Hormone drugs used in treating deficient hormone levels in body, thyroid problems, ovulation

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Body Slimming Fitness Lose Weight L-Carnitine Injection For Weight Loss 541-15-1

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Body Slimming Fitness Lose Weight L-Carnitine Injection For Weight Loss 541-15-1
 
L-Carnitine Basic Info:
 
Product Name: L-Carnitine
Synonyms: Left Carnitine; L-Carnitine; Levocarnitine; L-Carnithine; L-Carnitin;L-Carnitine;
CAS: 541-15-1
MF: C7H15NO3
MW: 161.2
EINECS: 208-768-0
Assay: Above 99.6%
Melting point: 197-212 °C(lit.)
Alpha: -31 º (c=10, H2O)
Refractive index: -32 ° (C=1, H2O)
Storage temp.: 2-8°C
Solubility: H2O: 0.1 g/mL at 20 °C, clear, colorless.
Water Solubility: 2500 g/L (20 ºC)
Appearance: White crystalline powder
Category: Medicine grade Weight loss raw material.
Usage: L-Carnitine is a natural, vitamin-like nutrient wich plays an important role inhuman metabolism. It is essential in the utilization of fatty acids and in transporting metabolic energy.
Limited Use: GB 2760-1996: chewable tablet, drink liquid, capsule, 250~600mg/tablets, sticks, balls; milk powder, 300~400g/kg; juice (flavored) drinks, milk drinks, 600~3000mg/kg.
 
L-Carnitine Attribute:
 
L-Carnitine forms white crystal or a white crystalline powder. L-carnitine has a slight characteristic odor. L-carnitine is extremely hygroscopic and even deliquescent and it can liquefy on exposure to air.L-carnitine is highly soluble in water, in alcohol, in alkaline solutions and in dilute mineral acids. L-carnitine is practically insoluble in acetone or ethyl acetate.
 
L-Carnitine Effect:
 
L-carnitine is supplement our new approved the use of animal nutrition. Mainly used for reinforcement additive protein based, can promote the absorption and utilization of fat. D type and DL type no nutritional value. The use of 70-90mg/kg. 68gL- carnitine). For the appetizer, pharmaceutical, nutritional health products, functional beverages, feed additives.
 
Mainly used in the soy based infant food, It can be added to milk powder to improve the nutrition. promote fat absorption and utilization. Our country law can be used for biscuits, drinking liquor and beverage, use the weight of 600~3000mg/kg; On the solid beverage, oral liquid and capsule with 250 ~ 600mg/kg in milk powder; Used in the volume of 300 to 400mg/kg; In infant formula food use amount is 70 ~ 90mg/kg (L-carnitine meter, 1g tartaric acid salt is equivalent to 0.68g L-carnitine).
 
L-carnitine can burn the redundant adipose in our body, then transmit to energy, which can help us lose weight. it is good for improve the explosive force and resist fatigue,which can enhance our sports ability. nutritional supplement for human body, with the growth of our age, the content of L-carnitine in our body is decreasing,so we should supplement L-carnitine to maintain the health of our body.
 

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Masteron Raw Steroid Powder Drostanolone Propionate For Muscle Building 521-12-0

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Masteron Raw Steroid Powder Drostanolone Propionate For Muscle Building 521-12-0
 
Drostanolone Propionate Basic Info.
 
Product Name: Drostanolone Propionate 
Synonyms: Masteron; Dromostanolone Propionate 
CAS: 521-12-0 
Molecular formula: C23H36O3 
Molecular weight: 360.53 
EINECS: 208-303-1 
Assay: 99%
Packing: Foil bag or tin. 
Delivery: Express courier. 
Character: White crystalline powder. 
Min. order quantity: 100g
Payment: T/T, Western Union, Moneygram
Express: EMS, DHL, FeDex, etc(door-to-door)
Delivery : safe & timely, within 12 hours after payment
 
Drostanolone Propionate Description:
 
Masteron can be used somewhat effectively as bulking agent, providing a consistent gain of high quality muscle mass. It can also be successfully combined with other steroids for an enhanced effect. Mixing drostanolone with an injectable anabolic such as Deca-Durabolin or Equipoise can prove quite useful for example, the two providing notably enhanced muscle gain without excessive water retention. For greater mass gains, a stronger androgen such as Dianabol or an injectable testosterone would do the trick. The result here can be an extreme muscle gain, with a lower level of water retention & other estrogenic side effects than if these steroids were used alone (usually in higher doses). Masteron could of course be used during cutting phases of training as well. A cycle of this drug combined with Winstrol, Primobolan or Oxandrolone should provide great muscle retention and fat loss, during a period which can be very catabolic without steroids. It is an added benefit that none of these steroids aromatize, and therefore there is no additional worry of unwanted water and fat retention.
 
