom synthesis service. 
 
More products infomation, pls contact us: ann.xu@ansionpharma.com; www.ansionpharma.com

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98% Injectable Polypeptide Hormones Eptifibatide Raw Steroid Powders 148031-34-9

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98% Injectable Polypeptide Hormones Eptifibatide Raw Steroid Powders 148031-34-9
 
Eptifibatide Basic Info.
 
Product Name: Eptifibatide
Synonyms: Human Eptifibatide; Eptifitide
Sequence: Mpr-Har-Gly-Asp-Trp-Pro-Cys-NH2
Cas No.: 148031-34-9
Molecular Formula: C35H49N11O9S2
Molecular Weight: 831.96
Appearance: White slightly yellwish powder.
Specific Rotation[20/D]: -75.0~-95.0°(C=1,1%HAc)
Amino Acids composition: ± 10%
Peptide Purity (By HPLC): >98% by area integration.
Related Substance (By HPLC): Total Impurities (%)<2.0%;Largest Single Impurity (%)< 1.0%
Water Content (Karl Fischer): <8.0%
Peptide Content(N determination): >80%
Acetate Content: <15%
IR spectrum: in accordance
Grade : Pharmaceutical Grade
Storage: Closed, below 2 ~ 8ºC preservation
Usage : Platelet glycoprotein receptor antagonist model, the third generation of antiplatelet drugs. For acute coronary syndrome (including unstable angina or non Q wave myocardial infarction) or percutaneous coronary interventional therapy (including angioplasty or atheromatous plaque excision).
 
Description Of Eptifibatide:
 
Eptifibatide (Integrilin, Millennium Pharmaceuticals, also co-promoted by Schering-Plough/Essex), is an antiplatelet drug of the glycoprotein IIb/IIIa inhibitor class.[1] Eptifibatide is a cyclic heptapeptide derived from a protein found in the venom of the southeastern pygmy rattlesnake (Sistrurus miliarius barbouri). It belongs to the class of the so-called arginin-glycin-aspartat-mimetics and reversibly binds to platelets. Eptifibatide has a short half-life. The drug is the third inhibitor of GPIIb/IIIa that has found broad acceptance after the specific antibody abciximab and the non-peptide tirofiban entered the global market.
Integrilin is sold in two strengths, globally: vials containing 2 mg/ml (20 mg totally) and 0.75 mg/ml (75 mg totally).
 
Application Of Eptifibatide:
 
Eptifibatide is used to reduce the risk of acute cardiac ischemic events (death and/or myocardial infarction) in patients with unstable angina or non-ST-segment-elevation (e.g., non-Q-wave) myocardial infarction (i.e., non-ST-segment elevation acute coronary syndromes) both in patients who are to receive non surgery (conservative) medical treatment and those undergoing percutaneous coronary intervention (PCI).
 
The drug is usually applied together with aspirin or clopidogrel and (low molecular weight or unfractionated) heparin. Additionally, the usual supportive treatment consisting of applications of nitrates, beta-blockers, opioid analgesics and/or benzodiazepines should be employed as indicated. Angiographic evaluation and other intensive diagnostic procedures may be considered a first line task before initiating therapy with eptifibatide.
 

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