Hormone drugs used in treating deficient hormone levels in body, thyroid problems, ovulation

chemical-categories

Polypeptide Hormone Follistatin 315 Antibody Fst-315

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Polypeptide Hormone Follistatin 315 Antibody Fst-315
 
Follistatin 315 Basic Info.
 
Product Name: Follistatin 315 / Fst-315
Specification: 1mg/vial
Purity: 85%+
Appearance: White powder
Specific Optical Rotation (c=0.5,10% HAc): -50.0~-60.0°
Water Content(Karl Fischer): ≤5.0%
Acetate Content(by HPLC): ≤15.0%
Amino Acid Composition: ±10% of theoretical
Purity (by HPLC): ≥98.0%
Single Impurity(by HPLC): ≤1.0%
Peptide Content(by %N): ≥80%
Assay(By Anhydrous, Acetic Acid-free ) :95.0~105.0%
Bacterial Endotoxins: ≤5EU/mg
Storage/Stability: Stored at -20 °C if preferred. Storage in frost-free freezers is not recommended.
Note: This product is furnished for LABORATORY RESEARCH USE ONLY. Not for diagnostic or therapeutic use.
 
Description of Follistatin 315:
 
Follistatin is being studied for its role in regulation of muscle growth in mice, as an antagonist to myostatin (also known as GDF-8, a TGF superfamily member) which inhibits excessive muscle growth. Lee & McPherron demonstrated that inhibition of GDF-8, either by genetic elimination (knockout mice) or by increasing the amount of follistatin, resulted in greatly increased muscle mass.In 2009, research with macaque monkeys demonstrated that regulating follistatin via gene therapy also resulted in muscle growth and increases in strength. This research paves the way for human clinical trials, which are hoped to begin in the summer of 2010 on Inclusion body myositis.
A study has also shown that increased levels of follistatin, by leading to increased muscle mass of certain core muscular groups, can increase life expectancy in cases of spinal muscular atrophy (SMA) in animal models.
It is also being investigated for its involvement in polycystic ovary syndrome (PCOS), though there is debate as to its direct role in this infertility disease.
 
Follistatin 315 Application:
 
Follistatin 315 primary function is the binding and bioneutralization of members of the TGF-β superfamily, with a particular focus on activin, a paracrine hormone.
 
Storage Instruction
Store at +4°C or at -20°C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
 

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Budesonide Powder Inhalation Antiasthmatic 51333-22-3

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Budesonide Powder Inhalation Antiasthmatic 51333-22-3
 
Budesonide Basic Info.:
 
Product Name: Budesonide
Synonyms: Dexbudesonide;TriaMcinolone-D5;Preferid;Pulmicort;Spirocort;S-1320;Rhinocort;Bidien;Cortivent.
CAS: 51333-22-3
MF: C25H34O6
MW: 430.5339
EINECS: 257-139-7
Assay: 99.5%
Density: 1.27g / cm3
Boiling point: 599.7 °C at 760 mmHg
Flash Point: 201.8 °C
Melting point: 221-232°C (dec.)
Storage temp.: Store at RT, Ventilated, low-temperature ,dry storeroom.
Appearance: White Solid
Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals;Steroids
Usage: 
(1)A non-halogenated glucocorticoid related to triamcinolone hexacetonide. Used as an antiinflammatory agent
(2)laxative, antineoplastic
(3)The oral capsule is used for the treatment of mild to moderate active Crohn's disease. The oral tablet is used for induction of remission in patients with active, mild to moderate ulcerative colitis. The oral inhalation formulation is used for the treatme.
 
Budesonide Attribute:
 
Budesonide is a glucocorticoid steroid for the treatment of asthma, COPD and non-infectious rhinitis (including hay fever and other allergies), and for treatment and prevention of nasal polyposis. In addition, it is used for inflammatory bowel disease. It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.
 
Budesonide Effect:
 
Budesonide is nebulized for maintenance and prophylactic treatment of asthma. also for treatment and prevention of nasal polyposis. maintenance of remission (for up to 3 months) of Crohn's disease (mild-to-moderate) involving the ileum and/or ascending colon. Budesonide assists in the induction of remission in patients with active ulcerative colitis.
 

