chemical-categories

 

Natural Steroid Hormones Anti Estrogen Steroids Sildenafil Citrate / Viagra 171599-83-2

 

Viagra Basic Info:

 

Product Name: Viagra 

Synonyms: Sildenafil Citrate; Sildenafil; Viagra

CAS number: 139755-83-2

MF: C28H38N6O11S

MW: 666.7

Melting point: 187-189°C

Chemical Properties: White Solid powder

Usage: An orally active selective type 5 cGMP phosphodiesterase inhibitor

Dosage: As with all prescription drugs, proper dosage is at the discretion of a licensed medical doctor. The dose of sildenafil for erectile dysfunction is 25 mg to 100 mg taken not more than once per day between 30 minutes and 4 hours prior to sexual intercourse.

 

Viagra Description:

 

In 16 separate 4-24 week trials of men (over 18 years old) who suffered from impotence for longer than 6 months, dosages between 10-200 mgs were administered. Significant improvements in erectile function, including frequency of penetration as well as erection duration post penetration, were reported with Sildenfil treatment compared to the placebo group.

 

Erections were improved in 72% of the Viagra group verses 18% of the placebo group. In all cases effects were dependant upon dosage and improvement was the greatest when dosage exceeded 100 mgs. Responses were decreased by 40-60% in patients suffering from diabetes and prostatectomy, respectively. Withdrawal rates were less than 5% related to negative side effects and limited response rates.

 

Vardenafil's indications and contra-indications are the same as with other PDE5 inhibitors; it is closely related in function to sildenafil citrate (Viagra) and tadalafil (Cialis). Sildenafil Citrate is solely active in relaxing muscles and increasing blood flow to the heart, lungs and penis due to PDE-5, yet vasodilation is not increased in other parts of the body.

 

Viagra Application:

 

Sildenafil citrate, sold as Viagra, Revatio and under various other trade names, is a drug used to treat erectile dysfunction and pulmonary arterial hypertension (PAH).

 

tadalafil's pharmacologic distinction is its longer half-life (17.50 hours) - compared to sildenafil (4.0-5.0 hours) and vardenafil (4.0-5.0 hours) - resulting in longer duration of action, and so partly responsible for "The Weekend Pill" sobriquet. Furthermore, the longer half-life is the basis for current investigation of tadalafil's daily therapeutic use in relieving pulmonary arterial hypertension. Sildenafil is approved in several world regions as a thrice-daily therapy for pulmonary arterial hypertension.

 

Sildenafil citrate 50 mg is the recommended starting dose for men with erectile dysfunction (ED); however, most men are later titrated to sildenafil 100 mg for improved efficacy.

 

 

99% Female Steroids Hormone Flibanserin For Gaining Women Sexy-Enhancement 167933-07-5

 

Flibanserin Basic Info:

 

Product Name: Flibanserin

Chemical Name: Centrophenoxine HCL

CAS Number: 167933-07-5

EINECS Number: 222-975-3

Molecular Formula: C20H21F3N4O

Molecular Weight: 294.17

Melting Point: 139-143°C

Assay: 99.5%

Appearance: White powder

 

Flibanserin Description:

 

Flibanserin is a novel, non-hormonal drug that has been studied in clinical trials for the treatment of HSDD in premenopausal and postmenopausal women. The application submitted to the FDA is for premenopausal women. Flibanserin is believed to work on key neurotransmitters, or chemicals, in the brain that affect sexual desire. More specifically, it is thought that flibanserin corrects an imbalance of levels of these neurotransmitters by increasing dopamine and norepinephrine (both responsible for sexual excitement) and decreasing serotonin (responsible for sexual inhibition). In clinical studies, flibanserin was evaluated for its ability to increase the frequency of satisfying sexual events, increase the intensity of sexual desire and decrease the associated distress women feel from its loss.

 

Flibanserin Application:

 

Flibanserin is being hailed as "Viagra for women." The experimental drug - designed for post-menopausal women with low sex drives - has now won approval from an advisory panel for the Food and Drug Administration (FDA).

