chemical-categories

 

99% Purity Steroids Arimidex 120511-73-1 Anastrozole For Women Breast Cancer

 

Anastrozole Basic Info.:

 

Product Name: Anastrozole

Synonyms: Anastrozole;Arimidex

CAS No: 120511-73-1

Molecular formula: C17H19N5

Molecular weight: 293.37

Appearance: White powder.

Assay: 99%

Melting point: 81-82°C

Storage temp.: Store at RT

Minimum order: 10g

Quality standard: USP 32 

 

Anastrozole Descriptions:

 

Anastrozole will begin taking it the day they start their cycle, Anastrozole will run it throughout the duration of steroid administration. Anastrozole is also important to point out GP Anastrozole's ability to increase testosterone in the body. Some studies have shown that natural testosterone levels have increases as much as 60% after the use of this substance for 7 days. Because of this, bodybuilders find Anastrozole extremely effective during PCT where as they are trying to elevate natural levels as much as possible in order to avoid a post cycle "crash".

 

Anastrozole Applications:

 

High Purity Anastrozole/Arimidex/CAS No: 120511-73-1

The drug is appropriately used when using substantial amounts of aromatizing steroids, or when one is prone to gynecomastia and using moderate amounts of such steroids. Arimidex does not have the side effects of aminoglutethimide (Cytadren) and can achieve a high degree of estrogen blockade, much moreso than Cytadren. It is possible to reduce estrogen too much with Arimidex, and for this reason blood tests, or less preferably salivary tests, should be taken after the first week of use to determine if the dosing is correct.

 

 

Effective Legal Muscle Building Steroids Hormone Powder Mebolazine 3625-07-8

 

Mebolazine Basic Info.

 

Product Name: Mebolazine

Alias: Mebolazine; Diarethyl; Dimetazin; Dimetina; Dostalon; Roxilon; 2-alpha-Dimethyl-5-alpha-androstan-17-beta-ol-3

CAS No.: 3625-07-8

Molecular Formula: C42H68N2O2

Molecular Weight: 633.011

EINECS: 214-983-0

Density: 1.24

Purity: ≥99%

Appearance: White Powder

Usage: Diamethazine is an C17-alkylated, anabolic-androgenic steroid, that exhibits similar effects to Superdrol (M226010).

 

Mebolazine Description:

 

Mebolazine is really a variant of the Superdrol molecule with almost the exact same features. It is really just two superdrol molecules paired together and those molecules break apart in the body to form two Superdrol molecules.

 

Mebolazine is very similar in effects to Superdrol, but may be slightly milder on the liver, due to the bonding. No one knows where the molecule actually splits, so it is possible that the molecule makes it past the liver and misses the first pass, thus making it less liver stressful. That being said, Mebolazine has just about the same characteristics as superdrol, meaning it will likely be very supressive to natural androgen production and can’t convert to estrogen, making the need to stack it with something “wet” pretty common.

 

Mebolazine should have the same harsh effects on cholesterol and blood pressure as Superdrol, since it is a DHT compound that is very dry. Common side effects will be similar like extreme back pumps, the ability to gain 15-18lbs of dry mass in a 3 week period, aggressive moods and acne.

 

Mebolazine Application:

 

Dymethazine is really a variant of the Superdrol molecule with almost the exact same features. It is really just two superdrol molecules paired together and those molecules break apart in the body to form two Superdrol molecules.

 

Dymethazine is very similar in effects to Superdrol, but may be slightly milder on the liver, due to the bonding. No one knows where the molecule actually splits, so it is possible that the molecule makes it past the liver and misses the first pass, thus making it less liver stressful.

 

That being said, Dymethazine has just about the same characteristics as superdrol, meaning it will likely be very supressive to natural androgen production and can't convert to estrogen, making the need to stack it with something "wet" pretty common.

 

Dymethazine should have the same harsh effects on cholesterol and blood pressure as Superdrol, since it is a DHT compound that is very dry. Common side effects will be similar like extreme back pumps, the ability to gain 15-18lbs of dry mass in a 3 week period, aggressive moods and acne.

