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99.5% Purity USP Female Steroidal Progestin Hormone Megestrol Acetate CAS 595-33-5

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99.5% Purity USP Female Steroidal Progestin Hormone Megestrol Acetate CAS 595-33-5
 
Megestrol Acetate Basic Info.:
 
Product Name: Megestrol acetate
CAS: 595-33-5
MF: C24H32O4
MW: 384.51
EINECS: 209-864-5
mp: 214°C
refractive index: 11°(C=2, CHCl3)
Chemical Properties: Crystalline Solid
Usage:Progestogen;Progesterone receptor agonist,Orally active progestogen; formerly used in combinations as oral contraceptive,treatment of endometrial hyperplasia.
 
Megestrol Acetate Description:
 
Megestrol acetate is used mainly as an appetite stimulant in a variety of conditions and as an antineoplastic agent in the treatment of breast, endometrial, and prostate cancers.
 
When given in relatively high doses, it can substantially increase appetite in most individuals, even those with advanced cancer, and is often used to boost appetite and induce weight gain in patients with cancer or HIV/AIDS-associated cachexia. It is also used as a contraceptive in combination with an estrogen at relatively low doses.
 
Megestrol Acetate Application:
 
Megestrol acetate is used mainly as an appetite stimulant in a variety of conditions and as an antineoplastic agent in the treatment of breast, endometrial, and prostate cancers. When given in relatively high doses, it can substantially increase appetite in most individuals, even those with advanced cancer, and is often used to boost appetite and induce weight gain in patients with cancer or HIV/AIDS-associated cachexia. It is also used as a contraceptive in combination with an estrogen at relatively low doses.
In addition to its use in humans, megestrol acetate has been used extensively in veterinary medicine in the treatment of medical conditions in cats and dogs.
 
Megestrol Acetate Usage:
 
Megestrol acetate is available as 5 mg, 20 mg and 40 mg tablets and in oral suspensions of 125 mg/ml and 40 mg/ml. It is used at a dose of 5 mg in combination with an estrogen for contraception. Appetite stimulation is achieved with doses ranging from 400 mg to 800 mg a day. Doses used to treat cancer usually range from 40 mg to 320 mg.
 

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Muscle Growth Steriods Polypeptide Hormone Oxytocin 50-56-6 For Hasten Parturition

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Muscle Growth Steriods Polypeptide Hormone Oxytocin 50-56-6 For Hasten Parturition
 
Oxytocin Basic Info.:
 
Product Name: Oxytocin
Synonyms: Oxytocin Acetate Salt Hydrate;Ocytocinum;Alpha-Hypophamine 
Unit Size: 2 mg/vial 
Unit Quantity: 1 Vial 
CAS NO.: 50-56-6 
Molecular Formula: C43H66N12O12S2 
Molecular Mass: 1,007.19    
Appearance: White Powder 
Purity: 98.2%  
Source: Chemical Synthesis 
Storage: Lyophilized Oxytocin is stable at room temperature for 90 days,however it should be stored in a freezer below -8C for any extended period of time. After reconstituting Oxytocin should be refrigerated at temperatures not to exceed 36 F.
 
Oxytocin Description:
 
Oxytocin is a hormone that is made in the brain, in the hypothalamus, and it is transported to, and secreted by, the pituitary gland, which is located at the base of the brain.
 
Chemically it is known as a nonapeptide (a peptide containing nine amino acids), and biologically, as a neuropeptide. It acts both as a hormone and as a brain neurotransmitter.
In both men and women, sexual intercourse stimulates the release of oxytocin, which has a role in erection and orgasm. The reason for this is not fully understood, although in women, it has been proposed that the increased uterine motility may help sperm to reach their destination.
 
The research to uncover oxytocin's "anxiolytic and pro-social influences, beneficial to relief, reproduction, and love" is what has led scientists to describe it as a one of the "most promising neuromodulator/neurotransmitter systems of the brain for psychotherapeutic intervention and treatment of numerous psychiatric illnesses, for example social phobia, autism, and postpartum depression.
 
