Hormone drugs used in treating deficient hormone levels in body, thyroid problems, ovulation

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Sarms Powder Steroids Pirfenidone 53179-13-8 Anti Fibrosis

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Sarms Powder Steroids Pirfenidone 53179-13-8 Anti Fibrosis 
 
Pirfenidone Basic information
 
Product Name: Pirfenidone
Synonyms: 5-methyl-1-phenyl-2(1h)-pyridon;amr-69;PIRFENIDONE;5-METHYL-1-PHENYL-1H-PYRIDIN-2-ONE;5-METHYL-1-PHENYL-2(1H)-PYRIDINONE;5-METHYL-1-PHENYL-2-(1H)-PYRIDONE;5-Methyl-N-phenyl-2-1H-pyridone;Pirfenidone also see 5-Methyl-1-Phenyl-2(1H)-Pyridinone
CAS: 53179-13-8
MF: C12H11NO
MW: 185.22
EINECS: N/A
Melting point: 96-97°C
Storage temp.: Store at RT
Solubility: DMSO: ≥10 mg/mL, Soluble
Chemical Properties: Off-White Solid
Usage: Pirfenidone has demonstrated activity in multiple fibrotic conditions, including those of the lung, kidney and liver
Product Categories: Aromatics Compounds;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Cytokine signaling;Inhibitors.
 
Pirfenidone Description:
 
Pirfenidone (INN, BAN) is an anti-fibrotic drug for the treatment of idiopathic pulmonary fibrosis (IPF). It works by reducing lung fibrosis through downregulation of the production of growth factors and procollagens I and II.
 
It is a drug developed by several companies worldwide, including InterMune Inc. (now part of Roche), Shionogi Ltd., and GNI Group Ltd. In 2008, it was first approved in Japan for the treatment of IPF after clinical trials, under the trade name of Pirespa by Shionogi & Co. In October 2010, the Indian Company Cipla launched it as Pirfenex. In 2011, it was approved for use in Europe for IPF; it was approved in Canada in 2012 ; and was approved in the United States in October 2014 under the same name. In September 2011, the Chinese State Food and Drug Administration provided GNI Group Ltd with new drug approval of pirfenidone in China, and later manufacture approval in 2013 under the trade name of Etuary.
 
In 2014 it was approved in Mexico under the name KitosCell LP, indicated for pulmonary fibrosis and liver fibrosis.There is also a topical form created for the treatment of abnormal wound healing processes.
 
Pirfenidone Application:
 
In vitro, pirfenidone can inhibit the uterine flesh tumour cells and leiomyoma cells proliferation. Pirfenidone can inhibit the TGF - beta - 1 inducing fibroblast collagen formation. Inhibition of PDGF, FGF and TGF - beta - 1 inducing fibroblast proliferation. In hamster model, pirfenidone, taken by mouth, that can the prevention and treatment of pulmonary fibrosis . Pirfenidone can prevent the sclerosing peritonitis in rats induced by chemical, can also be keloid grafting for the treatment of nude mice. Pirfenidone 0.01 1 mg/ml can suppress the matrix and dose dependent manner serum stimulate uterine fibroids and leiomyoma cell DNA synthesis, the compound has no cytotoxic effect, has no effect on collagen mRNA level also. Pirfenidone in hamster pulmonary fibrosis model can reduce the disease before the collagen I mRNA level enhancement, reduce the level of the lung hydroxyproline and malondialadehyde and lung preserved ammonia acyl hydroxylase activity.
 

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Serilesine 1

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Sex Enhancement Medicine Avanafil For Treating Male Sexual Dysfunction 330784-47-9

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Sex Enhancement Medicine Avanafil For Treating Male Sexual Dysfunction 330784-47-9
 
Avanafil Basic Info:
 
Product Name: Avanafil
CAS: 330784-47-9
Molecular Formula: C23H26ClN7O3
Molecular Weight: 483.9506
Character: White to Off-White Cyrstalline Solid.
Assay: 99% min.
Store: Store at room temperature away from moisture, heat, and light.
Product Categories: Aromatics;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Inhibitor;Avanafil;Inhibitors
Usage: Used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor.
 
Avanafil Description:
 
Avanafil is a PDE5 inhibitor approved for erectile dysfunction by the FDA and EMA,it acts by inhibiting a specific phosphodiesterase type 5 enzyme which is found in various body tissues, but primarily in the corpus cavernosum penis and retina.Avanafil works the same way as the three other ED drugs currently on the market: Viagra, Cialis, and Levitra. All these drugs target an enzyme called PDE5,and avanafil appears to inhibit this enzyme more selectively than the other. It is absorbed quickly, reaching a maximum concentration in about 30-45 minutes. About two-thirds of the participants were able to engage in sexual activity within 15 minutes.Avanafil's most frequent side effect was headache, and the other common side effects included flushing and nasal congestion,this new drug may have fewer side effects.
 