 

 

High Purity 99.5% Tetracaine White Fine Powder For Local Anaesthesia 94-24-6

 

Tetracaine Basic Info.:

 

Product Name: Tetracaine

Synonym: Anetain, Amethocaine, Pontocaine,Ametop,Dicaine

CAS: 94-24-6

MF: C15H24N2O2

MW: 264.36

EINECS: 202-316-6

Assay: 99%

Quality Standards: EnterpriseStandard/Pharma Grade

Appearance: White powder

Package: 25kg/Drum

Usage: Tetracaine is a topical local anesthetic for the eyes. Tetracaine works by interfering with entry of sodium ions into nerve cells. This reduces the ability of nerves to generate an impulse and send pain sensations.

 

Tetracaine Description:

 

Tetracaine (INN, also known as amethocaine; trade name Pontocaine. Ametop and Dicaine) is a potent local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia. It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.

(1) In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.

(2) Tetracaine is the T in Tac, a mixture of 5 to 12 per cent tetracaine, 5M(per myriad), a half per mille (0.5‰), or .05 per cent (1 part in 2000) , and 4 or 10 per cent hydrochloride used in ear, nose & throat surgery and in the emergemcy department where numbing of the surface is needed rapidly, especially when children have been injured in the eye, ear, or other sensitive locations.

(3) Tetracaine is synthesized from 4-butylaminobenzoic acid. The ethyl ester is formed through an acid-catalyzed esterification reaction. Base-catalyzed transesterification is achieved by boiling the ethyl ester of 4-butylaminobenzoic acid with excess 2-dimethylaminoethanol in the presence of a small amount of sodium ethoxide.

 

Tetracaine Applications:

 

Tetracaine is used in different parts of the body to cause numbness or loss of feeling in some patients before having a medical test or procedure.

 

 

Human Growth Hormone Active Pharmaceutical Ingredient Gonadorelin 33515-09-2

 

Gonadorelin Basic Info.:

 

Product Name: Gonadorelin

Other Name: LH-RH, human, Gonadoreline

CAS: 33515-09-2

Purity (HPLC): 98.0%min.

Appearance: White powder

Molecular Formula: C59H83N17O17

Molecular Weight: 1302.39

Single Impurity (HPLC): 0.5%max

Amino Acid Composition: ±10% of theoretical

Peptide Content (N%): ≥80.0% 

Water Content(Karl Fischer): ≤8.0%

Acetate Content(HPIC): ≤10.0%

Specific Rotation (20/D): -55.0~-65.0°(c=1 1%HAc)

MS (ESI): Consistent

Mass Balance: 95.0~105.0%

 

Gonadorelin Description:

 

Gonadorelin is another name for gonadotropin-releasing hormone (GnRH). It is a synthetic decapeptide prepared using solid phase peptide synthesis. GnRH is responsible for the release of follicle stimulating hormone and leutinizing hormone from the anterior pitutitary.

GnRH is available as gonadorelin hydrochloride(Factrel®)and gonadorelin diacetate tetrahydrate(Cystorelin®)for injectable use. Studies have described it being used via an infusion pump system to induce ovulation in patients with hypothalamic hypogonadism. It is also used in veterinary medicine as a treatment for cattle with cystic ovarian disease.

 

Gonadorelin Application:

 

Gonadorelin is responsible for the release of follicle stimulating hormone and leutinizing hormone from the anterior pitutitary. In the pituitary GnRH stimulates synthesis and release of FSH and LH, a process that is controlled by the frequency and amplitude of GnRH pulses, as well as the feedback of androgens and estrogens. The pulsatility of GnRH secretion has been seen in all vertebrates, and it is necessary to ensure a correct reproductive function. Thus a single hormone, GnRH, controls a complex process of follicular growth, ovulation, and corpus luteum maintenance in the female, and spermatogenesis in the male. Its short half life requires infusion pumps for its clinical use.

 

 

Oral Finasteride / Proscar Steroids Powder For Hairloss Treatment 98319-26-7

 

Finasteride Basic Info.

