chemical-categories

 

Mk-677 Oral Grow Hormone Sarm Ibutamoren Mesylate 159752-10-0

 

MK-677 Basic Info.:

 

Product Name: Ibutamoren Mesylate ( MK-677 )

Synonyms: MK-677; Crescendo; IbutaMoren Mesylate; MK-667; IBUTAMORIN; Nutrobal

CAS: 159752-10-0

MF: C27H36N4O5S.CH4O3S

MW: 624.776

Purity: 99%

Boiling Point: 868.9°C at 760 mmHg

Appearance: white powder

Storage temp.: 2-8°C

Product Categories: SARMs(Selective androgen receptor modulator)

Application: active growth secretagpgie, mk-677 Effective for age -related fraity Active.

 

MK-677 Description:

 

Nutrobal (Mk-677) is an orally administrated growth hor secretagogue originally developed by Reverse Pharmacology. A secretagogue is the term for a substance that chemically signals for the pituitary gland to secrete growth hor . In other words, Nutrobal could be compared to peptides like GHRP-6 or Ipamorelin, only it doesn't require any injections nor does it have any side effects like GHRP-6. This GHS (Growth Hormone Secretagogue) was developed in an aim to combat such conditions as muscle wasting, obesity and osteoporosis. It was also targeted towards treatment of elderly hip fracture patients, so there are a myriad of studies done on safety.

 

Ibutamoren (MK-677, L-163,191) is a drug which acts as a potent, orally active secretagogue,mimicking the GH stimulating action of the endogenous hormone ghrelin.It has been demonstrated to increase the release of, and producessustained increases in plasma levels of several hormones including , but without affecting cortisol levels.

 

It is currently under development as a potential treatment for reduced levels of these hormones, such as

in deficient children or elderly adults, and human studies have shown it to increase both muscle mass

and bone mineral density, making it a promising therapy for the treatment of frailty in the elderly.It also

alters metabolism of body fat and so may have application in the treatment of obesity.Some mk-677 study shows the suggested mk-677 dosage is 25mgs-50mgs when it is the oral.

 

MK-677 Application:

 

Produced by Reverse Pharmacology, MK 677 (Nutrobal) is an orally administered growth hormone secretagogue that is designed to stimulate the pituitary gland to release growth hormones. In case you're

wondering, "secretagogue" is basically a natural substance that causes another substance to be

secreted, such as gastrin.

 

MK 677 (Nutrobal) was originally formulated to keep health problems like osteoporosis, obesity and

muscle wasting, but has been seen to promote an increase in lean body mass as well as a boost in

IGF-1 serum concentration during clinical runs.

 

Moreover, here are the positive effects of MK 677 (Nutrobal) in terms of improving growth hormone

pulse intensity:Inhibits the signaling of somatostatin receptors.Slows down the activity of somastostatin in the system.Improves somatotroph signaling in growth hormone releasing hormones (GHRH).Amplifies and increases the overall production and release of GHRH.

 

 

Steroids Hormone Female Use Estrone Estrogen Steroids 53-16-7

 

Estrone Basic Info.

 

Product Name: Estrone 

Related Products: Ethisterone, Estradiol, Estriol, Formestane, Norethisterone

Purity: 99%

Molecular Formula: C18H22O2

Molecular Weigh: 270.371

CAS No: 53-16-7

EINECS: 200-164-5

Appearance: White or almost white powder

Solubility: Water: 0.03 g/L

Function: Hormones and Regulation of Endocrine Function of Drug

Storage: Shading, Confined Preservation

Package: Discreet Packing ways for your choice.

Delivery: Deliver out within 24 hours after payment.

Payment: West Union, Money Gram.T/T

 

Estrone Description:

 

Estrogen is a female hormone produced by the ovaries and placenta. Adrenal cortex also produces a 

small number of estrogen.

 

Female children after puberty, the ovaries begin to secrete estrogen to promote the vagina, uterus,

fallopian tubes and ovaries own development, while endometrial hyperplasia produce menstruation. 

Estrogen can promote the accumulation of subcutaneous fat, plump; Hyperplasia, nipple and areola 

become darker in color, and produces sexuality; Promote sodium and water retention in the body, such as bone calcium deposition.

