Musculoskeletal drugs usd in treating musculoskeletal disorders, muscle pain, tendons, joints

chemical-categories

Flurbiprofen

Flurbiprofen is a member of the phenylalkanoic acid derivative family of non-steroidal anti-inflammatory drugs (NSAIDs) used to treat the inflammation and pain of arthritis.Flurbiprofen tablets are indicated for the acute or long-term symptomatic treatment of rheumatoid arthritis, osteorarthritis and anklosing spondylitis. It may also be used to treat pain associated with dysmenorrhea and mild to moderate pain accompanied by inflammation.It is structually and pharmacologically related to fenoprofen, ibuprofen, and ketoprofen, and has similar pharmacological actions to other prototypica NSAIAs. Flurbiprofen exhibits antiinflammatory, analgesic, and antipyretic activities.

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Gallamine Triethiodide

Gallamine Triethiodide is a non-depolarising muscle relaxant. It acts by combining with the cholinergic receptor sites in muscle and competitively blocking the transmitter action of acetylcholine.Gallamine triethiodide has a parasympatholytic effect on the cardiac vagus nerve which causes tachycardia and occasionally hypertension.It is commonly used to stabilize muscle contractions during surgical procedures.

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Ibuprofen

Ibuprofen is a nonsteroidal anti-inflammatory drug used for relief of symptoms of arthritis, fever, as an analgesic for pain, especially where there is an inflammatory component, and dysmenorrhea. It is known to have an antiplatelet effect, though it is relatively mild and short-lived when compared with aspirin or other better-known antiplatelet drugs.Ibuprofen also acts as a vasodilator, having been shown to dilate coronary arteries and some other blood vessels.

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Ketoprofen

Ketoprofen is a is one of the propionic acid class of non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic effects.It acts by inhibiting the body's production of prostaglandin.Ketoprofen can also be used for treatment of some pain, especially nerve pain like sciatica, post-herpetic neuralgia and referred pain for radiculopathy, in the form of a cream, ointment, liquid, spray, or gel which also contains ketamine and lidocaine, along with other agents which may be useful such as cyclobenzaprine, amitryptiline, acyclovir, gabapentin, orphenadrine and other drugs used as NSAIDs or adjuvant, atypical or potentiators for pain treatment.

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Ketorolac

Ketorolac is a non-steroidal anti-inflammatory drug in the family of heterocyclic acetic acid derivative, often used as an analgesic. Ketorolac acts by inhibiting the bodily synthesis of prostaglandins. Ketorolac in its oral (tablet or capsule) and intramuscular (injected) preparations is a racemic mixture of both (S)-(-)-ketorolac, the active isomer, and (R)-(+)-ketorolac.Ketorolac is used to treat osteoarthritis and control acute pain, including pain after surgery. It should not be used for more than 5 days.

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Meclofenamate Sodium

Meclofenamate Sodium is a nonsteroidal anti-inflammatory drug (NSAID) used to treat minor aches and pains associated with the common cold, headache, muscle aches, backache, and arthritis. It may also be used to reduce fever. Meclofenamate Sodium works by blocking the enzyme in your body that makes prostaglandins. Decreasing prostaglandins helps to reduce pain, swelling, and fever.

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Meclofenamic Acid

Meclofenamic acid is a non-steroidal anti-inflammatory agent with antipyretic and antigranulation activities. It also inhibits prostaglandin biosynthesis. It is used for the relief of mild to moderate pain, for the treatment of primary dysmenorrhea and for the treatment of idiopathic heavy menstrual blood loss, relief of the signs and symptoms of acute and chronic rheumatoid arthritis and osteoarthritis. Meclofenamic acid has the advantage of good activity against bacterial pathogens important to poultry.

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Mefenamic Acid

Mefenamic acid is an anthranilic acid derivative, is a member of the fenamate group of non-steroidal anti-inflammatory drug.It is used to treat pain, including menstrual pain. It is typically prescribed for oral administration.It decreases inflammation (swelling) and uterine contractions.Mefenamic acid synthesized from 2-chlorobenzoic acid and 2,3-dimethylaniline.

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Meloxicam

Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID) with analgesic and fever reducer effects. It is a derivative of oxicam, closely related to piroxicam, and falls in the enolic acid group of NSAIDs.It was developed by Boehringer-Ingelheim. It inhibits cyclooxygenase (COX), the enzyme responsible for converting arachidonic acid into prostaglandin H2-the first step in the synthesis of prostaglandins, which are mediators of inflammation and leads to a decrease of the synthesis of prostaglandins, therefore, inflammation is reduced.

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Methocarbamol

Methocarbamol is a central muscle relaxant used to treat skeletal muscle spasms. It is the carbamate of guaifenesin, but does not produce guaifenesin as a metabolite.It is use as an adjunct to rest, physical therapy, and other measures for the relief of discomforts associated with acute, painful musculoskeletal conditions. It is structurally related to guaifenesin. Methocarbamol's exact mechanism of causing skeletal muscle relaxation is unknown. It is thought to work centrally, perhaps by general depressant effects. It has no direct relaxant effects on striated muscle, nerve fibers, or the motor endplate. It will not directly relax contracted skeletal muscles.

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