Hormone drugs used in treating deficient hormone levels in body, thyroid problems, ovulation

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Tacrolimus FK-506 Pharmaceutical Intermediates Organ Transplant 104987-11-3

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Tacrolimus FK-506 Pharmaceutical Intermediates Organ Transplant  104987-11-3
 
Tacrolimus Basic info: 
 
Product Name: Tacrolimus
Synonyms: Tacrolimus;Fr900506;Prograf;Tsukubaenolide;FK-506;
CAS: 104987-11-3
MF: C44H69NO12
MW: 804.02
Purity: 99%
Melting Point: 113-115°C
Boiling Point: 871.7 °C at 760 mmHg
Solubility: DMSO: >3 mg/mL
Appearance: White Crystalline Powder
Storage temp.: −20°C
Storage: Store in a cool, dry place. Do not store in direct sunlight. Store in a tightly closed container.
Product Categories: Active Pharmaceutical Ingredients;Immunosuppressant.;Intermediates & Fine Chemicals;Pharmaceuticals;API;Chiral Reagents;Fujimycin, Prograf;antibiotic;Inhibitors.
Usage: FK-506 (Tacrolimus) is a macrolide immunosuppressive drug that is mainly used after allogeneic organ transplant to reduce the activity of the patient's immune system.
 
Tacrolimus Application: 
 
L Immunosuppression following transplantation It has similar immunosuppressive properties to ciclosporin, but is much more potent. Immunosuppression with tacrolimus was associated with a significantly lower rate of acute rejection compared with ciclosporin-based immunosuppression (30.7% vs 46.4%) in one study. Clinical outcome is better with tacrolimus than with ciclosporin during the first year of liver transplantation. Long term outcome has not been improved to the same extent. Tacrolimus is normally prescribed as part of a post-transplant cocktail including steroids, mycophenolate and IL-2 receptor inhibitors. Dosages are titrated to target blood levels. Typical starting doses for once daily tacrolimus are 0.15-0.20 mg/kg body weight.
 
Tacrolimus Interactions:
 
Also like cyclosporin it has a wide range of interactions, including that with grapefruit which increases plasma-tacrolimus concentration. Several of the newer class of antifungals, especially of the azole class (fluconazole, posaconazole) also increase drug levels by competing for degradative enzymes.
 
Ulcerative colitis: 
In recent years, tacrolimus has been used to suppress the inflammation associated with ulcerative colitis, a form of inflammatory bowel disease. Although almost exclusively used in trial cases only, tacrolimus has shown to be significantly effective in the suppression of outbreaks of UC.
 
Tacrolimus Dermatological Use: 
 
As an ointment, tacrolimus is used in the treatment of eczema, in particular atopic dermatitis. It suppresses inflammation in a similar way to steroids, and is equally as effective as a mid-potency steroid. An important advantage of tacrolimus is that, unlike steroids, it does not cause skin thinning (atrophy), or other steroid related side-effects.
 
It is applied on the active lesions until they heal off, but may also be used continuously in low doses (twice a week), and applied to the thinner skin over the face and eyelids[citation needed]. Clinical trials of up to one year have been conducted. Recently it has also been used to treat segmental vitiligo in children, especially in areas on the face.
 

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Teriparatide Acetate

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Tesamorelin Anabolic Androgenic Steroids Tesamorelin Intramuscular Injection 218949-48-5

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Tesamorelin Anabolic Androgenic Steroids Tesamorelin Intramuscular Injection 218949-48-5
 
Tesamorelin Basic Info.:
 
Product Name: Tesamorelin
Unit Size: 2 mg/vial 
Unit Quantity: 1 Vial 
C6H9O-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu-NH2
CAS: 218949-48-5
Molecular Formula: C211H366N72O67S1
Molecular Weight: 5135.89
Appearance: white powder
Purity (HPLC): ≥99.00%
Packing: According to every customer's requirement.
 
Tesamorelin Description:
 
Tesamorelin is a synthetic peptide consisting of all 44 amino acids of hGRF with the addition of a trans-3-Hexenoic acid group.Tesamorelin (also known as Egrifta) is a synthetic form of growth-hormone-releasing hormone which is used in the treatment of HIV-associated lipodystrophy.tendon fibroblasts in a dose-dependent manner as revealed by transwell filter migration assay. BPC 157 also dose dependently accelerated the spreading of tendon fibroblasts on culture dishes. The F-actin formation as detected by FITC-phalloidin staining was induced in BPC 157-treated fibroblasts. The protein expression and activation of FAK and paxillin were determined by Western blot analysis, and the phosphorylation levels of both FAK and paxillin were dose dependently increased by BPC 157 while the total amounts of protein was unaltered. In conclusion, BPC 157 promotes the ex vivo outgrowth of tendon fibroblasts from tendon explants, cell survival under stress, and the in vitro migration of tendon fibroblasts, which is likely mediated by the activation of the FAK-paxillin pathway.
 
