Hormone drugs used in treating deficient hormone levels in body, thyroid problems, ovulation

chemical-categories

Pimavanserin 98%

Name

Pimavanserin

Synonyms

1-(4-Fluorobenzyl)-3-(4-isobutoxybenzyl)-1-(1-methylpiperidin-4-yl)urea

Molecular Formula

C25H34FN3O2

Molecular Weight

427.55

CAS Registry Number

706779-91-1

used in the treatment of Parkinson’s disease psychosis.

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Polypeptide Hormone Follistatin 315 Antibody Fst-315

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Polypeptide Hormone Follistatin 315 Antibody Fst-315
 
Follistatin 315 Basic Info.
 
Product Name: Follistatin 315 / Fst-315
Specification: 1mg/vial
Purity: 85%+
Appearance: White powder
Specific Optical Rotation (c=0.5,10% HAc): -50.0~-60.0°
Water Content(Karl Fischer): ≤5.0%
Acetate Content(by HPLC): ≤15.0%
Amino Acid Composition: ±10% of theoretical
Purity (by HPLC): ≥98.0%
Single Impurity(by HPLC): ≤1.0%
Peptide Content(by %N): ≥80%
Assay(By Anhydrous, Acetic Acid-free ) :95.0~105.0%
Bacterial Endotoxins: ≤5EU/mg
Storage/Stability: Stored at -20 °C if preferred. Storage in frost-free freezers is not recommended.
Note: This product is furnished for LABORATORY RESEARCH USE ONLY. Not for diagnostic or therapeutic use.
 
Description of Follistatin 315:
 
Follistatin is being studied for its role in regulation of muscle growth in mice, as an antagonist to myostatin (also known as GDF-8, a TGF superfamily member) which inhibits excessive muscle growth. Lee & McPherron demonstrated that inhibition of GDF-8, either by genetic elimination (knockout mice) or by increasing the amount of follistatin, resulted in greatly increased muscle mass.In 2009, research with macaque monkeys demonstrated that regulating follistatin via gene therapy also resulted in muscle growth and increases in strength. This research paves the way for human clinical trials, which are hoped to begin in the summer of 2010 on Inclusion body myositis.
A study has also shown that increased levels of follistatin, by leading to increased muscle mass of certain core muscular groups, can increase life expectancy in cases of spinal muscular atrophy (SMA) in animal models.
It is also being investigated for its involvement in polycystic ovary syndrome (PCOS), though there is debate as to its direct role in this infertility disease.
 
Follistatin 315 Application:
 
Follistatin 315 primary function is the binding and bioneutralization of members of the TGF-β superfamily, with a particular focus on activin, a paracrine hormone.
 
Storage Instruction
Store at +4°C or at -20°C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
 

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Polypeptide Human Growth Powder Hormone Peptide Selank CAS 129954-34-3

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Polypeptide Human Growth Powder Hormone Peptide Selank CAS 129954-34-3
 
Selank Basic Info.
 
Product Name: Selank
Alias: Selanc;Selank
Sequence: Thr-Lys-PRO-Arg-PRO-Gly-PRO
CAS: 129954-34-3
MF: C33H57N11O9
MW: 751.9
Purity: 99%
Specification: 5mg/vial
Appearance: White Lyophilized Powder
Place of Origin: China
Standard: USP
Certification: SGS
Method of Analysis: HPLC
Use: Reduce stress, relieve depression, insomnia quit. Of course, with Selank a puzzle-anxiolytic
 
Descriptions Of Selank:
 
Selank was developed by the Russian Academy of Sciences. anxiolytic peptide based drugs. Selank is a heptapeptide with the sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro. It is a synthetic analogue of a human tetrapeptide tuftsin.
 
it uses relief of anxiety and improved cognitive functioning alone. Selank used for : Stress reduction, the alleviation of depression, reversal of anhedonia, improvement in mood in emotionally stable individuals, and cessation of insomnia.
 
In fact,Selank more suitable for long-term use. for the large majority of researchers claiming that it is a "side effect free" compound. Some believe an overdose might cause fatigue.
 
Application Of Selank:
 
(1)Selank as a nootropic:
Recreationally Selank is used to improve one's ability to focus and concentrate, reduce mental fatigue, increase mental sharpness and increase memory and learning capacity. The first noticeable effect is usually stabilization of mood and general feeling of well-being.
 