Oxytocin (Oxt) is a mammalian neurohypophysial hormone. Produced by the hypothalamus and stored and secreted by the posterior pituitary gland, oxytocin acts primarily as a neuromodulator in the brain.
Oxytocin plays an important role in the neuroanatomy of intimacy, specifically in sexual reproduction of both sexes, in particular during and after childbirth; its name, meaning "swift childbirth", comes from Greek, oksys "swift" and , tokos "birth." It is released in large amounts after distension of the cervix and uterus during labor, facilitating birth, maternal bonding, and, after stimulation of the nipples, lactation. Both childbirth and milk ejection result from positive feedback mechanisms.
 
Oxytocin Application:
 
Injected oxytocin analogues are used for labor induction and to support labor in case of difficult parturition. It has largely replaced ergometrine as the principal agent to increase uterine tone in acute postpartum hemorrhage. Oxytocin is also used in veterinary medicine to facilitate birth and to stimulate milk release. The tocolyticagent atosiban (Tractocile) acts as an antagonist of oxytocin receptors; this drug is registered in many countries to suppress premature labor between 24 and 33 weeks of gestation. It has fewer side effects than drugs previously used for this purpose (ritodrine).
 

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Sex Enhancement Medicine Avanafil For Treating Male Sexual Dysfunction 330784-47-9

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Sex Enhancement Medicine Avanafil For Treating Male Sexual Dysfunction 330784-47-9
 
Avanafil Basic Info:
 
Product Name: Avanafil
CAS: 330784-47-9
Molecular Formula: C23H26ClN7O3
Molecular Weight: 483.9506
Character: White to Off-White Cyrstalline Solid.
Assay: 99% min.
Store: Store at room temperature away from moisture, heat, and light.
Product Categories: Aromatics;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Inhibitor;Avanafil;Inhibitors
Usage: Used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor.
 
Avanafil Description:
 
Avanafil is a PDE5 inhibitor approved for erectile dysfunction by the FDA and EMA,it acts by inhibiting a specific phosphodiesterase type 5 enzyme which is found in various body tissues, but primarily in the corpus cavernosum penis and retina.Avanafil works the same way as the three other ED drugs currently on the market: Viagra, Cialis, and Levitra. All these drugs target an enzyme called PDE5,and avanafil appears to inhibit this enzyme more selectively than the other. It is absorbed quickly, reaching a maximum concentration in about 30-45 minutes. About two-thirds of the participants were able to engage in sexual activity within 15 minutes.Avanafil's most frequent side effect was headache, and the other common side effects included flushing and nasal congestion,this new drug may have fewer side effects.
 
Avanafil Application:
 
Avanafil is used to treat male sexual function problems such as impotence or erectile dysfunction,it is in a class of medications called phosphodiesterase inhibitors.Avanafil works by increasing blood flow to the penis to help a man get and keep an erection.This drug does not protect against sexually transmitted diseases such as HIV, gonorrhea and syphilis.To decrease your risk of infection, always use an effective barrier method during all sexual activity.
 

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1-(4-fluorophenyl)-5-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]pentane-1,5-dione 99%

Ansion pharma is a factory providing pharmaceutical intermediate and custom synthesis service. 
 
More products infomation, pls contact us: ann.xu@ansionpharma.com; www.ansionpharma.com

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2-Aminomethyl-7-Chloro-2,3-Dihydro-5-(2-Fluorophenyl)-1h-1,4-Benzodiazepine Dimaleate

2-Aminomethyl-7-Chloro-2,3-Dihydro-5-(2-Fluorophenyl)-1h-1,4-Benzodiazepine Dimaleate is a Midazolam intermediate

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3-[(3-amino-4-methylamino-benzoyl)pyridine-2-yl-amino]propionic acid ethyl ester 99%

Ansion pharma is a factory providing pharmaceutical intermediate and custom synthesis service. 
 
More products infomation, pls contact us: ann.xu@ansionpharma.com; www.ansionpharma.com

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99% Antiestrogen Steroid Hormones Toremifene Citrate For Cancer Patients 89778-27-8

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99% Antiestrogen Steroid Hormones Toremifene Citrate For Cancer Patients 89778-27-8

Toremifene Citrate Basic Info.