Drostanolone Propionate Applications:
 
Bodybuilders have a strong like for non-aromatizing androgens, and find Masteron very useful in a cutting phase. It is generally used for a number of weeks prior to a competition, in an effort to bring out an improved look of density and hardness to the muscles. As long as body fat percentage is low enough, considerably intensifies its anabolic effect. It can therefore be used somewhat effectively as bulking agent, providing a consistent gain of high quality muscle mass.
 
Masteron is often an ideal choice for inclusion in a steroid stack, or in some cases for use as the sole injectable for a steroid cycle.Androgens and assimilation hormonal.
 
An enanthate ester version having a half-life of probably 5 days has become available. This version of Masteron may be injected as infrequently as twice per week.
 

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Oral Anabolic Steroid Hormone Dianabol Methandienone Gain in Muscle Size 72-63-9

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Oral Anabolic Steroid Hormone Dianabol Methandienone Gain in Muscle Size 72-63-9
 
Methandienone Basic Info.:
 
Product Name: Metandienone
Alias: Dianabole, Dianabole,  Encephan, Geabol, Metanabol, Metandienon, Metandienonum, Metandrostenolon, Metandrostenolone, Metastenol, Methandrolone, Naposim, Nerobol, Nerobolettes, NSC-42722, Protobolin, Stenolon, Stenolone, Sterolon.
CAS: 72-63-9
MF: C20H28O2
MW: 300.43512
EINECS: 200-787-2
Purity: 99%
Melting point: 165-166 °C
Storage temp.: 2-8°C
Appearance: White powder.
Product Categories: Biochemistry;Hydroxyketosteroids;Steroids;Intermediates & Fine Chemicals;Pharmaceuticals;Steroid and Hormone;Finished Steroid and Hormone;API
Usage: 
(1)It can be should as medicines of androgens and anabolic hormones. 
(2)It can be used for treating expendable chronic disease, children mal-development, osteoporosis and hyperlipidemia.
(3)Anabolic steroid. Androgen. Controlled substance. 
 
Methandienone Description:
 
One of the most important anabolic steroids in bodybuilding ever since its introduction in 1958. Also commonly known as "Dbol", this oral compound is best used for steroid cycles in combination with injectable steroids, but can be of value used alone as well. Methandrostenolone is a derivative , and exhibits a strong anabolic effect along with a moderate androgenic effect. Methandrostenolone is also commonly known as 'dianabol' which is the old Ciba brand name. Methandrostenolone is an oral steroid, which is potent. 
 
Methandienone Applications:
 
One of the most important anabolic steroids in bodybuilding ever since its introduction in 1958. Also commonly known as "Dbol", this oral compound is best used for steroid cycles in combination with injectable steroids, but can be of value used alone as well.
 
(Dianabol) is the most well known Steroid in existance today and was considered by Arnold schwarzenegger to be the 'breakfast of champions'. Dianabol is a very strong compound and takes very litle time to take effect, by two weeks you will be noticing huge effects from this drug.
 
One of the great benefits of Dianabol is its ability to make one feel good inside, confident and powerful. All three are vastly important in performing well in the gym and Dianabol will certainly make you perform well in the gym! In the gym you will notice huge gains in strength and you will find that your muscle fill very full and large, this is mostly due to the fact that it dramatically increases protein synthesis and nitrogen retention within the muscle cells. - training on Dianabol is a great experience.
 
With regards to weight gains Dianabol is a champion at making the scales go up and almost nothing can do that faster than this compound. Because of this it is an ideal Steroid to take at the start of a Steroid cycle, what is known as a 'kick-start' and for this reason it is best used, and almost always used, in conjunction with injectable Steroids.
 