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Muscle Building Oral Sarms Powder Rad 140 1182367-47-0

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Muscle Building Oral Sarms Powder Rad 140 1182367-47-0
 
RAD 140 Basic Info:
 
Product Name: RAD 140
CAS: 118237-47-0
MF: C20H16ClN5O2
MW: 393.826
Purity: 99.5%(HPLC)
Apprarance: White crystalline powder
 
Product Description Of RAD 140:
 
RAD140 is a highly effective, oral SARM (Selective Androgen Receptor Modulator) currently being studied for both anabolic and neuroprotective effects. It is in a class of androgen receptor (AR) ligands that are tissue selective, developed to treat muscle wasting associated with cancer, acute and chronic illness and age-related muscle loss. Recent research of RAD140 shows superior lean tissue selectivity, and reduced androgenic side effects when compared to competing SARM compounds. This compound provides is being studied for neuroprotection as well; an important neural action of endogenous androgens that is relevant to neural health and resilience to neurodegenerative diseases, and to be as effective as testosterone in reducing cell death induced by apoptotic insults. Easy to dose oral SARM that increases lean mass while remaining tissue selective in current research Added value for research with pronounced neuroprotective properties Myotrophic and neuroregeneration research compound.
 
Application Of RAD 140:
 
According to the Cambridge-based pharmaceuticals company Radius, the potent, orally bioavailable and nonsteroidal RAD 140 SARM is designed to make the hormonal receptors in the tissues of the body act the same way as if they're getting a good dose of testosterone, setting off the same effects as if you're cycling with prohormones and anabolic steroids minus unwanted side effects.
 
Moreover, clinical studies also show that RAD 140 SARM also has a few other benefits, which we will discuss more thoroughly in a moment.
 
Enhanced speed, stamina and endurance during high-intensity workoutsFaster buildup of muscular tissues that helps you achieve more gains in a shorter period of timeBased on medical tests, RAD 140 SARM also displayed a greater anabolic effect than testosterone when used. Researchers pointed out that besides having a more "reinforced" effect than testosterone, RAD 140 SARM was also seen to help reduce the androgenic side effects that can be potentially caused by the same on the prostate.
 

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Top Quality Loss Weight Peptide Adipotide For Fat Burn

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Top Quality Loss Weight Peptide Adipotide For Fat Burn
 
Adipotide Basic Info.:
 
Product Name: Adipotide
Place of origin: China
Routine use of Storage: 2-8°C
Molecular Formula: C111H204N36O28S2
Molar Mass: 2555.22 g/mol
Appearance: White powder
Purity: 99%+
Lead time: Customized
Mini Order: 2mg
Usage: The King of Weight Loss
Brand Name: KaFen
 
Adipotide Description:
 
What is Adipotide?
Aditpotide is an experimental weight loss peptidomimetic with the amino acid sequence CKGGRAKDC-GG-D(KLAKLAK)2, which has been developed by researchers in the United States in an effort to fight obesity. Peptidomimetics are small protein-like chains designed to mimic a peptide. The peptide called Adipotide has been developed by U.S. researchers in the fight against the obesity . This experimental treatment has reduced by 11% the weight of the treated monkeys by reducing fatty tissue, the BMI, and waist circumference.
 
For Anti-Obesity
Pathological studies have shown that obesity serves a risk factor for a myriad of diseases such as cancer, hypertension, endocrine disorders (such as diabetes mellitus, hyperlipidemias and metabolic syndrome), cardiovascular disease (such as stroke and myocardial infarctions) and degenerative diseases (such as osteoarthritis). Moreover, aberrant accumulation of white adipocytes predisposes the affected individual to lipoma and lipomatosis. It is well known that abdominal adiposity is mainly caused by white adipocytes, and this form of adiposity is the most lipolytically active, thus requiring a steady blood supply. Any interference with the blood supply causes it to activate the apoptotic process.
 

