Hormone drugs used in treating deficient hormone levels in body, thyroid problems, ovulation

chemical-categories

Anabolic Steroid Hormones Drostanolone Enanthate For Cutting Cycles 472-61-145

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Breast Cancer Treatment Female Sex Hormone Steroid Powder Progesterone 57-83-0

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Breast Cancer Treatment Female Sex Hormone Steroid Powder Progesterone 57-83-0
 
Progesterone Basic Info.:
 
Product Name: Progesterone 
Synonyms: Progestin;PRIMOLUT
CAS: 57-83-0 
MF: C21H30O2 
MW: 314.46 
EINECS: 200-350-6 
mp:  128-132°C(lit.)
alpha:  186°(c=1, ethanol) 
refractive index:  182 ° (C=2, Dioxane) 
storage temp:  Store at RT 
solubility  H2O:  25 mg/mL, may be clear to slightly hazy
Appearance:  white powder
Water Solubility:  <0.1 g/100 mL at 19°C  
Stability:  Stable. Incompatible with strong oxidizing agents. 
 
Progesterone Description:
 
Progesterone is a female Progesterone Hormones important for the regulation of ovulation and menstruation. 
 
Women take progesterone by mouth for inducing menstrual periods who have not yet reached menopause but are not having periods due to a lack of progesterone in the body; And treating abnormal uterine bleeding associated with hormonal imbalance, and severe symptoms of premenstrual syndrome (PMS). Progesterone is also used to prevent overgrowth in the lining of the uterus in postmenopausal women who are receiving estrogen hormone replacement therapy. Progesterone is also used in combination with the hormone estrogen to "oppose estrogen" as part of hormone replacement therapy. If estrogen is given without progesterone, estrogen increases the risk of uterine cancer.
 
One of progesterone's most important functions is to cause the endometrium to secrete special proteins during the second half of the menstrual cycle, preparing it to receive and nourish an implanted fertilized egg. If implantation does not occur, estrogen and progesterone levels drop, the endometrium breaks down and menstruation occurs.
 
If a pregnancy occurs, progesterone is produced in the placenta, and levels remain elevated throughout the pregnancy. The combination of high estrogen and progesterone levels suppress further ovulation during pregnancy. Progesterone also encourages the growth of milk-producing glands in the breast during pregnancy.
 
High progesterone levels are believed to be partly responsible for symptoms of premenstrual syndrome (PMS), such as breast tenderness, feeling bloated and mood swings. When you skip a period, it could be because of failure to ovulate and subsequent low progesterone levels.  
 
Progesterone Applications:
 
Progesterone is a female Progesterone Hormones important for the regulation of ovulation and menstruation. 
Women take progesterone by mouth for inducing menstrual periods who have not yet reached menopause but are not having periods due to a lack of progesterone in the body; And treating abnormal uterine bleeding associated with hormonal imbalance, and severe symptoms of premenstrual syndrome (PMS). Progesterone is also used to prevent overgrowth in the lining of the uterus in postmenopausal women who are receiving estrogen hormone replacement therapy. Progesterone is also used in combination with the hormone estrogen to "oppose estrogen" as part of hormone replacement therapy. If estrogen is given without progesterone, estrogen increases the risk of uterine cancer.
 

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Factory Direct Supplying Anabolic Steroids Hormone Powder 7-Keto DHEA 566-19-8

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Factory Direct Supplying Anabolic Steroids Hormone Powder 7-Keto DHEA 566-19-8
 
7-Keto-DHEA Basic Info.:
 
Product name: 7-keto DHEA
Synonym: 7-KETO; 5-androstene-3b-ol-7, 17-dione; 5-ANDROSTEN-3-BETA-OL-7, 17-DIONE; 7-KETO-DEHYDROEPIANDROSTERONE; 7-KETO DHEA; 7-hydroxydehydroepiandrosterone; 7-Oxo-dehydroepiandrosterone; Androst-5-ene-7, 17-dione, 3beta-hydroxy
CAS Number: 566-19-8
Assay: 98.5%min
Molecular Formula: C19H26O3
Molecular Weight: 302.41
Appearance: White crystalline powder
 