A typical dose would be 40-60mg/day and many serious Bodybuilders will go up to 100mg/day, however, it is important to note that Dianabol can impact your blood pressure levels at higher doses.
 

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Prohormones Steroids White Powder Misoprostol For Terminate Pregnancy 59122-46-2

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Prohormones Steroids White Powder Misoprostol For Terminate Pregnancy 59122-46-2
 
Misoprostol Basic Info.
 
Product Name: Misoprostol
Synonyms: Misoprostol;Cytotec;SC-29333
CAS: 59122-46-2
Molecular Formula: C22H38O5
Molecular Weight: 382.60
Assay: 99%
Chemical Properties: White Solid
Solubility: Soluble to 100 mM in Ethanol
Safety: Poison by ingestion, intramuscular, and intraperitoneal routes. When heated to decomposition it emits acrid smoke and irritating fumes.
Package: Aluminium foil bag packing 
Storage: Keep in cool and dry place, away from light
 
Misoprostol Description:
 
Misoprostol is a medication used to start labor, induce abortions, prevent and treat stomach ulcers, and treat postpartum bleeding due to insufficient contraction of the uterus. For abortions it is used with mifepristone or methotrexate. It is a synthetic prostaglandin E1 (PGE1).
 
Common side effects include diarrhea and abdominal pain. It is pregnancy category X meaning that it is known to result in negative fetal outcomes if taken during pregnancy. Uterine rupture may occur.
 
It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system. Misoprostol was invented and marketed by G.D. Searle & Company under the trade name Cytotec, but other trade names and generic formulations are available.
 
Misoprostol Usage
 
Misoprostol is approved for use in the prevention of NSAID-induced gastric ulcers. It acts upon gastric parietal cells, inhibiting the secretion of gastric acid by G-protein coupled receptor-mediated inhibition of adenylate cyclase, which leads to decreased intracellular cyclic AMP levels and decreased proton pump activity at the apical surface of the parietal cell. Because other classes of drugs, especially H2-receptor antagonists and proton pump inhibitors, are more effective for the treatment of acute peptic ulcers, misoprostol is only indicated for use by people who are both taking NSAIDs and are at high risk for NSAID-induced ulcers, including the elderly and people with ulcer complications. Misoprostol is sometimes coprescribed with NSAIDs to prevent their common adverse effect of gastric ulceration (e.g. with diclofenac in Arthrotec).
 
Misoprostol has other protective actions, but is only clinically effective at doses high enough to reduce gastric acid secretion. For instance, at lower doses, misoprostol may stimulate increased secretion of the protective mucus that lines the gastrointestinal tract and increase mucosal blood flow, thereby increasing mucosal integrity. However, these effects are not pronounced enough to warrant prescription of misoprostol at doses lower than those needed to achieve gastric acid suppression.
However, even in the treatment of NSAID-induced ulcers, omeprazole proved to be at least as effective as misoprostol,but was significantly better tolerated, so misoprostol should not be considered a first-line treatment. Misoprostol-induced diarrhea and the need for multiple daily doses (typically four) are the main issues impairing compliance with therapy.
 
The most commonly reported adverse effect of taking a misoprostol orally for the prevention of stomach ulcers is diarrhea. In clinical trials, an average 13% of patients reported diarrhea, which was dose-related and usually developed early in the course of therapy (after 13 days) and was usually self-limiting (often resolving within 8 days), but sometimes (in 2% of patients) required discontinuation of misoprostol.
 
The next most commonly reported adverse effects of taking misoprostol orally for the prevention of gastric ulcers are: abdominal pain, nausea, flatulence, headache, dyspepsia, vomiting, and constipation, but none of these adverse effects occurred significantly more often than when taking placebos. In practice, fever is almost universal when multiple doses are given every 4 to 6 hours.
 
Misoprostol should not be taken by pregnant women to reduce the risk of NSAID-induced gastric ulcers because it increases uterine tone and contractions in pregnancy, which may cause partial or complete abortions, and because its use in pregnancy has been associated with birth defects.
 

