Cardiovascular drugs used in cardiovascular diseases treatment heart attack, stroke, hypertension


Isosorbide Dinitrate

Isosorbide Dinitrate is a moderate to long acting oral organic nitrate used for the relief and prophylactic management of angina pectoris. It relaxes the vascular smooth muscle and consequent dilatation of peripheral arteries and veins. It is also used as a direct vasodilator to treat congestive heart failure. It relaxes blood vessels, increasing the blood and oxygen supply to heart. It relieves the pain you can get with angina. Isosorbide dinitrate can also help to prevent pain before activities that can cause an attack.

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Lisinopril Dihydrate

Lisinopril Dihydrate is an angiotensin converting enzyme (ACE) inhibitor for hypertension, congestive heart failure, acute myocardial infarction, and renal complications of diabetes mellitus.

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Metoprolol Succinate

Metoprolol Succinate is a cardioselective beta-blocker for hypertension, angina pectoris, heart failure, disturbances of cardiac rhythm including supraventricular tachycardia, maintenance treatment after myocardial infarction and functional heart disorders with palpitations and for migraine prophylaxis. It is used in the following products; Seloken ZOK, Toprol-XL and Betaloc ZOK.

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Candesartan Cilexetil

Candesartan Cilexetil is a prodrug, is hydrolyzed to candesartan during absorption from the gastrointestinal tract. Candesartan Cilexetil is rapidly and completely bioactivated by ester hydrolysis during absorption from the gastrointestinal tract to candesartan, a selective AT1 subtype angiotensin II receptor antagonist. Candesartan Cilexetil is a drug used for treating high blood pressure (hypertension). It is in a class of drugs called angiotensin receptor blockers (ARBs) and indicated for the treatment of patients with hypertension and patients with chronic heart failure(CHF) and left ventricular systolic dysfunction.

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Heparin Sodium USP 95%

Heparin Sodium is the sodium salt of sulfated glycosaminoglycans and is present as a mixture of heterogeneous molecules varying in molecular weights that work against different factors of the blood clotting spectrum. It is obtained from porcine intestinal mucosa.Heparin Sodium is composed of polymers of alternating derivatives of α-D-glucosamido (N-sulfated, O-sulfated, or N-acetylated) and O-sulfated uronic acid (α-L-iduronic acid or β-D-glucuronic acid). The component activities of the mixture are in ratios corresponding to the USP specification. These components have the property of prolonging the clotting time of blood. This occurs mainly through the formation of a complexity of each component with the plasma proteins antithrombin and heparin cofactor II to potentiate the inactivation of thrombin (factor IIa). Other coagulation proteases in the clotting sequence, such as activated factor X (factor Xa), are also inhibited.

Heparin Sodium is a naturally-occurring anticoagulant used for anticoagulation for Cardiovascular Disease.Heparin Sodium Salt is widely used as an injectable anticoagulant. It can also be used to form an inner anticoagulant surface on various experimental and medical devices such as test tubes and renal dialysis machines.

Heparin sodium, is a kind of acid mucopolysaccharides an anti clotting drug, on a number of links in coagulation process to intervene, prolonged clotting time and thrombin time. And the application range is not limited to in vivo, in vitro threw a good anticoagulant effect, by fibrin, inhibiting platelet aggregation.

Heparin Sodium also can be used in cosmetic industry. Heparin sodium can be used as a hair tonic, nourishing cream acne products, eye cream, cosmetics raw materials. It can be added to the nutritional cream, eye cream, acne products and hair agent and other cosmetics to increase skin vascular permeability, improve the role of local vascular circulation, promote the supply of skin nutrition and the excretion of metabolic waste,Health care and skin care.

Isosorbide Mononitrate

Isosorbide mononitrate is a drug used principally in the treatment of angina pectoris, hypertension, and myocardial infarction and acts by dilating the blood vessels so as to reduce the blood pressure. It is an active metabolite of isosorbide dinitrate and exerts qualitatively similar effects. Isosorbide mononitrate reduces the workload of the heart by producing venous and arterial dilation. Isosorbide mononitrate is primarily metabolized by the liver, but unlike oral isosorbide dinitrate. It is cleared by denitration to isosorbide and glucuronidation as the mononitrate, with 96% of the administered dose excreted.

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Testosterone Enanthate

Testosterone Enanthate is one of the oldest forms of testosterone ever made available and is further by-in-large the most popular and commonly used testosterone. Testosterone enanthate heals the damaged cells of the body, thanks to the fact that it increases the activity of satellite cells that promotes healing. Testosterone enanthate has the ability to guard your body against coronary heart disease that comes because of bad cholesterol, by reducing bad cholesterol. Testosterone enanthate is popular among athletes and bodybuilders because promotes protein synthesis leading to muscle hypertrophy and muscle hyperplasia, the two different but equally important processes in muscle growth.

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Betaxolol Hydrochloride

Betaxolol Hydrochloride is a competitive, beta(1)-selective (cardioselective) adrenergic antagonist.It is selectively blocks catecholamine stimulation of beta(1)-adrenergic receptors in the heart and vascular smooth muscle and results in a reduction of heart rate, cardiac output, systolic and diastolic blood pressure, and possibly reflex orthostatic hypotension.It can also competitively block beta(2)-adrenergic responses in the bronchial and vascular smooth muscles, causing bronchospasm.It is used to treat hypertension, arrhythmias, coronary heart disease, glaucoma, and is also used to reduce non-fatal cardiac events in patients with heart failure.

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Bisoprolol Hemifumarate

Bisoprolol Hemifumarate is an selective β1-adrenergic antagonist. Bisoprolol Hemifumarate is used to treat hypertension, arrhythmias, coronary heart disease, glaucoma, etc. and is also used to reduce non-fatal cardiac events in patients with heart failure.

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Diltiazem Hydrochloride

Diltiazem Hydrochloride is an antihypertensive and cardioprotective agent as well as a calcium channel protein inhibitor. Diltiazem Hydrochloride inhibits L-type Ca2+ channels and regulates Ca2+ release from intracellular stores in neutrophils.

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