7-Keto-DHEA Description:
 
7-keto-DHEA is a by-product of dehydroepiandrosterone (DHEA), a chemical that is formed in the body. DHEA is a "parent hormone" produced by glands near the kidneys. But unlike DHEA, 7-keto-DHEA is not converted to steroid hormones such as androgen and estrogen. Taking 7-keto-DHEA by mouth or applying it to the skin does not increase the level of steroid hormones in the blood.People take 7-keto-DHEA to speed up the metabolism and heat production to promote weight loss. 7-keto-DHEA is also used to improve lean body mass and build muscle, increase the activity of the thyroid gland, boost the immune system, enhance memory, and slow aging.
 
7-Keto-DHEA Applications:
 
7-oxodehydroepiandrosterone (7-oxo DHEA and more commonly known as the brand name 7-keto) is one of three oxygenated metabolites of Dehydroepiandrosterone, and these three oxygenated metabolites interconvert with one another but do not convert back into parent DHEA; 7-keto supplementation is a way to get these three oxygenated metabolites without using DHEA supplementation, and DHEA may form androgenic and estrogenic hormones via an alternate metabolic pathway (which 7-keto does not participate in).
 
7-keto supplementation is mostly known to not be hormonal; it can interact with steroid metabolism but the exact manner in which it does it not fully elucidated. It does appear to have anti-cortisol mechanisms as the enzymes that activate cortisol (from the relatively inactive precursors of cortisone and corticosterone) are the same that interconvert these oxygenated metabolites. Although it appears to be anti-cortisol by its mechanisms, there is insufficient evidence to support these mechanisms in the body following oral supplementation.
 
Studies using 7-keto supplementation tend to note an increased metabolic rate later on during a caloric restriction period (which is secondary to reducing the rate of metabolic rate decline associated with dieting, and becoming a relative increase) although the quantity of data on this is pretty minimal if we exclude studies with possible conflicts of interest or those that use 7-keto alongside a multitude of supplements.7-keto appears to be a somewhat promising non-hormonal fat burning agent but requires more evidence on both of those claim.
 

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High Purity Male Hormone Raw Anabolic Trenbolone Steroids Mibolerone 3704-09-4

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High Purity Male Hormone Raw Anabolic Trenbolone Steroids Mibolerone 3704-09-4
 
Mibolerone Basic Info.:
 
Product Name: Mibolerone
CAS: 3704-09-4
MF: C20H30O2
MW: 302.45
EINECS: 223-046-5
Chemical Properties: White Crystalline Solid
Usage: Synthetic anabolic steroid related to testosterone. Controlled substance (anabolic steroid)
 
Mibolerone Description:
 
Mibolerone was initially as a veterinary product used to keep female dogs under control while they are in heat by shutting down the cycling of their ovaries. With proper timing, breeders are able to regulate the heat cycles of their bitches. Eventually, athletes began to utilize the product in order to boost aggression before events. It was even rumored that Mike Tyson was on Cheque Drops during the infamous ear biting incident during his bout with Holyfield. 
 
However, the late great guru Dan Duchaine discovered the application of Cheque Drops in modern bodybuilding far before that. The drops went in and out of production several times, before making a recent insurgence due to the piqued interest in the product thanks to the growing popularity of ultimate fighting circles.
 
Mibolerone Applications:
 
It is most commonly used by athletes about 30-40 minutes before their sporting event. Cheque drops are placed under the athletes tongue, and effects including aggression, strength and adrenaline rush are felt rapidly.  The drug leaves the body with in approximately four hours.
 
As well as being one of the most androgenic compounds, mibolerone is also one of the most toxic.   The most common side effect is progesterone related gynecomastia because it is a 19 nor-androgen.  
 