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99% High Purity Local Anesthetic Tetracaine Hydrochloride/Tetracaine HCL 136-47-0

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99% High Purity Local Anesthetic Tetracaine Hydrochloride/Tetracaine HCL 136-47-0
 
Tetracaine HCL Basic Info.:
 
Product Name: Tetracaine hydrochloride
Synonyms: Tetracaine HCL
CAS: 136-47-0
MF: C15H25ClN2O2
MW: 300.82
EINECS: 205-248-5
mp: 149°C
storage temp: Refrigerator
Appearance: White Solid
Usage: Local anesthetic; Mainly used in mucosa anesthetic.The function is stronger than Procaine and Lidocaine.
 
Tetracaine HCL Description:
 
Tetracaine HCl is synthesized from 4-butylaminobenzoic acid. The ethyl ester is formed through an acid-catalyzed esterification reaction. Base-catalyzed transesterification is achieved by boiling the ethyl ester of 4-butylaminobenzoic acid with excess 2-dimethylaminoethanol in the presence of a small amount of sodium ethoxide.
 
Tetracaine HCL Applications:
 
Tetracaine (INN, also known as amethocaine; trade name Pontocaine. Ametop and Dicaine) is a potent local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.
 
In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.
 

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99% Muscle Bodybuilding Supplement Anabolic Steroid Methenolone Acetate 434-05-9

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99% Muscle Bodybuilding Supplement Anabolic Steroid Methenolone Acetate 434-05-9 
 
Methenolone Acetate Basic Info.
 
Product Name: Methenolone Acetate
Alias: Primobolan-depot;Primobolandepot;Methenolone Acetate
CAS No.: 434-05-9
MF: C22H32O3
MW: 344.49
Einecs No: 207-097-0
Purity: 99%
MOQ(minimum order quantity): 10gram
Standard: Enterprise Standard
Appearance: White powder. 
Usage: It is very strong, the synthesis of the metabolism and male characteristics is very low, making it the best choice for the game. 
 
Methenolone Acetate Description:
 
Primobolan (methenolone acetate), all things being equal, is an excellent oral steroid drug. Unlike most other oral steroids, Primobolan is not 17-alkylated and does not have liver toxicity problems. Methenolone is perhaps only half as potent by the oral route as by injection, so dosages need to be high, at least 100 and preferably 200-300 mg per day, but if that can be afforded it is an excellent drug. It is unusual among oral steroids as being Class I, binding well to the androgen receptor. 
 
Methenolone Acetate Applications: 
 
Primobolan (methenolone acetate), all things being equal, is an excellent oral steroid drug. Unlike most other oral steroids, Primobolan is not 17-alkylated and does not have liver toxicity problems. 
Primobolan is toxic to the liver, especially the oral versions, although the toxicity is gradual and slight. Acne and hair loss can occur with long-term use. 
Primobolan is a good base compound in a stack and can produce results just slightly below that of nandrolone and is best used in a cutting stack. Because Primobolan doesn't aromatize, there is no use for Clomid or Nolvadex.
Primobolan Acetate is very strong, the synthesis of the metabolism and male characteristics is very low, making it the best choice for the game. The drug for women is very good!
 

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99% Purity High Quality Steroid Hormone Powder Methandriol Dipropionate 3593-85-9

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99% Purity High Quality Steroid Hormone Powder Methandriol Dipropionate 3593-85-9
 
Methandriol Dipropionate Details:
 
Product Name: Methandriol Dipropionate
Synonyms: 5-Androsten-17Alpha-Methyl-3Beta;17Alpha-Methylandrostendiol Dipropionate;Methandriol Dipropionate;
CAS: 3593-85-9
MF: C26H40O4
MW: 416.6
EINECS: 222-735-8
Standard: Enterprise Standard
Packing: 1kg/Aluminum foil bag
Min. Order Quantity: 10g
Payment: Western Union, Moneygram
Shipment: EMS, DHL, FedEx, etc.
Delivery: Safe & Timely, Around 1 Day After Payment.
Product Categories: Steroids
 
Methandriol Dipropionate Descriptions:
 
Methandriol Dipropionate (M.D.) is a form of the water-dissolved Methandriol but Methandriol Dipropionate remains effective for a longer period of time. On the one hand, Methandriol Dipropionate can be dissolved in oil for injection purposes and, on the other hand, Methandriol Dipropionate is produced in tablet form since it is also effective when taken orally M.D. has a strong anabolic and androgenic component so that it is suitable for the buildup of strength and muscle mass. The effect can be compared to a cross between Deca-Durabolin and Testosterone enanthate. Like testosterone it con- tributes to a gain in both strength and muscle but does not retain more water than Deca-Durabolin.
 