(2)Selank as an antiviral agent:
Selank neuropeptide also expresses immunomodulatory effects. In 2009 a study by F. Ershov et all. has evaluated antiviral properties of Selank both in vitro and in vivo against the influenza virus strain A/Aichi 2/68 (H3N2). The pronounced antiviral effect of Selank was detected in both systems. The highest efficiency - completely supressed viral reproduction was shown when Selank was added to the cell culture 24 hours before inoculation.
 

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Prohormones Steroids White Powder Misoprostol For Terminate Pregnancy 59122-46-2

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Prohormones Steroids White Powder Misoprostol For Terminate Pregnancy 59122-46-2
 
Misoprostol Basic Info.
 
Product Name: Misoprostol
Synonyms: Misoprostol;Cytotec;SC-29333
CAS: 59122-46-2
Molecular Formula: C22H38O5
Molecular Weight: 382.60
Assay: 99%
Chemical Properties: White Solid
Solubility: Soluble to 100 mM in Ethanol
Safety: Poison by ingestion, intramuscular, and intraperitoneal routes. When heated to decomposition it emits acrid smoke and irritating fumes.
Package: Aluminium foil bag packing 
Storage: Keep in cool and dry place, away from light
 
Misoprostol Description:
 
Misoprostol is a medication used to start labor, induce abortions, prevent and treat stomach ulcers, and treat postpartum bleeding due to insufficient contraction of the uterus. For abortions it is used with mifepristone or methotrexate. It is a synthetic prostaglandin E1 (PGE1).
 
Common side effects include diarrhea and abdominal pain. It is pregnancy category X meaning that it is known to result in negative fetal outcomes if taken during pregnancy. Uterine rupture may occur.
 
It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system. Misoprostol was invented and marketed by G.D. Searle & Company under the trade name Cytotec, but other trade names and generic formulations are available.
 
Misoprostol Usage
 
Misoprostol is approved for use in the prevention of NSAID-induced gastric ulcers. It acts upon gastric parietal cells, inhibiting the secretion of gastric acid by G-protein coupled receptor-mediated inhibition of adenylate cyclase, which leads to decreased intracellular cyclic AMP levels and decreased proton pump activity at the apical surface of the parietal cell. Because other classes of drugs, especially H2-receptor antagonists and proton pump inhibitors, are more effective for the treatment of acute peptic ulcers, misoprostol is only indicated for use by people who are both taking NSAIDs and are at high risk for NSAID-induced ulcers, including the elderly and people with ulcer complications. Misoprostol is sometimes coprescribed with NSAIDs to prevent their common adverse effect of gastric ulceration (e.g. with diclofenac in Arthrotec).
 
Misoprostol has other protective actions, but is only clinically effective at doses high enough to reduce gastric acid secretion. For instance, at lower doses, misoprostol may stimulate increased secretion of the protective mucus that lines the gastrointestinal tract and increase mucosal blood flow, thereby increasing mucosal integrity. However, these effects are not pronounced enough to warrant prescription of misoprostol at doses lower than those needed to achieve gastric acid suppression.
However, even in the treatment of NSAID-induced ulcers, omeprazole proved to be at least as effective as misoprostol,but was significantly better tolerated, so misoprostol should not be considered a first-line treatment. Misoprostol-induced diarrhea and the need for multiple daily doses (typically four) are the main issues impairing compliance with therapy.
 
The most commonly reported adverse effect of taking a misoprostol orally for the prevention of stomach ulcers is diarrhea. In clinical trials, an average 13% of patients reported diarrhea, which was dose-related and usually developed early in the course of therapy (after 13 days) and was usually self-limiting (often resolving within 8 days), but sometimes (in 2% of patients) required discontinuation of misoprostol.
 
The next most commonly reported adverse effects of taking misoprostol orally for the prevention of gastric ulcers are: abdominal pain, nausea, flatulence, headache, dyspepsia, vomiting, and constipation, but none of these adverse effects occurred significantly more often than when taking placebos. In practice, fever is almost universal when multiple doses are given every 4 to 6 hours.
 
Misoprostol should not be taken by pregnant women to reduce the risk of NSAID-induced gastric ulcers because it increases uterine tone and contractions in pregnancy, which may cause partial or complete abortions, and because its use in pregnancy has been associated with birth defects.
 