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98% Purity Aicar 2627-69-2 Sarms White Solid Raw Material

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98% Purity Aicar 2627-69-2 Sarms White Solid Raw Material
 
Aicar Basic Info:
 
Product Name: Aicar
CAS: 2627-69-2
MF: C9H14N4O5
MW: 258.23
EINECS: 220-097-5
Assay: 99%
Product Categories: Carbohydrates & Derivatives;Nucleotides;Protein Kinase;Cardiovascular;
Chemical Properties: White or off-white solid
 
Product Description Of Aicar:
 
Aicar is a peptide whose technical name is 5-Aminoimidazole-4-carboxamide ribonucleotide.
It can also be known as AICA ribonucleotide, ZMP, or Acadesine. It is an intermediate contained in the generation of inosine monophosphate. It primarily functions as an AMP-activated protein kinase agonist, meaning that it has the ability to promote the operation of nutrient stores for energy production. It has a molecular mass of 338.211, and it has a molecular formula of C9H15N4O8P.
 
Aicar is an adenosine analog that selectively activates AMP-activated protein kinase (AMPK). AMPK regulates lipid and glucose metabolism to maintain cellular energy homeostasis (Hardie and Carling).
 
Aicar can play a hand in boosting these processes because it contains the ability to penetrate cardiac
cells and block the production of enzymes tied to regulating glucose intake and energy expulsion. With these regulatory enzymes inhibited, the affected cells can in turn boost the amount of glucose that can be received, and it can also increase its level of energy conversion. Additionally, the peptide’s presence has been determined to aid in lowering programmed cell death, a process that is also known as apoptosis.
 
Aicar Application:
 
Glucose uptake stimulant; AMPK activator.AICAR is a nucleoside analogue that is able to enter
nucleoside pools and is able to significantly increase levels of adenosine during periods of ATP
breakdown. Adenosine-regulating agents (ARAs) hav e been recognized for therapeutic potential
in myocardial ischemia. Cardioprotective.
 
Aicar is a nucleoside analogue that is able to enter nucleoside pools and is able to significantly increase levels of adenosine during periods of ATP breakdown. Adenosine-regulating agents (ARAs) hav e been recognized for therapeutic potential in myocardial ischemia. Cardioprotective.
Biological Activity Cell-permeable, allosteric activator of AMP-activated protein kinase (AMPK). Augments proliferation, differentiation and mineralization of osteoblastic MC3T3-EI cells and attenuates psychosine-induced expression of proinflammatory cytokines and iNOS in astrocytes.
 
Aicar is a peptide whose technical name is 5-Aminoimidazole-4-carboxamide ribonucleotide. It can also be known as AICA ribonucleotide, ZMP, or Acadesine. It is an intermediate contained in the generation of inosine monophosphate. It primarily functions as an AMP-activated protein kinase agonist, meaning that it has the ability to promote the operation of nutrient stores for energy production. It has a molecular mass of 338.211, and it has a molecular formula of C9H15N4O8P.
 
Aicar Function:
 
Aicar is an adenosine analog that selectively activates AMP-activated protein kinase (AMPK). AMPK regulates lipid and glucose metabolism to maintain cellular energy homeostasis (Hardie and Carling).
 
Aicar can play a hand in boosting these processes because it contains the ability to penetrate cardiac cells and block the production of enzymes tied to regulating glucose intake and energy expulsion. With these regulatory enzymes inhibited, the affected cells can in turn boost the amount of glucose that can be received, and it can also increase its level of energy conversion. Additionally, the peptide's presence has been determined to aid in lowering programmed cell death, a process that is also known as apoptosis.
 

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99.6% Purity Estrogen Female Hormone Estradiol CAS 50-28-2

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99.6% Purity Estrogen Female Hormone Estradiol CAS 50-28-2
 
Estradiol Basic Info.:
 
Product Name: Estradiol
Synonyms: Estradiol
CAS No.: 50-28-2 
Formula: C18H24O2 
Molecular Weight: 272.39 
EINECS: 200-023-8 
Density: 1.17 g/cm3 
Melting Point: 178-179 °C(lit.) 
Boiling Point: 445.917 °C at 760 mmHg 
Flash Point: 209.634 °C 
Purity: 99% 
Application: Pharmaceutical Intermediates 
Appearance: White crystalline powder 
Function and use: It is a kind of estrogen, can promote and regulate the normal development of women's genitals and secondary. Can cause hyperplasia of mammary gland carcinoma development, but in larger doses, can inhibit pituitary prolactin release, and reduce the secretion of milk. 
 
