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Anatabine is one of the minor alkaloids found in plants in the Solanaceae family, which includes the tobacco plant, that has been shown to affect monoamine oxidase activity. It is found in cigarette tobacco and smoke, and is absorbed in the human body after tobacco use. It is currently being used as one of the active dietary ingredients in the smoking alternative dietary supplement product, CiGRX, developed by Rock Creek Pharmaceuticals. The use of anatabine rather than nicotine replacement therapy is related to the half-lives of nicotine and anatabine. The Roskamp Institute is testing anatabine's potential in fighting Alzheimer's disease and other anti-inflammatory illnesses.

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