 

Estrogen is a steroid compounds have a wide range of biological activity, it is not only to promote and 

maintain the female reproductive organs and secondary sexual characteristics of the physiological role, and the endocrine system, the cardiovascular system, the body's metabolism, bone growth and 

maturation, skin and other aspects have a significant impact.

 

Due to the secretion of estrogen, can nourish the skin, beautiful hair, and promote breast development 

increased, reflecting the graceful curve of the body. So estrogen for women to maintain their youth and 

women second feature essential trace elements. In addition to the beauty estrogen plays an important 

role, and human health are closely linked.

 

Menopausal syndrome, arteriosclerosis, cerebral vascular obstruction, osteoporosis, Alzheimer's disease, weary, back pain, sore shoulders, sex, irregular menstruation, irregular menstruation, amenorrhea, infertility, breast dysplasia, dry skin, yellowish, rough, loss of elasticity, wrinkles, melasma, etc., and the body is low estrogen secretion lead to endocrine disorders. As noted above, estrogen for women is a very important trace elements. But the body's secretion of estrogen declining with age. And in vitro estrogen can not be supplemented by food, this is because estrogen in the human or animal body can build 

yourself.

 

Estrone Application:

 

Estrone (E1, and also oestrone) is an estrogenic hormone secreted by the ovary as well as adipose tissue with the chemical name of 3-hydroxyestra-1,3,5(10)-triene-17-one and the chemical formula C18H22O2. Estrone is an odorless, solid crystalline powder, white in color with a melting point of 254.5 °C and a specific gravity of 1.23. Estrone is one of several natural estrogens, which also include estriol and estradiol. Estrone is the least abundant of the three hormones; estradiol is present almost always in the reproductive female body, and estriol is abundant primarily duringpregnancy.

 

Estrone is known to be a carcinogen for human females as well as cause breast tenderness or pain, nausea, headache, hypertension, and leg cramps. In men, estrone has been known to cause anorexia, nausea, vomiting, and erectile dysfunction.Estrone is relevant to health and disease states because of its conversion to estrone sulfate, a long-lived derivative. Estrone sulfate acts as a reservoir that can be converted as needed to the more active estradiol. It is the predominant estrogen in postmenopausal women.

 

 

USP Sex Enhance Amino Tadalafil 385769-84-6 For Breast Cancer

 

Amino Tadalafil Basic Info.:

 

Product Name: Amino Tadalafil

Synonyms: Amino Tadanafil

CAS: 385769-84-6

MF: C21H18N4O4

MW: 0

EINECS: N/A

Melting point: 280-282°C

storage temp.: -20°C Freezer

Chemical Properties: White Solid

Usage: A drug analog of Tadalafil

Product Categories: Drug Analogues;Intermediates & Fine Chemicals;Pharmaceuticals

 

Amino Tadalafil Description:

 

A high-pressure liquid chromatography-diode array detection and multi-mode ionization tandem mass spectrometry (HPLC-DAD-MMI-MS/MS) method was used to identify amino-tadalafil and rimonabant in electronic cigarette (e-cigarette) cartridges. Amino-tadalafil is a drug analogue of the commercially approved ™ (i.e. tadalafil). Rimonabant is a drug that was, at one time, approved for weight loss in Europe (although approval has been retracted), but not in the United States. In addition, poor quality control over the e-cigarette products analyzed here is shown by the presence of nicotine in products labeled as containing no nicotine or by the presence of significant amounts of rimonabant oxidative degradant in e-cigarette products containing rimonabant. Identification was accomplished by comparing the retention time of relevant peaks in the sample with those of standard compounds, in addition to comparison of the UV spectra, mass spectra and/or product ion mass spectra.

 

Function Of Amino Tadalafil:

 

Made of natural soybean oil residue extraction. Is the cell membrane of the active material, especially exists in the brain cells.

The main function is to improve the function of nerve cells, adjust the transmission of nerve impulses, enhance memory function, due to its strong lipotropy, absorbed quickly through the blood brain barrier into the brain, help relax vascular smooth muscle cells, increase the role of brain blood flow.