 

Product Name: Finasteride

Synonyms: Finasteride;Proscar;Prostide;

CAS: 98319-26-7

Molecular Formula: C23H36N2O2

Molecular Weight: 372.5441

Assay: 99%

Appearance: White or off-white crystal powder

Density: 1.066g/cm3

Boiling Point: 576.61°C at 760 mmHg

Flash Point: 177.448°C

Vapour Pressure: 0mmHg at 25°C

Usage: It is 5 alpha - reductase inhibitor that can inhibit testosterone to convert into DHT. Also used for the treatment of Hyperplasia of prostate. Finasteride is a 4-- aza-steroid compound which is a specific inhibitor of the metabolism of testosterone within dihydro testosterone become stronger during the cell type-II enzyme 5a-reductase. The enlarged prostate called benign prostatic hyperplasia or prostate depends on the conversion of testosterone to dihydro-testosterone.

 

Finasteride Description:

 

Finasteride is a popular anti-androgen medication manufactured by Merck most commonly known as either Proscar or Propecia. Based on the progesterone skeleton, Finasteride belongs to a class of medications known as 5alpha-reductase inhibitors and as such is used for the treatment revolving around type 2 5-AR based occurrences.

 

This is important for performance enhancers as DHT based anabolic steroids have specific side-effects that may occur that can largely be remedied with the use of a 5-AR inhibitor such as Finasteride. As a type 2 5-AR inhibitor Finasteride was designed for the purpose of treating hair-loss, prostate enlargement, as well as prostate cancer.

 

Finasteride is very common among those who supplement with anabolic steroids yet fear hair-loss but there are important things you need to understand before you consider Finasteride use. As an androgen suppressor Finasteride can seriously inhibit the gains made while on cycle, severely and on that basis it is not highly recommended for on-cycle hair preservation.

 

Finasteride Applications:

 

Propecia (finasteride) is used to treat male pattern baldness (androgenic alopecia) in men. Oral use though will reduce DHT levels systemically, which may adversely affect training and sex drive.

 

It is also used in combination with doxazosin in the treatment of benign prostatic hyperplasia (BPH).] Finasteride is an orally active testosterone Type II 5-alpha reductase inhibitor, inhibiting the enzyme that converts testosterone to dihydrotestosterone (DHT).

Topically (on the scalp itself) it is of some effect in minimizing further hair loss. In combination with Nizoral and spironolactone (which smells awful, by the way) it can actually reverse loss moderately.

 

For use in cycles with testosterone, I don't think it is bad at all. One simply doesn't want less DHT than normal. As the amount of testosterone in the system increases, the amount of finasteride needed to keep levels down to normal increases. I consider 5 mg/day reasonable at the gram per week level, and proportionally less at lower dosages of testosterone.

 

 

Pharmaceutical Grade Reducing Fat Mass Chemicals Sr9011 SR-9011 1379686-29-9

 

SR9011 Basic Info:

 

Product Name: SR9011

Synonyms: 3-(((4-chlorobenzyl)((5-nitrothiophen-2-yl)methyl)amino)methyl)-N-pentylpyrrolidine-1-carboxamide

CAS No: 1379686-29-9

Molucelar Formula: C23H31ClN4O3S

Molucelar Weight: 479.03524

Solubility: DMSO up to 100 mM

 

Sr9011 Description:

 

SR9011 is a trifunctional methacrylate monomer that provides exceptional adhesion to metal substrates.

SR9011 is recommended for use in peroxide cured coatings, sealants, and PVC-based plastisols. Usage levels of 5% to 10% by weight are recommended.

 

SR9011 is a potent and specific synthetic REV-ERB agonist that binds to REV ERB α with an EC50 ~790 nM and REV-ERB-β with EC50 ~560 nM. It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB-α and REV-ERB-β play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism. Administration of SR9011 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice. The circadian expression pattern of an array of metabolic genes in the liver, skeletal muscle and adipose tissue was also altered, resulting in increased energy expenditure. Treatment of diet induced obese mice with SR9011 decreased obesity by reducing fat mass and markedly improved dyslipidaemia and hyperglycaemia. These results indicate that synthetic REV-ERB ligands that pharmacologically target the circadian rhythm may be beneficial in the treatment of sleep disorders as well as metabolic diseases.

