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Chymotrypsin is a digestive enzyme component of pancreatic juice acting in the duodenum where it performs proteolysis, the breakdown of proteins and polypeptides. Chymotrypsin preferentially cleaves peptide amide bonds where the carboxyl side of the amide bond (the P1 position) is a large hydrophobic amino acid (tyrosine, tryptophan, and phenylalanine). These amino acids contain an aromatic ring in their sidechain that fits into a 'hydrophobic pocket' (the S1 position) of the enzyme. It is activated in the presence of trypsin.http://www.creative-enzymes.com/product/Native-Chymotrypsin_823.html
Arginase (EC 3.5.3.1, arginine amidinase, canavanase, L-arginase, arginine transamidinase) is a manganese-containing enzyme. The reaction catalyzed by this enzyme is:arginine + H2O → ornithine + urea. It is the final enzyme of the urea cycle. It is ubiquitous to all domains of life.http://www.creative-enzymes.com/product/Native-Rat-Arginase_1520.html
Nilotinib (AMN-107) can inhibit Bcr-Abl with IC50 of 30 nM. More information please visit the website: http://www.creative-enzymes.com/product/Nilotinib-AMN107-_2224.html
Bafetinib (INNO-406) More information please visit the website: http://www.creative-enzymes.com/product/Bafetinib-INNO406-_2229.html
Docetaxel (Taxotere) can inhibit microtubule disassembly with IC50 of a range of 0.31-100 nM. More information please visit the website: http://www.creative-enzymes.com/product/Docetaxel-Taxotere-_2231.html
PCI-32765(Ibrutinib) can inhibit bruton tyrosine kinase (Btk) with IC50 of 0.46 nM. More information please visit the website: http://www.creative-enzymes.com/product/PCI32765-Ibrutinib-_2227.html
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