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Pharmaceutical Grade Raw Material Chitosan CAS 9012-76-4 For Food

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Pharmaceutical Grade Raw Material Chitosan CAS 9012-76-4 For Food
 
Chitosan Basic information
 
Product Name: Chitosan
Synonyms: POLY(BETA-(1,4)-2-AMINO-2-DEOXY-D-GLUCOSE);POLY(BETA-(1,4)-D-GLUCOSAMINE);POLY(D-GLUCOSAMINE);POLY-(1,4-BETA-D-GLUCOPYRANOSAMINE);POLY-[1->4]-BETA-D-GLUCOSAMINE;BETA-(1,4)-2-AMINO-2-DEOXY-D-GLUCOSE;DEACETYLATED CHITIN;CHITOSAN
CAS: 9012-76-4
MF: C6H11NO4X2
MW: 161.16
EINECS: 222-311-2
Storage temp.: room temp
Solubility: dilute aqueous acid (pH <6.5).: soluble
Stability: Stable. Incompatible with strong oxidizing agents.
Chemical Properties: faintly beige solid  (Coarse ground flakes and powder)
Product Categories: Miscellaneous Natural Products;Biochemistry;Polysaccharides;Sugars;Nutritional Supplements;Dextrins、Sugar & Carbohydrates;Activity Other;Carbohydrate adjuvants;Carbohydrates A-C;Chitosan and Chitin;Activity;and Substrates;Biochemicals and Reagents;Carbohydrates;Carbohydrates A to Z;Cell Culture;Chitosan;Enzyme Substrates;Enzymes;Inhibitors;Materials Science;Natural Polymers;Polymer Science;Polymers;Polysaccharide;Vaccine Adjuvants;Vaccine Production;Oligosaccharide,Biostimulate
Usage: Claimed to have the ability to retain fats and cholesterol in the stomach.
Properties: This product is non-toxic, odorless, off-white or slight yellow powder, and soluble in acid, insoluble in water and base or normal organic solutions.
 
Chitosan Description:
 
Chitosan is a linear polysaccharide composed of randomly distributed β-(1-4)-linked D-glucosamine (deacetylated unit) and N-acetyl-D-glucosamine (acetylated unit). It is made by treating shrimp and other crustacean shells with the alkali sodium hydroxide.
 
Chitosan has a number of commercial and possible biomedical uses. It can be used in agriculture as a seed treatment and biopesticide, helping plants to fight off fungal infections. In winemaking it can be used as a fining agent, also helping to prevent spoilage. In industry, it can be used in a self-healing polyurethane paint coating. In medicine, it may be useful in bandages to reduce bleeding and as an antibacterial agent; it can also be used to help deliver drugs through the skin.
 
More controversially, chitosan has been asserted to have use in limiting fat absorption, which would make it useful for dieting, but there is evidence against this.
 
Other uses of chitosan that have been researched include use as a soluble dietary fiber.
 
Chitosan is extracted from chitin, insoluble in water but soluble in dilute acid and absorbed by human body. As the firdt derivate, it's chemical constitution is macromolecule alkalescent polysaccharide polymer with cation. It has peculiar physical, chemical properties and bioactive function.
 
Chitosan is listed as follows:
A. High Density Chitosan
B. High Viscosity Chitosan
C. Industrial Grade Chitosan
D. Food Grade Chitosan
E. Medical Grade Chitosan
F. Low Molecular Weight Chitosan
G. Aroxymethyl Chitosan
H. Chitosan Oligosaccharide
 
Chitosan Applications:
 
1)Food Field:
Used as food additives, thickeners, preservatives fruits and vegetables, fruit juice clarifying agent, forming agent, adsorbent, and health food.
2)Medicine, health care products field:
As the chitosan non-toxic,has anti-bacterial, anti-inflammatory, hemostatic, and immune function, can be used as artificial skin, self-absorption of surgical sutures, medical dressing Branch, bone, tissue engineering scaffolds, enhance liver function, improve digestive function, blood fat, lowering blood sugar, inhibiting tumor metastasis, and adsorption and complexation of heavy metals and can be excreted, and so on, was vigorously applied to health food and drug additives.
3)Environmental protection field:
Chitosan and its derivatives is a good flocculant for wastewater treatment and metal recovery from metal-containing waste water; in textile field: as a mordant, health care fabric, sizing agents, printing and dyeing
4).Agricultural field:
As growth promoters, bio-pesticides, feed additives, seeds, etc.
5)Field of tobacco
Tobacco sheet used as adhesives, low-tar filter and so on.
 