 

Flibanserin is an antidepressant that failed to help depression in clinical trials, but was noted to have improved sexual health outcomes. It's not uncommon for a drug to be developed for one purpose, then approved for another. Sildenafil (Viagra) was originally developed to lower blood pressure, but failed those trials. The benefit of both of these drugs was discovered by accident. However, flibanserin has now been studied for its effects on sexual health for nearly a decade.

 

Flibanserin doesn't have any interactions with hormonal medications, Thorp says. It does seem to interact with the original libido helper, though: some panelists recommended a warning against drinking alcohol while taking it, Reuters reported. (Interested in natural alternatives to hormone replacement therapy? The Natural Menopause Solution has everything you need to tame symptoms and trigger rapid, healthy weight loss in menopausal women.)

 

HSDD is the most commonly reported form of female sexual dysfunction. HSDD is defined as a persistent or recurrent deficiency or absence of sexual fantasies and desire for sexual activity that causes marked distress or interpersonal difficulty, and which is not better accounted for by a medical, substance-related, psychiatric (e.g., depression) or other sexual condition. The cause of HSDD is believed to involve a multitude of social, psychological and biological factors and may be attributed to

a complex interplay of these factors.

 

Flibanserin Function:

 

A new drug designed to boost sexual desire in women is controversial for some and eagerly awaited by others, but it's hit a potentially serious snag. The drug didn't boost women's desire any more than a placebo in two clinical trials. The Food and Drug Administration posted the clinical trial results on its website today in advance of a committee meeting on Friday, when a panel of experts will vote whether or not to recommend approval of the drug called flibanserin.(The FDA usually follows the recommendations of its expert panels.) Although there was a slight increase in the number of sexually satisfying events flibanserin users had each month, the FDA staff who reviewed the results said the so-called response rate isn't "particularly compelling."

 

 

99% Pure Anabolic Androgenic Steroids Raw 4-DHEA / 4DHEA For Muscle Building 571-44-8 

 

4-DHEA Basic Info.

 

Product Name: 4-DHEA

Alias: 4-DHEA, 4-AD, 4-Dehydroepiandrosterone, 4 androstene-3b-ol, 17-one

CAS: 571-44-8 

MF: C19H28O2

MW: 288.42442

Purity: 99%

Appearance: White Crystalline Powder

Place of Origin: China

Standard: USP

Certification: SGS

Method of Analysis: HPLC

 

4-DHEA Description:

 

4-DHEA is a naturally occurring DHEA isomer. It's structure closely resembles regular DHEA but the double bond in the 4th position dramatically changes its effects.

 

4-DHEA readily converts to 4-androstenediol, rather than 5-androstenediol, boosting its anabolic potency more than 2x over regular DHEA. (6-8, 11) 4-DHEA is also expected to have a higher conversion rate to test compared to regular DHEA. (6, 7) The 4-DHEA also lacks the calorie burning thermogenic properties, therefore offering superior calorie retention for a bulking effect. (4) This increased anabolic potency and reduced thermogenic action will lead to noticeable gains in strength, lean tissue growth, and weight gain.

 

4-DHEA will have mild estrogen conversion that can be easily balanced with a non-aromatizing steroid like androsterone or 1-DHEA. Overall gains will be similar to the original "4-AD" banned in the 2004 Steroid Control Act.

 

As with the other DHEA isomers, 4-DHEA is naturally occurring and non-toxic. (9) Side-effects such as oily skin or reduced fertility are considered mild and temporary. The most notable side-effect would be suppression of natural test production, which makes post cycle therapy necessary after a cycle. Overall 4-DHEA is a very safe and effective lean muscle building agent.

 

The only downfall to 4-DHEA is its high cost due to the high dose that is required to see significant muscle building effects.

 

4-DHEA Applications:

 

4-DHEA is a naturally occurring non-methylated (non-17AA) PRO-steroid. Although 4-DHEA can aromatize to estrogen it is probably not enough to cause high estrogen related side-effects.

 

Overall results will be similar to or the original 4-AD banned back in 2004. Higher doses of this compound will produce fairly lean gains in muscle mass, with moderate improvements in strength. This product may produce some bloat from the estrogen conversion, which could be countered by administering an aromatase inhibitor, but this will largely defeat the purpose of using this compound to begin with.

