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Native Chymotrypsin LAB GRADE 98%

Chymotrypsin is a digestive enzyme component of pancreatic juice acting in the duodenum where it performs proteolysis, the breakdown of proteins and polypeptides. Chymotrypsin preferentially cleaves peptide amide bonds where the carboxyl side of the amide bond (the P1 position) is a large hydrophobic amino acid (tyrosine, tryptophan, and phenylalanine). These amino acids contain an aromatic ring in their sidechain that fits into a 'hydrophobic pocket' (the S1 position) of the enzyme. It is activated in the presence of trypsin.http://www.creative-enzymes.com/product/Native-Chymotrypsin_823.html

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Native Human Urokinase LAB GRADE

Urokinase is a serine protease (EC 3.4.21.73). Urokinase was originally isolated from human urine, but is present in several physiological locations, such as blood stream and the extracellular matrix. The primary physiological substrate is plasminogen, which is an inactive form (zymogen) of the serine protease plasmin. Activation of plasmin triggers a proteolysis cascade that, depending on the physiological environment, participates in thrombolysis or extracellular matrix degradation. This links urokinase to vascular diseases and cancer.http://www.creative-enzymes.com/product/Native-Human-Urokinase_856.html
 

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Native Rat Arginase LAB GRADE 97%

Arginase (EC 3.5.3.1, arginine amidinase, canavanase, L-arginase, arginine transamidinase) is a manganese-containing enzyme. The reaction catalyzed by this enzyme is:arginine + H2O → ornithine + urea. It is the final enzyme of the urea cycle. It is ubiquitous to all domains of life.http://www.creative-enzymes.com/product/Native-Rat-Arginase_1520.html

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Nilotinib (AMN-107) LAB GRADE 97%

Nilotinib (AMN-107) can inhibit Bcr-Abl with IC50 of 30 nM. More information please visit the website: http://www.creative-enzymes.com/product/Nilotinib-AMN107-_2224.html

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Bafetinib (INNO-406) LAB GRADE 97%

Bafetinib (INNO-406) More information please visit the website: http://www.creative-enzymes.com/product/Bafetinib-INNO406-_2229.html

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Docetaxel (Taxotere) LAB GRADE 97%

Docetaxel (Taxotere) can inhibit microtubule disassembly with IC50 of a range of 0.31-100 nM. More information please visit the website: http://www.creative-enzymes.com/product/Docetaxel-Taxotere-_2231.html

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Native Bovine Aprotinin LAB GRADE

Aprotinin is a competitive serine protease inhibitor that forms stable complexes with and blocks the active sites of enzyme. This binding is reversible, and most aprotinin-protease complexes will dissociate at extreme pH levels >10 or < 3. Structurally, Aprotinin is a monomeric globular protein derived from bovine lung that consists of 58 amino acids, arranged in a single polypeptide chain with three crosslinking disulfide bridges.http://www.creative-enzymes.com/product/Native-Bovine-Aprotinin_831.html
 

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Native H. pylori Urease LAB GRADE

Ureases (EC 3.5.1.5), functionally, belong to the superfamily of amidohydrolases and phosphotriesterases. It is an enzyme that catalyzes the hydrolysis of urea into carbon dioxide and ammonia. The reaction occurs as follows: (NH2)2CO + H2O → CO2 + 2NH3.http://www.creative-enzymes.com/product/Native-H-Pylori-Urease_775.html
 

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Native Jack bean Urease LAB GRADE

Ureases (EC 3.5.1.5), functionally, belong to the superfamily of amidohydrolases and phosphotriesterases. It is an enzyme that catalyzes the hydrolysis of urea into carbon dioxide and ammonia. The reaction occurs as follows: (NH2)2CO + H2O → CO2 + 2NH3.http://www.creative-enzymes.com/product/Native-Jack-Bean-Urease_776.html
 

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PCI-32765(Ibrutinib) LAB GRADE 97%

PCI-32765(Ibrutinib) can inhibit bruton tyrosine kinase (Btk) with IC50 of 0.46 nM. More information please visit the website: http://www.creative-enzymes.com/product/PCI32765-Ibrutinib-_2227.html

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