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Purity 99% Medical Androsterone Androgenic Prohormone Steroids 53-41-8

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Purity 99% Medical Androsterone Androgenic Prohormone Steroids 53-41-8 
 
Androsterone Basic Info.:
 
Product Name: Androsterone
Synonyms: 3-alpha-hydroxy-17-androstanone;3alpha-Hydroxy-17-androstanone;3-alpha-hydroxy-5-alpha-androstan-17-on;3-Epihydroxyetioallocholan-17-one;3-hydroxy-,(3-alpha,5-alpha)-androstan-17-on;3-hydroxy-,(3alpha,5alpha)-androstan-17-on;5alpha-Androstan-17-one, 3alpha-hydroxy-;5alpha-Androstane-3alpha-ol-17-one
CAS: 53-41-8
MF: C19H30O2
MW: 290.44
EINECS: 200-173-4
Melting point: 181-184 °C(lit.)
Alpha: 96 º (c=1, C2H5OH)
Storage temp.: -20°C
Chemical Properties: white to light beige crystalline powder.
Usage: It was isolated from male urine after removed of the phenolic estrogen fraction. Antihypertensor.
Product Categories: Steroids;Steroids & Hormones - 13C & 2H;Intermediates & Fine Chemicals;Pharmaceuticals.
 
Androsterone Description:
 
Androsterone, or 3α-hydroxy-5α-androstan-17-one, is an endogenous steroid hormone, neurosteroid, and putative pheromone. It is a weak androgen with a potency that is approximately 1/7th that of testosterone. In addition, it can be converted to dihydrotestosterone (DHT) from 3α-hydroxysteroid dehydrogenase and 17β-hydroxysteroid dehydrogenase, bypassing conventional intermediates such as androstenedione and testosterone, and as such, can be considered to be a metabolic intermediate in its own right. 
Androsterone is also known to be an inhibitory androstane neurosteroid, acting as a positive allosteric modulator of the GABAA receptor, and possesses anticonvulsant effects. The unnatural enantiomer of androsterone is more potent as a positive allosteric modulator of GABAA receptors and as an anticonvulsant than the natural form. Androsterone's 3β-isomer is epiandrosterone, and its 5β-epimer is etiocholanolone.
 
Androsterone Applications:
 
Androsterone is one of the androgens, which are steroid hormones that affect the masculinization of the fetus and child and that maintain or create masculine traits in adults. Testosterone is the most active and abundant of the androgens. Androsterone was originally isolated from male urine in very small amounts. Many scientists believe it to be a metabolic byproduct of the breakdown of testosterone, and many scientists who study pheromones think it might be active in human relations.
 
A molecule of androsterone is very similar to testosterone. It consists of three six-member carbon rings and one five member ring joined along common sides. The molecular formula is C19 H30 O2. It has a beta-isomer called epiandrosterone, in which an hydroxyl group occupies a different geometric position. 
 
The ratio of androsterone to epiandrosterone is thought to be important in how masculine behavior is interpreted by others Pheromones are well known in insect behavior. Their role in insect mating, navigation and nest protection has been studied, and active compounds have been isolated. Pheromones are the basis of some insect baits. Their effect on mammal behavior patterns is less well understood.
 

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Raw Medical Material Powder Priligy / Dapoxetine 119356-77-3

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Raw Medical Material Powder Priligy / Dapoxetine 119356-77-3
 
Dapoxetine Basic Info:
 
Product Name: Dapoxetine 
Synonyms: Priligy;Dapoxetine;Dapoxetine hydrochloride;Dapoxetine base;D-Dapoxetine HCL
CAS: 119356-77-3
MF: C21H23NO.ClH
MW: 341.88
EINECS: N/A
Purity: 99%
Appearance: White powder, odorless, slightly sweet, soluble in water and alcohol.
Product Categories: Erectile Dysfunction;API;Dapoxetine hydrochloride
  
Dapoxetine Description:
 