Tesamorelin Applications:
 
1. Triptorelin raises testosterone levels by causing constant stimulation of the pituitary, it decreases pituitary secretion of gonadotropins luteinizing hormone (LH) and follicle stimulating hormone (FSH). 
 
2. Like other GnRH agonists, triptorelin may be used in the treatment of hormone-responsive cancers such as prostate cancer or breast cancer, precocious puberty,estrogen-dependent conditions (such as endometriosis or uterine fibroids), and in assisted reproduction.
 

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Testosterone Base

Testosterone Base
Alias: Test Base, TTE, Testosterone
CAS:58-22-0
MF:C19H28O2
MW:288.42
EINECS:200-370-5
Appearance: white crystalline odourless solid

Usage:
With maintenance of muscle strength and mass, maintain bone density and strength, refreshing and enhancing physical function.
a. Medical uses: for none of testosterone replacement therapy, treatment of male climacteric syndrome, impotence.
b. Sports use: to increase the amount of muscle. Some people use it to increase the number of muscles
c. Other uses: biochemical studies about natural male hormone, control male sex organs and development of male secondary sexual character and growth.

Supply steroid powder, test cypionate,trenbolone acetate,Dianabol,Anavar,Methenolone acetate,Sustanon 250 ,test enanthate,Oxandrolone,Boldenone Undecylenate,Tadalafil,Sildenafil Citrate,Oxymetholone,Stanozolol

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Testosterone Phenylproprionate

Testolent is the name given to testosterone with the phenylproprionate ester. This particular ester is a medium length ester that falls squarely between testosterone long ester (cypionate) and short ester (propionate). Injections of two to three times per week are appropriate for this steroid. As with any testosterone, Testolent will give the user more mass to the muscle, burn fat in the body, enhance libido, increase immunity and increase energy. All the usual side effects of testosterone can also be expected conversion to estrogen and DHT, gynocomastia and water-retention. Tel:00862781331422 Fax:00862781331422 Cel:+8615337164625 Skyepe:leslie(at)carphetin(dot)com Email:leslie(at)carphetin(dot)com

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Thymosin Alpha1 Acetate

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Thyroid Hormone L-Liothyronine Powders 6893-02-3

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Thyroid Hormone L-Liothyronine Powders 6893-02-3
 
L-Liothyronine Basic Info.
 
Product Name: L-Liothyronine
Synonyms: T3;O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine;Cytomel;L-Liothyronine
CAS: 6893-02-3
MF: C15H12I3NO4
MW: 650.97
EINECS: 229-999-3
Purity: 99%
Melting point: 234-238 °C(lit.)
Alpha: 23°(c=2 in ethanol)
Storage temp.: −20°C
Chemical Properties: Off-White Solid
Product Categories: Amino Acids & Derivatives;Intermediates & Fine Chemicals;Labeling and Diagnostics Reagents;Pharmaceuticals;Inhibitors;Stable Isotopes.
Usage: One of the hormones produced by the thyroid gland that is involved in the maintenance of metabolic homeostasis. Also produced in peripheral tissues as the active metabolite of Thyroxine.
 
L-Liothyronine Description :
 
Triiodothyronine, also known as T3, is a thyroid hormone. It affects almost every physiological process in the body, including growth and development, metabolism, body temperature, and heart rate.
 
Production of T3 and its prohormone thyroxine (T4) is activated by thyroid-stimulating hormone (TSH), which is released from the pituitary gland. This pathway is regulated via a closed-loop feedback process: Elevated concentrations of T3, and T4 in the blood plasma inhibit the production of TSH in the pituitary gland. As concentrations of these hormones decrease, the pituitary gland increases production of TSH, and by these processes, a feedback control system is set up to regulate the amount of thyroid hormones that are in the bloodstream.
 
As the true hormone, the effects of T3 on target tissues are roughly four times more potent than those of T4.Of the thyroid hormone that is produced, just about 20% is T3, whereas 80% is produced as T4. Roughly 85% of the circulating T3 is later formed in the thyroid by removal of the iodine atom from the carbon atom number five of the outer ring of T4. In any case, the concentration of T3 in the human blood plasma is about one-fortieth that of T4. This is observed in fact because of the short half-life of T3, which is only 2.5 days.This compares with the half-life of T4, which is about 6.5 days.
 
L-Liothyronine Application:
 
High Purity Liothyronine sodium/Cytomel T3/3,3',5´╝Źtriiodothyronine sodium/CAS No: 55-06-1 200-223-5 Weight Loss Powders
Liothyronine is the most potent form of thyroid hormone. Chemically, it is nearly identical to triiodothyronine (T3). As such, it acts on the body to increase the basal metabolic rate, affect protein synthesis and increase the body's sensitivity to catecholamines (such as adrenaline) by permissiveness. The thyroid hormones are essential to proper development and differentiation of all cells of the human body. These hormones also regulate protein, fat, and carbohydrate metabolism, affecting how human cells use energetic compounds.
In comparison to levothyroxine (T4), liothyronine has a faster onset of action as well as a shorter biological half-life, which may be due to less plasma protein binding to thyroxine-binding globulin and transthyretin.
 