 

Since this compound is naturally occurring and non-methylated overall side-effects will be fairly mild. However, high doses may also lead to oily skin, acne and increased blood pressure. Because this steroid is non-17AA there should be less concern about it negatively affecting the HDL/LDL ratio.

 

Because this compound can convert to testosterone it can also convert to DHT and other 5A-reduced metabolites. This can serve as a good stack with progestational or relatively non-androgenic compounds that may create problems with libido or gyno because of lacking androgenic potency.

 

 

Anti-Estrogens Nolvadex Steroids Powder Tamoxifen Citrate For Breast Cancer 54965-24-1

 

Tamoxifen Citrate Basic Info.:

 

Product Name: Tamoxifen Citrate

Product name: Tamoxifen Citrate

Synonym: Nolvadex

CAS Registry Number: 54965-24-1

Molecular Formula: C32H37NO8

Molecular Weight: 563.64

Assay: 99%

Packing: 1kg/bag

Appearance: White crystalline powder

 

Tamoxifen Citrate Description:

 

1.This product is most often referred to as "Nolvadex" by bodybuilders. Nolvadex is not a steroid, rather a selective estrogen blocker. While Nolvadex doesn't prevent the buildup of estrogen in the body, it does prevent it from acting on certain receptors, most notably, those located in the nipples. This has obvious benefits to bodybuilders, because this is the area in which "gyno" occurs during the use of aromatizing steroids such as testosterones.

 

2.Nolvadex (tamoxifen citrate) is very comparable to Clomid, behaves in the same manner in all tissues, and is a mixed estrogen agonist/antagonist of the same type as Clomid. The two molecules are also very similar in structure. It is not correct that Nolvadex reduces levels of estrogen: rather, it blocks estrogen from estrogen receptors and, in those tissues where it is an antagonist, causes the receptor to do nothing.

 

The belief that it reduces gains seems to stem from the fact that the scientific literature reports a slight reduction in IGF-1 (individuals using anabolic steroids were not studied though) from use of Nolvadex.

 

Thus, Dan Duchaine reported that it reduces IGF-1 and therefore reduces gains. However, if this effect exists at all,

it must be very minor, due to the excellent gains that many have made, and from the fact that no one has noticed any such thing from Clomid, which has the same activity profile.

 

The fact that Nolvadex will reduce water retention may result in the user agreeing that gains are less, since weight gain is less, thus reinforcing the bias.

 

Tamoxifen Citrate Applications:

 

Commonly known as Nolvadex or Nolva, Tamoxifen Citrate generally serves two purposes for the anabolic steroid user .Tamoxifen Citrate is one of the most commonly used medications among performance enhancers but more often than not it is used for remedy rather than solution.

 

For on cycle side-effect prevention and more commonly for post cycle therapy (PCT) needs. Regardless of the purpose at hand Nolva is generally very well-tolerated by those who use it and this includes both men and women. Women will use it at a much lower dose and many women who supplement with Nolvadex will do so for more of an actual solution rather than remedy.

 

Beyond on cycle use the most common time in-which Tamoxifen Citrate is used by performance enhancers is during the PCT period; after anabolic steroid use is complete. Nolva has been shown to greatly increase testosteronse stimulation in part by largely increasing Luteinizing release.

 

Tamoxifen Citrate is also used in medical practice to combat breast cancer.

 

 

High Purity Nootropic Powder Picamilon / Pikamilone For Cognition Enhancer 34562-97-5 

 

Pikamilone Basic Info.:

 

Product Name: Pikamilone

Synonyms: Pikamilone Hydrochloride;Nicotinoyl-Gaba;N-(3-Carboxypropyl) Nicotinamide;4-[(Pyridin-3-Ylcarbonyl)Amino]Butanoic Acid;4-(Nicotinamido)Butanoic Acid;Pikamiline;Pikamilone;

CAS: 34562-97-5

MF: C10H12N2O3

MW: 208.21

EINECS: N/A

Density: 1.245

Product Categories: Pharmaceutical Intermediates; Nootropic Drug; Heterocycles; Chemistry; API; Other APIs