Avanafil Application:
 
Avanafil is used to treat male sexual function problems such as impotence or erectile dysfunction,it is in a class of medications called phosphodiesterase inhibitors.Avanafil works by increasing blood flow to the penis to help a man get and keep an erection.This drug does not protect against sexually transmitted diseases such as HIV, gonorrhea and syphilis.To decrease your risk of infection, always use an effective barrier method during all sexual activity.
 

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Skin Lightening Hormone Peptide Nonapeptide-1 For Whitening 158563-45-2

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Skin Lightening Hormone Peptide Nonapeptide-1 For Whitening 158563-45-2
 
Nonapeptide-1 Basic Infor:
 
Product Name: Nonapeptide-1
Synonyms: Melanostatine-5;Nonapeptide-1;Melanostatine
CAS: 158563-45-2
MF: C61H87N15O9S
MW: 0
Product Categories: birth-giving pharm;Beauty peptide
 
Nonapeptide-1 Description:
 
Nonapeptide-1, also called Melanostatine 5, is a propriety peptide that was originally developed for its antimicrobial activities. Animal research has revealed, however, that nonapeptide-1 can inhibit the synthesis of melanin, which makes it of interest for treating certain skin conditions. Animal models suggest that nonapeptide-1 can reduce synthesis of melanin and help decrease skin pigmentation to a substantial degree.
 
Nonapeptide-1 is a skin lightening peptide, derived from the melanocyte stimulating hormone (MSH). It prevents the activity of tyrosine in the melanocytes, melanin synthesis inhibition and helps to even out your skin tone by lessening hyper-pigmentation. This process reduces the formation of unwanted pigmentation, allowing for the control over skin tone and brown spots.
 
Nonapeptide-1 Application:
 
Nonapeptide-1 is of primary research interest for its ability to reduce hyperpigmentation by inhibiting the action of tyrosinase in melanin-producing cells. The ability to regulate melanin production has potential application in a number of conditions, including photodamage of the skin.
 
Research also suggests that nonapeptide-1 may play a role in the central nervous system where it may act on both dopaminergic receptors and opioid receptors to modify pain signaling as well as behavior. Studies in mice support the idea that nonapeptide-1 may have central actions that affect behavior and pain.
 

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Spironolactone

Spironolactone is a synthetic 17-lactone drug that is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics, used primarily to treat heart failure, ascites in patients with liver disease, low-renin hypertension, hypokalemia, secondary hyperaldosteronism (such as occurs with hepatic cirrhosis), and Conn's syndrome (primary hyperaldosteronism).Spironolactone is a specific pharmacologic antagonist of aldosterone, acting primarily through competitive binding of receptors at the aldosterone-dependent sodium-potassium exchange site in the distal convoluted renal tubule. Spironolactone causes increased amounts of sodium and water to be excreted, while potassium is retained. Spironolactone acts both as a diuretic and as an antihypertensive drug by this mechanism.

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Sports Nutrition Bodybuilding Powder Branch Chain Amino Acid Bcaa 5589-96-8

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Sports Nutrition Bodybuilding Powder Branch Chain Amino Acid Bcaa 5589-96-8
 
1.Branched Chain Amino Acid Basic Details:
 
Product Name: BROMOCHLOROACETIC ACID (BCAA)
Synonyms: RARECHEM AL BO 2372;BROMOCHLOROACETIC ACID;BCAA;bromochloro-aceticaci;chlorobromoaceticacid;Branched Chain Amino Acid;BROMOCHLOROACETATE
CAS: 5589-96-8
MF: C2H2BrClO2
MW: 173.39
EINECS: 216-653-1
Melting point: 27.5 °C(lit.)
Boiling point: 210-212 °C767 mm Hg(lit.)
density: 1.985 g/mL at 25 °C(lit.)
refractive index: n20/D 1.51(lit.)
Fp: >230 °F
Storage temp.: 2-8°C
Product Categories: Chloro;500 Series Drinking Water Methods;BromoChemical Class;Chemical Class;ChloroEPA;Halogenated;Method 552;Chemical Synthesis;Organic Acids;Synthetic Reagents
 Branched Chain Amino Acid
BCAA, (Branched Chain Amino Acid), is a compose of three branched chain amino acids.
Composition: L-leucine, L-isoleucine, L-valine
Ratio: 2:1:1
Purity: 99%
Grade: Food Grade
Appearance: White crystals or crystalline powder
Usage: Nutrition supplement for bodybuilding
 
