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Pharmaceutical Human Growth Hormone Peptide TB-500 Anti Inflammatory
TB 500 Basic Info.:
Product Name: TB 500
Synonyms:TB 500;TB500;Thymosin Beta 500
TB500 Appearance: White powder
TB500 CAS No.: 77591-33-4
TB500 MF: C212H350N56O78S
TB500 MW: 4963.49
TB500 Specification: 2mg/vial,10vials/kit
TB500 Purity (HPLC): 95%min
TB500 Amino Acid Composition: ± 10% of theoretical
TB500 Peptide Content (N%): ≥ 80.0%
TB500 Water Content(Karl Fischer): ≤ 5.0%
TB500 Acetate Content (HPIC): ≤ 15.0%
TB500 Single Impurity (HPLC): 2.0%max
TB500 MS(ESI): Consistent
TB 500 Description:
TB-500 is a synthetic fraction of the protein thymosin beta-4, which is present in virtually all human
and animal cells. The main purpose of this peptide is to promote healing. It also promotes creation
of new blood and muscle cells. The healing effects of TB-500 have been observed in tendons,
ligaments, muscle, skin, heart, and the eyes. Thymosin beta-4 is naturally produced in higher
concentration where tissue has been damaged. This peptide is also a very potent anti-inflamatory
agent.
TB-500 is different from other repair factors (growth hormone, IGF-1), because it promotes
endothelial and keratinocyte migration. It also does not bind to the extracellular matrix and has
a very low molecular weight. Because of this it can travel long distances through the tissues in the
human body.
One of TB-500 key mechanisms of action is its ability to regulate the cell-building protein - Actin.
Of the thousands of proteins present within human cells, actin represents roughly 10% of the total.
It is thus a vital component of cell structure and movement.
TB-500 was identified as a gene that was up-regulated four-to-six fold during early blood vessel
formation and found to promote the growth of new blood cells from the existing vessels. This peptide is present in wound fluid and when administered subcutaneously, it promotes wound healing, muscle building and speeds up recovery time of muscles fibres and their cells. An additional key factor of
TB-500 is that it promotes cell migration through a specific interaction with actin in the cell cytoskeleton.
It has been demonstrated that a central small amino acid long-actin binding domain has both blood cell reproduction and wound healing characteristics. These characteristics are uncovered by accelerating
the migration of endothelial cells and keratinocytes. It also increases the production of extracellular matrix-degrading enzymes.
TB 500 Application:
TB-500 is different from other repair factors because it promotes endothelial and keratinocyte migration. It also does not bind to the extracellular matrix and has a very low molecular weight.Because of this it can travel long distances through the tissues in the human body.
TB-500 is a synthetic fraction of the protein thymosin beta-4, which is present in virtually all human and animal cells. The main purpose of this peptide is to promote healing. It also promotes creation of new blood and muscle cells. The healing effects of TB-500 have been observed in tendons, ligaments, muscle, skin, heart, and the eyes. Thymosin beta-4 is naturally produced in higher concentration where tissue has been damaged. This peptide is also a very potent anti-inflamatory agent.
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