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Leukotrienes

Leukotrienes are fatty signaling molecules and eicosanoids that were originally isolated from leukocytes. Leukotrienes use both autocrine signaling and paracrine signaling to regulate the body's response. Leukotrienes are powerful inflammatory lipid mediators derived from the 5-lipoxygenase (5-LO) cascade of arachidonic acid. Leukotrienes are synthesized via 5-lipoxygenase metabolism of arachidonic acid by mast cells and basophils during the early-phase response to antigen and by eosinophils and macrophages during the late phase. The Leukotrienes levels in nasal secretions are elevated after short-term allergen instillation and in allergy season in patients with allergic rhinitis. Leukotrienes are of different types- LTA4,LTB4, LTC4, LTD4, LTE4, and LTF4. Leukotrienes act principally on a subfamily of G protein-coupled receptors. They may also act upon peroxisome proliferator-activated receptors. Leukotrienes are involved in asthmatic and allergic reactions and act to sustain inflammatory reactions. Several leukotriene receptor antagonists such as montelukast and zafirlukast are used to treat asthma. Leukotrienes are very important agents in the inflammatory response.

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Levothyroxine

Levothyroxine is a synthetically prepared levo isomer of thyroxine, the major hormone secreted from the thyroid gland. It is used as a hormone replacement for patients with thyroid problems. It is used to treat hypothyroidism, goiter, chronic lymphocytic thyroiditis, myxedema coma, and stupor.

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Lidocaine HCL 73-78-9 Natural Procaine Lidocaine Hydrochloride

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Lidocaine HCL 73-78-9 Natural Procaine Lidocaine Hydrochloride
 
Lidocaine HCL Basic Info.:
 
Product name: Lidocaine HCl
Alias: Lidocaine Hydrochloride
CAS No.: 73-78-9
Molecular Formula: C14H23ClN2O
Molecular Weight: 270.8
EINECS: 200-803-8
Appearance: White crystalline powder
Melting point: 80-82°C
Usage: To enhance the growing of man genitals.
 
Product Description Of Lidocaine HCL:
 
Lidocaine, as a local anesthetic, is characterized by a rapid onset of action and intermediate duration of efficacy. Therefore, lidocaine is suitable for infiltration, block and surface anesthesia. Longer-acting substances such as bupivacaine are sometimes given preference for subdural and epidural anesthesias. Lidocaine, on the other hand, has the advantage of a rapid onset of action. It can stop Epinephrine  vasoconstricts arteries form bleeding, and it can also delays the resorption of lidocaine, almost doubling the duration of anaesthesia. For surface anesthesia several formulations are available that can be used e. G. For endoscopies, before intubations etc. Buffering the pH of lidocaine makes local freezing less painful. Lidocaine drops can be used on the eyes for short ophthalmic procedures.
 
Lidocaine HCL Applications:
 
Topical lidocaine has been shown in some patients to relieve the pain of postherpetic neuralgia (a complication of shingles), though there is not enough study evidence to recommend it as a first-line treatment. IV lidocaine also has uses as a temporary fix for tinnitus. Although not completely curing the disorder, it has been shown to reduce the effects by around two thirds.
Lidocaine hydrochloride injection administered intravenously or intramuscularly, is specifically indicated in the acute management of ventricular arrhythmias such as those occurring in relation to acute myocardial infarction, or during cardiac manipulation, such as cardiac surgery.
 

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Liothyronine sodium

T3 in the body is responsible for regulating the uptake of various nutrients into cells and into the mitochondria of those cells in order to effectively become utilized for the production and consumption of energy. The mitochondria of every single cell in the body utilizes carbohydrates (primarily), fat, and even protein for the production of an energy source known as ATP (Adenosine Triphosphate). Through the intake of more T3, this production of ATP will increase, leading to an increased rate of energy consumption in the form of fats, carbohydrates, and protein. Hence, this is why the consumption of too much T3 without the use of anabolic steroids can result in muscle loss. The bodybuilding and athletic world is attracted to the use of T3 as a physique and/or performance enhancing drug because of its capability to distinctly boost the body?s metabolism in the effort to metabolize body fat at a greater rate. T3 is traditionally utilize during cutting, dieting, and/or pre-contest phases of training due to the universal goal of these phases to break down body fat, though in recent years Cytomel has gained some popularity as a useful agent during bulking and mass gaining phases of training (normally in conjunction with anabolic steroids) in order to better efficiently process nutrients and/or to keep body fat levels down during periods of higher caloric intake. Cytomel (T3) is commonly used with anabolic steroids due to its significant impact on the body?s metabolism as a whole. It is very important to understand that T3 is indiscriminate in its metabolism boosting properties ? it will increase the metabolism of fats, carbohydrates, and protein all equally. Therefore, beyond a particular dose of T3, there is an increased risk of muscle loss through increased turnover of protein. Through the use of anabolic steroids and a properly adjusted diet, this muscle loss as a result of T3 can be prevented as a result of the nitrogen-retaining and protein sparing properties of theanabolic steroids. Cytomel (T3) is also commonly combined with other fat loss agents in order to increase its overall effect, as it does work synergistically with other fat loss agents. Tel:00862781331422 Fax:00862781331422 Cel:+8615337164625 Skype:leslie(at)carphetin(dot)com Email:leslie(at)carphetin(dot)com

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Lipotropin

Lipotropin is a hormone produced by the cleavage of pro-opiomelanocortin.It stimulates fat burning and is present at the release of endorphins. Lipotropin supplements are in a class of growth hormones that may be taken to increase muscle mass and decrease body fat.Lipotropin stimulates hGH and thus slows the aging process.It is offered in liquid form to be sprayed under the tongue for immediate, effective absorption into the bloodstream.It is often combined with other body-building supplements such as mucopolysaccharides complex.