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Pharmaceutical Raw Materials Desonide Used To Treat Atopic Dermatitis 638-94-8

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Pharmaceutical Raw Materials Desonide Used To Treat Atopic Dermatitis 638-94-8
 
Desonide Basic info:
 
Product Name: Desonide
Synonyms: Prednacinolone;Desonide;D-2083;Steroderm
CAS NO.: 638-94-8
Molecular Formula: C24H32O6
Molecular Weight: 416.51
EINECS: 211-351-6
Assay: 99.5%
Melting point: 272-274°C
Storage temp.: Refrigerator
Appearance: White powder
Product Categories: Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;Steroids;SPORANOX;Hormone Drugs.
Usage: 
(1)With acetal-based adrenal cortex hormones;
(2)Antifungal;
(3)Anti-inflammatory. Desonide has also been found as an impurity in budesonide (B689490).
How to use desonide topical: Use this medication only on the skin.
 
Desonide Description:
 
Desonide Ointment, 0.05% contains Desonide (Pregna - 1,4 - diene - 3,20 - dione,11,21 - dihydroxy - 16,17 - [(1 - methylethylidene)bis(oxy)] - ,(11β,16α)) a synthetic corticosteroid for topical dermatologic use. The corticosteroids constitute a class of primary synthetic steroids used topically as anti-inflammatory and antipruritic agents.
 
Chemically, Desonide, the active ingredient in Desonide Ointment, 0.05% is C24H32O6. It has the following structural formula:
 
The molecular weight of Desonide is 416.51. It is a white to off-white powder. The solubility of Desonide in distilled water saturated with ether is 184 mg/L.
Each gram of Desonide Ointment, 0.05% contains 0.5 milligram of Desonide microdispersed in a base of white petrolatum.
 
Desonide Application:
 
Desonide belongs to the group of medications known as topical corticosteroids. It is used to Treat various skin conditions, including rashes. It works by reducing inflammation and itching.
 
Endogenous eczema clinical cure rate, the overall curative effect is distinct, and the low Incidence of adverse reactions, is a safe and effective external cortex hormone.
 
Wash your hands. Before applying the medication, clean and dry the affected area. Apply a thin film of the medication to the affected area and gently rub in, usually 2-3 times daily, or as directed by your doctor. If using the gel, apply the gel usually only 2 times daily. Do not bandage, wrap, or cover the area unless you are instructed to do so by your doctor. If used in the diaper area on an infant, do not use tight-fitting diapers or plastic pants.
 
After applying the medication, wash and dry your hands, unless you are using this medication to treat the hands. When applying this medication near the eyes, avoid getting it in the eyes because this may worsen or cause glaucoma, or cause irritation. Also, avoid getting this medication in the nose or mouth. If you get this medication in your eyes, nose, or mouth, rinse immediately with plenty of water.
 

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T3 Fat Loss Steroid 98% Liothyronine Sodium Herbal Weight Loss Powders 55-06-1

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T3 Fat Loss Steroid 98% Liothyronine Sodium Herbal Weight Loss Powders 55-06-1
Organic Herbal Weight Loss Powders For Tablet / Capsule Liothyronine Sodium 
 
Liothyronine Sodium Basic Info.
 
Product Name: Liothyronine Sodium
Alias : T3 Sodium Salt; T3,Na; Liothyronine Sodium; Liothyronine Sodium Salt; Cytomel T3 
CAS NO: 55-06-1
MF: C15H11I3NNaO4
MW: 672.96
Einecs No: 200-223-5
Purity: 99%
Melting point: 205°C (dec.)(lit.)
Alpha: 20°(c=2,alcohol/1.2N HCl)
Storage temp.: 2-8°C
Solubility: 4 M NH4OH in methanol: 125 g/5mL, clear, yellow-brown
Appearance: white to beige powder, almost tasteless.
Product Categories: Amino Acids & Derivatives;Intermediates & Fine Chemicals;Pharmaceuticals;Steroid and Hormone;Isolabel;Other APIs.
Usage: 
(1)One of the hormones produced by the thyroid gland that is involved in the maintenance of metabolic homeostasis. Also produced in peripheral tissues as the active metabolite of Thyroxine.
(2)Cytochrome P450 inhibitor, Ca antagonist, anesthetic (local)Product 
 
Liothyronine Sodium Description :
 
Triiodothyronine, also known as T3, is a thyroid hormone. It affects almost every physiological process in the body, including growth and development, metabolism, body temperature, and heart rate.
 