 

 

High Quality Anti-Estrogen Steroids Raloxifene HCl 82640-04-8 

 

Raloxifene HCL Basic Info.:

 

Product Name: Raloxifene Hydrochloride

Synonyms: Raloxifene HCL;Raloxifene Hydrochloride;Ly156758;Piperidin;Keoxifene;Keoxifene Hydrochloride;Ly 139481;AKOS 92138

CAS: 82640-04-8

MF: C28H28ClNO4S

MW: 510.04

Melting Point: 250-253°C

Storage Temp.: -20°C Freezer

Solubility DMSO: 28 mg/mL, soluble

Chemical Properties: Light-Yellow Solid

Assay: 99%

Grade: Pharmaceutical Grade

Product Categories: Active Pharmaceutical Ingredients;Raloxifene;Intracellular receptor;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;Pharmaceutical intermediate;API;Inhibitors;antifungal

Usage: amino acid, nutrient, Labeled Raloxifene, intended for use as an internal standard for the quantification of Raloxifene by GC- or LC-mass spectrometry.A nonsteroidal, selective estrogen receptor modulator (SERM). Antiosteoporotic.

 

Product Description:

 

Raloxifene HCL(marketed as Evista) is an oral selective estrogen receptor modulator (SERM) that has estrogenic actions on bone and anti-estrogenic actions on the uterus and breast. It is used in the prevention of osteoporosis in postmenopausal women and to reduce the risk of invasive breast cancer in postmenopausal women with osteoporosis and in postmenopausal women at high risk for invasive breast cancer.

 

This drug is different from hormones (including estrogens and progestins). It works by acting like estrogen (as a selective estrogen receptor modulator or SERM) in some parts of the body. Raloxifene HCL helps to preserve bone mass, but it does not affect the breast and uterus like estrogen or relieve symptoms of menopause such as hot flashes.

 

Raloxifene HCL is indicated for the treatment and prevention of osteoporosis in postmenopausal women. It is also used for reduction of risk and treatment of invasive breast cancer, and it also reduces breast density.For either osteoporosis treatment or prevention, supplemental calcium and/or vitamin D should be added to the diet if daily intake is inadequate.

 

Raloxifene HCL is used to prevent and treat bone loss (osteoporosis) in women after menopause. Maintaining strong bones by slowing bone loss helps to reduce the risk of fractures.

 

Raloxifene HCL may also lower the chance of getting a certain type of breast cancer (invasive) in women after menopause.

 

 

Lidocaine HCL 73-78-9 Natural Procaine Lidocaine Hydrochloride

 

Lidocaine HCL Basic Info.:

 

Product name: Lidocaine HCl

Alias: Lidocaine Hydrochloride

CAS No.: 73-78-9

Molecular Formula: C14H23ClN2O

Molecular Weight: 270.8

EINECS: 200-803-8

Appearance: White crystalline powder

Melting point: 80-82°C

Usage: To enhance the growing of man genitals.

 

Product Description Of Lidocaine HCL:

 

Lidocaine, as a local anesthetic, is characterized by a rapid onset of action and intermediate duration of efficacy. Therefore, lidocaine is suitable for infiltration, block and surface anesthesia. Longer-acting substances such as bupivacaine are sometimes given preference for subdural and epidural anesthesias. Lidocaine, on the other hand, has the advantage of a rapid onset of action. It can stop Epinephrine  vasoconstricts arteries form bleeding, and it can also delays the resorption of lidocaine, almost doubling the duration of anaesthesia. For surface anesthesia several formulations are available that can be used e. G. For endoscopies, before intubations etc. Buffering the pH of lidocaine makes local freezing less painful. Lidocaine drops can be used on the eyes for short ophthalmic procedures.

 

Lidocaine HCL Applications:

 

Topical lidocaine has been shown in some patients to relieve the pain of postherpetic neuralgia (a complication of shingles), though there is not enough study evidence to recommend it as a first-line treatment. IV lidocaine also has uses as a temporary fix for tinnitus. Although not completely curing the disorder, it has been shown to reduce the effects by around two thirds.