 

Sr9011 Application:

 

In vitro: SR9011 was used at 5-10 μM concentration in vitro and in cellular assays.

In vivo: IP administration of SR9011 was used at 100 mg/kg once or twice per day for 12-30 days in different mouse models.

 

 

Tacrolimus FK-506 Pharmaceutical Intermediates Organ Transplant  104987-11-3

 

Tacrolimus Basic info: 

 

Product Name: Tacrolimus

Synonyms: Tacrolimus;Fr900506;Prograf;Tsukubaenolide;FK-506;

CAS: 104987-11-3

MF: C44H69NO12

MW: 804.02

Purity: 99%

Melting Point: 113-115°C

Boiling Point: 871.7 °C at 760 mmHg

Solubility: DMSO: >3 mg/mL

Appearance: White Crystalline Powder

Storage temp.: −20°C

Storage: Store in a cool, dry place. Do not store in direct sunlight. Store in a tightly closed container.

Product Categories: Active Pharmaceutical Ingredients;Immunosuppressant.;Intermediates & Fine Chemicals;Pharmaceuticals;API;Chiral Reagents;Fujimycin, Prograf;antibiotic;Inhibitors.

Usage: FK-506 (Tacrolimus) is a macrolide immunosuppressive drug that is mainly used after allogeneic organ transplant to reduce the activity of the patient's immune system.

 

Tacrolimus Application: 

 

L Immunosuppression following transplantation It has similar immunosuppressive properties to ciclosporin, but is much more potent. Immunosuppression with tacrolimus was associated with a significantly lower rate of acute rejection compared with ciclosporin-based immunosuppression (30.7% vs 46.4%) in one study. Clinical outcome is better with tacrolimus than with ciclosporin during the first year of liver transplantation. Long term outcome has not been improved to the same extent. Tacrolimus is normally prescribed as part of a post-transplant cocktail including steroids, mycophenolate and IL-2 receptor inhibitors. Dosages are titrated to target blood levels. Typical starting doses for once daily tacrolimus are 0.15-0.20 mg/kg body weight.

 

Tacrolimus Interactions:

 

Also like cyclosporin it has a wide range of interactions, including that with grapefruit which increases plasma-tacrolimus concentration. Several of the newer class of antifungals, especially of the azole class (fluconazole, posaconazole) also increase drug levels by competing for degradative enzymes.

 

Ulcerative colitis: 

In recent years, tacrolimus has been used to suppress the inflammation associated with ulcerative colitis, a form of inflammatory bowel disease. Although almost exclusively used in trial cases only, tacrolimus has shown to be significantly effective in the suppression of outbreaks of UC.

 

Tacrolimus Dermatological Use: 

 

As an ointment, tacrolimus is used in the treatment of eczema, in particular atopic dermatitis. It suppresses inflammation in a similar way to steroids, and is equally as effective as a mid-potency steroid. An important advantage of tacrolimus is that, unlike steroids, it does not cause skin thinning (atrophy), or other steroid related side-effects.

 

It is applied on the active lesions until they heal off, but may also be used continuously in low doses (twice a week), and applied to the thinner skin over the face and eyelids[citation needed]. Clinical trials of up to one year have been conducted. Recently it has also been used to treat segmental vitiligo in children, especially in areas on the face.

 

 

99% High Quality Anesthetic CAS 61-12-1 Dibucaine Hydrochloride Dibucaine HCl

 

Dibucaine HCL Basic Info.:

 

Product Name: Dibucaine hydrochloride

Dibucaine hydrochloride Synonyms: 2-butoxy-n-(2-(diethylamino)ethyl)-4-quinolinecarboxamidmonohydrochlorid;butoxycinchoninicaciddiethylethylenediamidehydrochloride;c3225

CAS: 61-12-1

MF: C20H30ClN3O2

MW: 379.92

EINECS: 200-498-1

Product Categories: Heterocycles;Intermediates & Fine Chemicals;PharmaceuticalsDibucaine hydrochloride  Chemical Properties:whitepowder Dibucaine hydrochloride  Usage Anesthetic (local).

