Blood pressure medicines used in blood pressure treamtment, related diseases

chemical-categories

Ferric Carboxymaltose USP

Product name: Ferric Carboxymaltose (Injectafer)
CAS No.: 9007-72-1
Appearance: Brown powder
It is an iron replacement product indicated for the treatment of iron deficiency anemia in adult patients who have intolerance to oral iron or have had unsatisfactory response to oral iron, salve and in adult patients with non-dialysis dependent chronic kidney disease. Injectafer is contraindicated in patients with hypersensitivity to Injectafer or any of its inactive components.

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Levoamlodipine Besylate

Levoamlodipine Besylate is used as anti-hypertension drug.

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Logimax

Logimax is a a fixed-dose, once-daily combination of the vascular selective calcium antagonist, felodipine, and the cardioselective beta-blocker, metoprolol.Logimax is used to treat high blood pressure (hypertension).

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Methyldopa

Methyldopa is an alpha-adrenergic agonist psychoactive drug used as a sympatholytic or antihypertensive. Its use is now mostly deprecated following the introduction of alternative safer classes of agents. Methyldopa is in a class of medications called antihypertensives. It works by relaxing the blood vessels so that blood can flow more easily through the body. Methyldopa is used to treat high blood pressure. Methyldopa exhibits variable absorption from the gastrointestinal tract. It is metabolized in the liver and intestines and is excreted in urine.

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Olmesartan

Olmesartan belongs to the class of medications called angiotensin II receptor blockers. It is used to reduce blood pressure by blocking the actions of a chemical (angiotensin II) that causes blood vessels to constrict or tighten. As a result, olmesartan relaxes the blood vessels. This lowers blood pressure and increases the supply of blood and oxygen to the heart. Olmesartan is used to treat mild to moderate high blood pressure.

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Omesartan

Olmesartan belongs to the class of medications called angiotensin II receptor blockers. It is used to reduce blood pressure by blocking the actions of a chemical (angiotensin II) that causes blood vessels to constrict or tighten. It is used to treat mild to moderate high blood pressure.

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Rivaroxaban

Name Rivaroxaban
Synonyms 5-Chloro-N-(((5S)-2-oxo-3-(4-(3-oxomorpholin-4-yl)phenyl)-1,3-oxazolidin-5-yl)methyl)thiophene-2-carboxamide
Molecular Formula C19H18ClN3O5S
Molecular Weight 435.88
CAS Registry Number 366789-02-8

 

 

 

4-(4-Aminophenyl)morpholin-3-one 438056-69-0
(S)-N-Glycidylphthalimide 161596-47-0
(S)-4-(4-(5-(Aminomethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one hydrochloride 898543-06-1
5-Chlorothiophene-2-carboxylic acid 24065-33-6

 

Rivaroxaban is a pure (S)-enantiomer. It is an odorless, non-hygroscopic, white to yellowish powder. Rivaroxaban is only slightly soluble in organic solvents (e.g., acetone, polyethylene glycol 400) and is practically insoluble in water and aqueous media.
Rivaroxaban, a FXa inhibitor, is the active ingredient in XARELTO Tablets. XARELTO a kind of orally anticoagulant drug which is used for the prevention of blood clots. Rivaroxaban takes effect through competitively inhibiting free and clot bound factor Xa, which is needed to activate prothrombin (factor II) to thrombin (factor IIa). The later is a serine protease that is required to activate fibrinogen to fibrin, which is the loose meshwork that completes the clotting process.

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Theobromine

Theobromine is a bitter xanthine alkaloid of the cacao, plantisomer of theophylline, as well as paraxanthine. Theobromine is the primary alkaloid found in cocoa and chocolate. Theobromine is used as a vasodilator (a blood vessel widener), a diuretic (urination aid), and heart stimulant. Theobromine is an isomer of theophylline, as well as paraxanthine. Theobromine was first discovered in 1841 in cacao beans by Russian chemist Alexander Voskresensky. Theobromine has also been used in birth defect experiments involving mice and rabbits. Theobromine is known to induce gene mutations in lower eukaryotes and bacteria. Theobromine is weaker in both its inhibition of cyclic nucleotide phosphodiesterases and its antagonism of adenosine receptors.

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Ticagrelor 99%

Name Ticagrelor
Synonyms AR-C 126532XX; AZD 6140; (1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl]amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol
Molecular Formula C23H28F2N6O4S
Molecular Weight 522.57
CAS Registry Number 274693-27-5

 

 

 

2-(((3aR,4S,6R,6aS)-6-Amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethanol (2R,3R)-2,3-dihydroxysuccinate 376608-65-0
(3aR,4S,6R,6aS)-6-Amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-ol 155899-66-4
2-(((3aR,4S,6R,6aS)-6-Amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethanol 274693-55-9
(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine (R)-2-hydroxy-2-phenylacetate 376608-71-8
(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine 220352-38-5
(1R,2S)-rel-2-(3,4-Difluorophenyl)cyclopropanamine hydrochloride 1156491-10-9
4,6-Dichloro-2-(propylthio)pyrimidin-5-amine 145783-15-9
4,6-Dichloro-5-nitro-2-(propylthio)pyrimidine 145783-14-8

 

 

Ticagrelor, a new platelet aggregation inhibitor successfully developed by AstraZeneca (U.S.), is the world’s first reversible combination orally-administered P2Y12 adenosine diphosphate receptor antagonist.
It is used to reduce cardiovascular death and heart attacks in patients with acute coronary syndrome (ACS.) Rapid onset after oral administration, and can effectively improve symptoms of patients with ACS. Thienopyridin

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Tranexamic Acid

Tranexamic acid is a synthetic derivative of the amino acid lysine. It is used to treat or prevent excessive blood loss during surgery and in various other medical conditions. It is an antifibrinolytic that competitively inhibits the activation of plasminogen to plasmin, by binding to specific sites of both plasminogen and plasmin, a molecule responsible for the degradation of fibrin. Tranexamic acid is frequently used in surgeries with high risk of blood loss such as cardiac, liver, vascular and large orthopedic procedures. Its oral form is now being evaluated for use in outpatient conditions involving heavy bleeding. Tranexamic acid competitively inhibits activation of plasminogen (via binding to the kringle domain), thereby reducing conversion of plasminogen to plasmin. Tranexamic acid also directly inhibits plasmin activity, but higher doses are required than are needed to reduce plasmin formation.

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