Antiparasitic drugs highly effective, safe, cost effective drugs used in parasitic diseases treatment

chemical-categories

Veliparib 97%

Name

Veliparib

Synonyms

2-[(2R)-2-Methyl-2-pyrrolidinyl]-1H-benzimidazole-7-carboxamide

Molecular Formula

C13H16N4O

Molecular Weight

244.29

CAS Registry Number

912444-00-9

Veliparib (ABT-888) is a potential anti-cancer drug acting as a PARP inhibitor. It kills cancer cells by blocking a protein called PARP, thereby preventing the repair of DNA or genetic damage in cancer cells and possibly making them more susceptible to anticancer treatments.

Veliparib (ABT-888) is being investigated to treat squamous and non-squamous non-small cell lung cancer, BRCA breast cancer, triple negative breast cancer and ovarian cancer.

Properties Suppliers
Venetoclax 98%

Name

ABT 199;Venetoclax

Synonyms

4-[4-[[2-(4-Chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[3-nitro-4-[[(tetrahydro-2H-pyran-4-yl)methyl]amino]phenyl]sulfonyl]-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-benzamide

Molecular Formula

C45H50ClN7O7S

Molecular Weight

868.44

CAS Registry Number

1257044-40-8

ABT-199, also known as venetoclax, is a small, oral chemical molecule used for the treatment of chronic lymphocytic leukemia (CLL) associated with a specific chromosomal abnormality. As a second line treatment drug of CLL, ABT-199 take effects through acting as a BH3-mimetic and inhibitor of Bcl-2 (the anti-apoptotic B-cell lymphoma-2protein), further inducing apoptosis of CLL cells but not platelets. It also has the potential for the treatment of ER-positive breast cancer.

Properties Suppliers
fulvestrant 99% USP 99%

Fulvestrant; CAS No.129453-61-8

White crystalline powder

Water≤0.5%

Specific Rotation:+108°- +115°

Residue on ignition≤0.1%

Related Compounds

6-Keto-Fulvestrant≤0.1%

6,7-Fulvestrant≤0.1%

Fulvestrant sulfone≤0.2%

Fulvestrant extended≤0.3%

Fulvestrant sterol dimmer≤0.8%

Any individual unspecified impurity≤0.1%

Total impuritie≤1.0%

Fulvestrant A:42%-48%

Fulvestrant B:52%-58%

Assay(HPLC):97.0%-102.0%

Properties Suppliers
tamoxifen citrate 99% USP 99.5%

Tamoxifen citrate; CAS No. : 54965-24-1

White crystalline powder

Loss on drying ≤0.5%

Iron ≤0.005%

Heavy metals ≤0.001%

Total impurity ≤1.0%

Individual impurity ≤0.5%

E-isomer ≤0.3%

Residual solvents ≤0.5%

Acetone ≤0.5%

Assay: 99.0--101.0%

Properties Suppliers
trilostane cp 98.00% USP 99%

Name

Trilostane

Synonyms

(4a,5a,17b)-3,17-Dihydroxy-4,5-epoxyandrost-2-ene-2-carbonitrile

Molecular Formula

C20H27NO3

Molecular Weight

329.43

CAS Registry Number

13647-35-3

EINECS

237-133-0

White to pale white powder

Loss on drying≤0.5%

Melting point:257°C to 270°C

Specific rotation:+137° to +139

Residue on ignition≤0.10%

Related impurities≤1.0%

Residue solvent≤0.5%

Heavy metals≤20ppm

Assay≥99.0%

 

Trilostane is an inhibitor of 3β-hydroxysteroid dehydrogenase used in the treatment of Cushing's syndrome and primary hyperaldosteronism. 

Properties Suppliers

123