Lidocaine hydrochloride injection administered intravenously or intramuscularly, is specifically indicated in the acute management of ventricular arrhythmias such as those occurring in relation to acute myocardial infarction, or during cardiac manipulation, such as cardiac surgery.

 

 

Male Enhancement 4-Androstenedione 63-05-8 For Muscle Building

 

Androstenedione Basic Info.

 

Product Name: Androstenedione

Synonyms: 4-Androstenedione;4AD;3,17-Dioxoandrost-4-Ene;delta-(sup4)-Androsten-3,17-dione;delta(Sup4)-Androstene-3,17-dione;delta4-androsten-3,17-dione;delta-4-androstenedione;SKF 2170;skf2170;4-AD

CAS: 63-05-8

MF: C19H26O2

MW: 286.41

EINECS: 200-554-5

Purity: 98.88%

Manufacturer: Kafen

Characters: Near white crystalline powder, soluble in ethanol, insoluble in water

 

Androstenedione Applications:

 

Testo-ster-one precursor and metabolite with androgenic activity. Controlled substance (anabolic steroid); Simplified hormone drugs, from the testis or urine extracted with the role of a male hormone steroids, norethisterone, testosterone propionate in the middle body, is widely used in small rheumatoid arthritis, diuretic, and a variety of contraceptive to control infectious inflammation.

 

Androstenedione Description:

 

4-Androstenedione can be synthesized in one of two ways. The primary pathway involves conversion of 17-hydroxypregnenolone to dehydroepiandrosterone by way of 17,20-lyase, with subsequent conversion of dehydroepiandrosterone to 4-Androstenedione via the enzyme 3-β-hydroxysteroid dehydrogenase. The secondary pathway involves conversion of 17-hydroxyprogesterone, most often a precursor to cortisol, to 4-androstenedione directly by way of 17,20-lyase. Thus, 17,20-lyase is required for the synthesis of 4-androstenedione, whether immediately or one step removed.  

 

The production of adrenal 4-Androstenedione is governed by ACTH, whereas production of gonadal 4-Androstenedione is under control by gonadotropins. In premenopausal women, the adrenal glands and ovaries each produce about half of the total 4-androstenedione(about 3 mg/day). After menopause, 4-androstenedione production is about halved, due primarily to the reduction of the steroid secreted by the ovary. Nevertheless, 4-androstenedione is the principal steroid produced by the postmenopausal.

 

 

Manufacturer Terlipressin Acetate With High Quality 14636-12-5

 

Terlipressin Acetate Basic Info.:

 

Product Name: Terlipressin Acetate

Synonyms: Terlipressin;Terlipressin Acetate;Terilipressin;

CAS: 14636-12-5

MF: C52H74N16O15S2

MW: 1227.37

EINECS: 238-680-8

Product Categories: Amino Acid Derivatives;Peptide;hormones

Usage: Terlipressin is an analogue of vasopressin used as a vasoactive drug in the management of hypotension. Terlipressin is used norepinephrine-resistant septic shock and hepatorenal syndrome. Terlipressin is also used in the treatment of acute variceal bleeding.

 

Terlipressin Acetate Pharmacological Effects:

 

Terlipressin is a novel long-acting synthetic vasopressin reagent,its chemical name is three glycyl lysine vasopressin, it is a prodrug, itself has no activity ,in vivo  , it removes three glycyl residues in its N-terminus by aminopeptidase, and slowly "releases" the active lysine vasopressin. It is this "slow release" mechanism that makes it maintain the smooth muscle contraction up to 10 hours after a single administration, whereas the same dose of vasopressin, it can maintain its activity for 20-40 minutes. On the other hand,because of the slow digestion,  lysine vasopressin in the circulation cannot reach toxic levels, and usage of  terlipressin is safer.