2.Branched Chain Amino Acid Description:
 
A branched-chain amino acid (BCAA) is an amino acid having aliphatic side-chains with a branch (a central carbon atom bound to three or more carbon atoms). Among the proteinogenic amino acids, there are three BCAAs: leucine, isoleucine and valine.Non-proteinogenic BCAAs include norvaline and 2-aminoisobutyric acid.
The three proteinogenic BCAAs are among the nine essential amino acids for humans, accounting for 35% of the essential amino acids in muscle proteins and 40% of the preformed amino acids required by mammals.
 
3.Branched Chain Amino Acid Function:
 
Help to growth lean muscle maximises
Help to recovey when Optimises post-workout
Help to maintenance of cells
Help to avoid muscle degeneation
Optimises post-workout recovey
 
4.BCAA Bodybuliding Application:
 
Musle Supplement--BCAA:
On the role of health supplements in fitness,We don't care before, But when we useing a month we will be exciting because of the effect,Successful fitness need hard exercise but also scientific diet and important nutrition supplement.
 
In recent years, branched-chain amino acid supplements have come back into vogue in the bodybuilding and fitness community, and with good reason. There's more research that supports the use of BCAAs than most other supplements on the market. While BCAA supplementation may be useful for gaining mass, I believe BCAAs are especially helpful for maintaining muscle mass while on a calorie-deficit diet. They're particularly useful for bodybuilding competitors who take their physiques to the lean extreme.
It's well established that branched-chain amino acids (particularly leucine) stimulate protein synthesis, and might do so to a greater extent than a normal protein on its own. BCAAs also increase synthesis of the cellular machinery responsible for carrying out the process of protein synthesis. Thus, BCAAs not only increase the rate of protein synthesis, but they also increase the cell's capacity for protein synthesis! Yep, you read that right.
 
BCAAs also work in your favor by reducing the rate of protein breakdown. They do this (primarily) by decreasing the activity of the components of the protein breakdown pathway, and also by decreasing the expression of several complexes involved in protein breakdown. (In this case, they decrease the amount of mRNA produced from the gene that codes for these components.)
 

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Steroid Hormone Nandrolone Phenylpropionate For Bodybuilding 62-90-8

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Steroid Hormone Nandrolone Phenylpropionate For Bodybuilding 62-90-8
Pharmaceutical Material Nandrolone Phenylpropionate 62-90-8
 
Nandrolone Phenylpropionate Basic Info.
 
Product Name: Nandrolone Phenylpropionate
CAS No.: 62-90-8
Molecular Formula: C27H34O3
Molecular weight: 406.56
EINECS: 200-551-9
Assay: 98%
Packing: Foil bag or tin.
Delivery: Express courier.
MOQ: 10 grams.
Appearance: White or almost white crystalline powder; Soluble in ethanol, slightly soluble in vegetable oil; Practically insoluble in water MP: 93~99
Usage: Pharmaceutical material, Steroid hormone, Anabolin. As a male hormone and anabolic hormones.
 
Nandrolone Phenylpropionate Description:
 
Nandrolone phenylpropionate is one of the most popular injectable steroids. It is basically Deca, with a shorter ester ( phenylpropionate instead of decanoate ester found in deca durabolin or nandrolone decanoate), resulting in quicker release into the bloodstream. Although its shorter ester means it will require more frequent injections than decanoate, the positive side is that the amount of effective nandrolone in the blood and its levels are more easilly contollable. It's popularity is likely due to the fact that nandrolone exhibits significant anabolic effects with minimal androgenic side effects.
 
Nandrolone Phenylpropionate Applications:
 
Use after surgery for chronic wasting disease, serious illness, and weak thin, infirm, osteoporosis, infantile dysplasia, aplastic anemia, etc.
In earlier years, the only pharmaceutical injectables that were both widely available to bodybuilders and economical. Estrogen control did not then exist. For this reason, Durabolin's low aromatizing properties were then quite useful. Durabolin therefore won wide popularity.
 

