Cardiovascular drugs used in cardiovascular diseases treatment heart attack, stroke, hypertension


Sitagliptin phosphate

Sitagliptin phosphate[654671-78-0]

CAS: 654671-78-0
MF: C16H15F6N5O.H3PO4
MW: 505.31




Sitagliptin phosphate is dipeptidyl peptidase Ⅳ(DDP-4) inhibitor class of drugs developed by the German Merck company and firstly obtained the US Food and Drug Administration approval for the treatment of type 2 diabetes, is a new antidiabetic drug, can improve the body's own ability to reduce high blood glucose levels, and the relatively increase naturally occurring incretin by inhibiting the activity of this enzyme, including the levels of glucagon-like peptide 1 and glucose-dependent insulinotropic peptide, thereby triggering the pancreas to improve insulin production and stop glucose production in liver, and ultimately reduce the clinical effect of blood glucose concentration. Features of this product is to stimulate insulin secretion, at the same time can alleviate hunger, but does not make weight gain, and also cannot happen hypoglycemia and edema, is not suitable for use in diabetic patients with poor glycemic control and often developed hypoglycemia.

Trelagliptin succinate

Name Trelagliptin succinate
Synonyms SYR 111472 succinate; SYR 472
Molecular Formula C18H20FN5O2.C4H6O4
Molecular Weight 475.47
CAS Registry Number





Trelagliptin 865759-25-7
2-((6-chloro-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-4-fluorobenzonitrile 865759-24-6
3-Methyl-6-chlorouracil 4318-56-3
(R)-(-)-3-Aminopiperidine dihydrochloride 334618-23-4

Propranolol Hydrochloride

Propranolol is belongs to a group of medications known as beta-blockers and is used in the treatment of high blood pressure and other conditions. In patient with high blood pressure, the blood places an abnormally high amount of force on blood vessel walls as it pumps throughout the body. This places extra strain on the heart and forces it to work harder.Symptoms of overdose include bradycardia, cardiac failure, hypotension, and brochospasm. LD50=565 mg/kg (orally in mice).

Properties Suppliers
Enoxaparin Sodium USP 95%

Enoxaparin Sodium is a kind of low molecular weight heparin sodium salt,heparin sodium was benzyl esterized and product was depolymerized under basic condition in the end resulted in Enoxaparin Sodium.Now available information show that majority of the components have a 4-enoxpyranose structure at the end of undergraded chain,15%-25% of the component has a 1,6 anhydride at he end of the degraded chain.

Enoxaparin Sodium is the sodium salt of a depolymerized heparin. It is obtained by alkaline depolymerization of heparin benzyl ester. The starting material, heparin, is obtained exclusively from porcine intestinal mucosa. Enoxaparin Sodium consists of a complex set of oligosaccharides that have not yet been completely characterized.
The weight-average molecular weight of Enoxaparin Sodium is 4,500 Da, the range being between 3,800 and 5,000 Da; about 16 percent have a molecular weight of less than 2,000 Da, the range being between 12.0 and 20.0 percent; about 74 percent have a molecular weight between 2,000 and 8,000 Da, the range being between 68.0 and 82.0 percent. Not more than 18.0 percent have a molecular weight higher than 8,000 Da. When prepared as a solution, the solution is analyzed for clarity and degree of color using a validated method. The degree of sulfation is not less than 1.8 per disaccharide unit. It has a potency of not less than 90 and not more than 125 Anti-Factor Xa International Units (IU) per mg, and not less than 20.0 and not more than 35.0 Anti-Factor IIa IU per mg, calculated on the dried basis. The ratio of anti-factor Xa activity to anti-factor IIa activity is between 3.3 to 5.3.

Storage:Sealed,avoid light and oxygen resistant.

Enoxaparin sodium is a blood thinner. It used to treat and prevent deep vein thrombosis and pulmonary embolism including during pregnancy. It is also used in those with acute coronary syndrome and heart attacks.Other uses include insidekidney dialysis machines.

Buflomedil hydrochloride 98%


Buflomedil hydrochloride


1-[3-(2,4,6-Trimethoxybenzoyl)propyl]pyrrolidinium chloride

Molecular Formula


Molecular Weight


CAS Registry Number




Buflomedil is used as an vasodilator (peripheral).


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