Production of T3 and its prohormone thyroxine (T4) is activated by thyroid-stimulating hormone (TSH), which is released from the pituitary gland. This pathway is regulated via a closed-loop feedback process: Elevated concentrations of T3, and T4 in the blood plasma inhibit the production of TSH in the pituitary gland. As concentrations of these hormones decrease, the pituitary gland increases production of TSH, and by these processes, a feedback control system is set up to regulate the amount of thyroid hormones that are in the bloodstream.
 
As the true hormone, the effects of T3 on target tissues are roughly four times more potent than those of T4.Of the thyroid hormone that is produced, just about 20% is T3, whereas 80% is produced as T4. Roughly 85% of the circulating T3 is later formed in the thyroid by removal of the iodine atom from the carbon atom number five of the outer ring of T4. In any case, the concentration of T3 in the human blood plasma is about one-fortieth that of T4. This is observed in fact because of the short half-life of T3, which is only 2.5 days.This compares with the half-life of T4, which is about 6.5 days.
 
Liothyronine Sodium Application:
 
High Purity Liothyronine sodium/Cytomel T3/3,3',5´╝Źtriiodothyronine sodium/CAS No: 55-06-1 200-223-5 Weight Loss Powders
Liothyronine is the most potent form of thyroid hormone. Chemically, it is nearly identical to triiodothyronine (T3). As such, it acts on the body to increase the basal metabolic rate, affect protein synthesis and increase the body's sensitivity to catecholamines (such as adrenaline) by permissiveness. The thyroid hormones are essential to proper development and differentiation of all cells of the human body. These hormones also regulate protein, fat, and carbohydrate metabolism, affecting how human cells use energetic compounds.
In comparison to levothyroxine (T4), liothyronine has a faster onset of action as well as a shorter biological half-life, which may be due to less plasma protein binding to thyroxine-binding globulin and transthyretin.
 
Physicians can use this instead of or in addition to levothyroxine (T4) for patients undergoing thyroid withdrawal. When a patient has thyroid cancer or Graves' disease, ablation therapy with radioactive iodine can be used to remove any trace thyroid tissue. For 131I therapy to be effective, the trace thyroid tissue must be avid to iodine. The best method is to starve the tissue of iodine but this can lead to hypothyroid symptoms for the patient. Withdrawal from levothyroxine can be done but it takes six weeks of withdrawal for the remaining thyroid tissue to be completely starved. Six weeks is needed owing to levothyroxine's long half life. Six weeks can be inconvenient for the patient and delay treatment. Liothyronine instead can be taken and withdrawn from for two weeks to starve the thyroid tissue. This is much safer and more convenient than levothyroxine.
 

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6-Oxo Muscle Building Steroids 4-Androstene-3 to Increase Muscle Mass 2243-06-3

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6-Oxo Muscle Building Steroids 4-Androstene-3 to Increase Muscle Mass 2243-06-3
 
6-OXO Basic Info.
 
Product Name: 6-OXO
Alias: 4-androstene-3, 6, 17- trione; Androst-4-ene-3, 6, 17-trione; 4-Androstenetrione; 4-Androstenetriol
CAS: 2243-06-3
Molecular Weight: 300.39
Molecular Formula: C19H24O3
Melting Point: 223-224° C
Package: Foil bag or tin, or as you require
Properties: White powder
Usage: Steroid drug intermediates. Low Estrogen Levels. 
Payment: T/T, Western Union and Money Gram
Delivery: Within 12hours After Your Payment
Express: EMS, DHL, FedEx, etc(door-to-door) 
 
6-OXO Description:
 
6 OXO refer to the same chemical compound that is a steroidal testosterone booster/anti-aromatase agent. First identified in cow adrenal glands it was further found to be a natural metabolite of androstenedione metabolism in humans and most mammals. This makes 6 OXO a perfectly legal dietary supplement under the current DSHEA law and since it is not androgenic, not at all an anabolic steroid. What 6 OXO does is reduce an enzyme in the body that turns your testosterone into estrogen. By blocking this enzyme two major things happen, first it causes you to keep more of your testosterone and second, the body senses a lack of estrogen and causes the testes to release more testosterone.
 
