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Peptides Alarelin Acetate For Ovulation And Endmometriosis 79561-22-1

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Peptides Alarelin Acetate For Ovulation And Endmometriosis 79561-22-1 
Alarelin Acetate Basic Info.:
Product Name: Alarelin Acetate
Synonyms: Des-Gly10,[D-Ala6]-Lh-Rh Ethylamide Acetate Salt.
CAS: 79561-22-1
MF: C56H78N16O12
MW: 1167.32
Storage temp.: −20°C
Form: Powder
Product Categories: Amino Acid Derivatives;Peptide;LH-RH;LH-RHPeptides for Cell Biology;Neuropeptides;Releasing Factors;API.
Alarelin Acetate (79561-22-1) Description:
Alarelin acetate is a gondatrophin releasing hormone. Natural forms of alarelin found in animals are used to induce ovulation. Synthetic versions of this product are created using an LH-RH antagonist which is commonly set in larger doses than the natural LH-RH that is typically found in the rat hypophyseal stimulation or the gondatoropin secretions in induced ovulation or in vitro.
This chemical is the acetate form of the natural hypothalamic peptide which is used by an animal’s body to release LH and FSH from the pituitary gland. The peptide alarelin acetate has a single non-glycosylated polypeptide structure that is made up of nine amino acids. This has a molecular mass of 1167.3.
Alarelin is commonly used in research settings both to better understand this peptide’s effects on an animal’s body and to induce conditions that may assist with reproductive research. Samples of this chemical intended for research settings are typically stable for around three weeks at room temperature, and will need to be stored at temperatures below -18 degrees Celsius for long term use.
Most versions of this chemical are shipped as a lyophilized powder that can be reconstituted at a sterile temperature. This chemical may remain stable for up to three weeks at room temperature if it is kept sealed when it is not in use. If this product will be used for long periods of time is should be kept in a freezer with a waterproof sea.
If the mixture has already been reconstituted it can be kept at 40 degrees Celsius for 2-7 days but should be kept at -180 degrees Celsius for longer periods of time. Do not continually refreeze and thaw the product.

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Peptides Carbetocin Acetate Contracting Uterus Control Bleeding 37025-55-1

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Peptides Carbetocin Acetate Contracting Uterus Control Bleeding 37025-55-1
Carbetocin Acetate Basic Info.:
Product Name: Carbetocin Acetate
Synonyms: (Butyryl1,Tyr(Me)2)-1-Carbaoxytocin Trifluoroacetate Salt;Carbetocin;Carbetocin Trifluoroacetate Salt;
CAS: 37025-55-1
MF: C45H69N11O12S
MW: 988.17
EINECS: 253-312-6
Storage temp.: -15°C
Product Categories: Peptide;Vasopressin and Oxytocin receptor;Intermediates & Fine Chemicals;Pharmaceuticals;Other APIs
Usage: An obstetric drug used to control postpartum hemorrhaging.
Carbetocin Acetate it is used to control bleeding after giving birth. Like oxytocin, it causes contraction of the uterus.

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Perfluoroethyl Iodide

Perfluoroethyl iodide is used as pharmaceutical intermediate, agrochemical intermediate.

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Pharma Antiviral Agents Tenofovir Disoproxil Fumarate 202138-50-9 For Medicine Ingredients

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Pharma Antiviral Agents Tenofovir Disoproxil Fumarate 202138-50-9 For Medicine Ingredients


Tenofovir Basic Info.:


Product Name: Tenofovir


MF: C9H14N5O4P



storage temp. Store at -20°C

Water Solubility :13.4 mg/mL (25 ºC)

Chemical Properties:White Crystalline Solid

Usage:Acyclic phosphonate nucleotide analogue. Used as an anti-HIV agent

Usage:Acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral.

Usage:Tenofovir blocks reverse transcriptase and hepatitis B virus infections.

Biological Activity Selectively inhibits HIV reverse transcriptase (RNA-dependent DNA polymerase). Prevents cytotoxicity in SIV-infected C-8166 cells in vitro (IC 50 = 1.5 μ M). Antiviral agent.


Tenofovir Usage And Synthesis:


1. Antiviral drugs, Tenofovir is an acyclic nucleoside antiviral reverse transcriptase inhibitor. The active substance is Tenofovir disoproxil, while tenofovir is a prodrug that is used because of its better absorption in the gut.

2. Tenofovir can inhibit viral polymerase through direct competitively combine with natural deoxyribose or by insertion to terminate chain of human DNA. It is the first nucleotide analogs to treat HIV-1 infection that approved by the US Food and Drug Administration (FDA).