Usage: anti-cancer agent; Used as a smart improve medicine

 

Picamilon Description:

What is the best way to use Picamilon powder and what Picamilon dosage should you be taking for optimal effects? This nootropic combination of GABA and Niacin offers a lot of cognitive benefits and mood enhancing effects. However, as an anxiolytic, it is often overlooked in favor of other nootropics like 

Sulbutiamine and Theanine. Picamilon is one of several Nootropic supplements that were originally developed in Russia (then called the Soviet Union) during the Cold War. This is probably why the supplement has been incredibly underused in the West for many years. Most of the studies and research were conducted and written in Russian, preventing its widespread dissemination even though Picamilon has been used since the early 1970′s. As such, it can be difficult to find usage and dosage information for this supplement online. In this article, we will tell you how to use Picamilon and what the recommended daily dose is. 

 

Picamilon Benefits:

The primary Nootropic benefits of this supplement center on mood boosting and overall brain function improvements. This includes helping to reduce feelings of stress and anxiety. In fact, many users feel that this supplement is so good at reducing these feelings that they use it on a regular basis to help relax. An improved positive outlook and attitude will also often follow. Once a person is relaxed, they will usually find themselves having improved sleep which is also more restful and deeper. As a brain booster, Picamilon benefits also include better mental energy and improved clarity and focus. It is easier to think and make decisions as well when using Picamilon supplements

 

Picamilon Function:

Picamilon is able to cross the blood-brain barrier and then is hydrolyzed into GABA and niacin. The released GABA in theory would activate GABA receptors potentially producing an anxiolytic response. The second released component, niacin acts as a strongvasodilator, which might be useful for the treatment of migraine headaches 

 

Picamilon Dosage:

The standard dosage range for Picamilon is between 50 and 300 mg per day.Of course, this may be split into several different administrations throughout the day, depending upon how it effects the user. Generally, a divided dose means one in the morning and one in the evening. Most supplements sell it in 150 mg tablets or capsules, but you can also buy it as a bulk powder to get more control over your dosages. Picamilon works best when taken on an empty stomach and the effects of this nootropic will last anywhere from two to four hours. You should always start out with the smallest effective Picamilon dose possible. Study the benefits obtained and then determine if increasing the dose is in order.

 

Stacking & Cycling Picamilon:

Many users have found that stacking and cycling their Picamilon dosages can be very effective. It is certainly very safe and it may even help to increase the effects of other Nootropic supplements like the Racetams including Aniracetam and Piracetam. There are a number of other Nootropics that have similar effects to Picamilon, but might lead to tolerance if used on a daily basis. This means that it might be helpful to include Picamilon as part of a cycle with something like, say, 

Start with the safer option (Picamilon) and use on a 3 or 4 day on and 2 day off cycle. For the days off of Picamilon, substitute with the 

 

 

Jin Yang Base Pharmaceutical Raw Materials For Treatment Sexual Disorder Jinyang Base 

 

Jin Yang Base Basic Info:

 

Product Name: Jin Yang Base

Synonyms: Jin Yang Base;Sildenafil Citrate Tablets;Jinyangjian;Jinyang Alkali;Jinyang Base

Assay: 99.5%

Packing: 1kg/foil bag

Appearance: Light yellow crystalline powder.

Solubility: slightly soluble in water and slightly soluble in ethanol, soluble in lipids, odorless.

Usage: Sexual function decline; Non-organic sexual disorder, ED patients

 

Jin Yang Base Description:

 

This ingredients belongs to phosphodiesterase type 5 of this kind of inhibitor. When sexuelle erregung, neurone of NANC and nitrogen oxide in endothelial cells synthase and catalyse L-arginine to synthetize nitrogen oxide, which activate guanosine to synthesis increase, then lead cavernous body of penis smooth muscle and artery of penis into relaxation, blood into penis sponge sinus, make penis erect.

 

Jin Yang Base Application:

 

For the treatment of erectile dysfunction (ED), the use of antidepressants, antipsychotics and anti-hypertensive drugs cause impotence, and after surgery or trauma caused by impotence are valid

 

 

Anabolic Androgenic Steroid Hormone Trestolone Acetate For Male Contraception 6157-87-5

 

Trestolone Acetate Basic Info.