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Local Anesthetic Raw Materials Procaine White Crystalline Powder 59-46-1

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Local Anesthetic Raw Materials Procaine White Crystalline Powder 59-46-1
 
Procaine Basic Info.:
 
Product name: Procaine
Alias: Procaine hydrochloride; Aminocaine; Anadolor; Atoxicocaine;
CAS register number: 59-46-1
Molecular formula: C13H21ClN2O2
Molecular weight: 236.31
Appearance: White crystalline powder
 
Procaine Description:
 
Procaine hydrochloride, also called Novocain, synthetic organic compound used in medicine as a local anesthetic. It became the first and best-known substitute for cocaine in local anesthesia. Generally used in a 1 to 10 percent saline solution, procaine hydrochloride is administered by injection for infiltration (area flooding as in dental anesthesia), nerve-block, spinal, and caudal anesthesia. Unlike cocaine, procaine is not toxic, addicting, or irritating. It has been displaced somewhat by the chemically related drugs lidocaine and mepivacaine, which produce prompter, more intense anesthesia.
 
Procaine HCl is indicated for the production of local or regional analgesia and anesthesia by local infiltration and peripheral nerve block techniques.
 
The routes of administration and concentrations are: for local infiltration use 0.25% to 0.5% (via dilution) and for peripheral nerve blocks use 0.5% (via dilution), 1%, and 2%. (See DOSAGE AND ADMINISTRATION for additional information.)
 
Procaine Usage:
 
Procaine is a kind of local anesthetics. With low toxicity but quick and safe effects, procaine is suitable for local anesthesia, applied to the eye, ear, nose, teeth and other department operation, used for infiltration anesthesia, anesthesia and closed therapy supervisor. Procaine is also used in the production of procaine penicillin.
 

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Local Anesthetics Proparacaine Hydrochloride Proparacaine HCl 5875-06-9

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Local Anesthetics Proparacaine Hydrochloride Proparacaine HCl 5875-06-9 
 
Proparacaine HCL Basic Info.
 
Product Name: Proparacaine hydrochloride 
Synonyms: Proparacaine HCl; Proparacaine Hydrochloride
CAS: 5875-06-9 
Molecular formula: C16H27ClN2O3 
Molecular Weight: 330.85 
EINECS number: 227-541-7 
Related Categories: API 
Use:anesthetic (local),Pharmaceutical raw materials
Packing:Foil bag or as requirments
 
Product Description Of Proparacaine HCL:
 
Anesthesia, local- Proparacaine and tetracaine are indicated to produce local anesthesia of short duration for ophthalmic procedures including measurement of intraocular pressure, removal of foreign bodies and sutures, and conjunctival and corneal scraping in diagnosis and gonioscopy. 
 
Proparacaine HCL Applications: 
 
Proparacaine hydrochloride and tetracaine are also indicated to produce local anesthesia prior to surgical procedures such as cataract extraction and pterygium excision, usually as an adjunct to locally injected anesthetics.Ophthalmic solutions used for intraocular procedures should be preservative-free. Preservatives may cause damage to the corneal epithelium if a significant quantity of solutionenters the eye through the incision.
 

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Lose Stubborn Belly Fat Peptide Anabolic Peptide Cjc-1295 Without Dac 863288-34-0

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Lose Stubborn Belly Fat Peptide Anabolic Peptide Cjc-1295 Without Dac 863288-34-0
 
Basic Information For CJC-1295 Without DAC:
 
Product Name: 
Synonyms: CJC1295; CJC-1295 Acetate; CJC-1295 without DAC; CJC 1295 w/o DAC; MOD GRF 1-29; Neorelin; Modified Sermorelin
CAS: 863288-34-0
MF: C159H258N46O45
MW: 0
Density: 1.45
Molar Mass: 3368.7
Peptide purity: >98.0%
Appearance: White lyophilized powder
Related substance: Total Impurities (%) ≤ 2.0%
Acetate content: ≤ 15.0%
Bacterial Endotoxins: ≤5 IU/mg
Sequence: Tyr-d-ALA-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH2
Source: Chemical Synthesis
Reconstitution: To follow best practice guidelines for reconstituting CJC-1295 without DAC, reconstitute in sterile, bacteriostatic, distilled water, with light sonication if necessary.
Storage for MOD GRF 1-29: Lyophilized MOD GRF 1-29 is stable at room temperature for 90 days, however it should be stored in a freezer below -8°C for any extended period of time. After reconstitution, may be stored for a maximum of 14 days in a refrigerator at 2°C - 8°C. Store vials in an upright position. Store MOD GRF-129 refrigerated between temperatures 2°C - 8°C. Keep in the outer carton in order to protect from light. For one month can be stored at room temperature.
Shelf life: One year from dispatch.
 