The best results can be obtained, however, if Methandriol Dipropionate is not taken alone but in combination with an- other steroid. This is because Methandriol Dipropionate is able to magnify the effects of other steroid compounds. It does this by increasingly sensitizing the androgenic receptors of the muscle cell, allowing a higher amount of the steroid molecules of the additionally taken steroids to be absorbed by the receptors. This also explains why injectable Methandriol Dipropionate is only available today as a combination compound with an additional steroid substance. Injectable Methandriol Dipropionate is only available in the Australian veterinary steroids Drive, Spectriol, Geldabol, and Filibol Forte so that procurement of the compound is difficult. The few athletes using this drug report good strength gains, a solid muscle gain, and low water retention. The combination steroids aromatize only slightly so, when taking only Methandriol Dipropionate, the use of antiestrogens is perhaps appropriate. The injectable form is only slightly toxic.
 
Methandriol Dipropionate Dosage:
 
The usual dosage for athletes is 100 mg every 2-3 days. In Europe only the oral form of M.D. is available. Also in this case it is beneficial to combine M.D. with another steroid, preferably an injectable one. The normal daily dose is 40-60 mg and is usually taken in 2-3 individual doses spread over & day The tablets are usually taken for only 4-6 weeks since the effect decreases quickly, thus requiring higher dosages.
 

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High Quality Factory Direct Supply Estrogen Hormone Estradiol Enanthate 4956-37-0

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High Quality Factory Direct Supply Estrogen Hormone Estradiol Enanthate 4956-37-0
 
Estradiol Enanthate Basic Info.
 
Product Name: Estradiol Enanthate
CAS Number: 4956-37-0
Purity: 99%
Molecular Weight: 384.556
Molecular Formula: C25H36O3
Appearance: Crystalline powder
Physical State: Solid
Solubility: Soluble in water (slightly).
Storage: Store at room temperature
Melting Point: 94-96 ° C
Boiling Point: ~509.5 ° C at 760 mmHg (Predicted)
Density: ~1.1 g/cm3 (Predicted)
 
Estradiol Enanthate Description:
 
Estradiol enanthate (INN, USAN), or estradiol enantate, is a synthetic ester, specifically the 17-heptanoyl ester, of the natural estrogen, estradiol. It is marketed under the brand names Anafertin, Deladroxate, Perlutan, and Topasel, which are combination formulations of estradiol enanthate and dihydroxyprogesterone acetophenide, as a once-monthly injectable hormonal contraceptive in Spain and Latin America, and has been used as such since at least the mid-1960s.
 
Estradiol, or more precisely, 17β-estradiol, is a human sex hormone and steroid, and the primary female sex hormone. It is named for and is important in the regulation of the estrous and menstrual female reproductive cycles. Estradiol is essential for the development and maintenance of female reproductive tissues but it also has important effects in many other tissues including bone. While estrogen levels in men are lower compared to women, estrogens have essential functions in men as well. Estradiol is found in most vertebrates as well as many crustaceans, insects, fish, and other animal species.
 
Estradiol or oestradiol (American or British English usages), derives from estra-, Gk. οστρο? (oistros, literally meaning "verve or inspiration") and -diol, a chemical name and suffix indicating that this form of steroid and sex hormone is a type of alcohol bearing two hydroxyl groups.
 
Estradiol is produced especially within the follicles of female ovaries, but also in other endocrine (i.e., hormone-producing) and non-endocrine tissues (e.g., including fat, liver, adrenal, breast, and neural tissues). Estradiol is biosynthesized from progesterone (arrived at in two steps from cholesterol, via intermediate pregnenolone). One principle pathway then converts progesterone to its 17-hydroxy-derivative, and then to androstenedione via sequential cytochrome P450-catalyzed oxidations.Action of aromatase on this dione generates estrone, and action of a dehydrogenase on this gives the title compound, 17β-estradiol.
 
