Ophthalmology Drugs used in eye diseases treatment

chemical-categories

Chlorhexidine

Chlorhexidine is a chemical antiseptic. It is effective on both Gram-positive and Gram-negative bacteria, although it is less effective with some Gram-negative bacteria. It has both bactericidal and bacteriostatic mechanisms of action. It is also useful against fungi and enveloped viruses, though this has not been extensively investigated. For use in animals, it is used as a topical disinfectant of wounds. It is commonly used to manage skin infections in dogs. It is harmful in high concentrations, but is used safely in low concentrations in many products, such as mouthwash and contact lens solutions.

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Ciprofloxacin

Ciprofloxacin is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class. It is a second-generation fluoroquinolone antibacterial. It kills bacteria by interfering with the enzymes that cause DNA to rewind after being copied, which stops synthesis of DNA and of protein.Ciprofloxacin is used to treat a infections of bones and joints, endocarditis, gastroenteritis, malignant otitis externa, respiratory tract infections, cellulitis, urinary tract infections, prostatitis, anthrax, chancroid.Ciprofloxacin can alter and be altered by the metabolism and effects of other drugs, resulting in some significant drug-drug interactions that may affect the musculoskeletal, central nervous, renal, and other systems.

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Dexamethasone

Dexamethasone is a potent synthetic member of the glucocorticoid class of steroid drugs.It is a glucocorticoid anti-inflammatory agent.It regulates T cell survival, growth, and differentiation and Inhibits the induction of nitric oxide synthase.It acts as an anti-inflammatory and immunosuppressant.It is also used to treat difficult ear infections, especially in dogs. It can also be combined with trichlormethiazide to treat horses with swelling of distal limbs and general bruising.Dexamethasone is used in transvenous screw-in cardiac pacing leads to minimize the inflammatory response of the myocardium,used as a direct chemotherapeutic agent in certain hematological malignancies, especially in the treatment of multiple myeloma.

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Dexamethasone Sodium Phosphate

Dexamethasone Sodium Phosphate is a systemic corticosteroid. It induces apoptosis and inhibits sodium phosphate symporter. It is used in the treatment of emetic effects of cancer therapy and epicondylitis, to treat eye inflammation caused by infections, injury, surgery, or other conditions. Dexamethasone Sodium Phosphate suppresses the inflammatory response to a variety of agents and it probably delays or slows healing.

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Gentamicin

Gentamicin is an aminoglycoside antibiotic, used to treat many types of bacterial infections, particularly those caused by Gram-negative organisms.It is synthesized by Micromonospora, a genus of Gram-positive bacteria widely present in the environment (water and soil).Gentamicin is one of the few heat-stable antibiotics that remain active even after autoclaving, which makes it particularly useful in the preparation of some microbiological growth media. It is used during orthopaedic surgery when high temperatures are required for the setting of cements.

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Neomycin

Neomycin is produced by Streptomyces fradiae.It is an aminoglycoside antibiotic.It is used to treatment for superficial eye infections caused by susceptible bacteria (used in combination with other antiinfectives), treatment of otitis externa caused by susceptible bacteria, treatment or prevention of bacterial infections in skin lesions, and use as a continuous short-term irrigant or rinse to prevent bacteriuria and gram negative rod bacteremia in abacteriuric patients with indwelling catheters.

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Olopatadine Hydrochloride

Olopatadine Hydrochloride is an antihistamine as well as anticholinergic and mast cell stabilizer. It is used to treat itching associated with allergic conjunctivitis.

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Rupatadine Fumarate

Rupatadine Fumarate is H1 and PAF antagonist used primarily in treatment of allergic rhinitis symptoms, seasonal or perennial.

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Tetracycline

Tetracycline is a broad spectrum polyketide antibiotic produced by the Streptomyces genus of Actinobacteria. It exerts a bacteriostatic effect on bacteria by binding reversible to the bacterial 30S ribosomal subunit and blocking incoming aminoacyl tRNA from binding to the ribosome acceptor site. It also binds to some extent to the bacterial 50S ribosomal subunit and may alter the cytoplasmic membrane causing intracellular components to leak from bacterial cells.It is used to treat bacterial infections such as Rocky Mountain spotted fever, typhus fever, tick fevers, Q fever, rickettsialpox and Brill-Zinsser disease,infections caused by Chlamydiae spp., B. burgdorferi (Lyme disease), and upper respiratory infections caused by typical (S. pneumoniae, H. influenzae, and M. catarrhalis) and atypical organisms (C. pneumoniae, M. pneumoniae, L. pneumophila),acne.

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latanoprost USP 99%

Name

Latanoprost

Synonyms

Propan-2-yl 7-[3,5-dihydroxy-2-(3-hydroxy-5-phenyl-pentyl)-cyclopentyl]hept-5-enoate

Molecular Formula

C26H40O5

Molecular Weight

432.60

CAS Registry Number

130209-82-4

 

Pale yellow to colorless Oil

Specific Rotation:+32°~ +38°

Water≤0.5%

Purity by HPLC> 99.0%

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