Physicians can use this instead of or in addition to levothyroxine (T4) for patients undergoing thyroid withdrawal. When a patient has thyroid cancer or Graves' disease, ablation therapy with radioactive iodine can be used to remove any trace thyroid tissue. For 131I therapy to be effective, the trace thyroid tissue must be avid to iodine. The best method is to starve the tissue of iodine but this can lead to hypothyroid symptoms for the patient. Withdrawal from levothyroxine can be done but it takes six weeks of withdrawal for the remaining thyroid tissue to be completely starved. Six weeks is needed owing to levothyroxine's long half life. Six weeks can be inconvenient for the patient and delay treatment. Liothyronine instead can be taken and withdrawn from for two weeks to starve the thyroid tissue. This is much safer and more convenient than levothyroxine.
 

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Top Quality Loss Weight Peptide Adipotide For Fat Burn

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Top Quality Loss Weight Peptide Adipotide For Fat Burn
 
Adipotide Basic Info.:
 
Product Name: Adipotide
Place of origin: China
Routine use of Storage: 2-8°C
Molecular Formula: C111H204N36O28S2
Molar Mass: 2555.22 g/mol
Appearance: White powder
Purity: 99%+
Lead time: Customized
Mini Order: 2mg
Usage: The King of Weight Loss
Brand Name: KaFen
 
Adipotide Description:
 
What is Adipotide?
Aditpotide is an experimental weight loss peptidomimetic with the amino acid sequence CKGGRAKDC-GG-D(KLAKLAK)2, which has been developed by researchers in the United States in an effort to fight obesity. Peptidomimetics are small protein-like chains designed to mimic a peptide. The peptide called Adipotide has been developed by U.S. researchers in the fight against the obesity . This experimental treatment has reduced by 11% the weight of the treated monkeys by reducing fatty tissue, the BMI, and waist circumference.
 
For Anti-Obesity
Pathological studies have shown that obesity serves a risk factor for a myriad of diseases such as cancer, hypertension, endocrine disorders (such as diabetes mellitus, hyperlipidemias and metabolic syndrome), cardiovascular disease (such as stroke and myocardial infarctions) and degenerative diseases (such as osteoarthritis). Moreover, aberrant accumulation of white adipocytes predisposes the affected individual to lipoma and lipomatosis. It is well known that abdominal adiposity is mainly caused by white adipocytes, and this form of adiposity is the most lipolytically active, thus requiring a steady blood supply. Any interference with the blood supply causes it to activate the apoptotic process.
 

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Trimegestone

Trimegestone is a steroidal progestin of the 19-norprogesterone group related to promegestone. Trimegestone has very high affinity for the progesterone receptor, only weak affinity for the mineralocorticoid receptor, and little or no affinity for other steroid hormone receptors. It is used as a hormonal contraceptive and in hormonal replacement therapy for postmenopausal symptoms.

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USP Sex Enhance Amino Tadalafil 385769-84-6 For Breast Cancer

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USP Sex Enhance Amino Tadalafil 385769-84-6 For Breast Cancer
 
Amino Tadalafil Basic Info.:
 
Product Name: Amino Tadalafil
Synonyms: Amino Tadanafil
CAS: 385769-84-6
MF: C21H18N4O4
MW: 0
EINECS: N/A
Melting point: 280-282°C
storage temp.: -20°C Freezer
Chemical Properties: White Solid
Usage: A drug analog of Tadalafil
Product Categories: Drug Analogues;Intermediates & Fine Chemicals;Pharmaceuticals
 
Amino Tadalafil Description:
 
A high-pressure liquid chromatography-diode array detection and multi-mode ionization tandem mass spectrometry (HPLC-DAD-MMI-MS/MS) method was used to identify amino-tadalafil and rimonabant in electronic cigarette (e-cigarette) cartridges. Amino-tadalafil is a drug analogue of the commercially approved ™ (i.e. tadalafil). Rimonabant is a drug that was, at one time, approved for weight loss in Europe (although approval has been retracted), but not in the United States. In addition, poor quality control over the e-cigarette products analyzed here is shown by the presence of nicotine in products labeled as containing no nicotine or by the presence of significant amounts of rimonabant oxidative degradant in e-cigarette products containing rimonabant. Identification was accomplished by comparing the retention time of relevant peaks in the sample with those of standard compounds, in addition to comparison of the UV spectra, mass spectra and/or product ion mass spectra.
 
Function Of Amino Tadalafil:
 
Made of natural soybean oil residue extraction. Is the cell membrane of the active material, especially exists in the brain cells.
The main function is to improve the function of nerve cells, adjust the transmission of nerve impulses, enhance memory function, due to its strong lipotropy, absorbed quickly through the blood brain barrier into the brain, help relax vascular smooth muscle cells, increase the role of brain blood flow.
 

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