Anticancer drugs used in treating malignancies cells in human body

chemical-categories

Streptozocin

Streptozocin is a naturally occurring chemical that is particularly toxic to the insulin-producing beta cells of the pancreas in mammals. It is used in medicine for treating certain cancers of the Islets of Langerhans and used in medical research to produce an animal model for Type 1 diabetes.It is an antibiotic that is produced by Stretomyces achromogenes.It is known to inhibit DNA synthesis, interfere with biochemical reactions of NAD and NADH, and inhibit some enzymes involved in gluconeogenesis. Its activity appears to occur as a result of formation of methylcarbonium ions, which alkylate or bind with many intracellular molecular structures including nucleic acids. Its cytotoxic action is probably due to cross-linking of strands of DNA, resulting in inhibition of DNA synthesis.

Properties Suppliers
Tesetaxel

Tesetaxel is a drug used in chemotherapy.

Properties Suppliers
Trofosfamide

Trofosfamide is a nitrogen mustard alkylating agent.It is an orally bioavailable oxazaphosphorine prodrug with antineoplastic activity.It is metabolized predominantly to the cyclophosphamide analogue ifosfamide (IFO), which is then metabolized by liver cytochrome P450s to the active isophosphoramide mustard (IPM).

Properties Suppliers
Vincristine Sulfate

Vincristine Sulfate a dimeric vinca alkaloid.It will bind to tubulin via a protein self association reaction and it also binds to sites at the ends of microtubules, which regulate the inhibition of tubulin dimer addition to microtubule ends.It has antimitotic and antineoplastic activities.It is a anticancer agent, microtubule disrupter and it induces apoptosis in human lymphoma cells.

Properties Suppliers
carboplatin

Carboplatin is an anticancer drug ("antineoplastic" or "cytotoxic") chemotherapy drug.  Carboplatin is classified as an "alkylating agent."

  • Carboplatin is used to treat ovarian cancer.
  • Carboplatin is also used for other types of cancer, including lung, head and neck, endometrial, esophageal, bladder, breast, and cervical; central nervous system or germ cell tumors; osteogenic sarcoma; and as preparation for a stem cell or bone marrow transplant.
  • Carboplatin is usually given by infusion into a vein (intravenous, IV).
  • Carboplatin can also be given intra-peritoneal, directly into the peritoneal cavity in the abdomen. 

Properties Suppliers
docetaxel trihydrate

Docetaxel is an anti-cancer ("antineoplastic" or "cytotoxic") chemotherapy drug.  This medication is classified as a "plant alkaloid,"

Docetaxel is

  • Approved in treatment of breast cancer, non-small cell lung cancer, advanced stomach cancer, head and neck cancer and metastatic prostate cancer.
  • Also being investigated to treat small cell lung, ovarian, bladder, and pancreatic cancers, soft tissue sarcoma and melanoma.
  • Docetaxel is given through a vein (intravenously, IV)  
  • There is no pill form of docetaxel

Properties Suppliers
gemcitabine hydrochloride

Gemcitabine is an anti-cancer ("antineoplastic" or "cytotoxic") chemotherapy drug.  Gemcitabine is classified as an antimetabolite. 

Treatment & Functions:

  • Pancreas cancer
  • Non-small cell lung cancer
  • Bladder cancer
  • Soft-tissue sarcoma
  • Metastatic breast cancer
  • Ovarian cancer

Route of Administration:

  • Gemcitabine is given by infusion through a vein (intravenously, by IV).
  • There is no pill form of Gemcitabine.

Properties Suppliers
oxaliplatin

Oxaliplatin is an anti-cancer ("antineoplastic" or "cytotoxic") chemotherapy drug.  Oxaliplatin is classified as an "alkylating agent."  

 

  • Oxaliplatin is used to treat colon or rectal cancer that has spread (metastasized), it is often given in combination with other anticancer drugs (fluorouracil and leucovorin).

 

  • It is given by infusion into the vein (intravenous, IV).
  • There is no pill form of Oxaliplatin.
  • The amount of Oxaliplatin you will receive depends on many factors, including your height and weight, your general health 

Properties Suppliers

123