3. Tenofovir is a main medicine in AIDS cocktail therapy, researches has shown that it can effectively improve the monkeys` ability on prevention of immunodeficiency virus (similar to the human AIDS virus).


Tenofovir Pharmacokinetics:


Tenofovir is hardly absorbed through the gastrointestinal tract, for this reason, prodrug of Tenofovir has been developed by esterification, and then to make tenofovir fumarate ester. Tenofovir ester is water-soluble, can be rapidly absorbed and degraded into the active tenofovir, and then was metabolized to the active Tenofovir disoproxil. Tenofovir will reach the peak of plasma Concentration within 1-2 h after administration. When combined with food service, the bioavailability of Tenofovir can be increased by 40%. Intracellular half-life of Tenofovir disoproxil is about 10 h, it needs dosing everyday. Because Tenofovir is not a CYP-450 substrate, this may decrease the possibility of interactions with other drugs caused by CYP450. Elimination of Tenofovir is by glomerular filtration and active tubular secretion. Approximately 70% to 80% is recovered in urine as unchanged drug. Elimination half-life is approximately 17 h.


Indications: Tenofovir is indicated for the treatment of HIV, HBV infection. This product also can cooperated with other reverse transcriptase inhibitors for HIV-1 infection and hepatitis B treatment.


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Pharmaceutical Aerosols Hfa-134A Purified ?99.99

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Pharmaceutical product HFA-134A (P) obtained in 2016 the DMF file number in USA

HFA-134 Chemical Name: Pharmaceutical Excipients Tetrafuoroethane

The Relative Name: Aerosol Medication, Propellant Hfa-134a, Prokinetic Agents, Propellant R134a, Aerosol Inhaler, Inhalation Aerosol, Hfa Inhaler

Cas No.: 711-97-2

Molecular Formula: CH2FCF3         

Physical Properties:

Molecular weight(g/mol):  102.3         Melting point℃: -103.15℃

r134a boiling point: -26.1℃

Density of liquid (25℃ ): 1.207 g/cm3     Vapour pressure(25℃): 0.665MPa

Critical temperature (℃): 101.1           Critical pressure: 4.067 MPa

R134a Density: 1.206g/cm3             Latent heat of evaporation in boiling point: 215.0KJ/kg

Solubility in water (25℃): 0.15 W%       Specific heat (25℃ liquid): 1.51 KJ/kg . k 

ODP: 0                              GWP(100yr): 1200 

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Pharmaceutical Chemicals Isotretinoin Accutane For AcneTreatment 4759-48-2

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Pharmaceutical Chemicals Isotretinoin Accutane For AcneTreatment 4759-48-2

Isotretinoin Basic Info.:

Product Name: Isotretinoin

Synonyms: 13-ra;Accutane;Isoretinoin;Isotrex;Neovitaminaacid;Ro-4-3780

CAS: 4759-48-2

MF: C20H28O2

MW: 300.44

Assay: 99%

EINECS: 225-296-0

Product Categories: Antibiotics;Organic acids;APIs;Intermediates & Fine Chemicals;Pharmaceuticals;Retinoids

Air & Water Reactions: Insoluble in water.

Packing:100g/foil bag

Chemical Property: The melting point of 174~175 Centigrade.

UV maximum absorption: 354nm ( 39800).

Usage: Used as a treatment for severe acne. Presently being studied in conjuction with the treatment of photoaged skin.

Isotretinoin Usage:

As the retinoid, there are strong and fast proliferation inhibition and differentiation of skin gland cell function, effective on severe nodular cystic acne. The gastrointestinal absorption is better, while the local medication invalid. Other drugs used to treat invalid serious acne, cystic acne, acne conglobata, rosacea, ichthyosis, keratosis follicularis and pityriasis rubra pilaris and other skin diseases also have a certain effect. For severe acne. Anti skin dyskeratosis medicine. For the treatment of severe acne and other disorders. Belong to whitening prohormones, can made INTO injections! Works very well in whitening!

