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Polypeptide Hormone Follistatin 315 Antibody Fst-315

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Polypeptide Hormone Follistatin 315 Antibody Fst-315
 
Follistatin 315 Basic Info.
 
Product Name: Follistatin 315 / Fst-315
Specification: 1mg/vial
Purity: 85%+
Appearance: White powder
Specific Optical Rotation (c=0.5,10% HAc): -50.0~-60.0°
Water Content(Karl Fischer): ≤5.0%
Acetate Content(by HPLC): ≤15.0%
Amino Acid Composition: ±10% of theoretical
Purity (by HPLC): ≥98.0%
Single Impurity(by HPLC): ≤1.0%
Peptide Content(by %N): ≥80%
Assay(By Anhydrous, Acetic Acid-free ) :95.0~105.0%
Bacterial Endotoxins: ≤5EU/mg
Storage/Stability: Stored at -20 °C if preferred. Storage in frost-free freezers is not recommended.
Note: This product is furnished for LABORATORY RESEARCH USE ONLY. Not for diagnostic or therapeutic use.
 
Description of Follistatin 315:
 
Follistatin is being studied for its role in regulation of muscle growth in mice, as an antagonist to myostatin (also known as GDF-8, a TGF superfamily member) which inhibits excessive muscle growth. Lee & McPherron demonstrated that inhibition of GDF-8, either by genetic elimination (knockout mice) or by increasing the amount of follistatin, resulted in greatly increased muscle mass.In 2009, research with macaque monkeys demonstrated that regulating follistatin via gene therapy also resulted in muscle growth and increases in strength. This research paves the way for human clinical trials, which are hoped to begin in the summer of 2010 on Inclusion body myositis.
A study has also shown that increased levels of follistatin, by leading to increased muscle mass of certain core muscular groups, can increase life expectancy in cases of spinal muscular atrophy (SMA) in animal models.
It is also being investigated for its involvement in polycystic ovary syndrome (PCOS), though there is debate as to its direct role in this infertility disease.
 
Follistatin 315 Application:
 
Follistatin 315 primary function is the binding and bioneutralization of members of the TGF-β superfamily, with a particular focus on activin, a paracrine hormone.
 
Storage Instruction
Store at +4°C or at -20°C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
 

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Supply High Purity Dimethyl Sulfoxide / DMSO 67-68-5

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Email: tony@kafenbio.com

WhatsApp: +8618002259573

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Supply High Purity Dimethyl Sulfoxide / DMSO 67-68-5
 
Dimethyl Sulfoxide Basic Info.:
 
Product Name: Dimethyl Sulfoxide (DMSO)
Synonyms: (CH3)2SO; A 10846;a10846; Decap; Deltan; Demasorb; Demavet; Demeso; DMSO
CAS: 67-68-5
MF: C2H6OS
MW: 78.13
EINECS: 200-664-3
Melting point: 18.4 °C
Boiling point: 189 °C(lit.)
Density: 1.100 g/mL at 20 °C
Vapor density: 2.7 (vs air)
Vapor pressure: 0.42 mm Hg ( 20 °C)
Refractive index: n20/D 1.479(lit.)
Fp: 192 °F
Storage temp.: Store at RT.
Chemical Properties: colourless liquid
Freezing Point: 18.4°C
Sensitive: Hygroscopic
Stability: Stable. Incompatible with a very wide range of materials, including acid chlorides, strong acids, strong oxidizing agents, strong reducing agents, phosphorus halides, moisture, copper wool + trichloroacetic acid. Reacts violently with a number of materials - consult a full data sheet before use. Hygroscopic.
 
Dimethyl Sulfoxide Description:
 
Dimethyl sulfoxide (DMSO) is organic sulfide compound. It is colorless, odorless and transparent liquid at room temperature. It is a kind of moisture absorption combustible liquid. It has characteristics of high polarity, high boiling point, non-proton, mixed with water, low toxicity and good heat stability. It is soluble in ethanol, propanol, benzol, chloroform and many organic matters. It was known as "Omnipotent Solvent"
Dimethyl sulfoxide (DMSO) can be widely used as solvent and reaction reagent, especially as processing solvent and laddering solvent in the acrylonitrile polymerization reaction, and synthetic solvent and laddering solvent for polyurethane, also for polyamide, polyimide, polysulfone resin, aromatic hydrocarbon, butadiene and Chlorofluoroaniline etc.
Moreover, Dimethyl sulfoxide (DMSO) has the functions of anti-inflammatory analgesic, diuresis and mitigation. It is added in dugs as analgesia ingredient. It also known as "Omnipotent Drug"
 
Dimethyl Sulfoxide Use:
 
DMSO is a polar aprotic solvent used in chemical reactions, in polymerase chain reactions (PCR) and as a cryoprotectant vitrification agent for the preservation of cells, tissues and organs. DMSO is used in cell freezing media to protect cells from ice crystal induced mechanical injury. It is used for frozen storage of primary, sub-cultured, and recombinant heteroploid and hybridoma cell lines; embryonic stem cells (ESC), and hematopoietic stem cells. DMSO is frequently used in the combinations with BSA or fetal bovine serum (FBS).
 
Human and animal cell lines grown in culture are generally stored frozen. Freezing protects the cell line from changes due to genetic drift and minimizes risk of contamination. Liquid nitrogen used in conjunction with a cryoprotective agent such as DMSO is a widely used method for preserving cells. Without the presence of a cryoprotective agent, freezing is lethal to most mammalian cells. Damage is caused by mechanical injury by ice crystals, concentration of electrolytes, pH changes, and denaturation of proteins. These lethal effects are minimized by adding a cryoprotective agent which lowers.
 
Dimethyl sulfoxide (1-10%) has been shown to accelerate strand renaturation and is believed to give the nucleic acid thermal stability against depurination. As a PCR cosolvent, DMSO may help improve yields, especially in long PCR.
 

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[4-(4-Fluoro-phenyl)-1-methyl-piperidin-3-yl]-methanol is used as intermediate for the drug Paroxetine.

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3-[(1S)-1-(Dimethylaminoethyl)]phenol hydrochloride 99%

Ansion Pharma is a factory for Rivastigmine intermediate, more infomation, pls contact us: ann.xu@ansionpharma.com ;  www.ansionpharma.com

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