 

Dibucaine HCL Description:

 

Dibucaine hydrochloride is a local anesthetic of the amide type now generally used for surface anesthesia. It is one of the most potent and toxic of the long-acting local anesthetics and its parenteral use is restricted. The drug blocks both the initiation and conduction of nerve impulses by decreasing the neuronal membrane's permeability to sodium ions. This reversibly stabilizes the membrane and inhibits depolarization, resulting in the failure of a propagated action potential and subsequent conduction blockade.

 

In combination sodium dibucaine hydrochloride is administered to dogs to induce rapid, humane, painless euthanasia. The euthanasia solution is toxic to wildlife. Euthanized animals must be properly disposed of by deep burial, incineration or other method in compliance with state and local laws.

 

Dibucaine HCL Applications:

 

Spinal anesthesia (high, low, saddle block) and topically to produce surface anesthesia. Eye: To anesthetize conjunctiva and cornea prior to superficial procedures (including tonometry, gonioscopy, removal of foreign bodies or sutures, corneal scraping).

 

Nose and Throat: To abolish laryngeal and esophageal reflexes prior to bronchoscopy, esophagoscopy.

Skin: To relieve pruritus, pain, burning.

 

 

Body Building Anabolic Sarms LGD-4033 Purity 99% Sarms Ligandrol 1165910-22-4

 

LGD-4033 Basic Info.:

 

Product Name: LGD-4033

Synonyms: LGD-4033;LGD4033;Ligandrol;

CAS: 118237-47-0

MF: C20H16ClN5O2

MW: 393.826

Purity: 99.5%(HPLC)

Apprarance: White crystalline powder.

 

LGD-4033 Product Description:

 

LGD-4033 is a selective androgen receptor modulator (SARMS), and a novel non-steroidal oral SARM that binds to AR with high affinity (Ki of ~1 nM) and selectivity. It’s in a class of androgen receptor (AR) ligands that is tissue selective, developed to treat muscle wasting associated with cancer, acute and chronic illness and age-related muscle loss. LGD-4033 is expected to produce the therapeutic benefits of testosterone with improved safety, tolerability and patient acceptance due to tissue-selective mechanism of action and an oral route of administration.

 

LGD-4033, a novel nonsteroidal, oral selective androgen receptor modulator, binds to the androgen receptor with high affinity and selectivity. It demonstrates anabolic activity in muscles, anti-resorptive and anabolic activity in bones and a robust selectivity for muscle and bone versus prostate and sebaceous glands. LGD-4033 has recently completed a Phase I Multiple Ascending Dose study in healthy volunteers. This randomized, double-blind, placebo-controlled Phase I study established the safety and tolerability up to doses of 22 mg per day.

 

LGD-4033 Application:

 

LGD is still fairly new (3-5 years), but the results have been very similar in studies and logs. LGD-4033 has undergone several recent studies and trials to find the best and safest way to use it. From these trials, the results have shown increases in lean body mass and decreases in body fat. There is also a significant increase in strength, well being, as well as healing possibilities.

 

LGD has shown the most ability of any SARM to put on size that could be considered a bulk. This will, of course, be dependent upon the diet used. Users that have experienced more than 10lb. increases, and have had a significant increase in calorie intake. The possibility of this type of size is present with LGD use. A recommend dosage for this type of goal would be 5-10 mg day for 8 weeks.

 

LGD seems to shine with this method. Many have seen an increase in lean body mass and a decrease in body fat. LGD seems to work the best with this method. Ran in conjunction with other SARMS, like cardarine (GW-501516), will only increase the likelihood of a stronger recomp. Recommended doses for recomping would be 5-8 mg a day for 8 weeks.