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Steroid Hormone Powder DHT Stanolone For Muscle Building Androstanolone 521-18-6

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Steroid Hormone Powder DHT Stanolone For Muscle Building Androstanolone 521-18-6 
 
Stanolone Basic Info.:
 
Product Name: Stanolone
Synonyms: Androstanolone;Stanolone;DHT
CAS: 521-18-6
MF: C19H30O2
MW: 290.44
EINECS: 208-307-3
Melting point: 178-183 °C
Assay: 99% min.
Storage temp.: Controlled Substance, -20°C Freezer
Chemical Properties: White Crystalline Solid
Usage: Anabolic steroid. Controlled substance
Product Categories: Steroids;Intermediates & Fine Chemicals;Pharmaceuticals;Steroid and Hormone;API
 
Stanolone Description:
 
Androstanolone binds to and activates specific nuclear receptors. This agent may be used for testosterone replacement therapy in hypogonadal men, in HIV-wasting syndrome, and in other conditions in order to increase nitrogen retention and fat-free muscle mass.
 
The main androgen which is secreted by the testes is of course testosterone. However, in most of the body, the androgenic sign is not carried through by testosterone. In these tissues inluding brain (CNS), skin, genitals - practically everything but muscle - the active androgen is actually dihydrotestosterone (DHT). 
 
Stanolone Applications:
 
Use for chronic wasting disease, osteoporosis, severe infection and trauma, burn, etc caused by the negative nitrogen balance, promote the growth of premature infants and immature, etc. The fracture is not easy to heal, hypercholesterolemia and postpartum depression can also be used.
 

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Steroids Hormone Female Use Estrone Estrogen Steroids 53-16-7

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Steroids Hormone Female Use Estrone Estrogen Steroids 53-16-7
 
Estrone Basic Info.
 
Product Name: Estrone 
Related Products: Ethisterone, Estradiol, Estriol, Formestane, Norethisterone
Purity: 99%
Molecular Formula: C18H22O2
Molecular Weigh: 270.371
CAS No: 53-16-7
EINECS: 200-164-5
Appearance: White or almost white powder
Solubility: Water: 0.03 g/L
Function: Hormones and Regulation of Endocrine Function of Drug
Storage: Shading, Confined Preservation
Package: Discreet Packing ways for your choice.
Delivery: Deliver out within 24 hours after payment.
Payment: West Union, Money Gram.T/T
 
Estrone Description:
 
Estrogen is a female hormone produced by the ovaries and placenta. Adrenal cortex also produces a 
small number of estrogen.
 
Female children after puberty, the ovaries begin to secrete estrogen to promote the vagina, uterus,
fallopian tubes and ovaries own development, while endometrial hyperplasia produce menstruation. 
Estrogen can promote the accumulation of subcutaneous fat, plump; Hyperplasia, nipple and areola 
become darker in color, and produces sexuality; Promote sodium and water retention in the body, such as bone calcium deposition.
 
Estrogen is a steroid compounds have a wide range of biological activity, it is not only to promote and 
maintain the female reproductive organs and secondary sexual characteristics of the physiological role, and the endocrine system, the cardiovascular system, the body's metabolism, bone growth and 
maturation, skin and other aspects have a significant impact.
 
Due to the secretion of estrogen, can nourish the skin, beautiful hair, and promote breast development 
increased, reflecting the graceful curve of the body. So estrogen for women to maintain their youth and 
women second feature essential trace elements. In addition to the beauty estrogen plays an important 
role, and human health are closely linked.
 
Menopausal syndrome, arteriosclerosis, cerebral vascular obstruction, osteoporosis, Alzheimer's disease, weary, back pain, sore shoulders, sex, irregular menstruation, irregular menstruation, amenorrhea, infertility, breast dysplasia, dry skin, yellowish, rough, loss of elasticity, wrinkles, melasma, etc., and the body is low estrogen secretion lead to endocrine disorders. As noted above, estrogen for women is a very important trace elements. But the body's secretion of estrogen declining with age. And in vitro estrogen can not be supplemented by food, this is because estrogen in the human or animal body can build 
yourself.
 
Estrone Application:
 
Estrone (E1, and also oestrone) is an estrogenic hormone secreted by the ovary as well as adipose tissue with the chemical name of 3-hydroxyestra-1,3,5(10)-triene-17-one and the chemical formula C18H22O2. Estrone is an odorless, solid crystalline powder, white in color with a melting point of 254.5 °C and a specific gravity of 1.23. Estrone is one of several natural estrogens, which also include estriol and estradiol. Estrone is the least abundant of the three hormones; estradiol is present almost always in the reproductive female body, and estriol is abundant primarily duringpregnancy.
 
