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Asenapine

Asenapine is a new atypical antipsychotic developed for the treatment of schizophrenia and acute mania associated with bipolar disorder by Schering-Plough. Preliminary data indicate that it has minimal anticholinergic and cardiovascular side effects, as well as minimal weight gain.

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Aspartame

Aspartame is an artificial, non-saccharide sweetener used as a sugar substitute in some foods and beverages. It is a white, odourless powder, approximately 200 times sweeter than sugar, manufactured by combining phenylalanine and aspartic acid. Its main impurity is diketopiperazine that has no sweetening properties. It is not only used in food but also in pharmaceutical also.

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Auraptene

Auraptene is a natural bioactive monoterpene coumarin ether. It was first isolated from members of the genus Citrus. It has shown a remarkable effect in the prevention of degenerative diseases. Many studies have reported the effect of auraptene as a chemopreventative agent against cancers of liver, skin, tongue, esophagus, and colon in rodent models. The effect in humans is not yet known.

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Axillarin

Axillarin is an O-methylated flavonol.

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Azaleatin

Azaleatin is a chemical compound. It is an O-methylated flavonol, a type of flavonoid. It was first isolated from the flowers of Rhododendron mucronatum in 1956.

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Azetidine

Azetidine is a heterocyclic organic compound. It belongs to the class of four membered rings and it contains a nitrogen atom.

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Baicalein

Baicalein is a flavone, a type of flavonoid, originally isolated from the roots of Scutellaria baicalensis. It is the aglycone of baicalin. The flavonoid has been shown to inhibit certain types of lipoxygenases and act as an anti-inflammatory agent. It is an inhibitor of CYP2C9, an enzyme of the cytochrome P450 system that metabolizes drugs in the body. Baicalin is a known prolyl endopeptidase inhibitor.

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Barbinine

Barbinine is a diterpene alkaloid that is a phytotoxin produced by several Delphinium species.

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Benzamide

Benzamide is a derivative of benzoic acid. It is the most potent poly(ADP-ribose) polymerase (PARP) inhibitor in the family of benzamides. It acts as a neuroprotectant since it inhibits PARP, an enzyme activated by nitric oxide. It is twice as active as its commonly used counterpart, 3-aminobenzamide, in delaying or suppressing PARP activation. The actions of benzamide prevent nuclear fragmentation and apoptotic-body formation without affecting DNA fragmentation during apoptosis.

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