Chitosan is refined from deacetylation of chitin which is extracted from deep-sea Alaska crab cods. As the only basic polysaccharide among natural polysaccharides, this product has many physical and chemical characteristics and physiological activities. Precisely, this product can control cholesterol, inhibit bacterial activity, prevent and control high blood pressure, absorb and excrete heavy metals, maintain humidity and strengthen immunity. In food industry, this product can be used as antibacterial agent, fruit and vegetable preservative and antioxidant. There are many special functional groups in molecular chain, so the chitosan can be manufactured into many products according to different reactions on functional groups, such as acylation, sulfation and oxidation, grafting and crosslinking, hydroxyethylation and hydroxymethylation. These products can be used in many fields, including medicine, food, chemical, cosmetic, water treatment, metal extraction and recovery, biochemical and biomedical engineering. There are many types of chitosan, including GS-chitosan oligosaccharide, high density type, special molecular weight type, medical/food / industrial grade type, water soluble type and specialized type.
Chitosan can inhibit growth and reproduction of fungi, bacteria, and virus. When this product is used as coating preservation, it can inhibit respiratory metabolism and water loss of fruits and vegetables, thus slowing their aging process of organization and structure and effectively extending their postharvest life. This product can also be used as antioxidant. In heating process, free iron ions are released from meat hemoglobin and they form chelates with chitosan, thus their catalytic activity is inhibited.
 
Chitosan Usage:
 
Agricultural and horticultural use
The agricultural and horticultural uses for chitosan, primarily for plant defense and yield increase, are based on how this glucosamine polymer influences the biochemistry and molecular biology of the plant cell. The cellular targets are the plasma membrane and nuclear chromatin. Subsequent changes occur in cell membranes, chromatin, DNA, calcium, MAP Kinase, oxidative burst, reactive oxygen species, callose pathogenesis-related (PR) genes and phytoalexins.
 
Natural biocontrol and elicitor
In agriculture, chitosan is used primarily as a natural seed treatment and plant growth enhancer, and as an ecologically friendly biopesticide substance that boosts the innate ability of plants to defend themselves against fungal infections. The natural biocontrol active ingredients, chitin/chitosan, are found in the shells of crustaceans, such as lobsters, crabs, and shrimp, and many other organisms, including insects and fungi. It is one of the most abundant biodegradable materials in the world.
 

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Pharmaceutical Grade Reducing Fat Mass Chemicals Sr9011 SR-9011 1379686-29-9

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Pharmaceutical Grade Reducing Fat Mass Chemicals Sr9011 SR-9011 1379686-29-9
 
SR9011 Basic Info:
 
Product Name: SR9011
Synonyms: 3-(((4-chlorobenzyl)((5-nitrothiophen-2-yl)methyl)amino)methyl)-N-pentylpyrrolidine-1-carboxamide
CAS No: 1379686-29-9
Molucelar Formula: C23H31ClN4O3S
Molucelar Weight: 479.03524
Solubility: DMSO up to 100 mM
 
Sr9011 Description:
 
SR9011 is a trifunctional methacrylate monomer that provides exceptional adhesion to metal substrates.
SR9011 is recommended for use in peroxide cured coatings, sealants, and PVC-based plastisols. Usage levels of 5% to 10% by weight are recommended.
 