6 OXO has been well studied in men and the original manufacturer of 6 OXO, Ergopharm Inc actually paid for quite a few studies in both men and rats. The most telling one was done by Incledon, which studied 6 OXO in doses of 300mg in healthy men, then measured the effects. The Incledon study found a boost of testosterone of about 200% with a slight reduction in estradiol, which means it was very effective at boosting testosterone while reducing estrogen. This was the first really well tested testosterone booster on the market.
 
Applications Of 6-OXO:
 
Study delivered a dose of 50 mg of 1-DHEA for 10 months with no serious adverse events reported.
1-DHEA was administered at a dose of 200 mg/day for 24 weeks with slight androgenic effects noted.
 

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High Quality Local Anesthetic Prilocaine Hydrochloride Prilocaine HCl 1786-81-8

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High Quality Local Anesthetic Prilocaine Hydrochloride Prilocaine HCl 1786-81-8
 
Prilocaine HCL Basic Info.:
 
Product Name: Prilocaine HCL
CAS: 1786-81-8
English name: Propitocaine hydrochloride
Other name: Prilocaine hydrochloride; 2 - propylamine base - o C amide toluene hydrochloride; Prilocaine hydrochloride; Prilocaine hydrochloride
Molecular formula: C13H21ClN2O
EINECS: 217-244-0
Molecular Weight: 256.7716
 
Prilocaine HCL Description:
 
Propitocaine hydrochloride is a local anesthetic of the amino amide type first prepared by Claes Tegner and Nils Lö Fgren. In its injectable form, it is often used in dentistry. It is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/prilocaine or EMLA), for treatment of conditions like paresthesia. As it has low cardiac toxicity, it is commonly used forintravenous regional anaesthesia.
 
In some patients, a metabolite of prilocaine may cause the unusual side effect of methemoglobinemia, which may be treated with methylene blue.
 
Local anesthetic is a substance that causes loss of sensation only to the area to which it is applied without affecting consciousness. Most local anesthetics structures have amino-ester or an amino-amide group which are linked to hydrophilic (secondary or tertiary amine) and to hydrophobic group (aromatics) on the other side.
 
Local anesthetics, long duration, lower toxicity, chemicals that are also small Suitable for epidural anesthesia, block anesthesia and infiltration anesthesia, etc.
 

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Women Prohormones Steroids Progestone Progesterone Hormon Altrenogest 850-52-2

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Women Prohormones Steroids Progestone Progesterone Hormon Altrenogest 850-52-2 
 
Altrenogest Basic Info.
 
Product Name: Altrenogest 
CAS No.: 850-52-2  
Formula: C21H26O2  
Molecular Weight: 310.47  
EINECS: 212-703-1  
Density: 1.15 g/cm3  
Boiling Point: 495.6 °C at 760 mmHg  
Flash Point: 210.1 °C    
Storage: store in cool, dry, ventilated place.
PackAge: Foil Bag or According to Your Requirements.
 
Altrenogest Application:
 
Altrenogest is indicated (labeled) to suppress estrus in mares to allow a more predictable occurrence of estrus following withdrawal of the drug. It is used clinically to assist mares to establish normal cycles during the transitional period from anestrus to the normal breeding season often in conjunction with an artificial photoperiod. It is more effective in assisting in pregnancy attainment later in the transition period. One group of authors (Squires et al. 1983) suggest selecting mares with considerable follicular activity (mares with one or more follicles 20 mm or greater in size) for treatment during the transitional phase. Mares that have been in estrus for 10 days or more and have active ovaries are also considered to be excellent candidates for progestin treatment.
 
Altrenogest is effective in normally cycling mares for minimizing the necessity for estrus detection, for the synchronization of estrus and permitting scheduled breeding. Estrus will ensue 2-5 days after treatment is completed and most mares ovulate between 8-15 days after withdrawal. Altrenogest is also effective in suppressing estrus expression in show mares or mares to be raced. Although the drug is labeled as contraindicated during pregnancy, it has been demonstrated to maintain pregnancy in oophorectomized mares and may be of benefit in mares who abort due to sub-therapeutic progestin levels.
 