 

Product Name: Trestolone Acetate

Synonyms: 17β-Hydroxy-7α-methylestr-4-en-3-one acetate;3-Oxo-7α-methylestra-4-ene-17β-ol acetate;Acetic acid 3-oxo-7α-methylestra-4-ene-17β-yl ester;NSC-69948;U-15614

CAS No.: 6157-87-5

Molecular Formula: C21H30O3

Molecular Weight: 330.47

Melting Point: 447.571 °C at 760 mmHg

Flash Point: 194.228 °

Density: 1.117 g/cm3

Appearance: White powder

Usage: Pharmaceutical raw materials, bodybuilding and sex enhancement

 

Trestolone Acetate Description:

 

Chemically speaking, trestolone acetate(MENT) actually an alright looking drug. It doesn’t show much interaction with Sex Hormone Binding Globulin, which means that a good portion ought to stay unbound and active in the blood. Also, the drug is a potent binder to the androgen receptor, while showing minimal affinity for the progesterone and mineralocorticoid receptors respectively. Since it is not able to be 5a-reduced into a dihydro-version, it likely wouldn’t cause many of the side effects commonly associated with Dihydrotestosterone. This is also a likely reason that it is less apt to cause prostate enlargement, and may even be indicated for the treatment of specific prostate issues.

 

The ability of 7 alpha-methyl-19-nortestosterone acetate (MENT) to increase the weights of ventral prostate and seminal vesicles of castrated rats was four times higher than that of testosterone, while its effect on the weights of bulbocavernosus plus levator ani muscles (muscle), was 10 times that of testosterone.

 

Various forms of MENT in human pharmaceutical preparations and devices for contraception and hormone therapy, specifically MENT Ac implant and MENT transdermal gel and patch formulations, are currently under clinical investigation. MENT is absorbed transdermally up to three times the rate of testosterone - 17 methyl testosterone and 17-α methyl testosterone.

 

MENT will have application in a wide range of indications beyond androgen replacement therapy and contraception, including, without limitation, primary hypogonadism, testicular failure, ASIH, baldness, sarcopenia, loss of bone mass, muscle wasting and cachexia, BPH, prostate cancer and of course, bodybuilding and sports performance enhancement. Trestolone acetate is the chemical name of active ingredient in MENT. MENT is a registered trademark of Population Council, Inc. in the United States and/or other countries.

 

Trestolone Acetate Application:

 

MENT, as a transdermal and/or intramuscular preparation, will have application in a wide range of indications beyond androgen replacement therapy and contraception, including, without limitation, primary hypogonadism, testicular failure, ASIH, baldness, sarcopenia, loss of bone mass, muscle wasting and cachexia, BPH, prostate cancer and of course, bodybuilding and sports performance enhancement.

 

 

Anabolic Supplements Raw Steroid Powders Letrozole Femara For Breast Cancer 112809-51-5

 

Letrozole Basic Info.:

 

Product Name: Letrozole (Letrozol-e)

Alias: Letrazol-e; Letrozol-e Femara

CAS No: 112809-51-5

Molecular formula: C17H11N5

Molecular weight: 285.3

Appearance: White power

Assay: 99%

Delivery time: 5-7 days 

Minimum order: 10g

Supply ability: 500kg/month

Quality standard: USP32   

Payment:Western Union and Money Gram

Delivery:Within 24hours After Your Payment

 

Letrozole Descriptions:

 

This medication is used to treat certain types of breast cancer (such as hormone-receptor-positive breast cancer) in women after menopause. Letrozole is also used to help prevent the cancer from returning. Some breast cancers are made to grow faster by a natural hormone called estrogen. Letrozole decreases the amount of estrogen the body makes and helps to slow or reverse the growth of these breast cancers.

 

OTHER USES: This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.

This medication may also be used to treat infertility in women.