Application Of Isotretinoin:

1. Medical applications: the lack of nutrition of the elderly, thin, for severe burns and had the operation people.

2. Sports purpose: promote muscle growth, increased training and endurance training load, it has never been proved.

3. Adaption: Trauma, chronic infection, malnutrition and wasting disease and All kinds of refractory anemia.


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Pharmaceutical Grade Epicatechin White Powder CAS 490-46-0 L-Epicatechin

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Pharmaceutical Grade Epicatechin White Powder CAS 490-46-0 L-Epicatechin
L-Epicatechin Basic Info.:
Product Name: L-Epicatechin
Synonym: 2-(3,4-dihydroxyphenyl)-2,3,4-trihydro-3,5,7-trihydroxychromene; EPICATECHIN;
CAS No.: 490-46-0
EINECS No.: 207-710-1
Molecular formula: C15H14O6
Molecular weight: 290.27
Packing: 25KG/Drum
Content: 95%
Appearance: White powder
Grade: Pharmaceutical Grade
Category: Plant Extract
L-Epicatechin Function:
1. Prevent wrinkle;
2. Prevent sunscreen, freckle;
3. Remove heavy metals toxicity;
4. Fight bacterium diminish inflammation;
5. Promote skin microcirculation;
6. Anti skin cancer.
L-Epicatechin Application:
1. In medicationandHealth, can prevent cancer, improve immunity.
2. In food industry it can be as Anti-oxidant, antibacterial, preservation, expelling smelly agent.
3. In cosmetic products.

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Pharmaceutical Grade Raw Material Chitosan CAS 9012-76-4 For Food

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Pharmaceutical Grade Raw Material Chitosan CAS 9012-76-4 For Food
Chitosan Basic information
Product Name: Chitosan
CAS: 9012-76-4
MF: C6H11NO4X2
MW: 161.16
EINECS: 222-311-2
Storage temp.: room temp
Solubility: dilute aqueous acid (pH <6.5).: soluble
Stability: Stable. Incompatible with strong oxidizing agents.
Chemical Properties: faintly beige solid  (Coarse ground flakes and powder)
Product Categories: Miscellaneous Natural Products;Biochemistry;Polysaccharides;Sugars;Nutritional Supplements;Dextrins、Sugar & Carbohydrates;Activity Other;Carbohydrate adjuvants;Carbohydrates A-C;Chitosan and Chitin;Activity;and Substrates;Biochemicals and Reagents;Carbohydrates;Carbohydrates A to Z;Cell Culture;Chitosan;Enzyme Substrates;Enzymes;Inhibitors;Materials Science;Natural Polymers;Polymer Science;Polymers;Polysaccharide;Vaccine Adjuvants;Vaccine Production;Oligosaccharide,Biostimulate
Usage: Claimed to have the ability to retain fats and cholesterol in the stomach.
Properties: This product is non-toxic, odorless, off-white or slight yellow powder, and soluble in acid, insoluble in water and base or normal organic solutions.
Chitosan Description:
Chitosan is a linear polysaccharide composed of randomly distributed β-(1-4)-linked D-glucosamine (deacetylated unit) and N-acetyl-D-glucosamine (acetylated unit). It is made by treating shrimp and other crustacean shells with the alkali sodium hydroxide.
Chitosan has a number of commercial and possible biomedical uses. It can be used in agriculture as a seed treatment and biopesticide, helping plants to fight off fungal infections. In winemaking it can be used as a fining agent, also helping to prevent spoilage. In industry, it can be used in a self-healing polyurethane paint coating. In medicine, it may be useful in bandages to reduce bleeding and as an antibacterial agent; it can also be used to help deliver drugs through the skin.
More controversially, chitosan has been asserted to have use in limiting fat absorption, which would make it useful for dieting, but there is evidence against this.
Other uses of chitosan that have been researched include use as a soluble dietary fiber.
Chitosan is extracted from chitin, insoluble in water but soluble in dilute acid and absorbed by human body. As the firdt derivate, it's chemical constitution is macromolecule alkalescent polysaccharide polymer with cation. It has peculiar physical, chemical properties and bioactive function.
Chitosan is listed as follows:
A. High Density Chitosan
B. High Viscosity Chitosan
C. Industrial Grade Chitosan
D. Food Grade Chitosan
E. Medical Grade Chitosan
F. Low Molecular Weight Chitosan
G. Aroxymethyl Chitosan
H. Chitosan Oligosaccharide
Chitosan Applications:
1)Food Field:
Used as food additives, thickeners, preservatives fruits and vegetables, fruit juice clarifying agent, forming agent, adsorbent, and health food.
2)Medicine, health care products field:
As the chitosan non-toxic,has anti-bacterial, anti-inflammatory, hemostatic, and immune function, can be used as artificial skin, self-absorption of surgical sutures, medical dressing Branch, bone, tissue engineering scaffolds, enhance liver function, improve digestive function, blood fat, lowering blood sugar, inhibiting tumor metastasis, and adsorption and complexation of heavy metals and can be excreted, and so on, was vigorously applied to health food and drug additives.
3)Environmental protection field:
Chitosan and its derivatives is a good flocculant for wastewater treatment and metal recovery from metal-containing waste water; in textile field: as a mordant, health care fabric, sizing agents, printing and dyeing
4).Agricultural field:
As growth promoters, bio-pesticides, feed additives, seeds, etc.
5)Field of tobacco
Tobacco sheet used as adhesives, low-tar filter and so on.
Chitosan is refined from deacetylation of chitin which is extracted from deep-sea Alaska crab cods. As the only basic polysaccharide among natural polysaccharides, this product has many physical and chemical characteristics and physiological activities. Precisely, this product can control cholesterol, inhibit bacterial activity, prevent and control high blood pressure, absorb and excrete heavy metals, maintain humidity and strengthen immunity. In food industry, this product can be used as antibacterial agent, fruit and vegetable preservative and antioxidant. There are many special functional groups in molecular chain, so the chitosan can be manufactured into many products according to different reactions on functional groups, such as acylation, sulfation and oxidation, grafting and crosslinking, hydroxyethylation and hydroxymethylation. These products can be used in many fields, including medicine, food, chemical, cosmetic, water treatment, metal extraction and recovery, biochemical and biomedical engineering. There are many types of chitosan, including GS-chitosan oligosaccharide, high density type, special molecular weight type, medical/food / industrial grade type, water soluble type and specialized type.
Chitosan can inhibit growth and reproduction of fungi, bacteria, and virus. When this product is used as coating preservation, it can inhibit respiratory metabolism and water loss of fruits and vegetables, thus slowing their aging process of organization and structure and effectively extending their postharvest life. This product can also be used as antioxidant. In heating process, free iron ions are released from meat hemoglobin and they form chelates with chitosan, thus their catalytic activity is inhibited.
Chitosan Usage:
Agricultural and horticultural use
The agricultural and horticultural uses for chitosan, primarily for plant defense and yield increase, are based on how this glucosamine polymer influences the biochemistry and molecular biology of the plant cell. The cellular targets are the plasma membrane and nuclear chromatin. Subsequent changes occur in cell membranes, chromatin, DNA, calcium, MAP Kinase, oxidative burst, reactive oxygen species, callose pathogenesis-related (PR) genes and phytoalexins.
Natural biocontrol and elicitor
In agriculture, chitosan is used primarily as a natural seed treatment and plant growth enhancer, and as an ecologically friendly biopesticide substance that boosts the innate ability of plants to defend themselves against fungal infections. The natural biocontrol active ingredients, chitin/chitosan, are found in the shells of crustaceans, such as lobsters, crabs, and shrimp, and many other organisms, including insects and fungi. It is one of the most abundant biodegradable materials in the world.

