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Acridine is an organic compound and a nitrogen heterocycle. Acridine is structurally related to anthracene with one of the central CH groups is replaced by nitrogen. It is a raw material used for the production of dyes and some valuable drugs.Acridine occurs naturally in coal tar. It is separated from coal tar by extracting with dilute sulfuric acid.Acridine combines readily with alkyl iodides to form alkyl acridinium iodides, which are readily transformed by the action of alkaline potassium ferricyanide to N-alkyl acridones.Acridine is a known human carcinogen. It causes frameshift mutations in incorporating into the DNA, and doing so creating an additional base on the opposite strand.
AlphaSan is an antimicrobial additive. It uses the power of silver to protect a wide variety of products against bacteria and other microbes.
Amikacin an aminoglycoside antibiotic used to treat different types of bacterial infections. Amikacin works by binding to the bacterial 30S ribosomal subunit, causing misreading of mRNA and leaving the bacterium unable to synthesize proteins vital to its growth. Amikacin is most often used for treating severe, hospital-acquired infections with multidrug-resistant Gram-negative bacteria such as Pseudomonas aeruginosa, Acinetobacter, and Enterobacter. Serratia marcescens and Providencia stuartii are also included in the spectrum. Amikacin can also be used to treat non-tubercular mycobacterial infections and tuberculosis when first-line drugs fail to control the infection. Amikacin may be combined with a beta-lactam antibiotic for empiric therapy for people with neutropenia and fever. Amikacin is usually used as a last-resort medication against multidrug-resistant bacteria.
Azomycin a congener of the radiosensitizing agent, misonidazole, sensitized hypoxic V79 hamster lung fibroblast cells to radiation and was cytotoxic to these cells. It is an antibiotic substance produced by an unidentified Streptomyces.
Biapenem is a new parenteral carbapenem antibacterial agent with a broad spectrum of in vitro antibacterial activity encompassing many Gram-negative and Gram-positive aerobic and anaerobic bacteria, including species producing beta-lactamases.
Cefaclor is a second-generation cephalosporin antibiotic used to treat certain infections caused by bacteria such as pneumonia and ear, lung, skin, throat, and urinary tract infections.
Cefdinir is a third-generation oral cephalosporin antibiotic sold under the brand names Cefzon and Omnicef. Cefdinir is a bacteriocidal antibiotic of the cephalosporin class of antibiotics. It can be used to treat infections caused by several Gram-negative and Gram-positive bacteria.Cefdinir is a broad-spectrum antibiotic and has been used to treat infections of the respiratory tract including pneumonia, sinusitis, and bronchitis.
Monensin, a monovalent ion-selective ionophore, facilitates the transmembrane exchange of principally sodium ions for protons. It is widely used in ruminant animal feeds.Monensin is used extensively in the beef and dairy industries to prevent coccidiosis, increase the production of propionic acid and prevent bloat.Monensin effects on Golgi apparatus are observed in cells from a wide range of plant and animal species. The action of monensin is most often exerted on the trans half of the stacked cisternae, often near the point of exit of secretory vesicles at the trans face of the stacked cisternae, or, especially at low monensin concentrations or short exposure times, near the middle of the stacked cisternae.
Neomycin is produced by Streptomyces fradiae.It is an aminoglycoside antibiotic.It is used to treatment for superficial eye infections caused by susceptible bacteria (used in combination with other antiinfectives), treatment of otitis externa caused by susceptible bacteria, treatment or prevention of bacterial infections in skin lesions, and use as a continuous short-term irrigant or rinse to prevent bacteriuria and gram negative rod bacteremia in abacteriuric patients with indwelling catheters.
Xibornol is an antibiotic. It is primarily administered to the throat.
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