Estradiol Description:
 
Estradiol (o) estradiol C18H24O2 being a sex hormone. With alpha, beta, two types of alpha physiological function is strong. Steiner, winter (Wintersteiner et al. 1935) was extracted from the horse urine pregnancy, moreover also can cause from the urine, placenta, pig ovary, etc. There is also a male horse testis or urine. Because it has the very strong sex role, so that it or its ester is, in fact, ovarian secretion of the sex hormones of the most important. Estradiol benzoate is decided to one of the international unit of sex hormone titer standard substance and used.
 
Function and use: It is a kind of estrogen, can promote and regulate the normal development of women's genitals and secondary. Can cause hyperplasia of mammary gland carcinoma development, but in larger doses, can inhibit pituitary prolactin release, and reduce the secretion of milk. Potent mammalian estrogenic hormone produced by the ovary.
 
Estradiol Application:
 
Both men and women produce estrogen hormones. Estrogens are responsible for female sexual development and function, such as breast development and the menstrual cycle. In women, estrogens are produced mainly in the ovaries and in the placenta during pregnancy. Small amounts are also produced by the adrenal glands. In men, small amounts of estrogens are produced by the adrenal glands and testicles. Small amounts of estrone are made throughout the body in most tissues, especially fat and muscle. This is the major source of estrogen in women who have gone through menopause.
 
Estradiol acts primarily as a growth hormone for the reproductive structures including the lining of the vagina, the fallopian tubes, the endometrium and the cervical glands. The hormone is also required to maintain oocytes (eggs in the ovary) and triggers a series of events that lead to ovulation. In addition, estradiol works in conjunction with progesterone to prepare the womb lining for implantation. In males, estradiol aids sperm maturation and also helps to maintain a healthy libido.
 

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Factory Supplying Peptide Lyophilized Powder Peg MGF (2mg)

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Factory Supplying Peptide Lyophilized Powder Peg MGF (2mg)
 
MGF Basic Info.:
 
Product Name: MGF ( Mechano Growth Factor )
2mg*10vial/kit
Synonyms: MGF;Anti-STAT5A, C-Terminal antibody produced in rabbit;Mammary gland factor;STA5A;Anti-STAT5A antibody produced in rabbit;STAT5, His tagged human;STAT5A
CAS No.: N/A
Molecular Formula: C121H200N42O39
Molecular Weight: 2867.2
Storage temp.: -20°C
Form: lyophilized powder
Sequence: Tyr-Gln-Pro-Pro-Ser-Thr-Asn-Lys-Asn-Thr-Lys-Ser-Gln- Arg-Arg-Lys-Gly-Ser-Thr-Phe-Glu-Glu-Arg-Lys-NH2
 
MGF Description:
 
PEGylation is the act of attaching a Polyethylene glycol (PEG) structure to another larger molecule (in this case, MGF). The PEG acts as a protective coating and the theory here is that this will allow the MGF to be carried through the blood stream without being broken down. Neurological research has shown that utilizing PEGylated MGF resulted in a longer more stable acting version of the MGF peptide in serum/blood.
 
MGF Application:
 
Using PEG MGF on cycle or off cycle, you are going to experience recovery that is far superior to any generic peptide available. Just like normal peptides, remember that PEG MGF comes in the form of a white delicate powder that needs to be reconstituted with bacteriostatic water and kept in the refrigerator.
 
PEG MGF Dosage:
 
Typical dosage of PEG-MGF is between 200mcg. - 400mcg. per week but many bodybuilders have said to "research" this peptide at dosages exceeding 1,500 mcg weekly with no adverse effects.
Because PEG MGF can cause site specific muscle growth, it is recommended to inject PEG MGF bi-laterally to ensure symmetrical gains. The most effective test results were experienced in users injecting the PEG MGF post exercise.
 