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Pharmaceutical Grade Reducing Fat Mass Chemicals Sr9011 SR-9011 1379686-29-9

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Pharmaceutical Grade Reducing Fat Mass Chemicals Sr9011 SR-9011 1379686-29-9
SR9011 Basic Info:
Product Name: SR9011
Synonyms: 3-(((4-chlorobenzyl)((5-nitrothiophen-2-yl)methyl)amino)methyl)-N-pentylpyrrolidine-1-carboxamide
CAS No: 1379686-29-9
Molucelar Formula: C23H31ClN4O3S
Molucelar Weight: 479.03524
Solubility: DMSO up to 100 mM
Sr9011 Description:
SR9011 is a trifunctional methacrylate monomer that provides exceptional adhesion to metal substrates.
SR9011 is recommended for use in peroxide cured coatings, sealants, and PVC-based plastisols. Usage levels of 5% to 10% by weight are recommended.
SR9011 is a potent and specific synthetic REV-ERB agonist that binds to REV ERB α with an EC50 ~790 nM and REV-ERB-β with EC50 ~560 nM. It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB-α and REV-ERB-β play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism. Administration of SR9011 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice. The circadian expression pattern of an array of metabolic genes in the liver, skeletal muscle and adipose tissue was also altered, resulting in increased energy expenditure. Treatment of diet induced obese mice with SR9011 decreased obesity by reducing fat mass and markedly improved dyslipidaemia and hyperglycaemia. These results indicate that synthetic REV-ERB ligands that pharmacologically target the circadian rhythm may be beneficial in the treatment of sleep disorders as well as metabolic diseases.
Sr9011 Application:
In vitro: SR9011 was used at 5-10 μM concentration in vitro and in cellular assays.
In vivo: IP administration of SR9011 was used at 100 mg/kg once or twice per day for 12-30 days in different mouse models.

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