Estrone is known to be a carcinogen for human females as well as cause breast tenderness or pain, nausea, headache, hypertension, and leg cramps. In men, estrone has been known to cause anorexia, nausea, vomiting, and erectile dysfunction.Estrone is relevant to health and disease states because of its conversion to estrone sulfate, a long-lived derivative. Estrone sulfate acts as a reservoir that can be converted as needed to the more active estradiol. It is the predominant estrogen in postmenopausal women.
 

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T3 Fat Loss Steroid 98% Liothyronine Sodium Herbal Weight Loss Powders 55-06-1

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T3 Fat Loss Steroid 98% Liothyronine Sodium Herbal Weight Loss Powders 55-06-1
Organic Herbal Weight Loss Powders For Tablet / Capsule Liothyronine Sodium 
 
Liothyronine Sodium Basic Info.
 
Product Name: Liothyronine Sodium
Alias : T3 Sodium Salt; T3,Na; Liothyronine Sodium; Liothyronine Sodium Salt; Cytomel T3 
CAS NO: 55-06-1
MF: C15H11I3NNaO4
MW: 672.96
Einecs No: 200-223-5
Purity: 99%
Melting point: 205°C (dec.)(lit.)
Alpha: 20°(c=2,alcohol/1.2N HCl)
Storage temp.: 2-8°C
Solubility: 4 M NH4OH in methanol: 125 g/5mL, clear, yellow-brown
Appearance: white to beige powder, almost tasteless.
Product Categories: Amino Acids & Derivatives;Intermediates & Fine Chemicals;Pharmaceuticals;Steroid and Hormone;Isolabel;Other APIs.
Usage: 
(1)One of the hormones produced by the thyroid gland that is involved in the maintenance of metabolic homeostasis. Also produced in peripheral tissues as the active metabolite of Thyroxine.
(2)Cytochrome P450 inhibitor, Ca antagonist, anesthetic (local)Product 
 
Liothyronine Sodium Description :
 
Triiodothyronine, also known as T3, is a thyroid hormone. It affects almost every physiological process in the body, including growth and development, metabolism, body temperature, and heart rate.
 
Production of T3 and its prohormone thyroxine (T4) is activated by thyroid-stimulating hormone (TSH), which is released from the pituitary gland. This pathway is regulated via a closed-loop feedback process: Elevated concentrations of T3, and T4 in the blood plasma inhibit the production of TSH in the pituitary gland. As concentrations of these hormones decrease, the pituitary gland increases production of TSH, and by these processes, a feedback control system is set up to regulate the amount of thyroid hormones that are in the bloodstream.
 
As the true hormone, the effects of T3 on target tissues are roughly four times more potent than those of T4.Of the thyroid hormone that is produced, just about 20% is T3, whereas 80% is produced as T4. Roughly 85% of the circulating T3 is later formed in the thyroid by removal of the iodine atom from the carbon atom number five of the outer ring of T4. In any case, the concentration of T3 in the human blood plasma is about one-fortieth that of T4. This is observed in fact because of the short half-life of T3, which is only 2.5 days.This compares with the half-life of T4, which is about 6.5 days.
 
Liothyronine Sodium Application:
 
High Purity Liothyronine sodium/Cytomel T3/3,3',5´╝Źtriiodothyronine sodium/CAS No: 55-06-1 200-223-5 Weight Loss Powders
Liothyronine is the most potent form of thyroid hormone. Chemically, it is nearly identical to triiodothyronine (T3). As such, it acts on the body to increase the basal metabolic rate, affect protein synthesis and increase the body's sensitivity to catecholamines (such as adrenaline) by permissiveness. The thyroid hormones are essential to proper development and differentiation of all cells of the human body. These hormones also regulate protein, fat, and carbohydrate metabolism, affecting how human cells use energetic compounds.
In comparison to levothyroxine (T4), liothyronine has a faster onset of action as well as a shorter biological half-life, which may be due to less plasma protein binding to thyroxine-binding globulin and transthyretin.
 
Physicians can use this instead of or in addition to levothyroxine (T4) for patients undergoing thyroid withdrawal. When a patient has thyroid cancer or Graves' disease, ablation therapy with radioactive iodine can be used to remove any trace thyroid tissue. For 131I therapy to be effective, the trace thyroid tissue must be avid to iodine. The best method is to starve the tissue of iodine but this can lead to hypothyroid symptoms for the patient. Withdrawal from levothyroxine can be done but it takes six weeks of withdrawal for the remaining thyroid tissue to be completely starved. Six weeks is needed owing to levothyroxine's long half life. Six weeks can be inconvenient for the patient and delay treatment. Liothyronine instead can be taken and withdrawn from for two weeks to starve the thyroid tissue. This is much safer and more convenient than levothyroxine.
 

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