SR9011 is a potent and specific synthetic REV-ERB agonist that binds to REV ERB α with an EC50 ~790 nM and REV-ERB-β with EC50 ~560 nM. It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB-α and REV-ERB-β play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism. Administration of SR9011 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice. The circadian expression pattern of an array of metabolic genes in the liver, skeletal muscle and adipose tissue was also altered, resulting in increased energy expenditure. Treatment of diet induced obese mice with SR9011 decreased obesity by reducing fat mass and markedly improved dyslipidaemia and hyperglycaemia. These results indicate that synthetic REV-ERB ligands that pharmacologically target the circadian rhythm may be beneficial in the treatment of sleep disorders as well as metabolic diseases.
 
Sr9011 Application:
 
In vitro: SR9011 was used at 5-10 μM concentration in vitro and in cellular assays.
In vivo: IP administration of SR9011 was used at 100 mg/kg once or twice per day for 12-30 days in different mouse models.
 

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Pharmaceutical Grade Treatment Of Prostate Cancer Peptide Deslorelin Acetate 57773-65-6

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Pharmaceutical Grade Treatment Of Prostate Cancer Peptide Deslorelin Acetate 57773-65-6
 
Deslorelin Basic Info.:
 
Product Name: Deslorelin
Specification: 50mg*50vials/kit
Synonyms: GLP-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-NHET;Desorelin;Deslorelin; Deslorelin Acetate; Deslorelin (Human);
CAS: 57773-65-6
MF: C64H83N17O12
MW: 1282.45
Purity: 98%
Storage temp.: −20°C
Product Categories: Peptide;Hormones
Usage: Biochemical research;Clinical used in the treatment of prostate cancer.
 
Deslorelin Description:
 
Deslorelin acetate is an injectable gonadotropin releasing hormone super-agonist (GnRH agonist) also known as an LHRH agonist. It stops the production of sex hormones (and oestrogen). Deslorelin Acetate is marketed by Peptech with the brand name Ovuplant. It is currently approved for use in veterinary medicine and is used to induce ovulation in mares as part of the artificial insemination process. It is also used to stabilize high-risk pregnancies, mainly of livestock. Unlike other GnRH agonists, which are mainly used to inhibit uteinizing hormone and follicle-stimulating hormone by their ultimate downregulation of the pituitary gland, Deslorelin is primarily used for the initial flare effect upon the pituitary, and its associated surge of LH secretion.
 
Deslorelin Application:
 
Deslorelin was successfully trialed in the US and was approved for veterinary use under certain  circumstances. In Europe, it was approved for use in equine assisted reproduction. It is also being trialed in humans to study its efficacy in treatment of breast cancer in women,and in treating  precocious puberty and congenital adrenal hyperplasia in male and female children.
 

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Pharmaceutical Human Growth Hormone Peptide TB-500 Anti Inflammatory

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Pharmaceutical Human Growth Hormone Peptide TB-500 Anti Inflammatory
 
TB 500 Basic Info.:
 
Product Name: TB 500 
Synonyms:TB 500;TB500;Thymosin Beta 500
TB500 Appearance: White powder
TB500 CAS No.: 77591-33-4
TB500 MF: C212H350N56O78S
TB500 MW: 4963.49
TB500 Specification: 2mg/vial,10vials/kit
TB500 Purity (HPLC): 95%min
TB500 Amino Acid Composition: ± 10% of theoretical
TB500 Peptide Content (N%): ≥ 80.0%
TB500 Water Content(Karl Fischer): ≤ 5.0%
TB500 Acetate Content (HPIC): ≤ 15.0%
TB500 Single Impurity (HPLC): 2.0%max
TB500 MS(ESI): Consistent
 
TB 500 Description:
 
TB-500 is a synthetic fraction of the protein thymosin beta-4, which is present in virtually all human 
and animal cells. The main purpose of this peptide is to promote healing. It also promotes creation 
of new blood and muscle cells. The healing effects of TB-500 have been observed in tendons,
ligaments, muscle, skin, heart, and the eyes. Thymosin beta-4 is naturally produced in higher 
concentration where tissue has been damaged. This peptide is also a very potent anti-inflamatory 
agent. 
 
TB-500 is different from other repair factors (growth hormone, IGF-1), because it promotes 
endothelial and keratinocyte migration. It also does not bind to the extracellular matrix and has 
a very low molecular weight. Because of this it can travel long distances through the tissues in the 
human body. 
 