What is CJC-1295 without DAC and used for?
 
Modified GRF 1-29 is also known as Mod GRF 1-29, but even more commonly known as CJC-1295 without DAC. It is a protein that is 29 amino acids long and it is a GHRH analogue. CJC-1295 without DAC acts on receptors at the pituitary gland to stimulate the release of Human Growth Hormone.
 
CJC-1295 without DAC could be referred to more properly as a second generation derivative of GHRH. GHRH is modified to create what is known as Releasing Factor (GRF) 1-29, also known as Sermorelin. GRF 1-29 is then further modified to create Mod GRF 1-29 which is CJC-1295 without DAC.
 
Application & More information for CJC-1295 without DAC:
 
Releasing Hormone (GHRH), which is the endogenously secreted GHRH by the arcuate nucleus of the hypothalamus of the human body, is 44 amino acids long. It was discovered, however, that only the first 29 amino acids of the protein were equally as effective in binding to receptors on the pituitary gland as the full 44 amino acid structure. The first 29 amino acids in its protein structure were then isolated, which was then called GRF 1-29, but the problem with this derivative of GHRH was the fact that it was rapidly metabolized and cleared from the body by enzymes. Studies have reported that GRF 1-29's half-life is less than 10 minutes and as little as 5 minutes. This was obviously not enough time to ensure a maximized and sustained release of HGH from the pituitary gland, as studies have demonstrated that the full potential of an HGH pulse from the pituitary requires at least 30 minutes as evidenced by the fact that much higher HGH levels (50 times greater) were observed 15 - 30 minutes into subcutaneous administration of GHRH analogues.
 
Therefore, the solution to this was to modify GRF 1-29 by replacing various amino acids in its structure with other amino acids that would provide a greater resistance to breakdown and cleavage by enzymes. There were many modified analogues developed, and Mod GRF 1-29 (CJC-1295 without DAC) was eventually selected for use, which demonstrated the most promising effects. Mod GRF 1-29 is a modification of GRF 1-29, specifically at amino acids #2, #8, #15, and #27. The result is an extended half-life to that of at least 30 minutes.
 
Mod GRF 1-29 acts upon receptors located in the anterior pituitary gland, and signals the pituitary gland to increase Human  production and cause a release of massive quantities of Human Hormone in a pulsatile manner. The effects of Mod GRF 1-29 are very similar from what would be expected from synthetic HGH administration over the long term, although the amount of time that the released human growth hormone will remain in circulation is of a far less amount of time than synthetic Human Growth Hormone does. Therefore, multiple applications of Mod GRF 1-29 is recommended throughout the day in order to simulate Human Growth Hormone levels that remain high on a constant basis. Mod GRF 1-29 (CJC-1295 without DAC) is commonly combined with a Ghrelin mimetic (also known as a GHRP - Releasing Hexapeptide), such as GHRP-6, GHRP-2, Hexarelin, or Ipamorelin in order to initiate and amplify a greater pulse from the pituitary compared to Mod GRF 1-29 used solitarily on its own.
 

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Lose Weight Fast Fat Burning Steroids Synephrine No Side Effect 94-07-5

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Lose Weight Fast Fat Burning Steroids Synephrine No Side Effect 94-07-5
 
Synephrine Basic Info.
 
Product Name: Synephrine
Synonyms: Oxedrine;Synephrine;AKOS NCG1-0008;AURORA KA-6561
CAS: 94-07-5
MF: C9H13NO2
MW: 167.21
EINECS: 202-300-9
Assay: 99.2%
Appearance: White powder
Package: 25kg/drum
Storage:Keep away from fire and heat source, hermetically deposit, keep in shady, cool and dry condition, protect against the tide.
 
Synephrine Description:
 
Citrus aurantium extract synephrine as standard has been recommended. 4-20mg daily dose of synephrine is as bitter orange extract containing 200-600mg standard products (3-6% synephrine) typical dose.
 
Synephrine Use:
 
Synephrine is lime fruits of the main active ingredient, which can effectively prevent excess energy (heat accumulation), by the wind qi, warm the stomach stimulates the appetite and speeds up metabolism. It is also a mild fragrance expectorant agent, a neurological tranquilizers and laxative treatment of constipation. Users can expect variable effects include consumption of excess calories, reduce appetite and increase satiety, these are likely to lead to weight loss.
 

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Luteinizing Hormone

Luteinizing Hormone is a hormone that is produced by the anterior pituitary gland. It is used to trigger ovulation and development of the corpus luteum.It stimulates Leydig cell production of testosterone and acts synergistically with FSH.It is a heterodimeric glycoprotein.Each monomeric unit is a glycoprotein molecule-one alpha and one beta subunit make the full, functional protein.It is regulated by the gonadotropin-releasing hormone from the hypothalamus.

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