Estradiol Enanthate Function:
 
Hormones and Regulation of Endocrine Function of Drug, Nutritional Therapeutics, Antibiotic and Antimicrobial Agents, Antiparasitic, Original Drug Resistant Microbes, Immune System Drugs, Specialist Drugs, Drug Detoxification, Diagnostic Agents, Blood System Agents, Visceral System Medication, Central Nervous System Agents, Cardiovascular Agents, Urinary System Agents, Respiratory System Agents.
 
A chemical derivative of estradiol, ethinyl estradiol with maximum dosage 200 µg, is a major component of hormonal contraceptive devices. Combined forms of hormonal contraception contain ethinyl estradiol and a progestin, which both contribute to the inhibition of GnRH, LH, and FSH, which accounts for the ability of these birth control methods to prevent ovulation and thus prevent pregnancy. Other types of hormonal birth control contain only progestins and no ethinyl estradiol.
 

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Lose Stubborn Belly Fat Peptide Anabolic Peptide Cjc-1295 Without Dac 863288-34-0

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Lose Stubborn Belly Fat Peptide Anabolic Peptide Cjc-1295 Without Dac 863288-34-0
 
Basic Information For CJC-1295 Without DAC:
 
Product Name: 
Synonyms: CJC1295; CJC-1295 Acetate; CJC-1295 without DAC; CJC 1295 w/o DAC; MOD GRF 1-29; Neorelin; Modified Sermorelin
CAS: 863288-34-0
MF: C159H258N46O45
MW: 0
Density: 1.45
Molar Mass: 3368.7
Peptide purity: >98.0%
Appearance: White lyophilized powder
Related substance: Total Impurities (%) ≤ 2.0%
Acetate content: ≤ 15.0%
Bacterial Endotoxins: ≤5 IU/mg
Sequence: Tyr-d-ALA-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH2
Source: Chemical Synthesis
Reconstitution: To follow best practice guidelines for reconstituting CJC-1295 without DAC, reconstitute in sterile, bacteriostatic, distilled water, with light sonication if necessary.
Storage for MOD GRF 1-29: Lyophilized MOD GRF 1-29 is stable at room temperature for 90 days, however it should be stored in a freezer below -8°C for any extended period of time. After reconstitution, may be stored for a maximum of 14 days in a refrigerator at 2°C - 8°C. Store vials in an upright position. Store MOD GRF-129 refrigerated between temperatures 2°C - 8°C. Keep in the outer carton in order to protect from light. For one month can be stored at room temperature.
Shelf life: One year from dispatch.
 
What is CJC-1295 without DAC and used for?
 
Modified GRF 1-29 is also known as Mod GRF 1-29, but even more commonly known as CJC-1295 without DAC. It is a protein that is 29 amino acids long and it is a GHRH analogue. CJC-1295 without DAC acts on receptors at the pituitary gland to stimulate the release of Human Growth Hormone.
 
CJC-1295 without DAC could be referred to more properly as a second generation derivative of GHRH. GHRH is modified to create what is known as Releasing Factor (GRF) 1-29, also known as Sermorelin. GRF 1-29 is then further modified to create Mod GRF 1-29 which is CJC-1295 without DAC.
 
Application & More information for CJC-1295 without DAC:
 
Releasing Hormone (GHRH), which is the endogenously secreted GHRH by the arcuate nucleus of the hypothalamus of the human body, is 44 amino acids long. It was discovered, however, that only the first 29 amino acids of the protein were equally as effective in binding to receptors on the pituitary gland as the full 44 amino acid structure. The first 29 amino acids in its protein structure were then isolated, which was then called GRF 1-29, but the problem with this derivative of GHRH was the fact that it was rapidly metabolized and cleared from the body by enzymes. Studies have reported that GRF 1-29's half-life is less than 10 minutes and as little as 5 minutes. This was obviously not enough time to ensure a maximized and sustained release of HGH from the pituitary gland, as studies have demonstrated that the full potential of an HGH pulse from the pituitary requires at least 30 minutes as evidenced by the fact that much higher HGH levels (50 times greater) were observed 15 - 30 minutes into subcutaneous administration of GHRH analogues.
 