Pharmacological effect of terlipressin is splanchnic vascular smooth muscle contraction, and reduction of visceral blood flow (such as reducing blood flow in the mesentery, spleen, uterus, etc.), thereby reducing portal vein blood flow,and reducing portal pressure, on the other hand it may also reduce plasma renin concentration, thereby increasing the renal blood flow in patients with hepatorenal syndrome, to improve kidney function, and increase urine output. Terlipressin is currently the only drug which is able to increase mortality in patients with esophageal varices bleeding , it is previously mainly used in clinical for the treatment of variceal bleeding, in addition,terlipressin now has also been successfully used for liver and kidney integrated syndrome and refractory shock, it is also likely to play a useful role in the cardiopulmonary resuscitation . Compared with vasopressin, it has a lasting effect, and it does not cause dangerous complications, including promoting  fibrinolysis and severe complications in the cardiovascular systems, and the use of it is simple (available intravenous injection), it is more suitable for rescue and treatment of emergent and critical  patients.

 

Terlipressin Acetate Mechanism of Action:

 

Terlipressin, a synthetic triglycyl-lysine derivative of vasopressin, is a inactive prodrug. It has pressor and antidiuretic effects. Following IV injection, lysine vasopressin are released following the enzymatic cleavage of 3 glycyl moieties.

Duration: 4-6 hr.

 

 

White Ghrp-2 Human Growth Hormone For Bodybuilding 158861-67-7

 

GHRP 2 Basic Info.:

 

Product name: GHRP-2 (GHRP-2 Acetate )

Synonym: Pralmorelin; GHRP2; D-Alanyl-3-(2-naphthalenyl)-D-alanyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysinamide; GHRP 2; 

CAS: 158861-67-7

MF: C45H55N9O6

MW: 817.9749

Purity: 98%

Appearance: White powder

Density: 1.27g/cm3

Boiling point: 1265.3°C at 760 mmHg

Flashing point: 719°C

Function: To stimulate GH secretion, appetite, and to gain weight

 

GHRP 2 Description:

 

GHRP-2 is a synthetic agonist of ghrelin, the newly-discovered gut peptide which binds to the GH secretagogue receptor. Ghrelin has two major effects, stimulating both GH secretion and appetite/meal initiation. GHRP-2 has been extensively studied for its utility as a GHS. Since the test subjects body will end up producing more GH this way, fat will be reduced while lean muscle mass is increased. Along with this, IGF-1 levels will increase, as well, along with the different hypothalamus functions.

 

GHRP 2 Application:

 

GHRP-2 basically acts exactly like ghrelin. It can induce food consumption just like ghrelin and stimulate GH secretion, too. When infused, GHRP-2 makes the GH levels in the body increase a lot and it can induce cell cAMP secretion the way that GRF tends to, as well.

GHRP-2 as a Growth Hormone Secretagogue

 

GHRP-2 has been studied extensively for its utility as a growth hormone secretagogue (GHS). Scientists have discovered that the Growth Hormone Releasing Peptide-2 increases the natural production of growth hormone (GH). In the early 90’s, one of the most famous studies was performed and later published in 1997 in the Journal of Endocrinology and Metabolism. This study further exemplifies the theory that growth hormone releasing peptides (including Ipamorelin and GHRP-6) could help hormone deficient adults and children. Ever since these major scientific studies, GHRP-2 has been widely produced. With other scientific labs confirming the results from their studies, GHRP-2 can in fact work for those who lack the ability to make adequate human growth.

 

 

99% Active Pharmaceutical Ingredient Lorcaserin CAS 616202-92-7

 

Lorcaserin Basic Info.:

 

Product name: Lorcaserin

CAS No.: 616202-92-7

M.F.: C11H14ClN

M.W.: 195.6886

Purity: 99.5%

Appearance: White crystal

Use: Medicine reducing weight and antidepressants.

 

Product Description Of Lorcaserin: 

 

The U.S. Food and Drug Administration approved Belviq (lorcaserin hydrochloride), as an addition to a reduced-calorie diet and exercise, for chronic weight management.

lorcaserin (Belviq) works by activating the serotonin 2C receptor in the brain. Activation of this receptor may help a person eat less and feel full after eating smaller amounts of food.

 

Lorcaserin Superiority: 

 

We promise most of powders are in stock and free samples are available. We have Professional team special for package and shipment and staring on tracking code 24hours for customs pass guaranteed. High quality, reasonable price and fast and Safety delivery is always our pursuit. It is certainly that warm after-sale service for you. Any of your question would be solved for the first as soon as Possible.