Product Name: Toremifene Citrate

Synonyms: FC 1157a; Fareston; NK 622; NSC 613680

CAS: 89778-27-8

Molecular Formula: C32H36ClNO8

Molecular Weight: 598.08

Melting point: 160-162°C

Boiling point: 146-148C

Density: 1,045g/cm

Refractive index: 1,416-1,418

Storage temp.: -20°C Freezer

Appearance: White or almost white powder

Toremifene Citrate Descriptions:

Fareston will display both estrogen antagonist / agonist properties in the body. This puts Fareston in the same category as Nolvadex and Clomid, the two most popular drugs in Farestons category. FARESTON is an estrogen agonist/antagonist indicated for the treatment of metastatic breast cancer in postmenopausal women with estrogen-receptor positive or unknown tumors.

Toremifene administration for a period of 3 months in men with idiopathic oligozoospermia is associated with significant improvements of sperm count, motility, and morphology, mediated by increased gonadotropin secretion and possibly a direct beneficial effect of toremifene on the testes. The above findings are also indicative of a better testicular exocrine (improved sperm parameters) response to treatment in men whose partners achieved pregnancy compared with those who did not. Further randomized, placebo-controlled trials should be conducted to determine whether this particular selective estrogen receptor modulator can be useful as an initial approach in men with oligozoospermia.

Toremifene Citrate Applications:

Toremifene Citrate improved lipid profiles, particularly as an enhancer of high density lipoprotein cholesterol. it improved low density lipoprotein cholesterol levels.Both fareston and tamoxifen selective estrogen receptor modulators and equivalent treatments for metastatic breast cancer.No significant differences were found between treatment with either tamoxifen or fareston Treatment of HR-positive patients with either tamoxifen or toremifene is appropriate.In treating idiopathic oligozoospermia, tamoxifen and fareston are roughly equally effective but raloxifene is not.The antiestrogenic effects of SERMs at the hypothalamic level result in a statistically significant increase of gonadotropin levels, which is more marked for tamoxifen and fareston compared with raloxifene.

 

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99% Purity Muscle Building Steroids Peptide Powder Sermorelin For Alduts 86168-78-7

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99% Purity Muscle Building Steroids Peptide Powder Sermorelin For Alduts 86168-78-7
 
Sermorelin Description:
 
Product Name: Sermorelin
Alias: GRF 1-29 NH2, Sermorelin Acetate Hydrate
Sequence: H-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH2
CAS: 86168-78-7
MF: C149H246N44O42S
MW: 3357.96
Purity: 99%
Specification: 2mg/vial
Appearance: White Lyophilized Powder
Place of Origin: China
Standard: USP
Certification: SGS
Method of Analysis: HPLC
Storage: Lyophilized peptides although stable at room temperature for 3 months, should be stored desiccated below -18°C. Upon reconstitution of the peptide it should be stored at 4°C between 2-21 days and for future use below -18°C.
 
Sermorelin Details:
 
Sermorelin acetate is a recently synthesized (man-made) peptide analogue of growth hormone releasing hormone (GHRH) a naturally occurring hormone that is produced in the hypothalamus and stimulates and controls the production of growth hormone (GH) within the pituitary gland. GHRH, which is necessary for growth and development, was first described by Nobel Laureates R. Guilleman and A Shalley. In the 1970s one of their students, William Wehrenberg, began studying which part of the GHRH molecule was essential in stimulating the pituitary gland.
 
By removing individual amino acids from the GHRH molecule, Wehrenberg found that only the first 29 amino acids were essential for the stimulation of GH production in the pituitary gland. Semorelin is therefore only comprised of these 29 essential amino acids, forming a short polypeptide chain that is considered one of the shortest functional fragments of the GHRH molecule. It was first developed with a one-step chromatographic method capable of separating all isomers of polyethylene glycol (PEG) from naturally occurring GHRH.
 
Sermorelin Effect:
 
Sermorelin has a wide range of positive effects. Due to its nature as a GHRH, sermorelin only increases the body's ability to produce more growth hormone; it is not an injection of growth hormone itself. In both a performance enhancing and general well-being sense, sermorelin has a wide array of benefits that make it a powerful and valuable substance.
 