 

Letrozole Application:

 

Femara is a non-steroidal aromatase inhibitor (lowers estrogen production) used to treat breast cancer in postmenopausal women. It is often given to women who have been taking tamoxifen (Nolvadex, Soltamox) for 5 years. Femara is available in generic form. Common side effects of Femara include hot flashes, hair loss, joint/bone/muscle pain, tiredness, unusual sweating or night sweats, nausea, diarrhea, dizziness, trouble sleeping, drowsiness, weight gain, weakness, flushing (warmth, redness, or tingly feeling), headache, constipation, numbness/tingling/weakness/stiffness in your hand or fingers, or pain in your hand that spreads to your arm, wrist, forearm, or shoulder.

 

 

Pharmaceutical Grade Treatment Of Prostate Cancer Peptide Deslorelin Acetate 57773-65-6

 

Deslorelin Basic Info.:

 

Product Name: Deslorelin

Specification: 50mg*50vials/kit

Synonyms: GLP-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-NHET;Desorelin;Deslorelin; Deslorelin Acetate; Deslorelin (Human);

CAS: 57773-65-6

MF: C64H83N17O12

MW: 1282.45

Purity: 98%

Storage temp.: −20°C

Product Categories: Peptide;Hormones

Usage: Biochemical research;Clinical used in the treatment of prostate cancer.

 

Deslorelin Description:

 

Deslorelin acetate is an injectable gonadotropin releasing hormone super-agonist (GnRH agonist) also known as an LHRH agonist. It stops the production of sex hormones (and oestrogen). Deslorelin Acetate is marketed by Peptech with the brand name Ovuplant. It is currently approved for use in veterinary medicine and is used to induce ovulation in mares as part of the artificial insemination process. It is also used to stabilize high-risk pregnancies, mainly of livestock. Unlike other GnRH agonists, which are mainly used to inhibit uteinizing hormone and follicle-stimulating hormone by their ultimate downregulation of the pituitary gland, Deslorelin is primarily used for the initial flare effect upon the pituitary, and its associated surge of LH secretion.

 

Deslorelin Application:

 

Deslorelin was successfully trialed in the US and was approved for veterinary use under certain  circumstances. In Europe, it was approved for use in equine assisted reproduction. It is also being trialed in humans to study its efficacy in treatment of breast cancer in women,and in treating  precocious puberty and congenital adrenal hyperplasia in male and female children.

 

 

Pharmaceutical Raw Materials Natural Steroid Hormones Powder Methyldienedione 5173-46-6

 

Methyldienedione Basic Info.:

 

Product Name: Methyldienedione

Alias: Estra-4,9-diene-3,17-dione

CAS register number: 5173-46-6

Molecular Formula: C18H22O2

Molecular Weight: 270.37

Melting Point: 131-134°C

Assay: 98%min

Grade: Pharmaceutical Grade

Storage: Shading, confined preservation

Packing: 1kg/foil bag. 25kg/drum

Character: White crystalline powder.

Usage: A potential metabolitie of STS 557 (Dienogest). A steroid with antiglucocorticoid activity.

 

Methyldienedione Description:

 

Estra-4,9-diene-3,17-dione is a powerful pro-steroid chemically similar to the anabolic agent Trenbolone.

When in the body, estra-4,9-diene-3,17-dione completes the conversion to Trenbolone. Trenbolone is a potent anabolic steroid, which binds to specific receptors present in reproductive tissue, muscle and fat.

 

Estra Diene Dione (estra-4,9-diene-3,17-dione) is an anabolic steroid and a precursor to Estra Diene Dione. It became a controlled substance in the US on January 4, 2010, and is classified as a Schedule III anabolic steroid under the United States Controlled Substances Act. Previous to this, it was sold as a bodybuilding supplement within the United States, and often mistakenly marketed as a prohormone for trenbolone, a veterinary steroid. Prior to its scheduling, it was part of a number of supplements that were seized during FDA enforcement for selling unapproved new drugs. The actual target steroid, Estra Diene Dione has some structural similarity to trenbolone, but lacks the 11-carbon -ene bond.

 

Methyldienedione Applications:

 

1. Protection from gynomastia,

2. Increased sex drive/libido,

3. Enhanced intensity & focus,

4. Estrogen control,

5. Positive effects on strength & lean mass.