Immunomodulators induces, enhances immune system suppressor, prevents organ rejection


Inhibitor Library >98%

The inhibitors library contains over 2672 active compounds, variety structure. Most products have been reported with clear biological and pharmacological activity, which can be used in not only specific research but also high-throughput screening and high-content screening.

Properties Suppliers

CODE LUM CAS # 521-31-3 NAME LUMINOL MOL FORM. C8H7N3O2 MOL WT. 177.16 Chemiluminescent material used for analytical purposes and chemistry demonstrations . Luminol is a cyclic diacyl hydrazide that exhibits chemiluminescence upon oxidation. Luminol can also be oxidized, and chemiluminesce, by compounds containing iron, copper,GOLD, and cyanide. The excitation/emission maxima for luminol are 355/411 nm.

Properties Suppliers
Nicotinamide Adenine Dinucleotide, Disodium Salt LAB GRADE 95%

NADH, Disodium Salt functions as a coenzyme of a large number of oxidoreductases.

NADH is the reduced form of nicotinamide adenine dinucleotide (NAD) that can donate electrons as part of a reducing reaction. In that process, NADH becomes oxidized to produce beta-NAD. A variety of enzymes use NADH plus Hydrogen ion to reduce substrates, generating beta-NAD as well as the reduced product. For example, NADH:ubiquinone oxidoreductase accepts two electrons from NADH and passes them to ubiquinone (coenzyme Q) as part of the mitochondrial electron transport chain.

NADH is a coenzyme that functions as a regenerating electron donor in catabolic processes including glycolysis, beta-oxidation and the citric acid cycle. As a reagent, NADH can be used in enzyme cycling assays to amplify detection of activity of biologically relevant enzymes or metabolites present in low concentrations.

β-Nicotinamide adenine dinucleotide (NAD) and β-Nicotinamide adenine dinucleotide, reduced (NADH) comprise a coenzyme redox pair (NAD:NADH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. In addition to its redox function, NAD/NADH is a donor of ADP-ribose units in ADP-ribosylaton (ADP-ribosyltransferases; poly(ADP-ribose) polymerases ) reactions and a precursor of cyclic ADP-ribose (ADP-ribosyl cyclases).
As a reagent, NADH can be used in enzyme cycling assays to amplify detection of activity of biologically relevant enzymes or metabolites present in low concentrations.

Molecular Formula: C21H29N7O14P2 • 2Na
Formula Weight: 711.4

Properties Suppliers

Streptozocin is a naturally occurring chemical that is particularly toxic to the insulin-producing beta cells of the pancreas in mammals. It is used in medicine for treating certain cancers of the Islets of Langerhans and used in medical research to produce an animal model for Type 1 diabetes.It is an antibiotic that is produced by Stretomyces achromogenes.It is known to inhibit DNA synthesis, interfere with biochemical reactions of NAD and NADH, and inhibit some enzymes involved in gluconeogenesis. Its activity appears to occur as a result of formation of methylcarbonium ions, which alkylate or bind with many intracellular molecular structures including nucleic acids. Its cytotoxic action is probably due to cross-linking of strands of DNA, resulting in inhibition of DNA synthesis.

Properties Suppliers

Vindesine is an anti-mitotic vinca alkaloid used in chemotherapy. It is used to treat many different types of cancer, including leukaemia, lymphoma, melanoma, breast cancer, and lung cancer.Vindesine is indicated for the treatment of acute lymphocytic leukemia of childhood that is resistant to vincristine and non-oat cell lung cancer.Vindesine acts by causing the arrest of cells in metaphase mitosis through its inhibition tubulin mitotic funcitoning. The drug is cell-cycle specific for the S phase.

Properties Suppliers
tacrolimus fk-506 pharmaceutical intermediates organ transplant 104987-11-3 USP 102%



Molecular Formula


Molecular Weight


CAS Registry Number


A white or almost white powder

Specific rotation:-82°~ -90°


Residue on ignition≤0.2%

Heavy metals≤20 ppm

Related substances

Impurity A (Ascomycin) ≤0.5%

Impurity B(Dihydro tacrolimus)≤0.5%

Any individual unknown impurity ≤0.1 %

Total impurities ≤1.0%

Tautomers I+II≤1.0%

Assay:98.0% ~ 102.0%


An immunosuppressant that blocks T cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2. Shown to inhibit the activity of FK-506 binding protein, thereby reversing its effects on sarcoplasmic reticulum Ca+2 release.

For use after allogenic organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection. It was first approved by the FDA in 1994 for use in liver transplantation, this has been extended to include kidney, heart.

Properties Suppliers