 

 

99% High Purity Prohormones Steroids Raw Powder Estriol 50-27-1

 

Estriol Basic Info.:

 

Product Name: Estriol

CAS No.: 50-27-1

Formula: C18H24O3

Molecular Weight: 288.39

EINECS: 200-022-2

Density: 1.255 g/cm3

Melting Point: 280-282 °C(lit. )

Boiling Point: 469 °C at 760 mmHg

Flash Point: 220.8 °C

Purity: 99%

Appearance: White crystalline powder

 

Estriol Description:

 

Estradiol, or more precisely, 17β-estradiol, is a human sex hormone and steroid, and the primary female sex hormone. It is named for and is important in the regulation of the estrous and menstrual female reproductive cycles. Estradiol is essential for the development and maintenance of female reproductive tissues but it also has important effects in many other tissues including bone. While estrogen levels in men are lower compared to women, estrogens have essential functions in men as well. Estradiol is found in most vertebrates as well as many crustaceans, insects, fish, and other animal species.

 

Estradiol or oestradiol (American or British English usages), derives from estra-, Gk. οστρο? (oistros, literally meaning "verve or inspiration") and -diol, a chemical name and suffix indicating that this form of steroid and sex hormone is a type of alcohol bearing two hydroxyl groups.

 

Estradiol is produced especially within the follicles of female ovaries, but also in other endocrine (i.e., hormone-producing) and non-endocrine tissues (e.g., including fat, liver, adrenal, breast, and neural tissues). Estradiol is biosynthesized from progesterone (arrived at in two steps from cholesterol, via intermediate pregnenolone). One principle pathway then converts progesterone to its 17-hydroxy-derivative, and then to androstenedione via sequential cytochrome P450-catalyzed oxidations.Action of aromatase on this dione generates estrone, and action of a dehydrogenase on this gives the title compound, 17β-estradiol.

 

Estriol Application:

 

Hormonal contraception:

A chemical derivative of estradiol, ethinyl estradiol with maximum dosage 200 µg, is a major component of hormonal contraceptive devices. Combined forms of hormonal contraception contain ethinyl estradiol and a progestin, which both contribute to the inhibition of GnRH, LH, and FSH, which accounts for the ability of these birth control methods to prevent ovulation and thus prevent pregnancy. Other types of hormonal birth control contain only progestins and no ethinyl estradiol.

 

Hormone replacement therapy:

If severe side effects of low levels of estradiol in a woman's blood are experienced (commonly at the beginning of menopause or after oophorectomy), hormone replacement therapy may be prescribed. Such therapy is usually combined with a progestin to reduce the risk of endometrial cancer.

 

Estrogen therapy may be used in treatment of infertility in women when there is a need to develop sperm-friendly cervical mucus or an appropriate uterine lining. This is often prescribed in combination with clomifene.

 

Estrogen therapy can also be used to treat advanced prostate cancer, as well as to relieve symptoms of breast cancer.

Not all products are available worldwide. Estradiol is also part of conjugated estrogen preparations, such as Premarin, though it is not the major ingredient. (Premarin consists of a large number of estrogen derivatives. As the name indicates, it comes from pregnant mares' urine.

 

Hormone replacement therapy in transgender women:

Main article: Hormone replacement therapy (male-to-female)

Estrogen therapy is also used as part of the hormone replacement therapy for trans women. Either oral or transdermal estradiol is used in higher concentrations during initial treatment and transition; estradiol is continued in lower doses to maintain female-level hormones following gender reassignment surgery.

 

Estriol Blocking Estrogens:

Inducing a state of hypoestrogenism may be beneficial in certain situations where estrogens are contributing to unwanted effects, e.g., certain forms of breast cancer, gynecomastia, premature closure of epiphyses, and inhibiting feminization in female-to-male transsexual hormone treatment. Estrogen levels can be reduced by inhibiting production using gonadotropin-releasing factor agonists (GnRH agonists) or blocking the aromatase enzyme using an aromatase inhibitor, or with an estrogen receptor antagonist.