Therefore, the solution to this was to modify GRF 1-29 by replacing various amino acids in its structure with other amino acids that would provide a greater resistance to breakdown and cleavage by enzymes. There were many modified analogues developed, and Mod GRF 1-29 (CJC-1295 without DAC) was eventually selected for use, which demonstrated the most promising effects. Mod GRF 1-29 is a modification of GRF 1-29, specifically at amino acids #2, #8, #15, and #27. The result is an extended half-life to that of at least 30 minutes.
 
Mod GRF 1-29 acts upon receptors located in the anterior pituitary gland, and signals the pituitary gland to increase Human  production and cause a release of massive quantities of Human Hormone in a pulsatile manner. The effects of Mod GRF 1-29 are very similar from what would be expected from synthetic HGH administration over the long term, although the amount of time that the released human growth hormone will remain in circulation is of a far less amount of time than synthetic Human Growth Hormone does. Therefore, multiple applications of Mod GRF 1-29 is recommended throughout the day in order to simulate Human Growth Hormone levels that remain high on a constant basis. Mod GRF 1-29 (CJC-1295 without DAC) is commonly combined with a Ghrelin mimetic (also known as a GHRP - Releasing Hexapeptide), such as GHRP-6, GHRP-2, Hexarelin, or Ipamorelin in order to initiate and amplify a greater pulse from the pituitary compared to Mod GRF 1-29 used solitarily on its own.
 

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Pharmaceutical Intermediate Powder Peptide Lanreotide For Acromegaly 108736-35-2

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Pharmaceutical Intermediate Powder Peptide Lanreotide For Acromegaly 108736-35-2 
 
Lanreotide Basic Info.:
 
Product Name: Lanreotide
Synonyms: Lanreotide;Autogel;Bim-23014;Angiopeptin;Ipstyl 
CAS: 108736-35-2
MF: C54H69N11O10S2
MW: 1096.32
Storage temp.: −20°C
Chemical Properties: White to off-white lyophilised powder
Product Categories: hormones
 
Lanreotide Description:
 
Lanreotide (INN) is a medication used in the management of acromegaly and symptoms caused by neuroendocrine tumors, most notably carcinoid syndrome. It is a long-acting analogue of somatostatin, like octreotide. Its sequence is H-D-2Nal-Cys(1)-Tyr-D-Trp-Lys-Val-Cys(1)-Thr-NH2.
 
Lanreotide is used in the treatment of acromegaly, due to both pituitary and non-pituitary growth hormone-secreting tumors, and the management of symptoms caused by neuroendocrine tumors, particularly carcinoid tumors and VIPomas. In the United States and Canada, lanreotide is only indicated for the treatment of acromegaly. In the United Kingdom, it is also indicated in the treatment of thyrotrophic adenoma,a rare tumor of the pituitary gland which secretes TSH.
 
Lanreotide also shows activity against non-endocrine tumors, and, along with other somatostatin analogues, is being studied as a possible general antitumor agent.
 
Lanreotide Indications:
 
Lanreotide is used in the treatment of acromegaly, due to both pituitary and non-pituitary growth hormone-secreting tumors, and the management of symptoms caused by neuroendocrine tumors, particularly carcinoid tumors and VIPomas.  In the United States and Canada, lanreotide is only indicated for the treatment of acromegaly. In the United Kingdom, it is also indicated in the treatment of thyrotrophic adenoma, a rare tumor of the pituitary gland which secretes.
 
Lanreotide also shows activity against non-endocrine tumors, and, along with other somatostatin analogues, is being studied as a possible general antitumor agent.
 
Lanreotide ,In Dec 2014 the US FDA approved lanreotide for the treatment of patients with unresectable, well or moderately differentiated, locally advanced or metastatic gastroenteropancreatic neuroendocrine tumors (GEP-NETs).
 
Lanreotide Side Effects:
 
Lanreotide ,The main side effects of lanreotide treatment are mild to moderate pain at the injection site and gastrointestinal disturbances, such as diarrhea, nausea and vomiting. Isolated cases of gallstone formation have been associated with use of lanreotide, particularly over long periods of time.
 

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