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Gephyrotoxin is a naturally occurring product that stems from the Colombian tropical frog Dendrobates histrionicus. It is a member of the class of compounds known as histrionicotoxins. This alkaloid skin secretion was first isolated from the tropical frog in 1977 by Daly and his fellow workers.

Globoidnan A

Globoidnan A is a lignan found in Eucalyptus globoidea. The molecule has been found to inhibit the action of HIV integrase, an enzyme which is responsible for the introduction of HIV viral RNA into a host's cellular DNA.


Glycyrrhizin is the main sweet-tasting compound from liquorice root. It is 30 to 50 times as sweet as sucrose. Chemically, glycyrrhizin is a triterpenoid saponin glycoside of glycyrrhizic acid. Upon hydrolysis, the glycoside loses its sweet taste and is converted to the aglycone glycyrrhetinic acid plus two molecules of glucuronic acid. Although sweet, the taste sensation of glycyrrhizin is different from that of sugar. The sweetness of glycyrrhizin has a slower onset than sugar, and lingers in the mouth for some time. Unlike the artificial sweetener aspartame, glycyrrhizin maintains its sweetness under heating. Glycyrrhizin is used as a flavoring in some candies, pharmaceuticals, and tobacco products.

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Hasubanonine is a member of the hasubanan family of alkaloids. The enantiomer of the natural product is being studied as a potential painkiller.


Hernandaline is one of a class of quinoline alkaloids. This compound has been isolated from the stem bark of Hernandia ovigera.

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