One of TB-500 key mechanisms of action is its ability to regulate the cell-building protein - Actin. 
Of the thousands of proteins present within human cells, actin represents roughly 10% of the total.
It is thus a vital component of cell structure and movement.
 
TB-500 was identified as a gene that was up-regulated four-to-six fold during early blood vessel
formation and found to promote the growth of new blood cells from the existing vessels. This peptide is present in wound fluid and when administered subcutaneously, it promotes wound healing, muscle building and speeds up recovery time of muscles fibres and their cells. An additional key factor of
TB-500 is that it promotes cell migration through a specific interaction with actin in the cell cytoskeleton.
It has been demonstrated that a central small amino acid long-actin binding domain has both blood cell reproduction and wound healing characteristics. These characteristics are uncovered by accelerating
the migration of endothelial cells and keratinocytes. It also increases the production of extracellular matrix-degrading enzymes.
 
TB 500 Application:
 
TB-500 is different from other repair factors because it promotes endothelial and keratinocyte migration. It also does not bind to the extracellular matrix and has a very low molecular weight.Because of this it can travel long distances through the tissues in the human body. 
 
TB-500 is a synthetic fraction of the protein thymosin beta-4, which is present in virtually all human and animal cells. The main purpose of this peptide is to promote healing. It also promotes creation of new blood and muscle cells. The healing effects of TB-500 have been observed in tendons, ligaments, muscle, skin, heart, and the eyes. Thymosin beta-4 is naturally produced in higher concentration where tissue has been damaged. This peptide is also a very potent anti-inflamatory agent.
 

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Pharmaceutical Intermediate Anti-Estrogen Clomiphene Citrate Steroid Hormone Powder Clomid 50-41-9

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Pharmaceutical Intermediate Anti-Estrogen Clomiphene Citrate Steroid Hormone Powder Clomid 50-41-9
Male Anti Estrogenic Clomid for Steroid Cycle Clomiphene
 
Clomid Basic Info.:
 
Product Name: Clomid (Clomiphene Citrate)
Alias: Clomid;Clomifen;Clomiphene;Clomiphene Citrate;Serophene;Pergotime;Clomphid;Clomiphene Citrate Salt.
CAS No: 50-41-9
MF: C32H36ClNO8
MW: 598.09
Einecs No: 200-035-3
Purity: 99%
Melting point: 116.5-118°C
Storage temp.: 2-8°C
Appearance: Crystalline Solid; Odourless.
Product Categories: API;Intermediates & Fine Chemicals;Pharmaceuticals;Amines;Aromatics;Peptides;CLOMID
Usage:
(1)An unducer of ovulation. A gonad-stimulating principle
(2)Synthetic estrogen agonist-antagonist. Gonad-stimulating principle.
(3)A selective estrogen receptor modulator
 
Clomid Description:
 
Clomid is a mixed estrogen agonist/antagonist (activator/blocker) which, when bound to the estrogen receptor, puts it in a somewhat different conformation (shape) than does estradiol. The estrogen receptor requires binding of an estrogen or drug at its binding site and also the binding of any of several cofactors at different sites. Without the binding of the cofactor, the estrogen receptor is inactive. Different tissues use different cofactors. Some of these cofactors are able to bind to the estrogen receptor/Clomid complex, but others are blocked due to the change in shape. The result is that in some tissues Clomid acts as an antagonist - the cofactor used in that tissue cannot bind and so the receptor remains inactive - and in others Clomid acts as an agonist (activator), because the cofactors used in that tissue are able to bind. 
 
Clomid Applications:
 
Steroids Hormone Clomiphene Citrate/Clomid powders/CAS No: 50-41-9
Clomid is the anti-estrogen of choice for improving recovery of natural testosterone production after a cycle, improving testosterone production of endurance athletes, and is also effective in reducing risk of gynecomastia during a cycle employing aromatizable steroids. 
 

