chemical-categories

Pentamidine

Pentamidine is an antimicrobial medication given for prevention and treatment of Pneumocystis pneumonia (PCP) caused by Pneumocystis jirovecii, a severe interstitial type of pneumonia often seen in patients with HIV infection.It is used in treatment of pneumocystis pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects. It interferes with nuclear metabolism producing inhibition of the synthesis of DNA, RNA, phospholipids, and proteins.

Acacia gum

Halofuginone

Halofuginone is a coccidiostat used in veterinary medicine. It is a synthetic halogenated derivative of febrifugine, a natural quinazolinone alkaloid which can be found in the Chinese herb Dichroa febrifuga. It inhibits the development of T helper 17 cells, immune cells that play an important players in autoimmune disease, but it does not affect other kinds of T cells which involved in normal immune function. Halofuginone therefore has potential for the treatment of autoimmune disorders. It is also an inhibitor of collagen type I gene expression and as a consequence it may inhibit tumor cell growth.

Metronidazole

Metronidazole is a nitroimidazole antibiotic medication used particularly for anaerobic bacteria and protozoa.It is also amebicide.It is also used as a gel preparation in the treatment of the dermatological conditions such as rosacea and fungating tumours,used to treat infections of Giardia in dogs, cats, and other companion animals.It is also used to treat enteric (gi) and systemic infections.

Pyrimethamine

Pyrimethamine is a medication used for protozoal infections. It is commonly used as an antimalarial drug, and is also used, in combination with sulfadiazine, in the treatment of Toxoplasma gondii infections in immunocompromised patients, such as HIV-positive individuals.Pyrimethamine inhibits the dihydrofolate reductase of plasmodia and thereby blocks the biosynthesis of purines and pyrimidines, which are essential for DNA synthesis and cell multiplication. This leads to failure of nuclear division at the time of schizont formation in erythrocytes and liver.

Chlorproguanil

Chlorproguanil is an antimalarial drug. It acts by inhibition of dihydrofolate reductase after cytochrome P450-catalysed cyclization.

Docetaxel 99%

Docetaxel; CAS No.114977-28-5

White to off white crystalline

Specific rotation:-42~-48°

UV:λmax233nm±2mn

Related substance

Sum of impurities≤1.5%

Other single impurity≤0.5%

Impurity  A≤0.5%

Impurity  B≤0.3%

Impurity  C≤0.3%

Dichloromethane≤0.06%

N-hexane≤0.029%

Acetone≤0.5%

Methanol≤0.3%

Water≤3.0%

Sulphated ash≤0.1%

Heavy metals≤20ppm

Bacterial endotoxins＜0.03EU/mg

Assay:98.0~102.0%

Veliparib 97%

Veliparib (ABT-888) is a potential anti-cancer drug acting as a PARP inhibitor. It kills cancer cells by blocking a protein called PARP, thereby preventing the repair of DNA or genetic damage in cancer cells and possibly making them more susceptible to anticancer treatments.

Veliparib (ABT-888) is being investigated to treat squamous and non-squamous non-small cell lung cancer, BRCA breast cancer, triple negative breast cancer and ovarian cancer.

Sotagliflozin

SGLT1 / SGLT2 double inhibitor

New drugs for the treatment of diabetes

Venetoclax 98%

ABT-199, also known as venetoclax, is a small, oral chemical molecule used for the treatment of chronic lymphocytic leukemia (CLL) associated with a specific chromosomal abnormality. As a second line treatment drug of CLL, ABT-199 take effects through acting as a BH3-mimetic and inhibitor of Bcl-2 (the anti-apoptotic B-cell lymphoma-2protein), further inducing apoptosis of CLL cells but not platelets. It also has the potential for the treatment of ER-positive breast cancer.