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Factory Supplying Peptide Lyophilized Powder Peg MGF (5mg)

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Factory Supplying Peptide Lyophilized Powder Peg MGF (5mg)
 
MGF Basic Info.:
 
Product Name: MGF ( Mechano Growth Factor )
Synonyms: MGF;Anti-STAT5A, C-Terminal antibody produced in rabbit;Mammary gland factor;STA5A;Anti-STAT5A antibody produced in rabbit;STAT5, His tagged human;STAT5A
CAS No.: N/A
Molecular Formula : C121H200N42O39
Molecular Weight : 2867.2
Storage temp.: -20°C
Form: lyophilized powder
Sequence: Tyr-Gln-Pro-Pro-Ser-Thr-Asn-Lys-Asn-Thr-Lys-Ser-Gln- Arg-Arg-Lys-Gly-Ser-Thr-Phe-Glu-Glu-Arg-Lys-NH2
Packing: 5mg/vial
 
MGF Description:
 
PEGylation is the act of attaching a Polyethylene glycol (PEG) structure to another larger molecule (in this case, MGF). The PEG acts as a protective coating and the theory here is that this will allow the MGF to be carried through the blood stream without being broken down. Neurological research has shown that utilizing PEGylated MGF resulted in a longer more stable acting version of the MGF peptide in serum/blood.
 
MGF Application:
 
Using PEG MGF on cycle or off cycle, you are going to experience recovery that is far superior to any generic peptide available. Just like normal peptides, remember that PEG MGF comes in the form of a white delicate powder that needs to be reconstituted with bacteriostatic water and kept in the refrigerator.
 
PEG MGF Dosage:
 
Typical dosage of PEG-MGF is between 200mcg. - 400mcg. per week but many bodybuilders have said to "research" this peptide at dosages exceeding 1,500 mcg weekly with no adverse effects.
Because PEG MGF can cause site specific muscle growth, it is recommended to inject PEG MGF bi-laterally to ensure symmetrical gains. The most effective test results were experienced in users injecting the PEG MGF post exercise.
 

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High Purity Gw-501516 GW501516 For Weight Loss 317318-70-0

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High Purity Gw-501516 GW501516 For Weight Loss 317318-70-0
 
GW 501516 Basic Info:
 
Product Name: GW501516
Alias: Cardarine
CAS No.: 317318-70-0
Molecular Formula: C21H18F3NO3S2
Molecular Weight: 453.50
Purity: 99%
Grade: Pharmaceutical Grade
Appearance: White Powder
Usage: Fat loss
Dose: The recommended dosage for GW is 10-20 mg and for 8 weeks length
 
GW 501516 Description:
 
GW501516 is the name of a Glaxo Wellcome drug (the GW stands for the company and the number
is that of the product). It is also known as GW-501,516, GW1516, GSK-516).
 
GW-501516 is a selective agonist with high affinity and it is very potent. Various studies on this
PPAR receptor in lab rats indicates that it regulates the various proteins that the body uses for
energy. Rats with high fat and low metabolism were given the product and they were able to
lose weight and to increase overall energy levels.
 
GW 501516 Application:
 
GW501516 (also known as GW-501,516, GW1516, GSK-516 and on the black market as Endurobol) is a PPARδ receptor agonist that was invented in a collaboration between Ligand Pharmaceuticals and GlaxoSmithKline in the 1990s, was entered into clinical development as a drug candidate for metabolic diseases and cardiovascular diseases, and was abandoned in 2007 because animal testing showed that the drug caused cancer to develop rapidly in several organs.
 
In 2007 research was published showing that high doses of GW501516 given to mice dramatically improved their physical performance; the work was widely discussed in popular media, and led to a black market for the drug candidate and to its abuse by athletes as a doping agent. The World Anti-Doping Agency (WADA) developed a test for GW501516 and other related chemicals and added them to the prohibited list in 2009; it has issued additional warnings to athletes that GW501516 is not safe.
 