 

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Pharmaceutical Intermediate Powder Peptide Lanreotide For Acromegaly 108736-35-2

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Pharmaceutical Intermediate Powder Peptide Lanreotide For Acromegaly 108736-35-2 
 
Lanreotide Basic Info.:
 
Product Name: Lanreotide
Synonyms: Lanreotide;Autogel;Bim-23014;Angiopeptin;Ipstyl 
CAS: 108736-35-2
MF: C54H69N11O10S2
MW: 1096.32
Storage temp.: −20°C
Chemical Properties: White to off-white lyophilised powder
Product Categories: hormones
 
Lanreotide Description:
 
Lanreotide (INN) is a medication used in the management of acromegaly and symptoms caused by neuroendocrine tumors, most notably carcinoid syndrome. It is a long-acting analogue of somatostatin, like octreotide. Its sequence is H-D-2Nal-Cys(1)-Tyr-D-Trp-Lys-Val-Cys(1)-Thr-NH2.
 
Lanreotide is used in the treatment of acromegaly, due to both pituitary and non-pituitary growth hormone-secreting tumors, and the management of symptoms caused by neuroendocrine tumors, particularly carcinoid tumors and VIPomas. In the United States and Canada, lanreotide is only indicated for the treatment of acromegaly. In the United Kingdom, it is also indicated in the treatment of thyrotrophic adenoma,a rare tumor of the pituitary gland which secretes TSH.
 
Lanreotide also shows activity against non-endocrine tumors, and, along with other somatostatin analogues, is being studied as a possible general antitumor agent.
 
Lanreotide Indications:
 
Lanreotide is used in the treatment of acromegaly, due to both pituitary and non-pituitary growth hormone-secreting tumors, and the management of symptoms caused by neuroendocrine tumors, particularly carcinoid tumors and VIPomas.  In the United States and Canada, lanreotide is only indicated for the treatment of acromegaly. In the United Kingdom, it is also indicated in the treatment of thyrotrophic adenoma, a rare tumor of the pituitary gland which secretes.
 
Lanreotide also shows activity against non-endocrine tumors, and, along with other somatostatin analogues, is being studied as a possible general antitumor agent.
 
Lanreotide ,In Dec 2014 the US FDA approved lanreotide for the treatment of patients with unresectable, well or moderately differentiated, locally advanced or metastatic gastroenteropancreatic neuroendocrine tumors (GEP-NETs).
 
Lanreotide Side Effects:
 
Lanreotide ,The main side effects of lanreotide treatment are mild to moderate pain at the injection site and gastrointestinal disturbances, such as diarrhea, nausea and vomiting. Isolated cases of gallstone formation have been associated with use of lanreotide, particularly over long periods of time.
 

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Pharmaceutical Raw Material Flutamide For Cancer Treament 13311-84-7

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Pharmaceutical Raw Material Flutamide For Cancer Treament 13311-84-7
 
Flutamide Basic Info.:
 
Product Name: Flutamide 
Synonyms: Timtec-bb sbb006930;Flutamide;Aurora ka-860
CAS: 13311-84-7 
MF: C11H11F3N2O3 
MW: 276.21 
EINECS: 236-341-9 
Chemical Properties: Light Yellow Solid 
Standard: Enterprise Standard 
Packing: foil bag or as required
Product Categories: Antitumors for Research and Experimental Use;Biochemistry;Amines;Aromatics;Pharmaceutical raw material 
 
Flutamide Usage:
 
Neuroleptic, Flutamide is a nonsteroidal antiandrogen drug, antineoplastic (hormonal). 
 
Flutamide Features:
 
For prostate cancer or benign prostatic hypertrophy. This product with bright prolyl Lee Teuk combination (should also start and at the same time, the continued use of) for the treatment of metastatic prostate
cancer, can significantly increase the efficacy.
 