Premature ejaculation (PE) is the most common male sexual dysfunction. Dapoxetine hydrochloride, belonging to a class of drugs known as selective serotonin reuptake inhibitors or, was the first drug originally approved for the on-demand treatment of men with PE. We aimed to compare the intravaginal ejaculatory latency time (IELT), patient-reported global impression of change (PGIC), and adverse effect (AE) incidence associated with the use of dapoxetine (30 mg and 60 mg) versus placebo, and evaluate the differences in administering 60 mg versus 30 mg as on-demand medical oral therapy for the treatment of PE via a literature review and meta-analysis. Relevant randomized controlled trials (RCTs) were identified from PubMed, EMBASE, and Cochrane Central Register of Controlled Trials (Cochrane Library) databases. Ultimately, a total of seven RCTs with 8039 patients were included. Our meta-analysis demonstrated that dapoxetine (in the 30 mg and 60 mg subgroup) resulted in significantly higher IELT, PGIC, and AE incidence relative to the placebo, with higher proportions observed for 60 mg versus 30 mg of dapoxetine administration. The most common AEs were mild and tolerable. We conclude that dapoxetine (particularly the 60 mg dosage) may be considered a safe and effective drug for patients with PE.
 
Dapoxetine Application:
 
Dapoxetine hydrochloride is a drug that is used to treat premature ejaculation in men. It is available by prescription and is taken orally, prior to sexual intercourse. The drug belongs to the class called serotonin reuptake inhibitors (SSRIs), which have mainly been used to treat depression.
 
Sexual dysfunction, including premature ejaculation, is an extremely common condition worldwide. The cause of premature ejaculation has not been fully elucidated, but may include both psychological and physiological factors. Premature ejaculation refers to a short ejaculation time, which can affect the satisfaction of both partners during sexual intercourse.
 

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Ropivacaine Hydrochloride Ropivacaine Hcl 132112-35-7 Local Anesthetic Raw Material

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Ropivacaine Hydrochloride Ropivacaine Hcl 132112-35-7 Local Anesthetic Raw Material
 
Ropivacaine HCL Basic Info.:
 
Product Name: Ropivacaine hydrochloride
Synonyms: S-ROPIVACAINE HCL;
CAS: 132112-35-7
MF: C17H26N2O.ClH.H2O
MW: 328.88
EINECS: N/A
Product Categories: Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals
use:anesthetic (local),Pharmaceutical raw materials
Packing:Foil bag or as requirments
 
Ropivacaine HCL Description:
 
Ropivacaine is a local anaesthetic drug belonging to the amino amide group. The name ropivacaine refers to both the racemate and the marketed S-enantiomer. 
 
Ropivacaine is an anesthetic (numbing medicine) that blocks the nerve impulses that send pain signals to your brain. 
Ropivacaine is used as a local (in only one area) anesthesia for a spinal block, also called an epidural. The medication is used to provide anesthesia during a surgery or C-section, or to ease labor pains. 
Ropivacaine may also be used for purposes not listed in this medication guide.
 
Ropivacaine HCL Applications:
 
(1) Surgical anesthesia:Epidural anesthesia (including epidural anesthesia during cesarean section);Local infiltration anesthesia.
(2) Acute pain control:For postoperative or labor analgesia continuous epidural infusion can be used can also be intermittent medication;Local infiltration anesthesia.
 

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S4 Most Effective Sarm Supplement Andarine Muscle Building Raw Steroids Powder 401900-40-1

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S4 Most Effective Sarm Supplement Andarine Muscle Building Raw Steroids Powder 401900-40-1
 
Andarine Basic Info:
 
Product name: Andarine
Synonyms: Andarine;S4;S-4;GTX-007
CAS No.: 401900-40-1
MF: C19H18F3N3O6
MW: 441.36
Purity: 99.92%
Product categories APIs; Amines; Aromatics; Chiral Reagents; Intermediates & Fine Chemicals; Pharmaceuticals; SARMS
Appearance: White crystalline powder
Natural Bodybuilding SARM Powder Andarine S4 GTX-007 High Purity CAS 401900-40-1
 
Andarine Description:
 
Selective androgen receptor modulators or SARMs are a novel class of androgen receptor ligands. They are intended to have the same kind of effects as androgenic drugs like anabolic steroids but be much more selective in their action, allowing them to be used for many more clinical indications than the relatively limited legitimate uses that anabolic steroids are currently approved for.
 
