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Magaldrate is a common antacid drug that is used for the treatment of duodenal and gastric ulcers.
Sofosbuvir is a medication used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir, or daclatasvir.Sofosbuvir is a substrate of P-glycoprotein, a transporter protein that pumps drugs and other substances from intestinal epithelium cells back into the gut.Sofosbuvir inhibits the hepatitis CNS5B protein.Sofosbuvir appears to have a high barrier to the development of resistance.
Artemisinin and its derivatives are a group of drugs that possess the most rapid action of all current drugs against falciparum malaria. Treatments containing an artemisinin derivative (artemisinin-combination therapies, ACTs) are now standard treatment worldwide for falciparum malaria. Artemisinin is undergoing early research and testing for the treatment of cancer, Chinese scientists have shown artemisinin has significant anticancer effects against human hepatoma cells.
Clotiazepam is a thienodiazepine drug which is a benzodiazepine analog.
Pravastatin is a member of the drug class of statins, used for lowering cholesterol and preventing cardiovascular disease.
Trabectedin is an anti-tumor chemotherapy drug.
8-Azaguanine is a purine analog. It functions as an antimetabolite and is easily incorporated into ribonucleic acids. It shows antineoplastic activity and has been used in the treatment of acute leukemia. 8-Azaguanine was the first purine analogue discovered to inhibit experimental tumors in mice.
9-Fluorenone is used to make antimalaria drugs.
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Nitazoxanide is a broad-spectrum antiparasitic and broad-spectrum antiviral drug that is used in medicine for the treatment of various helminthic, protozoal, and viral infections.
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