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Pharmaceutical Raw Materials Desonide Used To Treat Atopic Dermatitis 638-94-8

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Pharmaceutical Raw Materials Desonide Used To Treat Atopic Dermatitis 638-94-8
 
Desonide Basic info:
 
Product Name: Desonide
Synonyms: Prednacinolone;Desonide;D-2083;Steroderm
CAS NO.: 638-94-8
Molecular Formula: C24H32O6
Molecular Weight: 416.51
EINECS: 211-351-6
Assay: 99.5%
Melting point: 272-274°C
Storage temp.: Refrigerator
Appearance: White powder
Product Categories: Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;Steroids;SPORANOX;Hormone Drugs.
Usage: 
(1)With acetal-based adrenal cortex hormones;
(2)Antifungal;
(3)Anti-inflammatory. Desonide has also been found as an impurity in budesonide (B689490).
How to use desonide topical: Use this medication only on the skin.
 
Desonide Description:
 
Desonide Ointment, 0.05% contains Desonide (Pregna - 1,4 - diene - 3,20 - dione,11,21 - dihydroxy - 16,17 - [(1 - methylethylidene)bis(oxy)] - ,(11β,16α)) a synthetic corticosteroid for topical dermatologic use. The corticosteroids constitute a class of primary synthetic steroids used topically as anti-inflammatory and antipruritic agents.
 
Chemically, Desonide, the active ingredient in Desonide Ointment, 0.05% is C24H32O6. It has the following structural formula:
 
The molecular weight of Desonide is 416.51. It is a white to off-white powder. The solubility of Desonide in distilled water saturated with ether is 184 mg/L.
Each gram of Desonide Ointment, 0.05% contains 0.5 milligram of Desonide microdispersed in a base of white petrolatum.
 
Desonide Application:
 
Desonide belongs to the group of medications known as topical corticosteroids. It is used to Treat various skin conditions, including rashes. It works by reducing inflammation and itching.
 
Endogenous eczema clinical cure rate, the overall curative effect is distinct, and the low Incidence of adverse reactions, is a safe and effective external cortex hormone.
 
Wash your hands. Before applying the medication, clean and dry the affected area. Apply a thin film of the medication to the affected area and gently rub in, usually 2-3 times daily, or as directed by your doctor. If using the gel, apply the gel usually only 2 times daily. Do not bandage, wrap, or cover the area unless you are instructed to do so by your doctor. If used in the diaper area on an infant, do not use tight-fitting diapers or plastic pants.
 
After applying the medication, wash and dry your hands, unless you are using this medication to treat the hands. When applying this medication near the eyes, avoid getting it in the eyes because this may worsen or cause glaucoma, or cause irritation. Also, avoid getting this medication in the nose or mouth. If you get this medication in your eyes, nose, or mouth, rinse immediately with plenty of water.
 

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Pharmaceutical Raw Materials Female Steroids Raw Hormone Powders Mifepristone 84371-65-3

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Pharmaceutical Raw Materials Female Steroids Raw Hormone Powders Mifepristone 84371-65-3
 
Mifepristone Basic Info.:
 
Product Name: Mifepristone (R38486)
Synonyms: 11-(4-(dimethylamino)phenyl)-17-hydroxy-17-(1-propynyl)-estra-9-dien-3-one;11beta-[4-(n,n-dimethylamino)phenyl]-17alpha-(prop-1-ynyl)-delta4,9-estradiene;r38486
CAS Number: 84371-65-3
Molecular Formula: C29H35NO2
Molecular Weight: 429.65
Assay: 99%
Melting Point: 195-198 °C
Storage temp.: 2-8°C
Appearance: Light yellowish powder
Product Categories: Steroids;Hormone;Acetylenes;Biochemistry;Functionalized Acetylenes;Hydroxyketosteroids;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;Intracellular receptor;Nuclear Receptors;Steroid and Hormone;API;Hormone Drugs.
Uses: It is a novel anti-progestin and has anti-glucocorticoid activity without the activity of progesterone, estrogen, androgen and anti-estrogen. It has a progesterone receptor affinity five times as high as progesterone. It is used for anti-pregnancy, inducing menstruation and terminating pregnancy, intrauterine inducer labor for dead fetal.
 