History Of GW 501516:
 
Concerns were raised prior to the 2008 Beijing Olympics that GW501516 could be used by athletes as an ergogenic performance-enhancing drug that was not currently controlled by regulations or detected by standard tests. One of the main researchers from the study on enhanced endurance consequently developed a urine test to detect the drug, and made it available to the International Olympic Committee. The World Anti-Doping Agency (WADA) developed a test for GW501516 and other related PPARδ modulators,and added such drugs to the prohibited list in 2009.
 
GW501516 has been promoted on bodybuilding and athletics websites and by 2011 had already been available for some time on the black market. In 2011 it was reported to cost $1000 for 10 g.In 2012, WADA recategorised GW501516 from a gene doping compound to a "hormone and metabolic modulator".
 

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Muscle Building Steroids Powder Epistane Methyl E 4267-80-5

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Muscle Building Steroids Powder Epistane Methyl E 4267-80-5
 
Epistane Basic Info.
 
Product name: Epistane
Alias: Methyl Epitiostanol
Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals;Steroids;Sulfur & Selenium Compounds
CAS: 4267-80-5
M.F.: C20H32OS
Assay: 98%
M.P.: 168-169°C
Appearance: White powder
Package: foil bag
Usage: Epistane is a methylated derivative of the steroid epitiostanol (E588800). Epistane is a readily orally active compound that lacks the 3-ketone common to most anabolic steroids. Epistane greatly incr eases protein synthesis and build up in lean muscle mass
 
Epistane Description:
 
Epistane, exhibits a strong, long lasting anti-estrogen effect that is organ tissue specific. This means it works only where you want it to work. Broad range estrogen blockers and aromatase inhibitors can result in system shut down, aching joints, and decreased IGF-I expression. Epistane binds specifically to the 17-estradiol receptor protein in the target tissues. Because of its long lasting and strong effects on specific tissue,
 
Epistane can significantly reduce and reverse the effects of gynocomastia because not only does Epistane specifically block estrogen in breast tissue but it induces an estrogen-depleted condition which leads to apoptosis or the death of the breast tissue cells. Studies show that small doses of the parent compound, Epitiostanol, at just 10-20mg/week showed a complete disappearance of the mass and pain in 25% of the male patients in the clinical trail, while the other 75% of the patients showed at least a 50% reduction in the mass and complete loss of pain in just 4-8 weeks. Thats results in 100% of the male users with no side effects.
 
Epistane is more than an anti-estrogen, though, as it also binds to androgen receptors in skeletal muscle. As a PRO-Anabolic compound Epistane promotes increases in strength and lean body mass with an anabolic/androgenic value (Q ratio) of 12. With most powerful androgens there is a high risk of the natural suppression of the gonads. Epistane, unlike other PRO-Anabolic compounds that have recently been released, is relatively mild on the gonads and, due to the anti-estrogenic effects and the fact that Epistane keeps LH levels elevated, post cycle therapy becomes a breeze.
 
Application Of Epistane:
 
Epistane is a DHT derived prohormone that was brought to market by RPN with their product "Havoc. " Epistane is an anti-estrogenic dry compound that will aid users in adding lean muscle mass as well as cutting fat. In addition to this, Epistane does not aromatize and is non-progestagenic. This basically means that while on Epistane, estrogen related side effects like gyno and progesterone related side effects like sensitive breast tissue are virtually non-existent. Users will experience little to no side effects while on Epistane, making it an ideal beginner prohormone.
 
Epistane Function:
 
Epistane also binds to androgen receptors in skeletal muscle cells and muscle stem cells. This leads to changes in muscle cell function and protein synthesis. In the case of muscle stem cells, which will actually change and fuse with your active adult skeletal muscles increasing the muscles potential for growth and repair. On the opposite side, the presence of androgens actually decreases the ability of stem cells to form new fat cells. So now have increased stem cell conversion to muscle cells and decrease the conversion of stem cells to fat cells, giving you more positive effects of nutrition and training.
 

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