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Anabolic Androgenic Steroids Estradiol Benzoate For Female Sex Enhancement 50-50-0

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Anabolic Androgenic Steroids Estradiol Benzoate For Female Sex Enhancement 50-50-0 
 
Estradiol Benzoate Basic Info.:
 
Product Name: Estradiol Benzoate
Synonyms: (17beta)-Estra-1,3,5(10)-triene-3,17-diol 3-benzoate;1,3,5(10)-Estratriene-3,17-diol-3-benzoate;1,3,5(10)-Oestratriene-3,17-beta-diol 3-benzoate;1,3,5(10)-oestratriene-3,17-beta-diol3-benzoate;17beta-Estradiol monobenzoate;17-beta-estradiolmonobenzoate;17-beta-Oestradiol 3-benzoate;17-beta-oestradiol3-benzoate 
CAS: 50-50-0 
MF: C25H28O3 
MW: 376.49 
EINECS: 200-043-7 
Chemical Properties White solid 
Usage antiacne, antineoplastic 
Usage Estradiol is the major estrogen secreted by the premenopausal ovary. Estradiol benzoate is an estradiol analog which contains a benzyl ester at the C-3 position. Estradiol benzoate is useful in the tr eatment of lesions produced by diminution of bodily production of estrogens.
 
Estradiol Benzoate Description:
 
Estrogens direct the development of the female genotype in embryogenesis and at puberty. Estradiol is the major estrogen secreted by the premenopausal ovary. Estradiol benzoate is an estradiol analog which contains a benzyl ester at the C-3 position and is often used in combination with a progestin to induce estrus in domestic livestock. This compound binds to the human and murine estrogen receptor α (ERα), and chicken ER with IC50 values in the range of 22-28 nM. This reflects a 6-10 fold reduction in binding affinity compared to estradiol.
 
Estradiol Benzoate Applications:
  
The effects of daily injections of 5 microgram estradiol benzoate (EB) on the patterns of food and ethanol consumption were studied in ovarectomized rats given free access to food, a 10% ethanol solution, and water. EB led to an immediate, but transient, suppression of both food and ethanol intake. The time course and magnitude of these effects were virtually identical. While the decrease in total food intake was achieved by a permanent decrease in the duration of eating bouts, the decline in total ethanol consumption apparently resulted from decreased rates of licking within bouts. Gradual increases in the frequency of eating and ethanol-drinking bouts allowed total food and ethanol intake to return to baseline within three weeks of the first injection. Total water intake rose three-fold during EB administration and this was due to increases in both the duration and frequency of drinking bouts. The similarity in effects induced by EB on the patterns of food and ethanol intake were discussed in terms of ethanol's caloric property.
 

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Anabolic Trenbolone Steroids Powder Trenbolone Hexahydrobenzyl Carbonate 23454-33-3

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Anabolic Trenbolone Steroids Powder Trenbolone Hexahydrobenzyl Carbonate 23454-33-3
 
Trenbolone Hexahydrobenzyl Carbonate Basic Info.
 
Product Name: Trenbolone Cyclohexylmethylcarbonate
Alias: Parabolan; Trenbolone Hexahydrobenzyl Carbonate
CAS No: 23454-33-3
MF: C26H34O4
MW: 410.55
Einecs No: 245-669-1
Purity: 98%
Appearance: Yellow powder.
 
Trenbolone Hexahydrobenzyl Carbonate Description:
 
Parabolan is trenbolone cyclohexylmethylcarbonate. The half-life of a steroid ester is mostly dependent on its ratio of fat solubility to water solubility: the longer chain the ester, the higher this ratio, and the longer the half-life. This particular carbonate could be most closely compared with an enanthate ester; the half-life is probably a little less than week. 
 
Trenbolone Hexahydrobenzyl Carbonate Applications:
 
High Purity Parabolan/Trenbolone cyclohexylmethylcarbonate/Trenbolone Hexahydrobenzyl carbonate/CAS No: 23454-33-3 Protein assimilation hormonal.Trenbolone is a steroid used by veterinarians on livestock to increase muscle growth and appetite, to increase the half-time, trenbolone is not used in an unrefined form, but is rather administered as ester derivatives such as trenbolone acetate,trenbolone enanthate ortrenbolone cyclohexylmethylcarbonate, a normal bodybuilding dosage can range from 200mg/week to 1400mg/ week. Trenbolone acetate can be injected once a week, also trenbolone acetate is often refined to as "Fina" by user, trenbolone compounds have a binding affinity for the androgen receptor five times as high as that of testosterone.
 

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