Mifepristone Description:
 
Mifepristone is a synthetic steroid compound with both antiprogesterone and antiglucocorticoid properties. The compound is a 19-nor steroid with substitutions at positions C11 and C17 (17 beta-hydroxy-11 beta-[4-dimethylamino phenyl] 17 alpha-[1-propynyl]estra-4, 9-dien-3-one), which antagonizes cortisol action competitively at the receptor level.
 
Mifepristone is a progesterone receptor antagonist used as an abortifacient in the first months of pregnancy, and in smaller doses as an emergency contraceptive. It is also a powerful glucocorticoid receptor antagonist.
 
Mifepristone Applications:
 
Mifepristone is used alone or in combination with misoprostol (Cytotec) to end an early pregnancy. Early pregnancy means it has been 49 days or less since your last menstrual period began. Mifepristone is in a class of medications called antiprogestational steroids. It works by blocking the activity of progesterone, a substance your body makes to help continue pregnancy.
 
Mifepristone is also available as another product (Korlym), which is used to control hyperglycemia (high blood sugar) in people with a certain type of Cushing's Syndrome in which the body makes too much of the hormone cortisol. This monograph only gives information about mifepristone (Mifeprex), which is used alone or in combination with another medication to end an early pregnancy. If you are using mifepristone to control hyperglycemia caused by Cushing's syndrome, read the monograph entitled mifepristone (Korlym) that has been written about this product.
 
Mifepristone (or RU-486) is a synthetic steroid compound with both antiprogesterone and antiglucocorticoid properties. The compound is a 19-nor steroid with substitutions at positions C11 and C17 (17 beta-hydroxy-11 beta-[4-dimethylamino phenyl] 17 alpha-[1-propynyl]estra-4, 9-dien-3-one), which antagonizes cortisol action competitively at the receptor level.
 
Mifepristone is a progesterone receptor antagonist used as an abortifacient in the first months of pregnancy, and in smaller doses as an emergency contraceptive. It is also a powerful glucocorticoid receptor antagonist, and has occasionally been used in refractory Cushing's syndrome (due to ectopic/neoplastic ACTH/cortisol secretion).
Mifepristone was the first antiprogestin to be developed and it has been evaluated extensively for its use as an abortifacient.
 

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Pharmaceutical Raw Materials Natural Steroid Hormones Powder Methyldienedione 5173-46-6

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Pharmaceutical Raw Materials Natural Steroid Hormones Powder Methyldienedione 5173-46-6
 
Methyldienedione Basic Info.:
 
Product Name: Methyldienedione
Alias: Estra-4,9-diene-3,17-dione
CAS register number: 5173-46-6
Molecular Formula: C18H22O2
Molecular Weight: 270.37
Melting Point: 131-134°C
Assay: 98%min
Grade: Pharmaceutical Grade
Storage: Shading, confined preservation
Packing: 1kg/foil bag. 25kg/drum
Character: White crystalline powder.
Usage: A potential metabolitie of STS 557 (Dienogest). A steroid with antiglucocorticoid activity.
 
Methyldienedione Description:
 
Estra-4,9-diene-3,17-dione is a powerful pro-steroid chemically similar to the anabolic agent Trenbolone.
When in the body, estra-4,9-diene-3,17-dione completes the conversion to Trenbolone. Trenbolone is a potent anabolic steroid, which binds to specific receptors present in reproductive tissue, muscle and fat.
 
Estra Diene Dione (estra-4,9-diene-3,17-dione) is an anabolic steroid and a precursor to Estra Diene Dione. It became a controlled substance in the US on January 4, 2010, and is classified as a Schedule III anabolic steroid under the United States Controlled Substances Act. Previous to this, it was sold as a bodybuilding supplement within the United States, and often mistakenly marketed as a prohormone for trenbolone, a veterinary steroid. Prior to its scheduling, it was part of a number of supplements that were seized during FDA enforcement for selling unapproved new drugs. The actual target steroid, Estra Diene Dione has some structural similarity to trenbolone, but lacks the 11-carbon -ene bond.
 
Methyldienedione Applications:
 
1. Protection from gynomastia,
2. Increased sex drive/libido,
3. Enhanced intensity & focus,
4. Estrogen control,
5. Positive effects on strength & lean mass.
 

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