Altrenogest Adverse Effects/Warnings:
 
Adverse effects of altrenogest appear to be minimal when used at labeled dosages. One study (Shideler et al. 1983) found negligible changes in hematologic and most "standard" laboratory tests after administering altrenogest to 4 groups of horses (3 dosages, 1 control) over 86 days. Occasionally, slight changes in Ca++, K+, alkaline phosphatase and AST were noted in the treatment group, but values were only slightly elevated and only noted sporadically. No pattern or definite changes could be attributed to altrenogest. No outward adverse effects were noted in the treatment group during the trial.
 
The following people should not handle the product:
1).Women who are or suspect that they are pregnant
2).Anyone with thrombophlebitis or thromboembolic disorders or with a history of these events
3).Anyone having cerebrovascular or coronary artery disease
4).Women with known or suspected carcinoma of the breast
5).People with known or suspected estrogen-dependent neoplasia
6).Women with undiagnosed vaginal bleeding
7).People with benign or malignant tumor which developed during the use of oral contraceptives or other estrogen containing products.
 

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98% Injectable Polypeptide Hormones Eptifibatide Raw Steroid Powders 148031-34-9

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98% Injectable Polypeptide Hormones Eptifibatide Raw Steroid Powders 148031-34-9
 
Eptifibatide Basic Info.
 
Product Name: Eptifibatide
Synonyms: Human Eptifibatide; Eptifitide
Sequence: Mpr-Har-Gly-Asp-Trp-Pro-Cys-NH2
Cas No.: 148031-34-9
Molecular Formula: C35H49N11O9S2
Molecular Weight: 831.96
Appearance: White slightly yellwish powder.
Specific Rotation[20/D]: -75.0~-95.0°(C=1,1%HAc)
Amino Acids composition: ± 10%
Peptide Purity (By HPLC): >98% by area integration.
Related Substance (By HPLC): Total Impurities (%)<2.0%;Largest Single Impurity (%)< 1.0%
Water Content (Karl Fischer): <8.0%
Peptide Content(N determination): >80%
Acetate Content: <15%
IR spectrum: in accordance
Grade : Pharmaceutical Grade
Storage: Closed, below 2 ~ 8ºC preservation
Usage : Platelet glycoprotein receptor antagonist model, the third generation of antiplatelet drugs. For acute coronary syndrome (including unstable angina or non Q wave myocardial infarction) or percutaneous coronary interventional therapy (including angioplasty or atheromatous plaque excision).
 
Description Of Eptifibatide:
 
Eptifibatide (Integrilin, Millennium Pharmaceuticals, also co-promoted by Schering-Plough/Essex), is an antiplatelet drug of the glycoprotein IIb/IIIa inhibitor class.[1] Eptifibatide is a cyclic heptapeptide derived from a protein found in the venom of the southeastern pygmy rattlesnake (Sistrurus miliarius barbouri). It belongs to the class of the so-called arginin-glycin-aspartat-mimetics and reversibly binds to platelets. Eptifibatide has a short half-life. The drug is the third inhibitor of GPIIb/IIIa that has found broad acceptance after the specific antibody abciximab and the non-peptide tirofiban entered the global market.
Integrilin is sold in two strengths, globally: vials containing 2 mg/ml (20 mg totally) and 0.75 mg/ml (75 mg totally).
 
Application Of Eptifibatide:
 
Eptifibatide is used to reduce the risk of acute cardiac ischemic events (death and/or myocardial infarction) in patients with unstable angina or non-ST-segment-elevation (e.g., non-Q-wave) myocardial infarction (i.e., non-ST-segment elevation acute coronary syndromes) both in patients who are to receive non surgery (conservative) medical treatment and those undergoing percutaneous coronary intervention (PCI).
 
The drug is usually applied together with aspirin or clopidogrel and (low molecular weight or unfractionated) heparin. Additionally, the usual supportive treatment consisting of applications of nitrates, beta-blockers, opioid analgesics and/or benzodiazepines should be employed as indicated. Angiographic evaluation and other intensive diagnostic procedures may be considered a first line task before initiating therapy with eptifibatide.
 

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