 

LGD can be used to cut as well. It will shine more-so if ran in conjunction with SARMS S-4 and Cardarine (GW-501516). This would be similar to a SARMS triple stack that is normally ran with Ostarine, except there is a possibility of more size being put on while cutting. A good dose for this method would be 3-5 mg a day for 8 weeks.

 

 

Injectable Anabolic Steroid Nandrolone Cypionate For Muscle Building 601-63-8

 

Nandrolone Cypionate Basic Info.

 

Product Name: Nandrolone Cypionate

Synonyms: Nandrolone Cypionate; Nandrolone Cipionate; Nortestosterone Cypionate; Nandrolone Cypionate;Nandrolone Cyclopentanepropionate; Nandrolone Cypiontate

CAS: 601-63-8

MF: C26H38O3

MW: 398.57812

EINECS: 210-006-7

Assay: 99% 

Appearance: Pale yellow oily liquid

Product Categories: Steroid and Hormone

 

Nandrolone Cypionate Description: 

 

Nandrolone cypionate is recommended as an aid for the treatment of debilitated horses when an improvement in weight, hair coat or general physical condition is desired. Debilitation often follows disease or may occur following overwork and overexertion.

 

Nandrolone improves the general state of debilitated horses, thus aiding in correcting weight losses and improving appetite. It is not a substitute for a well-balanced diet. Optimal results can be expected only when good management and feeding practices are utilized.

 

Nandrolone should be considered only as adjunctive therapy to other specific and supportive therapy for diseases, surgical cases and traumatic injuries.

 

Testosterone Cypionate is the longest-estered testosterone available today. It has a half-life in the body of 15 to 16 days and is found as injectable oil. Because it reacts in the body for so long, it can cause more water retention than other steroids and is best used as bulking compound in a stack.

 

As with all testosterone injectables, one can expect a considerable gain in muscle mass and strength during a cycle. Since testosterone readliy converts to estrogen, the mass gained from this drug is likely to be accompanied by quite a bit of water retention. The resulting loss of definition of course makes cypionate a very poor choice for dieting or cutting phases. The excess level of estrogen brought about by this drug can also cause one to develop gynecomastia rather quickly. Should one notice an uncomfortable soreness, swelling or lump under the nipple, an ancillary drug like Nolvadex should be added immediately. This will minimize the effect of estrogen greatly, making the steroid much more tolerable to use. The powerful anti-aromatases Arimidex, Femara, or Aromasin are yet a better choice. Those who have a known sensitivity to estrogen may find it more beneficial to use ancillary drugs like Nolvadex and Proviron from the onset of the cycle, in order to prevent estrogen related side effects before they become apparent.

 

Nandrolone Cypionate Applications:

 

Nandrolone-Cypionate is one of the numerous Nandrolone compounds on the market,however, it's not as common as the immensely popular and highly available Nandrolone-Decanoate (Deca-Duraboli)). Deca-Durabolin is carried by every supplier on earth and any pharmacy the world over,and after that we have Nandrolone-Phenylpropionate (Durabolin or NPP),and then we have

 

It can help to rebuild body tissue, increase body and bone mass and encourage the formation of red blood cells. Nandrolone cypionate is an anabolic steroid which is a group of drugs that are usually synthesized from the male reproduction hormone testosterone. 

 

intermediate. It self as an anabolic hormone drugs, can promote protein synthesis and inhibiting protein dysplasia, and can lower blood cholesterol, reduce calcium phosphorus excretion and reduce bone marrow suppression, promoting development, promote tissue freshmen and granulation. Caused by long-term use of adrenal cortical hormone have prevention and protection against the adrenal cortex hypofunction.

Second only to Dianabol (methandrostenolone) as a bodybuilding anabolic steroid. Additionally, it has had considerable medical importance particularly for treatment of anemia, and more recently to help maintain lean body mass in HIV-compromised patients.

Alienation can promote protein synthesis and inhibiting protein, and can lower blood cholesterol, reduce calcium phosphorus excretion and reduce bone marrow suppression, promote development and so on.