Dermatological drugs pharmaceuticals used in treating skin diseases


Acacia gum

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Acitretin is a second generation retinoid. It is a metabolite of etretinate.It is taken orally, and is typically used for psoriasis.Acitretin works by inhibiting the excessive cell growth and keratinisation (process by which skin cells become thickened due to the deposition of a protein within them) seen in psoriasis. It therefore reduces the thickening of the skin, plaque formation and scaling.

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Adapalene is a third-generation topical retinoid.It is primarily used in the treatment of mild-moderate acne and is also used to treat keratosis pilaris as well as other skin conditions,topical treatment of comedo, papular and pustular acne (acne vulgaris) of the face, chest or back.Adapalene in small concentrations is a moderator of cellular differentiation, keratinization, and inflammatory processes. It has both exfoliating and anti-inflammatory effects.

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Chlorphenesin Carbamate

Chlorphenesin is a centrally acting muscle relaxant used to treat muscle pain and spasms. It also has antifungal and some antibacterial properties and is thus classified as an antifungal for topical use by the WHO.

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Clindamycin is a lincosamide antibiotic. It is usually used to treat infections with anaerobic bacteria but can also be used to treat some protozoal diseases, such as malaria. It is a common topical treatment for acne and can be useful against some methicillin-resistant Staphylococcus aureus infections. The veterinary uses of clindamycin are quite similar to its human indications, and include treatment of osteomyelitis, skin infections, and toxoplasmosis, for which it is the preferred drug in dogs and cats.

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Clobetasol Propionate

Clobetasol propionate is a corticosteroid. It used to treat various skin disorders including eczema and psoriasis. It is also highly effective for contact dermatitis. It is also used to treat several auto-immune diseases including alopecia areata, vitiligo and lichen planus, mycosis fungoides (T-cell skin lymphoma).

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Clocortolone Pivalate

Clocortolone pivalate is a mid-potency corticosteroid cream for the treatment of inflammation and itching effective in treating stasis dermatitis, eczema/atopic dermatitis, contact dermatitis and seborrhea.

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Cyclosporine is a cyclic undecapeptide from an extract of soil fungi. It is a powerful immunosupressant with a specific action on T-lymphocytes. It is used for the prophylaxis of graft rejection in organ and tissue transplantation.Cyclosporine binds to cyclophillin. The complex then inhibits calcineurin which is normally responsible for activating transcription of interleukin 2. Cyclosporine also inhibits lymphokine production and interleukin release. Cyclosporine emulsion is thought to act as a partial immunomodulator in patients whose tear production is presumed to be suppressed due to ocular inflammation associated with keratoconjunctivitis sicca.

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Dicloxacillin Sodium

Dicloxacillin Sodium is an oral semisynthetic isoxazolyl antistaphylococcal penicillin. It is stable against penicillinase.It is active against many of the penicillinase-producing strains of Staphylococcus aureus, and is used mainly in the treatment of infections caused by these organisms. It is the most active of the isoxazolyl antistaphylococcal penicillins. It is used to skin and soft-tissue infections, bone and joint infections, and urinary and respiratory tract infections.

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Etretinate is a medication used to treat severe psoriasis. It is a synthetic aromatic retinoid.It is an aromatic retinoid, and therefore highly lipophilic. It is stored and released from adipose tissue, so its effects can continue long after dosage stops. It is detectable in the plasma for up to three years following therapy.Etretinate is now used to treat T-cell lymphomas.

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