S-4 is an experimental or investigation-stage proprietary SARM research chemical developed by GTx Inc for treatment of benign prostatic hypertrophy, muscle wasting, and osteoporosis. S-4 is considered a partial agonist of the androgen receptors in target tissue. S-4 has less pronounced anabolic and androgenic compared to other SARMs. In trials treating BPH induced in animal models, S-4 reduced prostate weight as effectively as finasteride and without producing any reduction in muscle mass or other side effects common with androgen receptor binding compounds. Gao et al suggest that by binding to androgen receptors, S-4 prevents DHT from binding and activating, but bypasses the expected anti-androgenic effects that would occur from occupying androgen receptors due to the fact that S-4 itself is a partial agonist of androgen receptors. S-4 has also been shown to prevent bone loss, reduce body fat, and improve muscle strength and body composition in orchidectomized and ovariectomized rats.
 
Andarine Application:
 
S4 Andarine is an orally active partial agonist for androgen receptors. It is less potent in both anabolic and androgenic effects than other SARMs. In an animal model of benign prostatic hypertrophy, andarine was shown to reduce prostate weight with similar efficacy to finasteride, but without producing any reduction in muscle mass or anti-androgenic side effects.
 
Andarine Function:
 
1. 1/3 as androgenic as testosterone in muscle tissue.
2. Anabolic at doses above 50mg.
3. Great for strength.
4. Great for muscle hardness.
5. Great for enhanced vascularity.
6. Great for endurance (aerobic or anaerobic).
7. Accelerated fat loss above 50mg.
8. Joint healing effects.
 

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Safe Human Growth Hormone Peptide PT 141 Bremelanotide For Peptide Drum PT141 32780-32-8

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Safe Human Growth Hormone Peptide PT 141 Bremelanotide For Peptide Drum PT141 32780-32-8
 
PT 141 Basic Info.
 
Product Name: PT-141; PT141
CAS: 32780-32-8
MF: C50H69N15O10
MW: 1040.17736
Appearance: White powder
Water Content(Karl Fischer): ≤ 5.0%
Acetate Content(by HPLC): ≤ 15.0%
Amino Acid Composition: ± 10% of theoretical
Purity(by HPLC): ≥ 97.0%
Single Impurity(by HPLC): ≤ 1.0%
Peptide Content(by %N): ≥ 80%
Assay(By Anhydrous, Acetic Acid-free): 95.0~105.0%
Bacterial Endotoxins: ≤ 5EU/mg
Grade: Pharmceutical Grade
Storage: Shading, confined preservation
 
PT 141 Description:
 
PT-141 is a synthetic amino acid protein discovered during clinical trials using the Melanotan 2 for sunless tanning, photo-protection results from melanotans. Participants were documented as having experienced aphrodisiac reactions, leading to the further development PT-141. The melanocortin system targets receptors associated with desire through the melanocyte stimulating hormone paths that cross the blood-brain-barrier. Potentially the powerful sex-drug results feeling an aphrodisiac experience amplifying arousal pt141 reviews have shown the ability to increase libido effects of both men and women.
 
PT 141 Application:
 
PT-141 functions by activating the melanocortin receptor and MC4R namely. Bremelanotide originally was tested for nasal spray delivery but was discontinued after concerns about side effects. Bremelanotide PT141, as Melanotan II, may cause spontaneous arousal enhancing effect. Unlike other supplements, PT-141 results do not act on the vascular body, but directly increases desires through the nervous system.
 

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Safety Pure Amino Acid 3,5-Diiodo-L-Thyronine T2 Powder 1041-01-6

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Safety Pure Amino Acid 3,5-Diiodo-L-Thyronine T2 Powder 1041-01-6
 
3,5-Diiodo-L-Thyronine Basic Information:
 
Product Name: 3,5-Diiodo-L-Thyronine
Synonyms: T2;Diiodothyronine;3,5-Diiodo-L-Thyronine;3,5-Diiodothyronine;
CAS: 1041-01-6
MF: C15H13I2NO4
MW: 525.08
EINECS: 213-867-7
Melting point: 255-260°C (dec.)
Storage temp.: 2-8°C
Chemical Properties: Off-White Solid
Product Categories: Medicine intermediate;Amino Acids 13C, 2H, 15N;Amino Acids & Derivatives;Intermediates;Labeling and Diagnostics Reagents
Usage: Of interest for the early detection and treatment of congenital or drug-induced hypothyroidism.
 

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